Development Level

Tbio 51 | 11,651
Tchem 15 | 1,388
Tclin 6 | 612
Tdark 6 | 6,593

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal vibrissa morphology 2 | 25
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
small superior vagus ganglion 2 | 74
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal sleep behavior 1 | 70
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 46 | 11,493
psoriasis 42 | 6,694
lung cancer 41 | 4,740
osteosarcoma 41 | 7,950
ovarian cancer 39 | 8,520
lung carcinoma 37 | 2,843
glioblastoma 35 | 5,792
interstitial cystitis 32 | 2,312
non-small cell lung cancer 32 | 2,890
tuberculosis 31 | 2,010
ulcerative colitis 30 | 1,819
Cancer 28 | 2,499
malignant mesothelioma 28 | 3,232
lung adenocarcinoma 26 | 2,716
cutaneous lupus erythematosus 25 | 1,057
medulloblastoma, large-cell 24 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
invasive ductal carcinoma 22 | 2,951
pancreatic cancer 22 | 2,398
Astrocytoma, Pilocytic 21 | 3,081
adult high grade glioma 20 | 3,801
cystic fibrosis 20 | 1,696
Multiple Sclerosis 18 | 540
atypical teratoid / rhabdoid tumor 18 | 5,112
subependymal giant cell astrocytoma 18 | 2,287
Rheumatoid arthritis 16 | 1,191
ependymoma 16 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
juvenile dermatomyositis 14 | 1,187
Asthma 13 | 385
Breast cancer 13 | 3,578
active Crohn's disease 13 | 922
colon cancer 13 | 1,478
Arthritis 12 | 290
Atopic dermatitis 12 | 952
Liver Cirrhosis, Experimental 12 | 769
Influenza 11 | 142
adrenocortical carcinoma 11 | 1,428
esophageal adenocarcinoma 11 | 737
group 3 medulloblastoma 11 | 4,104
primary Sjogren syndrome 11 | 735
Pneumonia 10 | 174
Systemic lupus erythematosus 10 | 194
gastric carcinoma 10 | 807
primary pancreatic ductal adenocarcinoma 10 | 1,109
primitive neuroectodermal tumor 10 | 3,035
Autosomal recessive predisposition 9 | 1,442
Schizophrenia 9 | 1,160
breast carcinoma 9 | 1,638
head and neck cancer and chronic obstructive pulmonary disease 9 | 239
inflammatory breast cancer 9 | 286
mucosa-associated lymphoid tissue lymphoma 9 | 484
periodontitis 9 | 293
Hypersensitivity 8 | 63
Lung disease 8 | 142
Pick disease 8 | 1,894
acute quadriplegic myopathy 8 | 1,158
astrocytoma 8 | 1,146
Allergic hypersensitivity disease 7 | 126
Breast Neoplasms 7 | 445
Dermatitis 7 | 157
Fever 7 | 138
Inflammatory bowel disease 7 | 151
Mammary Neoplasms 7 | 425
Multiple myeloma 7 | 1,332
Waldenstrons macroglobulinemia 7 | 765
diabetes mellitus 7 | 1,728
gastric cancer 7 | 459
sarcoidosis 7 | 370
Bipolar Disorder 6 | 666
Common cold 6 | 69
Hypereosinophilic syndrome 6 | 71
Hypersensitivity reaction type II disease 6 | 253
Vasculitis 6 | 80
group 4 medulloblastoma 6 | 1,855
hepatocellular carcinoma 6 | 547
oligodendroglioma 6 | 2,850
pancreatic carcinoma 6 | 562
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 468
spina bifida 6 | 1,074
Allergic rhinitis 5 | 95
Arthritis, Rheumatoid 5 | 174
Atherosclerosis 5 | 291
COPD 5 | 118
Contact Dermatitis 5 | 81
Human immunodeficiency virus infectious disease 5 | 138
Influenza, Human 5 | 51
Kidney disease 5 | 430
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
nasopharyngeal carcinoma 5 | 1,058
nephrosclerosis 5 | 333
non primary Sjogren syndrome sicca 5 | 891
pediatric high grade glioma 5 | 1,064
Kidney cancer 4 | 2,613
acute myeloid leukemia 4 | 783

Tissue

Blood and immune system 76 | 16,909
Urinary Tract 76 | 16,678
Digestive Tract 75 | 17,369
Respiratory system 75 | 16,393
Skin and soft tissues 75 | 17,230
Endocrine System 74 | 18,159
Liver and Pancreas 74 | 16,750
Female tissues 73 | 17,400
Male tissues 73 | 17,142
Nervous System 73 | 16,725
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 12 | 4,145
GPCR 8 | 408
Transcription Factor 6 | 1,400
Kinase 3 | 634
Transporter 1 | 473

Jensen-KB Tissue

Monocyte 78 | 78
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase ARIH1 ARIH1 Tbio Enzyme -2.26078 179.2 81
CMRF35-like molecule 2 CD300E Tbio Non-IDG -0.94922 8.61 140
C-X-C motif chemokine 5 CXCL5 Tbio Non-IDG -2.44551 266.4 370
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.03585 113.9 202
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.31972 17.9 168
MAP/microtubule affinity-regulating kinase 3 MARK3 Tchem Kinase -2.48165 289.6 314
C-X-C chemokine receptor type 4 CXCR4 Tclin GPCR -3.41606 2525.3 1240
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Roquin-2 RC3H2 Tdark Non-IDG -0.78651 4.13 33
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718