Development Level

Tbio 436 | 10,625
Tdark 166 | 7,003
Tchem 66 | 1,890
Tclin 22 | 602

Collection

Eligible Kinase Proteins 6 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 23 | 633
abnormal behavior 11 | 226
embryonic lethality prior to t... 11 | 187
decreased circulating triglyce... 10 | 83
decreased bone mineral density 9 | 126
decreased lean body mass 9 | 195
preweaning lethality, incomple... 9 | 260
hyperactivity 8 | 108
decreased bone mineral content 7 | 157
embryonic lethality prior to o... 7 | 148
abnormal embryo size 6 | 112
decreased body weight 6 | 174
abnormal lens morphology 5 | 73
abnormal neural tube closure 5 | 37
decreased circulating glucose ... 5 | 121
decreased startle reflex 5 | 48
improved glucose tolerance 5 | 56
increased mean corpuscular hem... 5 | 93
increased or absent threshold ... 5 | 128
abnormal heart morphology 4 | 51
decreased body length 4 | 108
enlarged heart 4 | 111
impaired glucose tolerance 4 | 52
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
decreased grip strength 3 | 123
decreased monocyte cell number 3 | 28
decreased prepulse inhibition 3 | 52
decreased rib number 3 | 59
decreased total body fat amoun... 3 | 186
embryonic growth retardation 3 | 28
increased body weight 3 | 42
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased grip strength 3 | 83
increased lean body mass 3 | 107
increased mean corpuscular vol... 3 | 91
pallor 3 | 13
abnormal bone mineralization 2 | 55
abnormal cornea morphology 2 | 24
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 18
abnormal kidney morphology 2 | 30
abnormal limb bud morphology 2 | 15
abnormal locomotor activation 2 | 26
abnormal retina morphology 2 | 100
abnormal seminal vesicle morph... 2 | 47
abnormal skin appearance 2 | 8
abnormal spleen morphology 2 | 36
abnormal tail bud morphology 2 | 6
abnormal vocalization 2 | 21
cardiovascular system phenotyp... 2 | 35
decreased CD4-positive, alpha ... 2 | 19
decreased Ly6C high monocyte n... 2 | 18
decreased T cell number 2 | 31
decreased caudal vertebrae num... 2 | 49
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased neutrophil cell numb... 2 | 37
decreased thoracic vertebrae n... 2 | 7
decreased threshold for audito... 2 | 32
enlarged spleen 2 | 26
female infertility 2 | 34
hydrometra 2 | 13
hypoactivity 2 | 89
increased B cell number 2 | 23
increased NK cell number 2 | 19
increased body length 2 | 20
increased circulating aspartat... 2 | 17
increased circulating choleste... 2 | 53
increased circulating glucose ... 2 | 16
increased circulating iron lev... 2 | 25
increased circulating sodium l... 2 | 71
increased exploration in new e... 2 | 56
increased heart rate 2 | 17
increased leukocyte cell numbe... 2 | 37
increased sacral vertebrae num... 2 | 62
increased startle reflex 2 | 38
increased total body fat amoun... 2 | 57
prenatal lethality 2 | 16
shortened RR interval 2 | 19
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal embryo turning 1 | 15
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
decreased circulating chloride... 1 | 32
decreased eosinophil cell numb... 1 | 41
impaired righting response 1 | 19
increased bone mineral density 1 | 52
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 394 | 8,484
osteosarcoma 325 | 7,933
psoriasis 245 | 6,685
medulloblastoma, large-cell 240 | 6,234
glioblastoma 219 | 5,572
lung cancer 192 | 4,466
atypical teratoid / rhabdoid tumor 173 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 150 | 3,289
invasive ductal carcinoma 143 | 2,950
malignant mesothelioma 142 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 130 | 2,988
Breast cancer 129 | 3,094
non-small cell lung cancer 125 | 2,798
lung adenocarcinoma 124 | 2,713
