Development Level

Tbio 246 | 10,625
Tdark 68 | 7,003
Tchem 43 | 1,890
Tclin 6 | 602

Collection

Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 24 | 633
embryonic lethality prior to o... 13 | 148
embryonic lethality prior to t... 10 | 187
abnormal retina morphology 7 | 100
preweaning lethality, incomple... 6 | 260
increased or absent threshold ... 5 | 128
abnormal behavior 4 | 226
abnormal embryo size 4 | 112
decreased fasted circulating g... 4 | 49
increased circulating HDL chol... 4 | 63
increased circulating sodium l... 4 | 71
increased grip strength 4 | 83
increased total body fat amoun... 4 | 57
abnormal coat/hair pigmentatio... 3 | 54
abnormal sleep behavior 3 | 63
abnormal testis morphology 3 | 30
cardiovascular system phenotyp... 3 | 35
decreased bone mineral content 3 | 157
decreased mean corpuscular hem... 3 | 34
decreased mean corpuscular vol... 3 | 50
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased circulating alkaline... 3 | 119
increased circulating choleste... 3 | 53
increased mean corpuscular hem... 3 | 93
prenatal lethality prior to he... 3 | 64
small testis 3 | 37
abnormal bone structure 2 | 131
abnormal gait 2 | 51
decreased body weight 2 | 174
decreased circulating alanine ... 2 | 53
decreased circulating insulin ... 2 | 75
decreased circulating phosphat... 2 | 15
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased heart rate variabili... 2 | 11
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
increased circulating phosphat... 2 | 24
increased circulating serum al... 2 | 25
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased hematocrit 2 | 36
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
increased mature B cell number 2 | 12
increased mean corpuscular hem... 2 | 25
increased mean corpuscular vol... 2 | 91
increased startle reflex 2 | 38
straub tail 2 | 26
abnormal behavioral response t... 1 | 52
abnormal embryo turning 1 | 15
abnormal eye size 1 | 11
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal optic disc morphology 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased total retina thickne... 1 | 20
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased body length 1 | 20
increased bone mineral density 1 | 52
increased cardiac muscle contr... 1 | 5
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
long tibia 1 | 13
premature death 1 | 5
short tibia 1 | 82
thrombocytopenia 1 | 46
vertebral fusion 1 | 23

