Development Level

Tbio 262 | 11,445
Tdark 57 | 6,588
Tchem 39 | 1,598
Tclin 6 | 613

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 32 | 979
embryonic lethality prior to o... 15 | 239
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to t... 11 | 278
increased total body fat amoun... 7 | 134
abnormal behavior 6 | 298
abnormal embryo size 6 | 220
abnormal retina morphology 5 | 71
decreased fasted circulating g... 5 | 65
enlarged heart 5 | 210
male infertility 5 | 123
abnormal coat-hair pigmentatio... 4 | 64
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
decreased bone mineral content 4 | 151
decreased lean body mass 4 | 135
decreased mean corpuscular hem... 4 | 50
decreased mean corpuscular vol... 4 | 79
decreased vertical activity 4 | 208
increased lean body mass 4 | 172
increased startle reflex 4 | 112
abnormal skin morphology 3 | 50
abnormal sleep behavior 3 | 70
abnormal testis morphology 3 | 43
decreased circulating triglyce... 3 | 79
decreased heart weight 3 | 27
decreased total body fat amoun... 3 | 207
enlarged spleen 3 | 41
hypoactivity 3 | 132
increased body length 3 | 32
increased circulating alkaline... 3 | 122
increased circulating sodium l... 3 | 71
increased grip strength 3 | 41
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal heart left ventricle ... 2 | 16
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal skin coloration 2 | 25
abnormal spleen morphology 2 | 55
cardiovascular system phenotyp... 2 | 36
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased heart rate variabili... 2 | 13
decreased prepulse inhibition 2 | 82
edema 2 | 59
enlarged epididymis 2 | 31
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased cardiac muscle contr... 2 | 8
increased circulating HDL chol... 2 | 80
increased circulating serum al... 2 | 22
increased circulating thyroxin... 2 | 7
increased fasted circulating g... 2 | 76
increased heart rate 2 | 23
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
small adrenal glands 2 | 16
small superior vagus ganglion 2 | 74
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
convulsive seizures 1 | 13
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
long tibia 1 | 25
prenatal lethality 1 | 28
small thymus 1 | 16
tremors 1 | 39
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 254 | 11,493
ovarian cancer 218 | 8,520
osteosarcoma 187 | 7,950
glioblastoma 144 | 5,792
psoriasis 136 | 6,694
medulloblastoma, large-cell 130 | 6,241
atypical teratoid / rhabdoid tumor 121 | 5,112
ependymoma 115 | 4,679
lung cancer 96 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 90 | 3,291
group 3 medulloblastoma 88 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 82 | 2,989
adult high grade glioma 81 | 3,801
Cancer 79 | 2,499
Breast cancer 78 | 3,578
invasive ductal carcinoma 76 | 2,951
Astrocytoma, Pilocytic 74 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 72 | 2,955
subependymal giant cell astrocytoma 72 | 2,287
oligodendroglioma 71 | 2,850
malignant mesothelioma 70 | 3,232
primitive neuroectodermal tumor 69 | 3,035
pancreatic cancer 68 | 2,398
lung adenocarcinoma 64 | 2,716
non-small cell lung cancer 64 | 2,890
astrocytic glioma 59 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 59 | 1,962
acute quadriplegic myopathy 57 | 1,158
Kidney cancer 54 | 2,613
lung carcinoma 53 | 2,843
diabetes mellitus 46 | 1,728
ulcerative colitis 46 | 1,819
Pick disease 45 | 1,894
group 4 medulloblastoma 45 | 1,855
juvenile dermatomyositis 45 | 1,187
tuberculosis 44 | 2,010
ductal carcinoma in situ 43 | 1,745
primary pancreatic ductal adenocarcinoma 43 | 1,109
Multiple myeloma 41 | 1,332
breast carcinoma 40 | 1,638
cystic fibrosis 40 | 1,696
adrenocortical carcinoma 37 | 1,428
pediatric high grade glioma 35 | 1,064
interstitial cystitis 34 | 2,312
active Crohn's disease 33 | 922
astrocytoma 33 | 1,146
pituitary cancer 33 | 1,972
Rheumatoid arthritis 32 | 1,191
colon cancer 30 | 1,478
Autosomal recessive predisposition 29 | 1,442
dermatomyositis 27 | 966
gastric carcinoma 27 | 807
Duchenne muscular dystrophy 26 | 601
non primary Sjogren syndrome sicca 26 | 891
Waldenstrons macroglobulinemia 24 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 510
Neurodegenerative disease 22 | 414
cutaneous lupus erythematosus 22 | 1,057
Liver Cirrhosis, Experimental 21 | 769
Schizophrenia 21 | 1,160
Vascular disease 21 | 319
nasopharyngeal carcinoma 21 | 1,058
Atopic dermatitis 19 | 952
Intellectual disability 19 | 1,016
acute myeloid leukemia 19 | 783
progressive supranuclear palsy 19 | 676
Melanoma 18 | 711
Amyotrophic lateral sclerosis 17 | 451
aldosterone-producing adenoma 17 | 665
Alzheimer's disease 16 | 658
Down syndrome 16 | 499
Liver cancer 16 | 604
Pre-Eclampsia 16 | 68
pancreatic carcinoma 16 | 562
Ankylosing spondylitis 15 | 140
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Human immunodeficiency virus infectious disease 15 | 138
Mental and motor retardation 15 | 608
Multiple Sclerosis 15 | 540
Prostatic Neoplasms 15 | 495
medulloblastoma 15 | 720
posterior fossa group A ependymoma 15 | 468
spina bifida 15 | 1,074
Behcet's disease 14 | 89
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Muscle hypotonia 14 | 571
Parkinson's disease 14 | 392
Psoriasis susceptibility 1 14 | 14
Psoriatic arthritis 14 | 86
Stevens-Johnson syndrome 14 | 92
esophageal adenocarcinoma 14 | 737
fibroadenoma 14 | 559
primary Sjogren syndrome 13 | 735
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Obesity 12 | 678
Poor school performance 12 | 645

Tissue

Endocrine System 346 | 18,159
Female tissues 341 | 17,400
Male tissues 341 | 17,142
Skin and soft tissues 341 | 17,230
Liver and Pancreas 340 | 16,750
Blood and immune system 339 | 16,909
Urinary Tract 339 | 16,678
Digestive Tract 338 | 17,369
Respiratory system 338 | 16,393
Nervous System 336 | 16,725
Cardiovascular System 335 | 15,192

Target Family

Non-IDG 213 | 12,091
Enzyme 108 | 4,145
Transporter 13 | 473
Transcription Factor 12 | 1,400
Epigenetic 6 | 242
Kinase 5 | 634
GPCR 3 | 408
Ion Channel 2 | 344
TF/Epigenetic 1 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Melanoma cell line 364 | 364
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Transmembrane protein 64 TMEM64 Tdark Non-IDG -0.22185 1.46 9
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
RNMT-activating mini protein FAM103A1 Tbio Non-IDG -0.24304 0.91 14
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 UAP1L1 Tdark Enzyme 0.90 0.11 70
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
SAFB-like transcription modulator SLTM Tdark Non-IDG -0.51977 2.83 111