Development Level

Tbio 496 | 10,625
Tdark 121 | 7,003
Tchem 75 | 1,890
Tclin 29 | 602

Collection

Eligible Kinase Proteins 11 | 134
Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 44 | 633
abnormal behavior 18 | 226
decreased lean body mass 18 | 195
decreased total body fat amoun... 17 | 186
preweaning lethality, incomple... 17 | 260
embryonic lethality prior to t... 16 | 187
abnormal bone structure 13 | 131
decreased body length 13 | 108
increased circulating alkaline... 13 | 119
decreased bone mineral content 11 | 157
abnormal embryo size 10 | 112
decreased body weight 10 | 174
hypoactivity 10 | 89
decreased circulating glucose ... 9 | 121
embryonic lethality prior to o... 9 | 148
increased grip strength 9 | 83
decreased bone mineral density 8 | 126
decreased circulating choleste... 8 | 85
decreased circulating serum al... 8 | 79
hyperactivity 8 | 108
improved glucose tolerance 8 | 56
increased circulating HDL chol... 8 | 63
decreased circulating HDL chol... 7 | 77
increased circulating choleste... 7 | 53
increased or absent threshold ... 7 | 128
abnormal bone mineralization 6 | 55
abnormal retina morphology 6 | 100
abnormal sleep behavior 6 | 63
decreased grip strength 6 | 123
increased lean body mass 6 | 107
increased mean corpuscular hem... 6 | 93
increased mean corpuscular vol... 6 | 91
increased total body fat amoun... 6 | 57
short tibia 6 | 82
abnormal coat/hair pigmentatio... 5 | 54
abnormal eye morphology 5 | 38
abnormal lens morphology 5 | 73
anophthalmia 5 | 20
decreased circulating total pr... 5 | 41
increased circulating calcium ... 5 | 32
increased circulating sodium l... 5 | 71
increased heart weight 5 | 37
abnormal neural tube closure 4 | 37
abnormal retinal pigmentation 4 | 61
decreased CD4-positive, alpha ... 4 | 19
decreased circulating alkaline... 4 | 41
decreased circulating amylase ... 4 | 24
decreased circulating calcium ... 4 | 33
decreased circulating triglyce... 4 | 83
decreased erythrocyte cell num... 4 | 43
decreased hemoglobin content 4 | 53
decreased lumbar vertebrae num... 4 | 62
decreased mean corpuscular vol... 4 | 50
decreased rib number 4 | 59
increased body weight 4 | 42
increased circulating phosphat... 4 | 24
increased circulating serum al... 4 | 25
increased mean platelet volume 4 | 19
increased sacral vertebrae num... 4 | 62
prenatal lethality prior to he... 4 | 64
thrombocytopenia 4 | 46
abnormal cranium morphology 3 | 32
abnormal hindbrain development 3 | 24
abnormal humerus morphology 3 | 11
abnormal midbrain development 3 | 22
abnormal placenta size 3 | 10
abnormal response to tactile s... 3 | 16
abnormal retinal blood vessel ... 3 | 18
abnormal rib morphology 3 | 28
abnormal vertebrae morphology 3 | 14
decreased CD8-positive, alpha-... 3 | 26
decreased T cell number 3 | 31
decreased circulating LDL chol... 3 | 37
decreased circulating insulin ... 3 | 75
decreased heart weight 3 | 44
decreased mean corpuscular hem... 3 | 19
decreased startle reflex 3 | 48
decreased total retina thickne... 3 | 20
embryonic growth retardation 3 | 28
enlarged heart 3 | 111
hydrops fetalis 3 | 22
immune system phenotype 3 | 17
increased bone mineral content 3 | 92
increased circulating creatini... 3 | 29
increased circulating glycerol... 3 | 11
increased circulating potassiu... 3 | 31
increased circulating triglyce... 3 | 24
increased exploration in new e... 3 | 56
male infertility 3 | 62
microphthalmia 3 | 15
pallor 3 | 13
straub tail 3 | 26
vertebral fusion 3 | 23
abnormal gait 2 | 51
decreased fasted circulating g... 2 | 49
impaired glucose tolerance 2 | 52
increased circulating chloride... 2 | 43
increased circulating total pr... 2 | 20
increased fasted circulating g... 2 | 68
thrombocytosis 2 | 23

