Development Level

Tbio 256 | 10,625
Tdark 92 | 7,003
Tchem 54 | 1,890
Tclin 13 | 602

Collection

Eligible Kinase Proteins 5 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 21 | 633
preweaning lethality, incomple... 10 | 260
decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
increased mean corpuscular hem... 5 | 93
abnormal behavior 4 | 226
abnormal embryo size 4 | 112
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
decreased fasted circulating g... 4 | 49
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
increased or absent threshold ... 4 | 128
tremors 4 | 34
abnormal bone mineralization 3 | 55
abnormal coat/hair pigmentatio... 3 | 54
abnormal lens morphology 3 | 73
abnormal limb morphology 3 | 7
anophthalmia 3 | 20
cataract 3 | 26
decreased caudal vertebrae num... 3 | 49
decreased circulating LDL chol... 3 | 37
decreased circulating glucose ... 3 | 121
decreased circulating serum al... 3 | 79
edema 3 | 11
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
increased mean corpuscular vol... 3 | 91
prenatal lethality prior to he... 3 | 64
abnormal body wall morphology 2 | 7
abnormal craniofacial morpholo... 2 | 12
abnormal epididymis morphology 2 | 31
abnormal eye morphology 2 | 38
abnormal facial morphology 2 | 9
abnormal iris morphology 2 | 12
abnormal limb bud morphology 2 | 15
abnormal retinal pigmentation 2 | 61
abnormal snout morphology 2 | 18
cleft palate 2 | 6
decreased KLRG1-positive NK ce... 2 | 9
decreased body length 2 | 108
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating total pr... 2 | 41
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
facial cleft 2 | 3
hyperactivity 2 | 108
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased circulating phosphat... 2 | 24
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
persistence of hyaloid vascula... 2 | 22
polydactyly 2 | 22
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
decreased NK cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased effector memory CD8-... 1 | 24
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased thoracic vertebrae n... 1 | 7
embryonic growth retardation 1 | 28
female infertility 1 | 34
impaired righting response 1 | 19
increased NK cell number 1 | 19
increased body length 1 | 20
increased circulating aspartat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased sacral vertebrae num... 1 | 62
prenatal lethality 1 | 16

