Development Level

Tbio 17 | 11,651
Tdark 11 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 2 | 187
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

ovarian cancer 18 | 8,520
medulloblastoma, large-cell 16 | 6,241
psoriasis 15 | 6,694
osteosarcoma 14 | 7,950
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 12 | 5,112
Carcinoma 9 | 11,493
adult high grade glioma 9 | 3,801
lung cancer 9 | 4,740
Multiple myeloma 8 | 1,332
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
Astrocytoma, Pilocytic 7 | 3,081
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
Waldenstrons macroglobulinemia 4 | 765
cutaneous lupus erythematosus 4 | 1,057
hereditary spastic paraplegia 4 | 318
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Atopic dermatitis 3 | 952
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Cancer 2 | 2,499
Kidney cancer 2 | 2,613
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
Abdomen distended 1 | 43
Abnormality of blood and blood-forming tissues 1 | 10
Abnormality of the haematopoietic system 1 | 10
Adenoma 1 | 167
Cardiovascular system disease 1 | 246
Chylomicron retention disease 1 | 11
Cockayne syndrome 1 | 60
Diarrhea 1 | 253
Disease Progression 1 | 136
Disorder of eye 1 | 27
Elevated hepatic transaminases 1 | 81
Eye Abnormalities 1 | 35
Failure to gain weight 1 | 365
Familial atrial fibrillation 1 | 23
Growth retardation 1 | 115
Hematological Disease 1 | 18
Hepatic enzyme increased 1 | 81
Hypobetalipoproteinemias 1 | 5
Infantile onset 1 | 238
Lipid metabolism disorder 1 | 114
Liver Dysfunction 1 | 99
Liver cancer 1 | 604
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Neuroblastoma 1 | 80
Pediatric failure to thrive 1 | 365
Pituitary adenoma 1 | 38
Retinal Diseases 1 | 55
Steatorrhea 1 | 34
Stomach Neoplasms 1 | 300
Subclinical abnormal liver function tests 1 | 81
Transaminases increased 1 | 81
Vitreous detachment 1 | 10
Vomiting 1 | 116
active ulcerative colitis 1 | 764
glioblastoma multiforme 1 | 142
medulloblastoma 1 | 720
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Skin and soft tissues 29 | 17,230
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Nervous System 28 | 16,725
Cardiovascular System 27 | 15,192
Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Respiratory system 27 | 16,393
Urinary Tract 26 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 9 | 4,145
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Pituitary gland tumor cell 29 | 29
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
COMM domain-containing protein 10 COMMD10 Tdark Non-IDG -0.12222 1.52 104
28S ribosomal protein S18b, mitochondrial MRPS18B Tdark Non-IDG -0.67793 4.10 45
Peptidyl-prolyl cis-trans isomerase FKBP7 FKBP7 Tbio Enzyme -1.41965 24.7 112
Ester hydrolase C11orf54 C11orf54 Tbio Enzyme -0.36001 2.22 46
RWD domain-containing protein 1 RWDD1 Tdark Non-IDG -0.46982 2.87 93
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 ACAP1 Tbio Non-IDG -1.16973 15.4 170
Probable ATP-dependent RNA helicase DDX46 DDX46 Tbio Enzyme -1.36619 24.8 88