Development Level

Tbio 203 | 10,625
Tchem 54 | 1,890
Tclin 21 | 602
Tdark 8 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, incomple... 9 | 260
enlarged heart 6 | 111
decreased bone mineral content 5 | 157
impaired glucose tolerance 5 | 52
preweaning lethality, complete... 5 | 633
decreased bone mineral density 4 | 126
decreased circulating HDL chol... 4 | 77
decreased lean body mass 4 | 195
increased circulating alkaline... 4 | 119
abnormal seminal vesicle morph... 3 | 47
abnormal sleep behavior 3 | 63
decreased body length 3 | 108
decreased circulating insulin ... 3 | 75
decreased mean corpuscular vol... 3 | 50
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
increased blood urea nitrogen ... 3 | 44
increased circulating potassiu... 3 | 31
increased hemoglobin content 3 | 45
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
short tibia 3 | 82
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal coping response 2 | 12
abnormal embryo size 2 | 112
abnormal heart morphology 2 | 51
abnormal locomotor activation 2 | 26
abnormal lung morphology 2 | 15
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
cardiovascular system phenotyp... 2 | 35
decreased blood urea nitrogen ... 2 | 31
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 34
decreased prepulse inhibition 2 | 52
enlarged spleen 2 | 26
increased circulating HDL chol... 2 | 63
increased circulating calcium ... 2 | 32
increased circulating sodium l... 2 | 71
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased or absent threshold ... 2 | 128
male infertility 2 | 62
premature death 2 | 5
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal cornea morphology 1 | 24
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal liver morphology 1 | 5
abnormal neural tube closure 1 | 37
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal urinary bladder morph... 1 | 2
corneal opacity 1 | 25
decreased circulating bilirubi... 1 | 14
decreased circulating iron lev... 1 | 25
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 19
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
female infertility 1 | 34
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired righting response 1 | 19
increased NK T cell number 1 | 11
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased mean corpuscular vol... 1 | 91
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
lethargy 1 | 5
limb grasping 1 | 35
oligodactyly 1 | 14
pallor 1 | 13
small seminal vesicle 1 | 6
small testis 1 | 37
straub tail 1 | 26

Disease

ovarian cancer 155 | 8,484
psoriasis 132 | 6,685
lung cancer 130 | 4,466
osteosarcoma 130 | 7,933
lung carcinoma 118 | 2,844
glioblastoma 104 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 100 | 2,956
non-small cell lung cancer 99 | 2,798
invasive ductal carcinoma 97 | 2,950
lung adenocarcinoma 96 | 2,713
pilocytic astrocytoma 96 | 3,086
medulloblastoma, large-cell 93 | 6,234
Cancer 92 | 2,346
ulcerative colitis 87 | 2,087
pancreatic ductal adenocarcinoma liver metastasis 86 | 1,795
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 82 | 3,289
malignant mesothelioma 81 | 3,162
interstitial cystitis 80 | 2,299
pancreatic cancer 76 | 2,300
Carcinoma 75 | 2,147
Breast cancer 69 | 3,094
ductal carcinoma in situ 67 | 1,745
atypical teratoid / rhabdoid tumor 65 | 4,369
tuberculosis 60 | 1,557
pediatric high grade glioma 59 | 2,712
breast carcinoma 58 | 1,614
cystic fibrosis 58 | 1,665
colon cancer 57 | 1,475
subependymal giant cell astrocytoma 57 | 2,287
diabetes mellitus 55 | 1,663
posterior fossa group A ependymoma 55 | 1,511
oligodendroglioma 53 | 2,849
pituitary cancer 53 | 1,972
adrenocortical carcinoma 47 | 1,427
gastric carcinoma 45 | 832
Duchenne muscular dystrophy 44 | 602
juvenile dermatomyositis 44 | 1,189
primary pancreatic ductal adenocarcinoma 44 | 1,271
astrocytoma 43 | 1,493
Kidney disease 42 | 396
Atopic dermatitis 41 | 944
Rheumatoid Arthritis 40 | 1,160
primitive neuroectodermal tumor 39 | 3,031
Atherosclerosis 38 | 275
ependymoma 38 | 2,514
group 3 medulloblastoma 38 | 2,254
esophageal adenocarcinoma 37 | 737
adult high grade glioma 36 | 2,148
astrocytic glioma 36 | 2,241
cutaneous lupus erythematosus 35 | 1,056
group 4 medulloblastoma 34 | 1,875
sonic hedgehog group medulloblastoma 34 | 1,482
Vascular disease 33 | 281
Coronary artery disease 32 | 240
dermatomyositis 32 | 933
primary Sjogren syndrome 32 | 789
mucosa-associated lymphoid tissue lymphoma 31 | 480
acute quadriplegic myopathy 30 | 1,157
active Crohn's disease 29 | 918
Cerebrovascular disease 28 | 231
Hypertension 27 | 287
Obesity 27 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 27 | 499
IGA Glomerulonephritis 26 | 454
nasopharyngeal carcinoma 25 | 1,056
Alzheimer's disease 23 | 644
Down syndrome 23 | 548
Liver disease 22 | 219
Pick disease 22 | 1,893
Prostatic Neoplasms 22 | 471
fibroadenoma 22 | 557
nephrosclerosis 22 | 329
Becker muscular dystrophy 21 | 187
Endometriosis 21 | 535
Anemia 20 | 252
Arthritis 20 | 248
Multiple Sclerosis 19 | 498
limb girdle muscular dystrophy 2A 19 | 156
posterior fossa group B ependymoma 19 | 1,530
urothelial carcinoma 19 | 318
Asthma 18 | 349
Schizophrenia 18 | 501
atypical teratoid/rhabdoid tumor 18 | 1,095
head and neck cancer and chronic obstructive pulmonary disease 18 | 237
pancreatic carcinoma 18 | 567
Heart disease 17 | 279
Hypertensive disease 17 | 193
Thrombophilia 17 | 36
aldosterone-producing adenoma 17 | 664
chronic rhinosinusitis 17 | 512
Hypersensitivity reaction type II disease 16 | 235
Thrombocytopenia 16 | 105
medulloblastoma 16 | 1,524
Liver carcinoma 15 | 217
Lung disease 15 | 132
Peripheral Neuropathy 15 | 303
sarcoidosis 15 | 358
Autistic Disorder 14 | 320
Mammary Neoplasms 14 | 410

Tissue

Liver and Pancreas 286 | 18,136
Nervous System 286 | 18,561
Urinary Tract 286 | 18,444
Cardiovascular System 285 | 17,958
Digestive Tract 285 | 18,473
Endocrine System 285 | 18,512
Female tissues 285 | 18,647
Blood and immune system 284 | 17,995
Male tissues 284 | 17,969
Skin and soft tissues 283 | 18,115
Respiratory system 282 | 17,484

Target Family

Non-IDG 200 | 11,971
Enzyme 71 | 4,146
Kinase 6 | 634
GPCR 5 | 406
Transporter 2 | 473
Ion Channel 1 | 341
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Plasma cell 286 | 286
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Properdin CFP Tbio Non-IDG -3.16935 1491.5 297
Coagulation factor XI F11 Tchem Enzyme -2.65863 487.3 216
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
Laminin subunit alpha-2 LAMA2 Tbio Non-IDG -2.48634 321.9 131
Tenascin-N TNN Tbio Non-IDG -1.77329 68.8 63
Fibrinogen alpha chain FGA Tbio Non-IDG -2.84597 716.2 457
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.80284 593.9 352