Development Level

Tbio 56 | 10,625
Tdark 8 | 7,003
Tchem 7 | 1,890
Tclin 3 | 602

IMPC Phenotype

preweaning lethality, complete... 5 | 633
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
embryonic lethality prior to t... 2 | 187
abnormal bone mineralization 1 | 55
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal head morphology 1 | 10
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal vitreous body morphol... 1 | 7
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased red blood cell distr... 1 | 11
embryonic growth retardation 1 | 28
immune system phenotype 1 | 17
increased IgG1 level 1 | 1
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating glycerol... 1 | 11
increased circulating thyroxin... 1 | 7
increased erythrocyte cell num... 1 | 26
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15

Disease

ovarian cancer 53 | 8,491
osteosarcoma 46 | 7,933
psoriasis 27 | 6,685
glioblastoma 26 | 5,572
lung cancer 25 | 4,473
medulloblastoma, large-cell 22 | 6,234
atypical teratoid / rhabdoid tumor 20 | 4,369
malignant mesothelioma 20 | 3,163
Carcinoma 19 | 2,147
group 3 medulloblastoma 17 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
subependymal giant cell astrocytoma 17 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
oligodendroglioma 15 | 2,849
primitive neuroectodermal tumor 15 | 3,031
Breast cancer 14 | 3,098
astrocytic glioma 14 | 2,241
invasive ductal carcinoma 14 | 2,950
Cancer 13 | 2,346
ependymoma 13 | 2,514
Pick disease 12 | 1,893
Rheumatoid Arthritis 12 | 1,170
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
ulcerative colitis 12 | 2,087
non-small cell lung cancer 11 | 2,798
adult high grade glioma 10 | 2,148
lung carcinoma 10 | 2,844
pediatric high grade glioma 10 | 2,712
pilocytic astrocytoma 10 | 3,086
posterior fossa group B ependymoma 10 | 1,530
tuberculosis 10 | 1,563
Intellectual disability 9 | 573
colon cancer 9 | 1,475
dermatomyositis 9 | 966
diabetes mellitus 9 | 1,663
lung adenocarcinoma 9 | 2,714
ductal carcinoma in situ 8 | 1,745
Obesity 7 | 616
breast carcinoma 7 | 1,614
pituitary cancer 7 | 1,972
spina bifida 7 | 1,064
Bardet-Biedl Syndrome 6 | 40
Joubert syndrome 6 | 62
Microcephaly 6 | 149
Neurodegenerative disease 6 | 383
adrenocortical carcinoma 6 | 1,427
astrocytoma 6 | 1,493
interstitial cystitis 6 | 2,299
primary Sjogren syndrome 6 | 788
Autistic Disorder 5 | 320
Multiple Sclerosis 5 | 498
Multiple myeloma 5 | 1,327
Nephronophthisis 5 | 74
Schizophrenia 5 | 503
cutaneous lupus erythematosus 5 | 1,056
juvenile dermatomyositis 5 | 1,189
posterior fossa group A ependymoma 5 | 1,511
tuberculosis and treatment for 6 months 5 | 686
Amyotrophic Lateral Sclerosis 4 | 432
Atopic dermatitis 4 | 944
Down syndrome 4 | 548
Epilepsy 4 | 346
Hypersensitivity reaction type II disease 4 | 235
Narcolepsy 4 | 69
Polydactyly 4 | 93
Senior-Loken syndrome 4 | 22
Severe Combined Immunodeficiency 4 | 46
Type 1 diabetes mellitus 4 | 104
acute quadriplegic myopathy 4 | 1,157
atypical teratoid/rhabdoid tumor 4 | 1,095
cystic fibrosis 4 | 1,670
group 4 medulloblastoma 4 | 1,875
medulloblastoma 4 | 1,524
non primary Sjogren syndrome sicca 4 | 840
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
systemic lupus erythematosus 4 | 172
Alzheimer's disease 3 | 644
Blindness 3 | 84
Cardiomyopathy 3 | 110
Ciliopathy 3 | 57
Endometriosis 3 | 535
IGA Glomerulonephritis 3 | 454
Kidney disease 3 | 397
Liver disease 3 | 219
Neoplastic Syndromes, Hereditary 3 | 48
Neutropenia 3 | 78
Peripheral Neuropathy 3 | 303
Sensorineural hearing loss 3 | 107
Vasculitis 3 | 64
acute myeloid leukemia 3 | 785
aldosterone-producing adenoma 3 | 664
chronic rhinosinusitis 3 | 512
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
hepatocellular carcinoma 3 | 550
inflammatory breast cancer 3 | 404
nasopharyngeal carcinoma 3 | 1,056
pancreatic cancer 3 | 2,300
sarcoidosis 3 | 368

Tissue

Blood and immune system 72 | 17,994
Cardiovascular System 72 | 17,957
Digestive Tract 72 | 18,472
Endocrine System 72 | 18,511
Female tissues 72 | 18,646
Liver and Pancreas 72 | 18,135
Nervous System 72 | 18,560
Respiratory system 72 | 17,483
Urinary Tract 72 | 18,443
Male tissues 71 | 17,968
Skin and soft tissues 71 | 18,114

Target Family

Non-IDG 57 | 11,969
Enzyme 7 | 4,146
Transporter 3 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 341
Kinase 1 | 634

Jensen-KB Tissue

Lymphoblast 74 | 74
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HAUS augmin-like complex subunit 2 HAUS2 Tdark Non-IDG 1.15 0.07 35
Centrosomal protein of 41 kDa CEP41 Tdark Non-IDG -0.38839 3.35 44
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.39396 233.2 634
Protein ELYS AHCTF1 Tbio Non-IDG -1.33445 22.8 57
Erythroid differentiation-related factor 1 EDRF1 Tdark Non-IDG -0.49402 4.21 41
Centriolar coiled-coil protein of 110 kDa CCP110 Tbio Non-IDG -1.43015 25.5 104
Protein TALPID3 KIAA0586 Tbio Non-IDG -1.36553 24.5 5
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.64918 48.2 71
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.55826 362.4 351