Development Level

Tbio 259 | 11,178
Tdark 56 | 6,569
Tchem 43 | 1,885
Tclin 6 | 612

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 32 | 979
embryonic lethality prior to o... 15 | 239
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to t... 11 | 278
increased total body fat amoun... 7 | 134
abnormal behavior 6 | 298
abnormal embryo size 6 | 220
abnormal retina morphology 5 | 71
decreased fasted circulating g... 5 | 65
enlarged heart 5 | 210
male infertility 5 | 123
abnormal coat-hair pigmentatio... 4 | 64
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
decreased bone mineral content 4 | 151
decreased lean body mass 4 | 135
decreased mean corpuscular hem... 4 | 50
decreased mean corpuscular vol... 4 | 79
decreased vertical activity 4 | 208
increased lean body mass 4 | 172
increased startle reflex 4 | 112
abnormal skin morphology 3 | 50
abnormal sleep behavior 3 | 70
abnormal testis morphology 3 | 43
decreased circulating triglyce... 3 | 79
decreased heart weight 3 | 27
decreased total body fat amoun... 3 | 207
enlarged spleen 3 | 41
hypoactivity 3 | 132
increased body length 3 | 32
increased circulating alkaline... 3 | 122
increased circulating sodium l... 3 | 71
increased grip strength 3 | 41
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal heart left ventricle ... 2 | 16
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal skin coloration 2 | 25
abnormal spleen morphology 2 | 55
cardiovascular system phenotyp... 2 | 36
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased heart rate variabili... 2 | 13
decreased prepulse inhibition 2 | 82
edema 2 | 59
enlarged epididymis 2 | 31
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased cardiac muscle contr... 2 | 8
increased circulating HDL chol... 2 | 80
increased circulating serum al... 2 | 22
increased circulating thyroxin... 2 | 7
increased fasted circulating g... 2 | 76
increased heart rate 2 | 23
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
small adrenal glands 2 | 16
small superior vagus ganglion 2 | 74
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
long tibia 1 | 25
prenatal lethality 1 | 28
small thymus 1 | 16
tremors 1 | 39
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 245 | 11,192
ovarian cancer 212 | 8,297
osteosarcoma 181 | 7,766
glioblastoma 139 | 5,635
psoriasis 130 | 6,514
medulloblastoma, large-cell 125 | 6,086
atypical teratoid / rhabdoid tumor 114 | 4,971
ependymoma 112 | 4,559
lung cancer 93 | 4,607
intraductal papillary-mucinous neoplasm (IPMN) 88 | 3,204
group 3 medulloblastoma 86 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 81 | 2,902
adult high grade glioma 78 | 3,701
Breast cancer 77 | 3,469
Cancer 76 | 2,388
invasive ductal carcinoma 74 | 2,867
Astrocytoma, Pilocytic 70 | 3,006
intraductal papillary-mucinous adenoma (IPMA) 70 | 2,872
subependymal giant cell astrocytoma 69 | 2,230
oligodendroglioma 68 | 2,768
malignant mesothelioma 67 | 3,135
primitive neuroectodermal tumor 66 | 2,957
pancreatic cancer 65 | 2,322
lung adenocarcinoma 62 | 2,627
non-small cell lung cancer 61 | 2,799
pancreatic ductal adenocarcinoma liver metastasis 57 | 1,911
acute quadriplegic myopathy 56 | 1,133
astrocytic glioma 56 | 2,530
Kidney cancer 51 | 2,548
lung carcinoma 50 | 2,755
diabetes mellitus 45 | 1,683
juvenile dermatomyositis 45 | 1,147
Pick disease 44 | 1,856
tuberculosis 44 | 1,963
ulcerative colitis 44 | 1,765
group 4 medulloblastoma 43 | 1,806
ductal carcinoma in situ 42 | 1,686
primary pancreatic ductal adenocarcinoma 41 | 1,071
breast carcinoma 40 | 1,589
Multiple myeloma 39 | 1,296
cystic fibrosis 38 | 1,629
adrenocortical carcinoma 34 | 1,385
interstitial cystitis 34 | 2,237
active Crohn's disease 33 | 882
pediatric high grade glioma 33 | 1,035
pituitary cancer 33 | 1,915
astrocytoma 32 | 1,113
Rheumatoid arthritis 30 | 1,156
Autosomal recessive predisposition 28 | 1,407
colon cancer 28 | 1,428
dermatomyositis 26 | 941
non primary Sjogren syndrome sicca 26 | 861
gastric carcinoma 25 | 781
Duchenne muscular dystrophy 24 | 587
autosomal dominant Emery-Dreifuss muscular dystrophy 23 | 492
Waldenstrons macroglobulinemia 22 | 742
Neurodegenerative disease 21 | 402
Schizophrenia 21 | 1,136
cutaneous lupus erythematosus 21 | 1,016
Liver Cirrhosis, Experimental 20 | 733
Intellectual disability 19 | 998
nasopharyngeal carcinoma 19 | 1,024
Atopic dermatitis 18 | 915
Melanoma 18 | 689
Vascular disease 18 | 294
progressive supranuclear palsy 18 | 656
Amyotrophic lateral sclerosis 17 | 437
acute myeloid leukemia 17 | 760
aldosterone-producing adenoma 17 | 646
Down syndrome 16 | 480
Liver cancer 16 | 589
Pre-Eclampsia 16 | 64
pancreatic carcinoma 16 | 555
Alzheimer's disease 15 | 640
Ankylosing spondylitis 15 | 134
Cognitive delay 15 | 596
Global developmental delay 15 | 596
Mental and motor retardation 15 | 596
Prostatic Neoplasms 15 | 472
posterior fossa group A ependymoma 15 | 456
Behcet's disease 14 | 87
Human immunodeficiency virus infectious disease 14 | 136
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Muscle hypotonia 14 | 562
Parkinson's disease 14 | 378
Psoriasis susceptibility 1 14 | 14
Psoriatic arthritis 14 | 84
Stevens-Johnson syndrome 14 | 92
medulloblastoma 14 | 702
spina bifida 14 | 1,053
Multiple Sclerosis 13 | 527
esophageal adenocarcinoma 13 | 696
fibroadenoma 13 | 538
primary Sjogren syndrome 13 | 710
Dull intelligence 12 | 634
Low intelligence 12 | 634
Mental Retardation 12 | 634
Mental deficiency 12 | 634
Poor school performance 12 | 634
active ulcerative colitis 12 | 736