Disease

ovarian cancer 415 | 8,484
osteosarcoma 331 | 7,933
medulloblastoma, large-cell 282 | 6,234
psoriasis 267 | 6,685
glioblastoma 238 | 5,572
lung cancer 229 | 4,466
atypical teratoid / rhabdoid tumor 203 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 154 | 3,289
malignant mesothelioma 151 | 3,162
Breast cancer 138 | 3,094
invasive ductal carcinoma 136 | 2,950
non-small cell lung cancer 133 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 129 | 2,988
Cancer 120 | 2,346
pediatric high grade glioma 119 | 2,712
primitive neuroectodermal tumor 118 | 3,031
lung adenocarcinoma 117 | 2,713
group 3 medulloblastoma 115 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 114 | 2,956
oligodendroglioma 113 | 2,849
ependymoma 108 | 2,514
Multiple myeloma 104 | 1,327
pancreatic cancer 103 | 2,300
pilocytic astrocytoma 101 | 3,086
pancreatic ductal adenocarcinoma liver metastasis 95 | 1,795
astrocytic glioma 88 | 2,241
ductal carcinoma in situ 83 | 1,745
subependymal giant cell astrocytoma 82 | 2,287
breast carcinoma 81 | 1,614
adult high grade glioma 80 | 2,148
group 4 medulloblastoma 78 | 1,875
Pick disease 77 | 1,893
diabetes mellitus 77 | 1,663
ulcerative colitis 74 | 2,087
colon cancer 71 | 1,475
adrenocortical carcinoma 70 | 1,427
lung carcinoma 70 | 2,844
Carcinoma 68 | 2,147
cystic fibrosis 64 | 1,665
sonic hedgehog group medulloblastoma 64 | 1,482
interstitial cystitis 63 | 2,299
pituitary cancer 63 | 1,972
juvenile dermatomyositis 60 | 1,189
posterior fossa group A ependymoma 60 | 1,511
astrocytoma 59 | 1,493
acute quadriplegic myopathy 58 | 1,157
Waldenstrons macroglobulinemia 55 | 765
dermatomyositis 55 | 933
primary pancreatic ductal adenocarcinoma 54 | 1,271
medulloblastoma 51 | 1,524
atypical teratoid/rhabdoid tumor 46 | 1,095
tuberculosis 45 | 1,557
nasopharyngeal carcinoma 44 | 1,056
Atopic dermatitis 42 | 944
posterior fossa group B ependymoma 41 | 1,530
Intellectual disability 39 | 573
non primary Sjogren syndrome sicca 39 | 840
Duchenne muscular dystrophy 37 | 602
cutaneous lupus erythematosus 36 | 1,056
spina bifida 36 | 1,064
esophageal adenocarcinoma 35 | 737
Rheumatoid Arthritis 34 | 1,160
acute myeloid leukemia 34 | 780
Down syndrome 33 | 548
tuberculosis and treatment for 6 months 33 | 686
Prostatic Neoplasms 32 | 471
gastric carcinoma 32 | 832
Alzheimer's disease 31 | 644
active Crohn's disease 31 | 918
aldosterone-producing adenoma 30 | 664
Endometriosis 29 | 535
fibroadenoma 29 | 557
Obesity 27 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 499
IGA Glomerulonephritis 25 | 454
primary Sjogren syndrome 25 | 789
progressive supranuclear palsy 25 | 674
Amyotrophic Lateral Sclerosis 24 | 431
Polycystic Ovary Syndrome 24 | 332
Mammary Neoplasms 22 | 410
Stomach Neoplasms 22 | 282
pancreatic carcinoma 22 | 567
Myopathy 21 | 128
hepatocellular carcinoma 20 | 532
Liver carcinoma 19 | 217
hereditary spastic paraplegia 19 | 313
gastric cancer 18 | 430
inflammatory breast cancer 18 | 404
non-small cell lung carcinoma 17 | 413
Neurodegenerative disease 16 | 383
Neuropathy 16 | 210
Parkinson's disease 16 | 364
Vascular disease 16 | 281
Melanoma 15 | 261
tuberculosis and treatment for 3 months 15 | 327
Becker muscular dystrophy 14 | 187
Crohn's disease 14 | 304
Kidney disease 14 | 396
Schizophrenia 14 | 501
Myocardial Ischemia 13 | 169

Tissue

Female tissues 714 | 18,647
Nervous System 714 | 18,561
Cardiovascular System 713 | 17,958
Digestive Tract 713 | 18,473
Male tissues 712 | 17,969
Urinary Tract 712 | 18,444
Blood and immune system 711 | 17,995
Endocrine System 710 | 18,512
Liver and Pancreas 710 | 18,136
Skin and soft tissues 706 | 18,115
Respiratory system 704 | 17,484

Target Family

Non-IDG 419 | 11,971
Enzyme 179 | 4,146
Transcription Factor 58 | 1,400
Kinase 37 | 634
Transporter 12 | 473
Epigenetic 7 | 242
Ion Channel 6 | 341
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Muscle 721 | 721
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 62 TMEM62 Tdark Non-IDG 0.30 0.75 11
Replication protein A 32 kDa subunit RPA2 Tbio Non-IDG -1.76828 59.7 468
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Protein SMG5 SMG5 Tbio Non-IDG -0.98094 8.29 78
Replication factor C subunit 5 RFC5 Tbio Non-IDG -1.02728 11.1 64
Putative GTP-binding protein 6 GTPBP6 Tdark Non-IDG -1.08636 13.1 0
Acylphosphatase-2 ACYP2 Tbio Enzyme -1.25910 20.1 46
Ubiquitin carboxyl-terminal hydrolase 11 USP11 Tbio Enzyme -1.06624 14.9 210
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -1.95188 93.8 215
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.21530 0.00000 460