Development Level

Tbio 214 | 11,651
Tchem 42 | 1,388
Tclin 21 | 612
Tdark 7 | 6,593

Collection

GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 13 | 499
abnormal seminal vesicle morph... 6 | 114
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
enlarged heart 6 | 210
decreased mean corpuscular vol... 5 | 79
embryonic lethality prior to t... 5 | 278
impaired glucose tolerance 5 | 75
preweaning lethality, complete... 5 | 979
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
decreased blood urea nitrogen ... 4 | 51
increased heart weight 4 | 62
abnormal sleep behavior 3 | 70
cardiovascular system phenotyp... 3 | 36
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
embryonic growth retardation 3 | 106
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
short tibia 3 | 97
abnormal bone structure 2 | 187
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
enlarged spleen 2 | 41
hypoactivity 2 | 132
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
male infertility 2 | 123
premature death 2 | 5
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent vibrissae 1 | 12
corneal opacity 1 | 32
decreased body length 1 | 101
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased exploration in new e... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
dilated heart left ventricle 1 | 11
hydrometra 1 | 53
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
persistence of hyaloid vascula... 1 | 33
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
trunk curl 1 | 16

Disease

Carcinoma 222 | 11,493
ovarian cancer 155 | 8,520
lung cancer 132 | 4,740
psoriasis 132 | 6,694
osteosarcoma 128 | 7,950
lung carcinoma 118 | 2,843
glioblastoma 111 | 5,792
non-small cell lung cancer 101 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 99 | 2,955
invasive ductal carcinoma 97 | 2,951
lung adenocarcinoma 96 | 2,716
Astrocytoma, Pilocytic 95 | 3,081
ependymoma 95 | 4,679
Cancer 94 | 2,499
medulloblastoma, large-cell 92 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 90 | 1,962
malignant mesothelioma 88 | 3,232
Breast cancer 85 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
pancreatic cancer 81 | 2,398
interstitial cystitis 80 | 2,312
Kidney cancer 78 | 2,613
atypical teratoid / rhabdoid tumor 78 | 5,112
adult high grade glioma 76 | 3,801
Autosomal recessive predisposition 72 | 1,442
ulcerative colitis 72 | 1,819
ductal carcinoma in situ 67 | 1,745
group 3 medulloblastoma 63 | 4,104
tuberculosis 62 | 2,010
cystic fibrosis 59 | 1,696
breast carcinoma 58 | 1,638
diabetes mellitus 58 | 1,728
colon cancer 57 | 1,478
subependymal giant cell astrocytoma 56 | 2,287
pituitary cancer 53 | 1,972
oligodendroglioma 52 | 2,850
Schizophrenia 49 | 1,160
Kidney disease 47 | 430
adrenocortical carcinoma 47 | 1,428
astrocytic glioma 47 | 2,597
juvenile dermatomyositis 44 | 1,187
Duchenne muscular dystrophy 43 | 601
gastric carcinoma 43 | 807
Atopic dermatitis 42 | 952
Liver Cirrhosis, Experimental 41 | 769
primary pancreatic ductal adenocarcinoma 40 | 1,109
Atherosclerosis 39 | 291
Rheumatoid arthritis 39 | 1,191
primitive neuroectodermal tumor 38 | 3,035
esophageal adenocarcinoma 37 | 737
Hypertension 36 | 396
cutaneous lupus erythematosus 35 | 1,057
Coronary artery disease 33 | 268
Vascular disease 33 | 319
astrocytoma 32 | 1,146
dermatomyositis 32 | 966
Melanoma 31 | 711
mucosa-associated lymphoid tissue lymphoma 31 | 484
Cerebrovascular disease 30 | 238
acute quadriplegic myopathy 30 | 1,158
active Crohn's disease 29 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 29 | 510
primary Sjogren syndrome 29 | 735
Liver disease 28 | 237
Obesity 28 | 678
Skin cancer 27 | 469
active ulcerative colitis 27 | 764
group 4 medulloblastoma 26 | 1,855
Bipolar Disorder 25 | 666
nasopharyngeal carcinoma 25 | 1,058
Alzheimer's disease 24 | 658
Arthritis 23 | 290
Hypertensive disease 23 | 292
Anemia 22 | 365
Becker muscular dystrophy 22 | 191
Liver cancer 22 | 604
Pick disease 22 | 1,894
Prostatic Neoplasms 22 | 495
fibroadenoma 22 | 559
limb girdle muscular dystrophy 2A 22 | 213
nephrosclerosis 22 | 333
Down syndrome 21 | 499
Depressive disorder 20 | 409
Endometriosis 20 | 540
Multiple Sclerosis 20 | 540
Chemical and Drug Induced Liver Injury 19 | 195
urothelial carcinoma 19 | 318
Asthma 18 | 385
Heart disease 18 | 306
Intellectual disability 18 | 1,016
Thrombophilia 18 | 38
head and neck cancer and chronic obstructive pulmonary disease 18 | 239
pancreatic carcinoma 18 | 562
pediatric high grade glioma 18 | 1,064
Carcinoma, Hepatocellular 17 | 228
Hypersensitivity reaction type II disease 17 | 253
Liver carcinoma 17 | 240
aldosterone-producing adenoma 17 | 665
medulloblastoma 17 | 720

Tissue

Liver and Pancreas 280 | 16,750
Digestive Tract 278 | 17,369
Urinary Tract 278 | 16,678
Endocrine System 276 | 18,159
Female tissues 273 | 17,400
Skin and soft tissues 272 | 17,230
Male tissues 270 | 17,142
Blood and immune system 265 | 16,909
Nervous System 260 | 16,725
Respiratory system 260 | 16,393
Cardiovascular System 238 | 15,192

Target Family

Non-IDG 198 | 12,091
Enzyme 71 | 4,145
Kinase 6 | 634
GPCR 5 | 408
Transporter 2 | 473
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Plasma cell 284 | 284
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
C4b-binding protein alpha chain C4BPA Tbio Non-IDG -2.43425 244.7 172
Macrophage receptor MARCO MARCO Tbio Non-IDG -2.37206 210.3 189
Inactive serine protease PAMR1 PAMR1 Tdark Enzyme -0.86262 5.98 22
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
Interleukin-6 receptor subunit beta IL6ST Tclin Non-IDG -1.72489 55.4 555
Apolipoprotein F APOF Tbio Non-IDG -1.45156 33.3 232
Protein Z-dependent protease inhibitor SERPINA10 Tbio Enzyme -1.87106 72.9 218
Endothelial lipase LIPG Tchem Enzyme -2.28530 192.2 712