Development Level

Tbio 90 | 10,625
Tdark 41 | 7,003
Tchem 14 | 1,890
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
abnormal behavior 4 | 226
abnormal bone structure 3 | 131
decreased circulating serum al... 3 | 79
decreased total body fat amoun... 3 | 186
increased lean body mass 3 | 107
abnormal hair growth 2 | 8
abnormal joint morphology 2 | 14
abnormal lens morphology 2 | 73
abnormal tail morphology 2 | 17
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating serum al... 2 | 25
increased mean platelet volume 2 | 19
increased sacral vertebrae num... 2 | 62
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal facial morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
aorta dilation 1 | 3
cleft palate 1 | 6
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased effector memory CD8-... 1 | 24
decreased heart left ventricle... 1 | 2
decreased heart rate 1 | 10
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased neutrophil cell numb... 1 | 37
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
hemorrhage 1 | 12
increased NK T cell number 1 | 11
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating calcium ... 1 | 32
increased circulating fructosa... 1 | 11
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased heart weight 1 | 37
increased marginal zone B cell... 1 | 3
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
increased thoracic vertebrae n... 1 | 8
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
prolonged PQ interval 1 | 3
prolonged RR interval 1 | 2
prolonged ST segment 1 | 4
small seminal vesicle 1 | 6
small testis 1 | 37
vertebral fusion 1 | 23

Disease

osteosarcoma 96 | 7,933
ovarian cancer 83 | 8,484
psoriasis 56 | 6,685
medulloblastoma, large-cell 50 | 6,234
glioblastoma 46 | 5,572
invasive ductal carcinoma 41 | 2,950
lung cancer 39 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
atypical teratoid / rhabdoid tumor 35 | 4,369
interstitial cystitis 34 | 2,299
lung adenocarcinoma 31 | 2,713
ulcerative colitis 31 | 2,087
primitive neuroectodermal tumor 30 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,956
group 3 medulloblastoma 27 | 2,254
pilocytic astrocytoma 27 | 3,086
primary Sjogren syndrome 26 | 789
Breast cancer 25 | 3,094
lung carcinoma 25 | 2,844
malignant mesothelioma 25 | 3,162
pancreatic cancer 25 | 2,300
oligodendroglioma 24 | 2,849
subependymal giant cell astrocytoma 24 | 2,287
Carcinoma 23 | 2,147
Pick disease 22 | 1,893
ependymoma 22 | 2,514
non-small cell lung cancer 22 | 2,798
ductal carcinoma in situ 21 | 1,745
pituitary cancer 21 | 1,972
colon cancer 20 | 1,475
adult high grade glioma 19 | 2,148
breast carcinoma 18 | 1,614
group 4 medulloblastoma 18 | 1,875
pediatric high grade glioma 18 | 2,712
adrenocortical carcinoma 16 | 1,427
astrocytoma 16 | 1,493
Cancer 15 | 2,346
cutaneous lupus erythematosus 15 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
tuberculosis 15 | 1,557
acute quadriplegic myopathy 14 | 1,157
juvenile dermatomyositis 14 | 1,189
active Crohn's disease 13 | 918
astrocytic glioma 13 | 2,241
cystic fibrosis 13 | 1,665
Atopic dermatitis 12 | 944
Rheumatoid Arthritis 12 | 1,160
medulloblastoma 12 | 1,524
nasopharyngeal carcinoma 12 | 1,056
posterior fossa group A ependymoma 12 | 1,511
posterior fossa group B ependymoma 12 | 1,530
primary pancreatic ductal adenocarcinoma 12 | 1,271
gastric carcinoma 11 | 832
spina bifida 11 | 1,064
tuberculosis and treatment for 6 months 11 | 686
atypical teratoid/rhabdoid tumor 10 | 1,095
diabetes mellitus 10 | 1,663
hepatocellular carcinoma 10 | 532
mucosa-associated lymphoid tissue lymphoma 10 | 480
acute myeloid leukemia 9 | 780
Multiple myeloma 8 | 1,327
dermatomyositis 8 | 933
pancreatic carcinoma 8 | 567
progressive supranuclear palsy 8 | 674
sonic hedgehog group medulloblastoma 8 | 1,482
Intellectual disability 7 | 573
aldosterone-producing adenoma 7 | 664
fibroadenoma 7 | 557
gastric cancer 7 | 430
non-small cell lung carcinoma 7 | 413
periodontitis 7 | 269
urothelial carcinoma 7 | 318
Chronic Lymphocytic Leukemia 6 | 242
Duchenne muscular dystrophy 6 | 602
Peripheral Neuropathy 6 | 303
Waldenstrons macroglobulinemia 6 | 765
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
tuberculosis and treatment for 3 months 6 | 327
cystic fibrosis and chronic rhinosinusitis 5 | 213
glioblastoma multiforme 5 | 347
head and neck cancer 5 | 270
inflammatory breast cancer 5 | 404
interstitial lung disease 5 | 291
Asthma 4 | 349
IGA Glomerulonephritis 4 | 454
Influenza 4 | 142
Melanoma 4 | 261
Multiple Sclerosis 4 | 498
non diabetic and post-ischemic heart failure 4 | 200
systemic lupus erythematosus 4 | 156
Alzheimer's disease 3 | 644
Autistic Disorder 3 | 320
Chronic obstructive pulmonary disease 3 | 146
Crohn's disease 3 | 304
Inflammatory bowel disease 3 | 142
Prostatic Neoplasms 3 | 471
adrenocortical adenoma 3 | 134
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499

Tissue

Blood and immune system 148 | 17,995
Digestive Tract 148 | 18,473
Endocrine System 148 | 18,512
Female tissues 148 | 18,647
Liver and Pancreas 148 | 18,136
Nervous System 148 | 18,561
Urinary Tract 148 | 18,444
Male tissues 147 | 17,969
Skin and soft tissues 147 | 18,115
Respiratory system 146 | 17,484
Cardiovascular System 145 | 17,958

Target Family

Non-IDG 86 | 11,971
Enzyme 37 | 4,146
Transcription Factor 10 | 1,400
Epigenetic 4 | 242
Kinase 4 | 634
Transporter 3 | 473
Ion Channel 2 | 341
GPCR 1 | 406
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Lymph node 148 | 148
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
STE20-related kinase adapter protein alpha STRADA Tbio Kinase -1.42357 23.3 215
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
Disintegrin and metalloproteinase domain-containing protein 19 ADAM19 Tbio Enzyme -1.55795 41.8 160
Protein transport protein Sec61 subunit alpha isoform 1 SEC61A1 Tbio Non-IDG -2.43916 280.2 94
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.38460 284.0 184
Transcription termination factor 2, mitochondrial MTERF2 Tbio Non-IDG -0.72291 5.58 35
Zinc finger protein 831 ZNF831 Tdark Transcription Factor 0.00000 5
FXYD domain-containing ion transport regulator 6 FXYD6 Tbio Ion Channel -1.08048 14.6 65
Myb/SANT-like DNA-binding domain-containing protein 4 MSANTD4 Tdark Non-IDG 0.00000 11
GTPase IMAP family member 8 GIMAP8 Tbio Enzyme -0.97962 10.3 103