Development Level

Tbio 62 | 11,651
Tdark 5 | 6,593
Tchem 4 | 1,388
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
increased erythrocyte cell num... 2 | 39
increased total body fat amoun... 2 | 134
microphthalmia 2 | 26
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123
polydactyly 1 | 7
preweaning lethality, incomple... 1 | 499
protruding tongue 1 | 3
short tibia 1 | 97
small adrenal glands 1 | 16

Disease

Carcinoma 59 | 11,493
ovarian cancer 53 | 8,520
osteosarcoma 46 | 7,950
psoriasis 28 | 6,694
glioblastoma 26 | 5,792
group 3 medulloblastoma 25 | 4,104
lung cancer 25 | 4,740
Kidney cancer 23 | 2,613
atypical teratoid / rhabdoid tumor 23 | 5,112
medulloblastoma, large-cell 22 | 6,241
ependymoma 20 | 4,679
malignant mesothelioma 20 | 3,232
Breast cancer 17 | 3,578
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
subependymal giant cell astrocytoma 17 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Autosomal recessive predisposition 15 | 1,442
astrocytic glioma 15 | 2,597
oligodendroglioma 15 | 2,850
primitive neuroectodermal tumor 15 | 3,035
Intellectual disability 14 | 1,016
invasive ductal carcinoma 14 | 2,951
Cancer 13 | 2,499
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Pick disease 12 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Rheumatoid arthritis 11 | 1,191
diabetes mellitus 11 | 1,728
non-small cell lung cancer 11 | 2,890
tuberculosis 11 | 2,010
Astrocytoma, Pilocytic 10 | 3,081
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Short stature 9 | 531
colon cancer 9 | 1,478
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
ulcerative colitis 9 | 1,819
Seizures 8 | 596
ductal carcinoma in situ 8 | 1,745
Cerebellar Ataxia 7 | 304
Epilepsy 7 | 792
Joubert syndrome 7 | 66
Neurodegenerative disease 7 | 414
Obesity 7 | 678
Small head 7 | 374
breast carcinoma 7 | 1,638
pituitary cancer 7 | 1,972
posterior fossa group B ependymoma 7 | 416
spina bifida 7 | 1,074
Hypertensive disease 6 | 292
Increase in blood pressure 6 | 119
Microcephaly 6 | 166
Nystagmus 6 | 317
Optic Atrophy 6 | 242
Schizophrenia 6 | 1,160
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
interstitial cystitis 6 | 2,312
primary Sjogren syndrome 6 | 735
Bardet-Biedl syndrome 5 | 51
Cataract 5 | 297
Crohn's disease 5 | 321
Decreased visual acuity, progressive 5 | 36
Gait abnormality 5 | 135
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Muscle hypotonia 5 | 571
Nephronophthisis 5 | 80
Neutrophil count decreased 5 | 47
Progressive visual loss 5 | 36
Recurrent upper respiratory tract infection 5 | 21
Retinal Degeneration 5 | 106
Retinitis Pigmentosa 5 | 226
cutaneous lupus erythematosus 5 | 1,057
juvenile dermatomyositis 5 | 1,187
Acquired scoliosis 4 | 281
Amyotrophic lateral sclerosis 4 | 451
Atopic dermatitis 4 | 952
Attention deficit hyperactivity disorder 4 | 278
Curvature of spine 4 | 282
Down syndrome 4 | 499
Hypersensitivity reaction type II disease 4 | 253
Kidney Failure 4 | 111
Liver cancer 4 | 604
Melanoma 4 | 711
Neuropathy 4 | 261
Renal Insufficiency 4 | 90
Renal failure in adulthood 4 | 76
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
progressive supranuclear palsy 4 | 676

Tissue

Blood and immune system 70 | 16,909
Digestive Tract 70 | 17,369
Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750
Male tissues 70 | 17,142
Nervous System 70 | 16,725
Respiratory system 70 | 16,393
Skin and soft tissues 70 | 17,230
Urinary Tract 70 | 16,678
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 7 | 4,145
Transporter 3 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

Jensen-KB Tissue

Lymphoblast 74 | 74
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromatin assembly factor 1 subunit B CHAF1B Tbio Non-IDG -1.02167 9.99 181
Centriolar coiled-coil protein of 110 kDa CCP110 Tbio Non-IDG -1.45267 26.4 109
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Serum paraoxonase/arylesterase 1 PON1 Tbio Enzyme -3.39345 2648.8 361
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tbio Ion Channel -2.28525 197.9 203
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.15430 1384.8 332
Interferon alpha-21 IFNA21 Tbio Non-IDG -0.88029 5.87 91
HLA class II histocompatibility antigen, DRB1-15 beta chain HLA-DRB1 Tbio Non-IDG -2.84258 1665.5 489
DNA-binding protein RFXANK RFXANK Tbio Non-IDG -2.85535 702.6 190
Hamartin TSC1 Tbio Non-IDG -2.25451 173.9 1622