Development Level

Tbio 138 | 10,625
Tchem 20 | 1,890
Tdark 19 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 10 | 633
embryonic lethality prior to t... 5 | 187
abnormal embryo size 4 | 112
decreased circulating calcium ... 4 | 33
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
decreased fasted circulating g... 3 | 49
enlarged heart 3 | 111
increased heart weight 3 | 37
increased or absent threshold ... 3 | 128
abnormal vertebrae morphology 2 | 14
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased lean body mass 2 | 195
decreased total retina thickne... 2 | 20
increased body weight 2 | 42
increased circulating chloride... 2 | 43
increased lean body mass 2 | 107
abnormal bone structure 1 | 131
abnormal embryo turning 1 | 15
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 6
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
enlarged heart atrium 1 | 2
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
increased circulating alkaline... 1 | 119
increased circulating creatini... 1 | 29
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
prolonged PQ interval 1 | 3
short tibia 1 | 82
small thymus 1 | 11
tremors 1 | 34

Disease

ovarian cancer 119 | 8,484
osteosarcoma 101 | 7,933
psoriasis 75 | 6,685
medulloblastoma, large-cell 72 | 6,234
glioblastoma 62 | 5,572
lung cancer 62 | 4,466
Breast cancer 51 | 3,094
malignant mesothelioma 48 | 3,162
Multiple myeloma 41 | 1,327
atypical teratoid / rhabdoid tumor 41 | 4,369
ependymoma 41 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,988
oligodendroglioma 38 | 2,849
primitive neuroectodermal tumor 37 | 3,031
acute quadriplegic myopathy 36 | 1,157
Cancer 35 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,289
pancreatic cancer 35 | 2,300
invasive ductal carcinoma 34 | 2,950
pediatric high grade glioma 33 | 2,712
non-small cell lung cancer 32 | 2,798
group 3 medulloblastoma 31 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,956
pilocytic astrocytoma 29 | 3,086
lung adenocarcinoma 28 | 2,713
Pick disease 27 | 1,893
Waldenstrons macroglobulinemia 27 | 765
subependymal giant cell astrocytoma 26 | 2,287
astrocytoma 25 | 1,493
breast carcinoma 25 | 1,614
group 4 medulloblastoma 25 | 1,875
astrocytic glioma 24 | 2,241
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
dermatomyositis 22 | 933
atypical teratoid/rhabdoid tumor 21 | 1,095
Carcinoma 20 | 2,147
cystic fibrosis 20 | 1,665
interstitial cystitis 20 | 2,299
lung carcinoma 20 | 2,844
primary pancreatic ductal adenocarcinoma 20 | 1,271
juvenile dermatomyositis 19 | 1,189
sonic hedgehog group medulloblastoma 19 | 1,482
adult high grade glioma 17 | 2,148
diabetes mellitus 17 | 1,663
ulcerative colitis 17 | 2,087
Amyotrophic Lateral Sclerosis 16 | 431
adrenocortical carcinoma 16 | 1,427
nasopharyngeal carcinoma 16 | 1,056
acute myeloid leukemia 15 | 780
colon cancer 14 | 1,475
medulloblastoma 14 | 1,524
pituitary cancer 14 | 1,972
posterior fossa group A ependymoma 14 | 1,511
cutaneous lupus erythematosus 13 | 1,056
progressive supranuclear palsy 13 | 674
gastric carcinoma 12 | 832
Atopic dermatitis 11 | 944
Mammary Neoplasms 11 | 410
ductal carcinoma in situ 11 | 1,745
spina bifida 11 | 1,064
active Crohn's disease 10 | 918
aldosterone-producing adenoma 10 | 664
gastric cancer 10 | 430
posterior fossa group B ependymoma 10 | 1,530
primary Sjogren syndrome 10 | 789
tuberculosis 10 | 1,557
tuberculosis and treatment for 6 months 10 | 686
Intellectual disability 9 | 573
Rheumatoid Arthritis 9 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
hepatocellular carcinoma 9 | 532
non primary Sjogren syndrome sicca 9 | 840
pancreatic carcinoma 9 | 567
Stomach Neoplasms 8 | 282
esophageal adenocarcinoma 8 | 737
inflammatory breast cancer 8 | 404
non-small cell lung carcinoma 8 | 413
Duchenne muscular dystrophy 7 | 602
Gaucher disease type 1 7 | 171
Craniofacial Abnormalities 6 | 147
Disease Progression 6 | 125
Down syndrome 6 | 548
Endometriosis 6 | 535
IGA Glomerulonephritis 6 | 454
Polycystic Ovary Syndrome 6 | 332
Prostatic Neoplasms 6 | 471
interstitial lung disease 6 | 291
mucosa-associated lymphoid tissue lymphoma 6 | 480
tuberculosis and treatment for 3 months 6 | 327
Alzheimer's disease 5 | 644
Cerebrovascular disease 5 | 231
Frontotemporal dementia 5 | 41
HIV Infections 5 | 100
Neurodegenerative disease 5 | 383
Obesity 5 | 616
Treacher Collins syndrome 5 | 29
active ulcerative colitis 5 | 477
cystic fibrosis and chronic rhinosinusitis 5 | 213
Asthma 4 | 349
fibroadenoma 4 | 557

Tissue

Blood and immune system 180 | 17,995
Cardiovascular System 180 | 17,958
Digestive Tract 180 | 18,473
Endocrine System 180 | 18,512
Female tissues 180 | 18,647
Liver and Pancreas 180 | 18,136
Male tissues 180 | 17,969
Nervous System 180 | 18,561
Respiratory system 180 | 17,484
Urinary Tract 180 | 18,444
Skin and soft tissues 178 | 18,115

Target Family

Non-IDG 126 | 11,971
Enzyme 39 | 4,146
Transcription Factor 7 | 1,400
GPCR 3 | 406
Transporter 3 | 473
Epigenetic 2 | 242
Ion Channel 1 | 341

Jensen-KB Tissue

Ovary cancer cell 181 | 181
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Apoptosis inhibitor 5 API5 Tbio Non-IDG -1.32754 23.5 171
Signal recognition particle 9 kDa protein SRP9 Tbio Non-IDG -1.49375 30.2 29
Trinucleotide repeat-containing gene 6A protein TNRC6A Tbio Non-IDG -2.03159 112.3 66
Transformer-2 protein homolog beta TRA2B Tbio Non-IDG -1.57359 39.3 112
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.81595 662.3 551
Keratin, type I cytoskeletal 13 KRT13 Tbio Non-IDG -2.21878 161.7 349
Heterogeneous nuclear ribonucleoprotein A3 HNRNPA3 Tbio Non-IDG -1.33686 20.5 81