Development Level

Tbio 97 | 11,651
Tdark 39 | 6,593
Tchem 12 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 5 | 298
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased bone mineral content 3 | 151
decreased circulating choleste... 3 | 93
embryonic lethality prior to o... 3 | 239
increased lean body mass 3 | 172
abnormal facial morphology 2 | 17
abnormal hair growth 2 | 10
abnormal neural tube closure 2 | 46
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
increased mean platelet volume 2 | 45
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal external female genit... 1 | 1
abnormal external male genital... 1 | 1
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal humerus morphology 1 | 11
abnormal ileum morphology 1 | 2
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged epididymis 1 | 31
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral density 1 | 72
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Carcinoma 103 | 11,493
osteosarcoma 97 | 7,950
ovarian cancer 85 | 8,520
psoriasis 55 | 6,694
glioblastoma 51 | 5,792
medulloblastoma, large-cell 51 | 6,241
group 3 medulloblastoma 44 | 4,104
lung cancer 43 | 4,740
atypical teratoid / rhabdoid tumor 42 | 5,112
invasive ductal carcinoma 42 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
ependymoma 37 | 4,679
interstitial cystitis 35 | 2,312
Breast cancer 32 | 3,578
lung adenocarcinoma 32 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 30 | 2,989
primitive neuroectodermal tumor 30 | 3,035
adult high grade glioma 29 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
pancreatic cancer 29 | 2,398
Astrocytoma, Pilocytic 27 | 3,081
Kidney cancer 27 | 2,613
ulcerative colitis 27 | 1,819
lung carcinoma 26 | 2,843
malignant mesothelioma 26 | 3,232
non-small cell lung cancer 25 | 2,890
oligodendroglioma 24 | 2,850
primary Sjogren syndrome 24 | 735
subependymal giant cell astrocytoma 24 | 2,287
Pick disease 23 | 1,894
pituitary cancer 22 | 1,972
tuberculosis 22 | 2,010
ductal carcinoma in situ 21 | 1,745
colon cancer 20 | 1,478
breast carcinoma 18 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Cancer 17 | 2,499
astrocytic glioma 17 | 2,597
adrenocortical carcinoma 16 | 1,428
cutaneous lupus erythematosus 16 | 1,057
acute quadriplegic myopathy 15 | 1,158
juvenile dermatomyositis 15 | 1,187
cystic fibrosis 14 | 1,696
group 4 medulloblastoma 14 | 1,855
active Crohn's disease 13 | 922
Atopic dermatitis 12 | 952
Rheumatoid arthritis 12 | 1,191
astrocytoma 12 | 1,146
diabetes mellitus 12 | 1,728
nasopharyngeal carcinoma 12 | 1,058
gastric carcinoma 11 | 807
mucosa-associated lymphoid tissue lymphoma 11 | 484
spina bifida 11 | 1,074
Liver cancer 10 | 604
hepatocellular carcinoma 10 | 547
primary pancreatic ductal adenocarcinoma 10 | 1,109
Liver Cirrhosis, Experimental 9 | 769
Melanoma 9 | 711
Multiple myeloma 9 | 1,332
acute myeloid leukemia 9 | 783
Intellectual disability 8 | 1,016
dermatomyositis 8 | 966
pancreatic carcinoma 8 | 562
pediatric high grade glioma 8 | 1,064
progressive supranuclear palsy 8 | 676
Schizophrenia 7 | 1,160
aldosterone-producing adenoma 7 | 665
chronic rhinosinusitis 7 | 512
fibroadenoma 7 | 559
gastric cancer 7 | 459
periodontitis 7 | 293
posterior fossa group A ependymoma 7 | 468
urothelial carcinoma 7 | 318
Autosomal recessive predisposition 6 | 1,442
Chronic Lymphocytic Leukemia 6 | 262
Multiple Sclerosis 6 | 540
Waldenstrons macroglobulinemia 6 | 765
active ulcerative colitis 6 | 764
esophageal adenocarcinoma 6 | 737
tuberculosis and treatment for 6 months 6 | 409
Duchenne muscular dystrophy 5 | 601
Hepatomegaly 5 | 285
Skin cancer 5 | 469
cystic fibrosis and chronic rhinosinusitis 5 | 214
head and neck cancer 5 | 271
interstitial lung disease 5 | 298
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung carcinoma 5 | 317
Asthma 4 | 385
Cholestasis 4 | 155
Endometrial cancer 4 | 311
Influenza 4 | 142
Large intestine cancer 4 | 126
Lymphoid leukemia 4 | 160
atypical teratoid/rhabdoid tumor 4 | 357
medulloblastoma 4 | 720
non diabetic and post-ischemic heart failure 4 | 200
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis and treatment for 3 months 4 | 179
Prostatic Neoplasms 3 | 495

Tissue

Blood and immune system 151 | 16,909
Digestive Tract 151 | 17,369
Skin and soft tissues 151 | 17,230
Endocrine System 150 | 18,159
Female tissues 150 | 17,400
Liver and Pancreas 150 | 16,750
Male tissues 149 | 17,142
Respiratory system 149 | 16,393
Urinary Tract 149 | 16,678
Cardiovascular System 145 | 15,192
Nervous System 142 | 16,725

Target Family

Non-IDG 88 | 12,091
Enzyme 38 | 4,145
Transcription Factor 10 | 1,400
Epigenetic 4 | 242
Kinase 4 | 634
Transporter 3 | 473
Ion Channel 2 | 344
GPCR 1 | 408
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Lymph node 151 | 151
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oxidation resistance protein 1 OXR1 Tbio Non-IDG -1.67505 49.4 144
Inactive serine protease PAMR1 PAMR1 Tdark Enzyme -0.86262 5.98 22
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Fc receptor-like protein 5 FCRL5 Tbio Non-IDG -1.23637 21.0 145
T-cell surface protein tactile CD96 Tbio Non-IDG -2.05505 111.7 205
T-cell immunoreceptor with Ig and ITIM domains TIGIT Tbio Non-IDG -1.72549 54.9 142
Armadillo repeat-containing protein 1 ARMC1 Tbio Non-IDG -1.58920 38.0 157
E3 ubiquitin-protein ligase TRIM56 TRIM56 Tbio Enzyme -0.69719 6.78 109
E3 ubiquitin-protein ligase MSL2 MSL2 Tbio Enzyme -1.78868 59.2 117
Calpain-2 catalytic subunit CAPN2 Tchem Non-IDG -1.69585 48.5 220