Development Level

Tbio 284 | 11,651
Tdark 73 | 6,593
Tchem 45 | 1,388
Tclin 13 | 612

Collection

Kinase: IDG Consortium (Target... 5 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 34 | 979
preweaning lethality, incomple... 16 | 499
abnormal embryo size 12 | 220
embryonic lethality prior to o... 9 | 239
embryonic lethality prior to t... 9 | 278
enlarged heart 9 | 210
abnormal behavior 8 | 298
abnormal heart morphology 8 | 162
abnormal seminal vesicle morph... 7 | 114
decreased bone mineral content 7 | 151
small superior vagus ganglion 6 | 74
decreased body weight 5 | 161
decreased fasted circulating g... 5 | 65
decreased vertical activity 5 | 208
edema 5 | 59
embryonic growth retardation 5 | 106
improved glucose tolerance 5 | 79
increased circulating alkaline... 5 | 122
increased erythrocyte cell num... 5 | 39
increased lean body mass 5 | 172
increased total body fat amoun... 5 | 134
abnormal bone structure 4 | 187
abnormal craniofacial morpholo... 4 | 33
abnormal lens morphology 4 | 81
anophthalmia 4 | 33
cataract 4 | 92
decreased circulating LDL chol... 4 | 38
decreased lean body mass 4 | 135
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
decreased total body fat amoun... 4 | 207
hydrometra 4 | 53
increased hematocrit 4 | 46
increased hemoglobin content 4 | 45
increased monocyte cell number 4 | 63
prenatal lethality prior to he... 4 | 87
tremors 4 | 39
abnormal bone mineralization 3 | 38
abnormal coat-hair pigmentatio... 3 | 64
abnormal eye morphology 3 | 68
abnormal limb morphology 3 | 13
abnormal spleen morphology 3 | 55
decreased bone mineral density 3 | 126
decreased circulating alkaline... 3 | 46
decreased circulating insulin ... 3 | 76
decreased circulating phosphat... 3 | 27
decreased circulating total pr... 3 | 49
decreased prepulse inhibition 3 | 82
enlarged seminal vesicle 3 | 10
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased mean corpuscular hem... 3 | 96
increased or absent threshold ... 3 | 101
male infertility 3 | 123
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal body wall morphology 2 | 9
abnormal epididymis morphology 2 | 42
abnormal facial morphology 2 | 17
abnormal head size 2 | 6
abnormal kidney morphology 2 | 65
abnormal limb bud morphology 2 | 17
abnormal retina morphology 2 | 71
abnormal skin coloration 2 | 25
abnormal snout morphology 2 | 23
cleft palate 2 | 8
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased heart left ventricle... 2 | 28
decreased mean corpuscular hem... 2 | 50
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
enlarged epididymis 2 | 31
facial cleft 2 | 3
female infertility 2 | 60
impaired righting response 2 | 26
increased body length 2 | 32
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
microphthalmia 2 | 26
persistence of hyaloid vascula... 2 | 33

