Development Level

Tbio 123 | 11,445
Tdark 37 | 6,588
Tchem 18 | 1,598
Tclin 6 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 7 | 298
decreased body length 5 | 101
preweaning lethality, incomple... 5 | 499
abnormal lens morphology 4 | 81
decreased bone mineral content 4 | 151
hypoactivity 4 | 132
abnormal bone structure 3 | 187
abnormal coat-hair pigmentatio... 3 | 64
abnormal embryo size 3 | 220
cataract 3 | 92
decreased bone mineral density 3 | 126
decreased fasted circulating g... 3 | 65
decreased grip strength 3 | 116
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
embryonic lethality prior to t... 3 | 278
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased total body fat amoun... 3 | 134
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
abnormal retinal blood vessel ... 2 | 26
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased circulating iron lev... 2 | 32
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
female infertility 2 | 60
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
tremors 2 | 39
abnormal brain morphology 1 | 13
abnormal forebrain development 1 | 20
abnormal head size 1 | 6
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
decreased T cell number 1 | 15
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
prenatal lethality 1 | 28
thin ventricular wall 1 | 24

Disease

Carcinoma 118 | 11,493
ovarian cancer 88 | 8,520
osteosarcoma 80 | 7,950
psoriasis 75 | 6,694
medulloblastoma, large-cell 70 | 6,241
atypical teratoid / rhabdoid tumor 64 | 5,112
glioblastoma 61 | 5,792
lung cancer 53 | 4,740
Breast cancer 50 | 3,578
adult high grade glioma 49 | 3,801
ependymoma 48 | 4,679
group 3 medulloblastoma 47 | 4,104
invasive ductal carcinoma 45 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
Astrocytoma, Pilocytic 43 | 3,081
lung adenocarcinoma 43 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
non-small cell lung cancer 38 | 2,890
oligodendroglioma 35 | 2,850
malignant mesothelioma 34 | 3,232
primitive neuroectodermal tumor 34 | 3,035
lung carcinoma 32 | 2,843
Kidney cancer 31 | 2,613
breast carcinoma 31 | 1,638
subependymal giant cell astrocytoma 29 | 2,287
astrocytic glioma 28 | 2,597
pituitary cancer 28 | 1,972
Pick disease 25 | 1,894
pancreatic cancer 25 | 2,398
Cancer 24 | 2,499
adrenocortical carcinoma 24 | 1,428
colon cancer 24 | 1,478
ductal carcinoma in situ 23 | 1,745
group 4 medulloblastoma 21 | 1,855
interstitial cystitis 20 | 2,312
acute quadriplegic myopathy 19 | 1,158
cystic fibrosis 19 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
primary pancreatic ductal adenocarcinoma 19 | 1,109
tuberculosis 19 | 2,010
Multiple myeloma 18 | 1,332
juvenile dermatomyositis 18 | 1,187
ulcerative colitis 18 | 1,819
gastric carcinoma 16 | 807
Liver Cirrhosis, Experimental 13 | 769
dermatomyositis 13 | 966
diabetes mellitus 13 | 1,728
Atopic dermatitis 12 | 952
Autosomal recessive predisposition 12 | 1,442
Duchenne muscular dystrophy 12 | 601
Liver cancer 12 | 604
aldosterone-producing adenoma 12 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
Down syndrome 10 | 499
Rheumatoid arthritis 10 | 1,191
Schizophrenia 10 | 1,160
active ulcerative colitis 10 | 764
acute myeloid leukemia 10 | 783
astrocytoma 10 | 1,146
fibroadenoma 10 | 559
non primary Sjogren syndrome sicca 10 | 891
progressive supranuclear palsy 10 | 676
Parkinson's disease 9 | 392
Short stature 9 | 531
cutaneous lupus erythematosus 9 | 1,057
nasopharyngeal carcinoma 9 | 1,058
pediatric high grade glioma 9 | 1,064
sonic hedgehog group medulloblastoma 9 | 467
Becker muscular dystrophy 8 | 191
Epilepsy 8 | 792
Muscle hypotonia 8 | 571
Neurodegenerative disease 8 | 414
active Crohn's disease 8 | 922
limb girdle muscular dystrophy 2A 8 | 213
primary Sjogren syndrome 8 | 735
Bipolar Disorder 7 | 666
Depressive disorder 7 | 409
Intellectual disability 7 | 1,016
Neuropathy 7 | 261
Obesity 7 | 678
Waldenstrons macroglobulinemia 7 | 765
atypical teratoid/rhabdoid tumor 7 | 357
spina bifida 7 | 1,074
Amyotrophic lateral sclerosis 6 | 451
Endometriosis 6 | 540
Mammary Neoplasms, Experimental 6 | 154
Mental Depression 6 | 333
Polycystic ovary syndrome 6 | 360
Prostatic Neoplasms 6 | 495
esophageal adenocarcinoma 6 | 737
hepatocellular carcinoma 6 | 547
Attention deficit hyperactivity disorder 5 | 278
Crohn's disease 5 | 321
Lung Neoplasms 5 | 232
Mental and motor retardation 5 | 608
chronic rhinosinusitis 5 | 512
head and neck cancer 5 | 271
medulloblastoma 5 | 720
urothelial carcinoma 5 | 318

Tissue

Endocrine System 182 | 18,159
Digestive Tract 181 | 17,369
Female tissues 180 | 17,400
Nervous System 180 | 16,725
Liver and Pancreas 179 | 16,750
Male tissues 179 | 17,142
Skin and soft tissues 179 | 17,230
Urinary Tract 178 | 16,678
Blood and immune system 177 | 16,909
Respiratory system 176 | 16,393
Cardiovascular System 171 | 15,192

Target Family

Non-IDG 121 | 12,091
Enzyme 27 | 4,145
Transcription Factor 13 | 1,400
Epigenetic 7 | 242
Kinase 6 | 634
Transporter 5 | 473
GPCR 2 | 408
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Peripheral nervous system 184 | 184
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
SAFB-like transcription modulator SLTM Tdark Non-IDG -0.51977 2.83 111
Zinc finger protein 839 ZNF839 Tdark Non-IDG 0.00000 55
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Zinc finger protein 608 ZNF608 Tdark Non-IDG -0.47998 2.60 62
Protein FAM133B FAM133B Tdark Non-IDG 0.40 0.38 26
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Protein SDA1 homolog SDAD1 Tdark Non-IDG -0.10834 1.45 27
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Ribosome maturation protein SBDS SBDS Tbio Non-IDG -2.24233 174.4 139