Development Level

Tbio 127 | 11,651
Tdark 42 | 6,593
Tchem 11 | 1,388
Tclin 7 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 18 | 979
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
decreased bone mineral content 4 | 151
embryonic lethality prior to o... 4 | 239
hyperactivity 4 | 148
abnormal retina morphology 3 | 71
decreased lean body mass 3 | 135
decreased red blood cell distr... 3 | 41
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
hypoactivity 3 | 132
small superior vagus ganglion 3 | 74
abnormal behavioral response t... 2 | 66
abnormal facial morphology 2 | 17
abnormal lens morphology 2 | 81
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cyanosis 2 | 7
decreased circulating choleste... 2 | 93
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal iris pigmentation 1 | 4
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal optic disc morphology 1 | 10
abnormal outer ear morphology 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent spleen 1 | 3
brachydactyly 1 | 19
cleft palate 1 | 8
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
male infertility 1 | 123
pale yolk sac 1 | 25
short tibia 1 | 97
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 108 | 11,493
ovarian cancer 92 | 8,520
osteosarcoma 85 | 7,950
medulloblastoma, large-cell 73 | 6,241
glioblastoma 69 | 5,792
group 3 medulloblastoma 69 | 4,104
atypical teratoid / rhabdoid tumor 62 | 5,112
psoriasis 62 | 6,694
ependymoma 58 | 4,679
primitive neuroectodermal tumor 46 | 3,035
lung cancer 45 | 4,740
adult high grade glioma 43 | 3,801
Astrocytoma, Pilocytic 41 | 3,081
malignant mesothelioma 39 | 3,232
astrocytic glioma 37 | 2,597
Breast cancer 36 | 3,578
oligodendroglioma 36 | 2,850
subependymal giant cell astrocytoma 36 | 2,287
invasive ductal carcinoma 35 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
Pick disease 28 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
lung adenocarcinoma 26 | 2,716
Kidney cancer 25 | 2,613
non-small cell lung cancer 24 | 2,890
Cancer 23 | 2,499
lung carcinoma 23 | 2,843
ulcerative colitis 22 | 1,819
diabetes mellitus 21 | 1,728
adrenocortical carcinoma 20 | 1,428
interstitial cystitis 20 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Multiple myeloma 19 | 1,332
ductal carcinoma in situ 19 | 1,745
pancreatic cancer 19 | 2,398
Intellectual disability 18 | 1,016
breast carcinoma 18 | 1,638
tuberculosis 18 | 2,010
colon cancer 17 | 1,478
group 4 medulloblastoma 17 | 1,855
pituitary cancer 17 | 1,972
Autosomal recessive predisposition 13 | 1,442
acute myeloid leukemia 13 | 783
juvenile dermatomyositis 13 | 1,187
acute quadriplegic myopathy 12 | 1,158
astrocytoma 12 | 1,146
Waldenstrons macroglobulinemia 11 | 765
cutaneous lupus erythematosus 11 | 1,057
dermatomyositis 11 | 966
pediatric high grade glioma 11 | 1,064
progressive supranuclear palsy 11 | 676
Dull intelligence 10 | 645
Epilepsy 10 | 792
Liver cancer 10 | 604
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
primary pancreatic ductal adenocarcinoma 10 | 1,109
Atopic dermatitis 9 | 952
Bipolar Disorder 9 | 666
Liver Cirrhosis, Experimental 9 | 769
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
Muscle hypotonia 8 | 571
Parkinson's disease 8 | 392
Stomach Neoplasms 8 | 300
aldosterone-producing adenoma 8 | 665
atypical teratoid/rhabdoid tumor 8 | 357
cystic fibrosis 8 | 1,696
nasopharyngeal carcinoma 8 | 1,058
Cognitive delay 7 | 608
Crohn's disease 7 | 321
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Seizures 7 | 596
active Crohn's disease 7 | 922
spina bifida 7 | 1,074
Anemia 6 | 365
Down syndrome 6 | 499
Multiple Sclerosis 6 | 540
active ulcerative colitis 6 | 764
non primary Sjogren syndrome sicca 6 | 891
Alzheimer's disease 5 | 658
Cerebral atrophy 5 | 178
Cleft Palate 5 | 271
Colorectal Neoplasms 5 | 243
Duchenne muscular dystrophy 5 | 601
Hypertension 5 | 396
Melanoma 5 | 711
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
Obesity 5 | 678
Optic Atrophy 5 | 242
hepatocellular carcinoma 5 | 547
medulloblastoma 5 | 720
posterior fossa group B ependymoma 5 | 416
sonic hedgehog group medulloblastoma 5 | 467
urothelial carcinoma 5 | 318

Tissue

Endocrine System 183 | 18,159
Digestive Tract 181 | 17,369
Nervous System 181 | 16,725
Female tissues 179 | 17,400
Liver and Pancreas 179 | 16,750
Skin and soft tissues 179 | 17,230
Male tissues 178 | 17,142
Urinary Tract 177 | 16,678
Blood and immune system 175 | 16,909
Respiratory system 174 | 16,393
Cardiovascular System 173 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 38 | 4,145
Transcription Factor 15 | 1,400
Kinase 7 | 634
Ion Channel 4 | 344
Transporter 4 | 473
Epigenetic 2 | 242

Jensen-KB Tissue

Neuroblastoma cell 187 | 187
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RBPJ-interacting and tubulin-associated protein 1 RITA1 Tbio Non-IDG -0.85891 6.79 61
Oxidation resistance protein 1 OXR1 Tbio Non-IDG -1.67505 49.4 144
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.22337 16.5 217
E3 ubiquitin-protein ligase CBL-B CBLB Tbio Enzyme -0.82313 6.58 193
ADP-ribosylation factor GTPase-activating protein 2 ARFGAP2 Tbio Enzyme -0.97596 10.1 144
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Testis-expressed protein 10 TEX10 Tdark Non-IDG -0.59960 4.28 21
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D Tclin Ion Channel -2.43448 273.2 215
Alanyl-tRNA editing protein Aarsd1 AARSD1 Tdark Non-IDG 0.60 0.20 53
Microsomal glutathione S-transferase 2 MGST2 Tbio Enzyme -1.15686 13.6 120