Disease

Carcinoma 261 | 11,493
ovarian cancer 224 | 8,520
osteosarcoma 191 | 7,950
psoriasis 167 | 6,694
lung cancer 136 | 4,740
medulloblastoma, large-cell 133 | 6,241
glioblastoma 127 | 5,792
atypical teratoid / rhabdoid tumor 121 | 5,112
Breast cancer 111 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 96 | 3,291
invasive ductal carcinoma 93 | 2,951
Cancer 90 | 2,499
ependymoma 90 | 4,679
malignant mesothelioma 90 | 3,232
group 3 medulloblastoma 88 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 82 | 2,955
adult high grade glioma 79 | 3,801
non-small cell lung cancer 74 | 2,890
interstitial cystitis 72 | 2,312
lung adenocarcinoma 70 | 2,716
pancreatic cancer 70 | 2,398
primitive neuroectodermal tumor 67 | 3,035
ductal carcinoma in situ 62 | 1,745
Astrocytoma, Pilocytic 61 | 3,081
breast carcinoma 58 | 1,638
lung carcinoma 57 | 2,843
astrocytic glioma 56 | 2,597
tuberculosis 56 | 2,010
oligodendroglioma 52 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 51 | 1,962
pituitary cancer 51 | 1,972
ulcerative colitis 51 | 1,819
Kidney cancer 49 | 2,613
subependymal giant cell astrocytoma 49 | 2,287
colon cancer 45 | 1,478
Pick disease 43 | 1,894
diabetes mellitus 42 | 1,728
cystic fibrosis 39 | 1,696
Multiple myeloma 36 | 1,332
non primary Sjogren syndrome sicca 34 | 891
group 4 medulloblastoma 33 | 1,855
astrocytoma 32 | 1,146
cutaneous lupus erythematosus 32 | 1,057
primary pancreatic ductal adenocarcinoma 32 | 1,109
spina bifida 32 | 1,074
Schizophrenia 31 | 1,160
juvenile dermatomyositis 31 | 1,187
Autosomal recessive predisposition 29 | 1,442
adrenocortical carcinoma 29 | 1,428
pediatric high grade glioma 29 | 1,064
Rheumatoid arthritis 28 | 1,191
acute quadriplegic myopathy 28 | 1,158
nasopharyngeal carcinoma 28 | 1,058
esophageal adenocarcinoma 27 | 737
Atopic dermatitis 24 | 952
Breast Neoplasms 24 | 445
Mammary Neoplasms 24 | 425
Waldenstrons macroglobulinemia 24 | 765
Prostatic Neoplasms 23 | 495
dermatomyositis 23 | 966
Obesity 21 | 678
gastric carcinoma 21 | 807
medulloblastoma 20 | 720
Endometriosis 19 | 540
Intellectual disability 19 | 1,016
fibroadenoma 19 | 559
active ulcerative colitis 18 | 764
pancreatic carcinoma 18 | 562
Polycystic ovary syndrome 17 | 360
Bipolar Disorder 16 | 666
Liver Cirrhosis, Experimental 16 | 769
active Crohn's disease 16 | 922
gastric cancer 16 | 459
posterior fossa group A ependymoma 16 | 468
Alzheimer's disease 15 | 658
Down syndrome 15 | 499
hepatocellular carcinoma 15 | 547
Epilepsy 14 | 792
primary Sjogren syndrome 14 | 735
Liver cancer 13 | 604
acute myeloid leukemia 13 | 783
mucosa-associated lymphoid tissue lymphoma 13 | 484
progressive supranuclear palsy 13 | 676
Depressive disorder 12 | 409
Duchenne muscular dystrophy 12 | 601
Mental Depression 12 | 333
Stomach Neoplasms 12 | 300
aldosterone-producing adenoma 12 | 665
chronic rhinosinusitis 12 | 512
sonic hedgehog group medulloblastoma 12 | 467
Amyotrophic lateral sclerosis 11 | 451
Atherosclerosis 11 | 291
Cognitive delay 11 | 608
Colorectal Neoplasms 11 | 243
Global developmental delay 11 | 608
Mammary Neoplasms, Experimental 11 | 154
Mental and motor retardation 11 | 608
Neurodegenerative disease 11 | 414
urothelial carcinoma 11 | 318

Tissue

Female tissues 407 | 17,400
Digestive Tract 404 | 17,369
Endocrine System 404 | 18,159
Male tissues 404 | 17,142
Skin and soft tissues 404 | 17,230
Liver and Pancreas 403 | 16,750
Urinary Tract 403 | 16,678
Blood and immune system 397 | 16,909
Nervous System 391 | 16,725
Respiratory system 391 | 16,393
Cardiovascular System 374 | 15,192

Target Family

Non-IDG 238 | 12,091
Enzyme 99 | 4,145
Transcription Factor 26 | 1,400
Kinase 22 | 634
Transporter 13 | 473
Ion Channel 6 | 344
GPCR 4 | 408
Nuclear Receptor 4 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Mammary gland 415 | 415
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -2.09381 115.1 104
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
Sphingomyelin phosphodiesterase 4 SMPD4 Tbio Enzyme -0.89678 7.05 66
Solute carrier family 52, riboflavin transporter, member 3 SLC52A3 Tbio Transporter -1.82473 71.3 31
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
CCR4-NOT transcription complex subunit 11 CNOT11 Tbio Non-IDG -1.18963 14.4 52
Alpha-(1,3)-fucosyltransferase 7 FUT7 Tchem Enzyme -1.85814 81.0 121
Nuclear-interacting partner of ALK ZC3HC1 Tbio Non-IDG -2.13812 136.0 171
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172