Development Level

Tbio 28 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal vibrissa morphology 1 | 25
cleft palate 1 | 8
corneal opacity 1 | 32
cyanosis 1 | 7
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased pulmonary respirator... 1 | 5
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
vertebral transformation 1 | 12

Disease

Carcinoma 21 | 11,493
glioblastoma 19 | 5,792
ovarian cancer 18 | 8,520
osteosarcoma 16 | 7,950
psoriasis 16 | 6,694
ependymoma 15 | 4,679
lung cancer 15 | 4,740
Cancer 14 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
medulloblastoma, large-cell 14 | 6,241
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
pancreatic cancer 12 | 2,398
lung adenocarcinoma 11 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 10 | 2,951
Breast cancer 9 | 3,578
astrocytic glioma 9 | 2,597
malignant mesothelioma 9 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
primitive neuroectodermal tumor 9 | 3,035
ductal carcinoma in situ 8 | 1,745
non-small cell lung cancer 8 | 2,890
breast carcinoma 7 | 1,638
nasopharyngeal carcinoma 7 | 1,058
oligodendroglioma 7 | 2,850
Astrocytoma, Pilocytic 6 | 3,081
Atopic dermatitis 6 | 952
colon cancer 6 | 1,478
lung carcinoma 6 | 2,843
Adenoma 5 | 167
Stomach Neoplasms 5 | 300
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
Anemia 4 | 365
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Diarrhea 4 | 253
Kidney cancer 4 | 2,613
Mammary Neoplasms 4 | 425
Mesothelioma, Malignant 4 | 105
Pick disease 4 | 1,894
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
tuberculosis 4 | 2,010
Down syndrome 3 | 499
Downward slant of palpebral fissure 3 | 158
Endometriosis 3 | 540
Epilepsy 3 | 792
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Orbital separation excessive 3 | 244
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
non-small cell lung carcinoma 3 | 317
pancreatic carcinoma 3 | 562
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Bipolar Disorder 2 | 666
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Dysarthria 2 | 192
Endometrial cancer 2 | 311
Frontal bossing 2 | 157
Hemoglobin low 2 | 124
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Parkinson's disease 2 | 392
Pilocytic astrocytoma 2 | 56
Urinary Bladder Neoplasms 2 | 114
acute quadriplegic myopathy 2 | 1,158
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Digestive Tract 34 | 17,369
Male tissues 34 | 17,142
Blood and immune system 33 | 16,909
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Skin and soft tissues 33 | 17,230
Endocrine System 32 | 18,159
Nervous System 32 | 16,725
Urinary Tract 32 | 16,678
Respiratory system 31 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 11 | 4,145
GPCR 2 | 408
Transcription Factor 2 | 1,400
Transporter 1 | 473

Jensen-KB Tissue

Pancreatic cancer cell line 34 | 34
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
ATP-binding cassette sub-family A member 10 ABCA10 Tdark Transporter -0.25772 2.27 36
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Oral cancer-overexpressed protein 1 ORAOV1 Tbio Non-IDG -1.06859 14.3 41
Mesothelin MSLN Tbio Non-IDG -2.66061 452.1 542
Heterogeneous nuclear ribonucleoprotein L HNRNPL Tbio Non-IDG -2.53786 319.0 271
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Golgin subfamily A member 3 GOLGA3 Tbio Non-IDG -1.33499 21.1 140
Mucin-4 MUC4 Tbio Non-IDG -2.57857 403.3 234
4-hydroxybenzoate polyprenyltransferase, mitochondrial COQ2 Tbio Enzyme -2.13154 132.2 47