Disease

ovarian cancer 223 | 8,484
osteosarcoma 191 | 7,933
psoriasis 169 | 6,685
medulloblastoma, large-cell 133 | 6,234
lung cancer 131 | 4,466
glioblastoma 122 | 5,572
atypical teratoid / rhabdoid tumor 109 | 4,369
Breast cancer 99 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 96 | 3,289
invasive ductal carcinoma 93 | 2,950
malignant mesothelioma 90 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,988
Cancer 85 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 82 | 2,956
interstitial cystitis 72 | 2,299
non-small cell lung cancer 71 | 2,798
lung adenocarcinoma 70 | 2,713
pancreatic cancer 69 | 2,300
primitive neuroectodermal tumor 67 | 3,031
ductal carcinoma in situ 62 | 1,745
pilocytic astrocytoma 61 | 3,086
pediatric high grade glioma 59 | 2,712
lung carcinoma 57 | 2,844
breast carcinoma 55 | 1,614
ulcerative colitis 55 | 2,087
ependymoma 53 | 2,514
oligodendroglioma 52 | 2,849
group 3 medulloblastoma 51 | 2,254
pituitary cancer 51 | 1,972
astrocytic glioma 50 | 2,241
adult high grade glioma 49 | 2,148
subependymal giant cell astrocytoma 49 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,795
tuberculosis 48 | 1,557
colon cancer 45 | 1,475
Pick disease 43 | 1,893
Carcinoma 41 | 2,147
diabetes mellitus 41 | 1,663
medulloblastoma 39 | 1,524
astrocytoma 38 | 1,493
posterior fossa group A ependymoma 38 | 1,511
cystic fibrosis 37 | 1,665
Multiple myeloma 36 | 1,327
primary pancreatic ductal adenocarcinoma 35 | 1,271
group 4 medulloblastoma 34 | 1,875
non primary Sjogren syndrome sicca 34 | 840
cutaneous lupus erythematosus 32 | 1,056
spina bifida 32 | 1,064
juvenile dermatomyositis 31 | 1,189
adrenocortical carcinoma 29 | 1,427
sonic hedgehog group medulloblastoma 29 | 1,482
acute quadriplegic myopathy 28 | 1,157
nasopharyngeal carcinoma 28 | 1,056
Rheumatoid Arthritis 27 | 1,160
esophageal adenocarcinoma 27 | 737
posterior fossa group B ependymoma 25 | 1,530
Atopic dermatitis 24 | 944
Mammary Neoplasms 24 | 410
Waldenstrons macroglobulinemia 24 | 765
Prostatic Neoplasms 23 | 471
dermatomyositis 23 | 933
gastric carcinoma 22 | 832
Endometriosis 19 | 535
atypical teratoid/rhabdoid tumor 19 | 1,095
fibroadenoma 19 | 557
pancreatic carcinoma 18 | 567
Alzheimer's disease 17 | 644
Polycystic Ovary Syndrome 17 | 332
active Crohn's disease 16 | 918
Obesity 15 | 616
gastric cancer 15 | 430
Down syndrome 14 | 548
hepatocellular carcinoma 14 | 532
primary Sjogren syndrome 14 | 789
tuberculosis and treatment for 6 months 14 | 686
active ulcerative colitis 13 | 477
acute myeloid leukemia 13 | 780
mucosa-associated lymphoid tissue lymphoma 13 | 480
progressive supranuclear palsy 13 | 674
Duchenne muscular dystrophy 12 | 602
aldosterone-producing adenoma 12 | 664
chronic rhinosinusitis 12 | 512
inflammatory breast cancer 12 | 404
Amyotrophic Lateral Sclerosis 11 | 431
Intellectual disability 11 | 573
Mammary Neoplasms, Experimental 11 | 150
Stomach Neoplasms 11 | 282
urothelial carcinoma 11 | 318
Animal Mammary Neoplasms 10 | 136
Atherosclerosis 10 | 275
IGA Glomerulonephritis 10 | 454
Osteoporosis 10 | 257
Schizophrenia 10 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
non-small cell lung carcinoma 10 | 413
Coronary artery disease 9 | 240
Crohn's disease 9 | 304
Kidney disease 9 | 396
Liver carcinoma 9 | 217
glioblastoma multiforme 9 | 347

Tissue

Female tissues 410 | 18,647
Endocrine System 409 | 18,512
Cardiovascular System 408 | 17,958
Digestive Tract 408 | 18,473
Liver and Pancreas 408 | 18,136
Nervous System 408 | 18,561
Blood and immune system 407 | 17,995
Urinary Tract 406 | 18,444
Male tissues 405 | 17,969
Respiratory system 404 | 17,484
Skin and soft tissues 403 | 18,115

Target Family

Non-IDG 238 | 11,971
Enzyme 99 | 4,146
Transcription Factor 26 | 1,400
Kinase 22 | 634
Transporter 13 | 473
Ion Channel 6 | 341
GPCR 4 | 406
Nuclear Receptor 4 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Mammary gland 415 | 415
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 485 ZNF485 Tdark Transcription Factor 0.00000 48
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Sialidase-3 NEU3 Tbio Enzyme -1.97558 109.4 23
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
Filensin BFSP1 Tbio Non-IDG -2.08549 124.5 154
Host cell factor 1 HCFC1 Tbio Non-IDG -2.50024 341.6 160
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.72231 55.8 158
Tigger transposable element-derived protein 5 TIGD5 Tdark Non-IDG 1.20 0.02 19
H(+)/Cl(-) exchange transporter 7 CLCN7 Tbio Ion Channel -1.91579 94.4 137