Development Level

Tbio 113 | 10,625
Tdark 50 | 7,003
Tchem 18 | 1,890
Tclin 6 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 11 | 633
decreased total body fat amoun... 4 | 186
hyperactivity 4 | 108
abnormal retina morphology 3 | 100
abnormal retinal pigmentation 3 | 61
abnormal seminal vesicle morph... 3 | 47
abnormal sleep behavior 3 | 63
decreased bone mineral content 3 | 157
embryonic lethality prior to t... 3 | 187
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal embryo size 2 | 112
abnormal facial morphology 2 | 9
cyanosis 2 | 6
decreased body length 2 | 108
decreased erythrocyte cell num... 2 | 43
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 107
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal eye morphology 1 | 38
abnormal head shape 1 | 4
abnormal hindbrain development 1 | 24
abnormal iris pigmentation 1 | 3
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb morphology 1 | 7
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal outer ear morphology 1 | 1
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal spinal cord morpholog... 1 | 8
abnormal testis morphology 1 | 30
cleft palate 1 | 6
convulsive seizures 1 | 11
craniofacial phenotype 1 | 9
decreased B cell number 1 | 30
decreased CD103-positive CD11b... 1 | 2
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased follicular B cell nu... 1 | 4
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased red blood cell distr... 1 | 11
hemorrhage 1 | 12
herniated abdominal wall 1 | 4
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased CD8-positive, naive ... 1 | 3
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
pale yolk sac 1 | 12
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small superior vagus ganglion 1 | 20
small testis 1 | 37
thick ventricular wall 1 | 7
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 91 | 8,484
osteosarcoma 84 | 7,933
medulloblastoma, large-cell 73 | 6,234
glioblastoma 68 | 5,572
psoriasis 61 | 6,685
atypical teratoid / rhabdoid tumor 55 | 4,369
primitive neuroectodermal tumor 46 | 3,031
lung cancer 45 | 4,466
group 3 medulloblastoma 42 | 2,254
pilocytic astrocytoma 41 | 3,086
malignant mesothelioma 38 | 3,162
oligodendroglioma 37 | 2,849
subependymal giant cell astrocytoma 36 | 2,287
invasive ductal carcinoma 35 | 2,950
pediatric high grade glioma 33 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,289
Breast cancer 29 | 3,094
Pick disease 28 | 1,893
astrocytic glioma 28 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
lung adenocarcinoma 26 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
ulcerative colitis 25 | 2,087
ependymoma 23 | 2,514
lung carcinoma 23 | 2,844
adult high grade glioma 22 | 2,148
astrocytoma 22 | 1,493
non-small cell lung cancer 22 | 2,798
posterior fossa group B ependymoma 22 | 1,530
Cancer 21 | 2,346
posterior fossa group A ependymoma 21 | 1,511
Carcinoma 20 | 2,147
adrenocortical carcinoma 20 | 1,427
interstitial cystitis 20 | 2,299
Multiple myeloma 19 | 1,327
diabetes mellitus 19 | 1,663
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
breast carcinoma 18 | 1,614
medulloblastoma 18 | 1,524
pancreatic cancer 18 | 2,300
colon cancer 17 | 1,475
pituitary cancer 17 | 1,972
sonic hedgehog group medulloblastoma 16 | 1,482
atypical teratoid/rhabdoid tumor 15 | 1,095
acute myeloid leukemia 13 | 780
juvenile dermatomyositis 13 | 1,189
tuberculosis 13 | 1,557
Intellectual disability 12 | 573
acute quadriplegic myopathy 12 | 1,157
Waldenstrons macroglobulinemia 11 | 765
cutaneous lupus erythematosus 11 | 1,056
dermatomyositis 11 | 933
primary pancreatic ductal adenocarcinoma 11 | 1,271
Rheumatoid Arthritis 10 | 1,160
progressive supranuclear palsy 10 | 674
Atopic dermatitis 8 | 944
Parkinson's disease 8 | 364
Stomach Neoplasms 8 | 282
aldosterone-producing adenoma 8 | 664
cystic fibrosis 8 | 1,665
nasopharyngeal carcinoma 8 | 1,056
tuberculosis and treatment for 6 months 8 | 686
Down syndrome 7 | 548
active Crohn's disease 7 | 918
spina bifida 7 | 1,064
Crohn's disease 6 | 304
IGA Glomerulonephritis 6 | 454
non primary Sjogren syndrome sicca 6 | 840
Alzheimer's disease 5 | 644
Anemia 5 | 252
Duchenne muscular dystrophy 5 | 602
Epilepsy 5 | 346
Multiple Sclerosis 5 | 498
Neurodegenerative disease 5 | 383
Neuropathy 5 | 210
Obesity 5 | 616
Polydactyly 5 | 93
glioblastoma multiforme 5 | 347
hepatocellular carcinoma 5 | 532
non-inflammatory breast cancer 5 | 208
urothelial carcinoma 5 | 318
Acquired metabolic disease 4 | 267
Amyotrophic Lateral Sclerosis 4 | 431
Autistic Disorder 4 | 320
Colonic Neoplasms 4 | 126
Endometriosis 4 | 535
Neuroblastoma 4 | 78
cystic fibrosis and chronic rhinosinusitis 4 | 213
fibroadenoma 4 | 557
interstitial lung disease 4 | 291
nephrosclerosis 4 | 329
non-small cell lung carcinoma 4 | 413
primary Sjogren syndrome 4 | 789
sarcoidosis 4 | 358
Becker muscular dystrophy 3 | 187
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832

Tissue

Digestive Tract 184 | 18,473
Endocrine System 184 | 18,512
Female tissues 184 | 18,647
Liver and Pancreas 184 | 18,136
Nervous System 184 | 18,561
Cardiovascular System 183 | 17,958
Male tissues 183 | 17,969
Skin and soft tissues 183 | 18,115
Urinary Tract 183 | 18,444
Blood and immune system 182 | 17,995
Respiratory system 182 | 17,484

Target Family

Non-IDG 118 | 11,971
Enzyme 37 | 4,146
Transcription Factor 15 | 1,400
Kinase 7 | 634
Ion Channel 4 | 341
Transporter 4 | 473
Epigenetic 2 | 242

Jensen-KB Tissue

Neuroblastoma cell 187 | 187
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Homeobox protein Hox-D8 HOXD8 Tbio Transcription Factor -1.03632 9.95 167
Mitochondrial ribonuclease P protein 3 KIAA0391 Tbio Enzyme 66.3 56
Ubiquitin-conjugating enzyme E2 variant 3 UEVLD Tdark Non-IDG 0.18 0.85 86
Zinc finger protein 540 ZNF540 Tbio Transcription Factor -0.07979 1.20 70
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Regulator of G-protein signaling 5 RGS5 Tbio Non-IDG -1.60212 47.5 222
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
Nestin NES Tbio Non-IDG -3.33502 2122.7 622
Nuclear receptor coactivator 7 NCOA7 Tbio Non-IDG -0.99962 13.1 109