Development Level

Tbio 35 | 11,178
Tdark 8 | 6,569
Tchem 4 | 1,885
Tclin 3 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal heart morphology 2 | 162
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
eye hemorrhage 1 | 1
hypoactivity 1 | 132
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 33 | 11,192
ovarian cancer 25 | 8,297
osteosarcoma 21 | 7,766
psoriasis 18 | 6,514
Breast cancer 14 | 3,469
lung cancer 13 | 4,607
medulloblastoma, large-cell 12 | 6,086
invasive ductal carcinoma 11 | 2,867
malignant mesothelioma 11 | 3,135
Autosomal recessive predisposition 10 | 1,407
atypical teratoid / rhabdoid tumor 10 | 4,971
glioblastoma 10 | 5,635
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,872
cystic fibrosis 8 | 1,629
group 3 medulloblastoma 8 | 4,002
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
lung adenocarcinoma 8 | 2,627
lung carcinoma 8 | 2,755
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
Epilepsy 7 | 775
ductal carcinoma in situ 7 | 1,686
ependymoma 7 | 4,559
Astrocytoma, Pilocytic 6 | 3,006
Cognitive delay 6 | 596
Global developmental delay 6 | 596
Mental and motor retardation 6 | 596
Multiple myeloma 6 | 1,296
Seizures 6 | 584
acute quadriplegic myopathy 6 | 1,133
adrenocortical carcinoma 6 | 1,385
astrocytic glioma 6 | 2,530
breast carcinoma 6 | 1,589
colon cancer 6 | 1,428
oligodendroglioma 6 | 2,768
pancreatic cancer 6 | 2,322
ulcerative colitis 6 | 1,765
Kidney cancer 5 | 2,548
Liver Cirrhosis, Experimental 5 | 733
Muscle hypotonia 5 | 562
Pick disease 5 | 1,856
adult high grade glioma 5 | 3,701
diabetes mellitus 5 | 1,683
interstitial cystitis 5 | 2,237
non diabetic and post-ischemic heart failure 5 | 195
pituitary cancer 5 | 1,915
subependymal giant cell astrocytoma 5 | 2,230
Cancer 4 | 2,388
Chronic Lymphocytic Leukemia 4 | 254
Myopathy 4 | 185
Prenatal onset 4 | 137
Waldenstrons macroglobulinemia 4 | 742
astrocytoma 4 | 1,113
primitive neuroectodermal tumor 4 | 2,957
tuberculosis 4 | 1,963
type II diabetes mellitus and post-ischemic heart failure 4 | 85
Asthma 3 | 370
Cerebellar Ataxia 3 | 302
Deglutition Disorders 3 | 128
Highly variable severity 3 | 149
Infantile onset 3 | 236
Lethargy 3 | 77
Muscle Weakness 3 | 168
Obesity 3 | 655
Optic Atrophy 3 | 239
Variable expressivity 3 | 149
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 492
dermatomyositis 3 | 941
fibroadenoma 3 | 538
non-small cell lung cancer 3 | 2,799
progressive supranuclear palsy 3 | 656
spina bifida 3 | 1,053
Byzanthine arch palate 2 | 194
Carcinoma, Hepatocellular 2 | 217
Cerebral atrophy 2 | 175
Creatine phosphokinase serum increased 2 | 110
Disease of mental health 2 | 36
Duchenne muscular dystrophy 2 | 587
Elevated creatine kinase 2 | 110
Failure to gain weight 2 | 359
Heart disease 2 | 288
Hypertension 2 | 372
Hypoglycemia 2 | 146
Kidney disease 2 | 411
Lactic acidosis 2 | 51
Liver carcinoma 2 | 229
Neurodegenerative disease 2 | 402
Neuropathy 2 | 254
Pediatric failure to thrive 2 | 359
Schizophrenia 2 | 1,136
Vomiting 2 | 116
esophageal adenocarcinoma 2 | 696
hepatocellular carcinoma 2 | 536
juvenile dermatomyositis 2 | 1,147
medulloblastoma 2 | 702
mucosa-associated lymphoid tissue lymphoma 2 | 473
nephrosclerosis 2 | 314
pediatric high grade glioma 2 | 1,035
primary pancreatic ductal adenocarcinoma 2 | 1,071
sonic hedgehog group medulloblastoma 2 | 459

Tissue

Endocrine System 49 | 18,159
Skin and soft tissues 49 | 17,230
Cardiovascular System 48 | 15,192
Digestive Tract 48 | 17,369
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Blood and immune system 46 | 16,909
Nervous System 46 | 16,725
Urinary Tract 46 | 16,678
Respiratory system 45 | 16,393

Target Family

Non-IDG 30 | 12,091
Enzyme 13 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

Jensen-KB Tissue

Pericardium 50 | 50
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151
Basic leucine zipper transcriptional factor ATF-like 2 BATF2 Tbio Transcription Factor -2.13891 141.2 148
REST corepressor 3 RCOR3 Tdark Transcription Factor -0.34593 1.72 65
Myotilin MYOT Tbio Non-IDG -1.90038 80.3 177
Ras GTPase-activating protein-binding protein 1 G3BP1 Tbio Enzyme -2.01627 111.4 426
Calsequestrin-1 CASQ1 Tbio Non-IDG -1.96476 86.8 103
WD repeat-containing protein 41 WDR41 Tbio Non-IDG -0.28817 1.20 77
Carbonic anhydrase 3 CA3 Tclin Enzyme -2.88504 757.4 287
UDP-glucuronosyltransferase 2B4 UGT2B4 Tbio Enzyme -1.58066 34.6 140
Zinc finger CCHC domain-containing protein 9 ZCCHC9 Tdark Non-IDG 0.48 0.71 31