Disease

ovarian cancer 218 | 8,484
osteosarcoma 186 | 7,933
glioblastoma 136 | 5,572
psoriasis 136 | 6,685
medulloblastoma, large-cell 129 | 6,234
atypical teratoid / rhabdoid tumor 96 | 4,369
lung cancer 94 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 90 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 81 | 2,988
Cancer 79 | 2,346
invasive ductal carcinoma 77 | 2,950
Breast cancer 73 | 3,094
ependymoma 73 | 2,514
pilocytic astrocytoma 73 | 3,086
subependymal giant cell astrocytoma 72 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 71 | 2,956
oligodendroglioma 71 | 2,849
malignant mesothelioma 68 | 3,162
pediatric high grade glioma 68 | 2,712
primitive neuroectodermal tumor 68 | 3,031
pancreatic cancer 67 | 2,300
lung adenocarcinoma 64 | 2,713
non-small cell lung cancer 64 | 2,798
acute quadriplegic myopathy 57 | 1,157
pancreatic ductal adenocarcinoma liver metastasis 55 | 1,795
lung carcinoma 53 | 2,844
ulcerative colitis 51 | 2,087
group 3 medulloblastoma 50 | 2,254
astrocytic glioma 49 | 2,241
adult high grade glioma 48 | 2,148
group 4 medulloblastoma 48 | 1,875
primary pancreatic ductal adenocarcinoma 47 | 1,271
diabetes mellitus 46 | 1,663
Pick disease 45 | 1,893
juvenile dermatomyositis 45 | 1,189
ductal carcinoma in situ 44 | 1,745
astrocytoma 43 | 1,493
Carcinoma 40 | 2,147
Multiple myeloma 40 | 1,327
breast carcinoma 40 | 1,614
cystic fibrosis 39 | 1,665
adrenocortical carcinoma 37 | 1,427
posterior fossa group A ependymoma 37 | 1,511
sonic hedgehog group medulloblastoma 35 | 1,482
active Crohn's disease 34 | 918
interstitial cystitis 34 | 2,299
pituitary cancer 33 | 1,972
Rheumatoid Arthritis 32 | 1,160
tuberculosis 31 | 1,557
atypical teratoid/rhabdoid tumor 30 | 1,095
colon cancer 30 | 1,475
dermatomyositis 27 | 933
gastric carcinoma 27 | 832
Duchenne muscular dystrophy 26 | 602
medulloblastoma 25 | 1,524
Waldenstrons macroglobulinemia 24 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 499
non primary Sjogren syndrome sicca 24 | 840
posterior fossa group B ependymoma 24 | 1,530
Neurodegenerative disease 23 | 383
cutaneous lupus erythematosus 22 | 1,056
nasopharyngeal carcinoma 21 | 1,056
IGA Glomerulonephritis 20 | 454
Atopic dermatitis 19 | 944
acute myeloid leukemia 19 | 780
progressive supranuclear palsy 19 | 674
tuberculosis and treatment for 6 months 18 | 686
Down syndrome 17 | 548
Vascular disease 17 | 281
aldosterone-producing adenoma 17 | 664
Alzheimer's disease 16 | 644
Amyotrophic Lateral Sclerosis 16 | 431
Melanoma 16 | 261
pancreatic carcinoma 16 | 567
pre-eclampsia 16 | 67
Ankylosing spondylitis 15 | 138
Human immunodeficiency virus infectious disease 15 | 92
Multiple Sclerosis 15 | 498
Parkinson's disease 15 | 364
Prostatic Neoplasms 15 | 471
primary Sjogren syndrome 15 | 789
spina bifida 15 | 1,064
Psoriatic arthritis 14 | 83
esophageal adenocarcinoma 14 | 737
fibroadenoma 14 | 557
Obesity 13 | 616
Endometriosis 12 | 535
Intellectual disability 12 | 573
glioblastoma multiforme 12 | 347
Liver carcinoma 11 | 217
Mammary Neoplasms 11 | 410
hepatocellular carcinoma 11 | 532
interstitial lung disease 11 | 291
Oculocutaneous albinism 10 | 27
Polycystic Ovary Syndrome 10 | 332
hereditary spastic paraplegia 10 | 313
Neoplasm Invasiveness 9 | 127
Neuropathy 9 | 210
gastric cancer 8 | 430
mucosa-associated lymphoid tissue lymphoma 8 | 480

Tissue

Female tissues 346 | 18,647
Nervous System 346 | 18,561
Cardiovascular System 345 | 17,958
Endocrine System 345 | 18,512
Skin and soft tissues 344 | 18,115
Urinary Tract 344 | 18,444
Blood and immune system 343 | 17,995
Digestive Tract 343 | 18,473
Male tissues 343 | 17,969
Liver and Pancreas 340 | 18,136
Respiratory system 336 | 17,484

Target Family

Non-IDG 213 | 11,971
Enzyme 107 | 4,146
Transporter 13 | 473
Transcription Factor 12 | 1,400
Epigenetic 6 | 242
Kinase 5 | 634
GPCR 3 | 406
Ion Channel 2 | 341
TF/Epigenetic 1 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Melanoma cell line 363 | 363
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoplasmin HSP90B1 Tchem Non-IDG -2.72785 604.5 748
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Dymeclin DYM Tbio Non-IDG -1.45800 31.6 59
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Ankyrin repeat domain-containing protein 26 ANKRD26 Tbio Non-IDG -1.28843 22.9 87
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Fatty acid synthase FASN Tchem Enzyme -2.49948 348.5 388
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B MGAT4B Tdark Enzyme -0.75856 4.88 37
Calumenin CALU Tbio Non-IDG -1.76431 61.4 157