pediatric high grade glioma 121 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 118 | 2,956
oligodendroglioma 118 | 2,849
pancreatic cancer 116 | 2,300
primitive neuroectodermal tumor 114 | 3,031
pilocytic astrocytoma 113 | 3,086
ependymoma 99 | 2,514
Cancer 97 | 2,346
ductal carcinoma in situ 87 | 1,745
lung carcinoma 87 | 2,844
subependymal giant cell astrocytoma 85 | 2,287
interstitial cystitis 84 | 2,299
astrocytic glioma 83 | 2,241
breast carcinoma 81 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 78 | 1,795
group 3 medulloblastoma 76 | 2,254
pituitary cancer 75 | 1,972
cystic fibrosis 73 | 1,665
adult high grade glioma 72 | 2,148
sonic hedgehog group medulloblastoma 72 | 1,482
Pick disease 71 | 1,893
posterior fossa group A ependymoma 71 | 1,511
Multiple myeloma 70 | 1,327
diabetes mellitus 70 | 1,663
ulcerative colitis 70 | 2,087
group 4 medulloblastoma 69 | 1,875
astrocytoma 67 | 1,493
primary pancreatic ductal adenocarcinoma 65 | 1,271
medulloblastoma 64 | 1,524
tuberculosis 63 | 1,557
colon cancer 58 | 1,475
posterior fossa group B ependymoma 53 | 1,530
Rheumatoid Arthritis 52 | 1,160
acute quadriplegic myopathy 51 | 1,157
Carcinoma 47 | 2,147
adrenocortical carcinoma 45 | 1,427
cutaneous lupus erythematosus 44 | 1,056
juvenile dermatomyositis 42 | 1,189
gastric carcinoma 41 | 832
Atopic dermatitis 39 | 944
esophageal adenocarcinoma 39 | 737
nasopharyngeal carcinoma 38 | 1,056
non primary Sjogren syndrome sicca 37 | 840
spina bifida 37 | 1,064
Duchenne muscular dystrophy 35 | 602
fibroadenoma 34 | 557
Waldenstrons macroglobulinemia 33 | 765
dermatomyositis 33 | 933
Alzheimer's disease 31 | 644
atypical teratoid/rhabdoid tumor 31 | 1,095
Down syndrome 29 | 548
aldosterone-producing adenoma 29 | 664
active Crohn's disease 27 | 918
acute myeloid leukemia 27 | 780
Prostatic Neoplasms 24 | 471
pancreatic carcinoma 23 | 567
Intellectual disability 22 | 573
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
inflammatory breast cancer 22 | 404
Endometriosis 21 | 535
progressive supranuclear palsy 21 | 674
tuberculosis and treatment for 6 months 21 | 686
Mammary Neoplasms 20 | 410
Neurodegenerative disease 20 | 383
IGA Glomerulonephritis 19 | 454
chronic rhinosinusitis 19 | 512
interstitial lung disease 19 | 291
Mammary Neoplasms, Experimental 18 | 150
Amyotrophic Lateral Sclerosis 17 | 431
Polycystic Ovary Syndrome 17 | 332
Vascular disease 17 | 281
mucosa-associated lymphoid tissue lymphoma 17 | 480
Animal Mammary Neoplasms 16 | 136
Kidney disease 16 | 396
nephrosclerosis 16 | 329
tuberculosis and treatment for 3 months 16 | 327
Obesity 15 | 616
Osteoporosis 15 | 257
hepatocellular carcinoma 15 | 532
Barrett's esophagus 14 | 183
Epilepsy 14 | 346
glioblastoma multiforme 14 | 347
primary Sjogren syndrome 14 | 789
Heart disease 13 | 279
Schizophrenia 13 | 501
gastric cancer 13 | 430

Tissue

Female tissues 679 | 18,647
Liver and Pancreas 678 | 18,136
Nervous System 678 | 18,561
Urinary Tract 678 | 18,444
Cardiovascular System 677 | 17,958
Digestive Tract 677 | 18,473
Endocrine System 677 | 18,512
Blood and immune system 676 | 17,995
Male tissues 675 | 17,969
Skin and soft tissues 674 | 18,115
Respiratory system 671 | 17,484

Target Family

Non-IDG 402 | 11,971
Enzyme 178 | 4,146
Transcription Factor 44 | 1,400
Kinase 22 | 634
Transporter 16 | 473
GPCR 11 | 406
Ion Channel 7 | 341
Epigenetic 6 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Ovary 690 | 690
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
Protein BEX3 BEX3 Tbio Non-IDG -1.87293 81.4 184
Oligodendrocyte transcription factor 3 OLIG3 Tbio Transcription Factor -0.81946 6.73 131
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Interleukin-1 receptor type 2 IL1R2 Tbio Non-IDG -1.85724 72.1 361