Development Level

Tbio 107 | 11,445
Tchem 11 | 1,598
Tclin 10 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 3 | 239
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal placement of pupils 1 | 6
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased spleen weight 1 | 10
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

psoriasis 82 | 6,694
Cancer 72 | 2,499
Carcinoma 64 | 11,493
Rheumatoid arthritis 54 | 1,191
diabetes mellitus 54 | 1,728
ovarian cancer 52 | 8,520
lung cancer 47 | 4,740
Hypersensitivity reaction type II disease 46 | 253
osteosarcoma 45 | 7,950
Arthritis 42 | 290
Juvenile rheumatoid arthritis 41 | 111
dermatomyositis 41 | 966
Psoriatic arthritis 40 | 86
Dermatitis 39 | 157
Acquired immunodeficiency syndrome 38 | 197
Ankylosing spondylitis 37 | 140
Congenital adrenal hyperplasia 37 | 73
Synovitis 37 | 78
glioblastoma 37 | 5,792
Human immunodeficiency virus infectious disease 36 | 138
Stevens-Johnson syndrome 36 | 92
Uveitis 36 | 103
Behcet's disease 35 | 89
Behcet's syndrome 35 | 50
Herpes zoster 35 | 68
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
medulloblastoma, large-cell 34 | 6,241
tuberculosis 33 | 2,010
atypical teratoid / rhabdoid tumor 30 | 5,112
lung carcinoma 29 | 2,843
invasive ductal carcinoma 27 | 2,951
Breast cancer 26 | 3,578
ependymoma 26 | 4,679
non-small cell lung cancer 26 | 2,890
interstitial cystitis 25 | 2,312
pancreatic cancer 25 | 2,398
Astrocytoma, Pilocytic 24 | 3,081
malignant mesothelioma 24 | 3,232
adult high grade glioma 23 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
subependymal giant cell astrocytoma 23 | 2,287
ulcerative colitis 22 | 1,819
lung adenocarcinoma 21 | 2,716
group 3 medulloblastoma 19 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
pituitary cancer 17 | 1,972
Schizophrenia 16 | 1,160
cystic fibrosis 16 | 1,696
colon cancer 15 | 1,478
ductal carcinoma in situ 15 | 1,745
primary Sjogren syndrome 15 | 735
primitive neuroectodermal tumor 15 | 3,035
adrenocortical carcinoma 14 | 1,428
oligodendroglioma 13 | 2,850
primary pancreatic ductal adenocarcinoma 13 | 1,109
Asthma 12 | 385
Autosomal recessive predisposition 12 | 1,442
Kidney cancer 12 | 2,613
astrocytic glioma 12 | 2,597
breast carcinoma 12 | 1,638
astrocytoma 11 | 1,146
group 4 medulloblastoma 11 | 1,855
pediatric high grade glioma 11 | 1,064
acute quadriplegic myopathy 10 | 1,158
cutaneous lupus erythematosus 10 | 1,057
Anemia 9 | 365
Down syndrome 9 | 499
Endometriosis 9 | 540
Multiple Sclerosis 9 | 540
active Crohn's disease 9 | 922
gastric carcinoma 9 | 807
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
periodontitis 9 | 293
sarcoidosis 9 | 370
Atopic dermatitis 8 | 952
Breast Neoplasms 8 | 445
Hypertension 8 | 396
Kidney disease 8 | 430
Liver disease 8 | 237
Mammary Neoplasms 8 | 425
Multiple myeloma 8 | 1,332
Pick disease 8 | 1,894
Prostatic Neoplasms 8 | 495
Thrombocytopenia 8 | 197
Arthritis, Rheumatoid 7 | 174
Bipolar Disorder 7 | 666
Liver Cirrhosis, Experimental 7 | 769
Obesity 7 | 678
Renal Cell Carcinoma 7 | 214
juvenile dermatomyositis 7 | 1,187
mucosa-associated lymphoid tissue lymphoma 7 | 484
Duchenne muscular dystrophy 6 | 601
aldosterone-producing adenoma 6 | 665
hepatocellular carcinoma 6 | 547
spina bifida 6 | 1,074

Tissue

Digestive Tract 94 | 17,369
Endocrine System 93 | 18,159
Liver and Pancreas 92 | 16,750
Male tissues 92 | 17,142
Skin and soft tissues 92 | 17,230
Blood and immune system 91 | 16,909
Female tissues 91 | 17,400
Urinary Tract 91 | 16,678
Respiratory system 90 | 16,393
Nervous System 86 | 16,725
Cardiovascular System 83 | 15,192

Target Family

Non-IDG 99 | 12,091
Enzyme 22 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Ion Channel 1 | 344
Transporter 1 | 473

Jensen-KB Tissue

Peripheral blood 134 | 134
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
Putative inactive carboxylesterase 4 CES1P1 Tbio Enzyme -2.62475 722.3 0
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Splicing factor 3B subunit 2 SF3B2 Tbio Non-IDG -1.32229 20.7 163
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Mitochondrial import inner membrane translocase subunit TIM16 PAM16 Tbio Enzyme -2.36396 227.6 45
Aminopeptidase N ANPEP Tchem Enzyme -3.28127 1843.4 1222
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC Tbio Enzyme -2.73791 419.9 129