Tissue

Endocrine System 346 | 18,159
Female tissues 341 | 17,400
Male tissues 341 | 17,142
Skin and soft tissues 341 | 17,230
Liver and Pancreas 340 | 16,750
Blood and immune system 339 | 16,909
Urinary Tract 339 | 16,678
Digestive Tract 338 | 17,369
Respiratory system 338 | 16,393
Nervous System 336 | 16,725
Cardiovascular System 335 | 15,192

Target Family

Non-IDG 213 | 12,091
Enzyme 108 | 4,145
Transporter 13 | 473
Transcription Factor 12 | 1,400
Epigenetic 6 | 242
Kinase 5 | 634
GPCR 3 | 408
Ion Channel 2 | 344
TF/Epigenetic 1 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Melanoma cell line 364 | 364
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65
Zinc finger protein 526 ZNF526 Tdark Transcription Factor 0.70 0.20 51
Protein RCC2 RCC2 Tbio Non-IDG -1.49831 31.4 148
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Basic leucine zipper transcriptional factor ATF-like BATF Tbio Transcription Factor -1.88914 81.4 286
Forkhead box protein J2 FOXJ2 Tbio Transcription Factor -1.74969 54.7 138
Vacuolar protein sorting-associated protein 18 homolog VPS18 Tbio Non-IDG -1.92505 80.9 117
Nodal modulator 1 NOMO1 Tbio Non-IDG -1.36102 22.5 260
KAT8 regulatory NSL complex subunit 2 KANSL2 Tbio Non-IDG -0.72700 5.47 32
HLA class I histocompatibility antigen, Cw-16 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0