Development Level

Tbio 14 | 10,625
Tdark 11 | 7,003
Tchem 7 | 1,890
Tclin 3 | 602

IMPC Phenotype

preweaning lethality, complete... 3 | 633
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
abnormal embryo size 1 | 112
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating magnesiu... 1 | 11
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
increased lean body mass 1 | 107
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 19 | 8,491
osteosarcoma 15 | 7,933
medulloblastoma, large-cell 14 | 6,234
glioblastoma 10 | 5,572
lung cancer 10 | 4,473
psoriasis 10 | 6,685
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
lung carcinoma 9 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
invasive ductal carcinoma 8 | 2,950
Breast cancer 7 | 3,098
Cancer 7 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
juvenile dermatomyositis 6 | 1,189
malignant mesothelioma 6 | 3,163
oligodendroglioma 6 | 2,849
pediatric high grade glioma 6 | 2,712
Multiple myeloma 5 | 1,327
Parkinson's disease 5 | 364
adult high grade glioma 5 | 2,148
atypical teratoid / rhabdoid tumor 5 | 4,369
ependymoma 5 | 2,514
interstitial cystitis 5 | 2,299
lung adenocarcinoma 5 | 2,714
pancreatic cancer 5 | 2,300
pilocytic astrocytoma 5 | 3,086
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,031
ulcerative colitis 5 | 2,087
Alzheimer's disease 4 | 644
aldosterone-producing adenoma 4 | 664
breast carcinoma 4 | 1,614
dermatomyositis 4 | 966
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
Adenoma 3 | 165
Arthritis 3 | 248
Autistic Disorder 3 | 320
Diarrhea 3 | 155
Down syndrome 3 | 548
Hyperalgesia 3 | 71
IGA Glomerulonephritis 3 | 454
Intellectual disability 3 | 573
Migraine 3 | 79
Pain 3 | 70
Parkinson Disease 3 | 105
Phaeochromocytoma 3 | 20
Waldenstrons macroglobulinemia 3 | 764
active Crohn's disease 3 | 918
astrocytic glioma 3 | 2,241
atypical teratoid/rhabdoid tumor 3 | 1,095
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
hepatocellular carcinoma 3 | 550
non-small cell lung cancer 3 | 2,798
primary Sjogren syndrome 3 | 788
Atopic dermatitis 2 | 944
Bipolar Disorder 2 | 266
Calcinosis 2 | 63
Complex regional pain syndrome 2 | 12
Cushing's syndrome 2 | 47
Duchenne muscular dystrophy 2 | 602
Dystonia 2 | 77
Hypercalcemia 2 | 37
Hyperparathyroidism 2 | 43
Hypertension 2 | 293
Hypertensive disease 2 | 193
Hypogonadism 2 | 70
Hypophosphatemia 2 | 31
Hypothyroidism 2 | 89
Myocardial Ischemia 2 | 169
Osteogenesis imperfecta 2 | 34
Osteomalacia 2 | 28
Osteoporosis 2 | 259
Paget's disease of bone 2 | 28
Pain agnosia 2 | 99
Pancreatitis 2 | 97
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
Rickets 2 | 42
Root resorption 2 | 21
Schizophrenia 2 | 503
Thyrotoxicosis 2 | 38
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,670
gastric carcinoma 2 | 832
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
primary pancreatic ductal adenocarcinoma 2 | 1,271
spina bifida 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 34 | 17,994
Cardiovascular System 34 | 17,957
Digestive Tract 34 | 18,472
Endocrine System 34 | 18,511
Female tissues 34 | 18,646
Liver and Pancreas 34 | 18,135
Male tissues 34 | 17,968
Nervous System 34 | 18,560
Respiratory system 34 | 17,483
Skin and soft tissues 34 | 18,114
Urinary Tract 34 | 18,443

Target Family

Non-IDG 24 | 11,969
Enzyme 8 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

Jensen-KB Tissue

Pheochromocytoma cell line 35 | 35
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Bcl-2-like protein 13 BCL2L13 Tbio Non-IDG -1.54404 31.3 181
Eukaryotic translation initiation factor 2A EIF2A Tbio Non-IDG -0.57210 3.87 227
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.11491 14.8 25
Protein RTF2 homolog RTFDC1 Tdark Non-IDG 0.48 0.25 69
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.36549 229.4 425
Chromaffin granule amine transporter SLC18A1 Tchem Transporter -1.98118 94.6 91
Leucine-rich repeat-containing protein C10orf11 C10orf11 Tdark Non-IDG -0.58229 3.60 6
Membrane-spanning 4-domains subfamily A member 6A MS4A6A Tbio Non-IDG -0.91464 7.43 98
Calcitonin gene-related peptide 2 CALCB Tchem Non-IDG -1.45917 27.3 25