Development Level

Tbio 366 | 10,625
Tdark 106 | 7,003
Tchem 74 | 1,890
Tclin 16 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 32 | 633
decreased lean body mass 10 | 195
increased circulating alkaline... 10 | 119
embryonic lethality prior to o... 8 | 148
embryonic lethality prior to t... 8 | 187
increased or absent threshold ... 8 | 128
abnormal behavior 7 | 226
abnormal retina morphology 7 | 100
decreased body length 7 | 108
decreased body weight 7 | 174
decreased bone mineral density 7 | 126
decreased circulating choleste... 7 | 85
abnormal embryo size 6 | 112
decreased circulating glucose ... 6 | 121
decreased circulating triglyce... 6 | 83
decreased grip strength 6 | 123
abnormal bone mineralization 5 | 55
decreased bone mineral content 5 | 157
increased grip strength 5 | 83
preweaning lethality, incomple... 5 | 260
short tibia 5 | 82
abnormal bone structure 4 | 131
abnormal coat/hair pigmentatio... 4 | 54
decreased CD8-positive, alpha-... 4 | 26
decreased circulating HDL chol... 4 | 77
decreased circulating LDL chol... 4 | 37
decreased total body fat amoun... 4 | 186
hyperactivity 4 | 108
increased fasted circulating g... 4 | 68
increased sacral vertebrae num... 4 | 62
abnormal lens morphology 3 | 73
cardiovascular system phenotyp... 3 | 35
decreased CD4-positive, alpha ... 3 | 19
decreased T cell number 3 | 31
decreased caudal vertebrae num... 3 | 49
decreased circulating alanine ... 3 | 53
decreased circulating alkaline... 3 | 41
decreased circulating fructosa... 3 | 31
decreased circulating serum al... 3 | 79
decreased circulating sodium l... 3 | 18
decreased lumbar vertebrae num... 3 | 62
decreased prepulse inhibition 3 | 52
enlarged heart 3 | 111
female infertility 3 | 34
hypoactivity 3 | 89
immune system phenotype 3 | 17
improved glucose tolerance 3 | 56
increased T cell number 3 | 15
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
increased circulating sodium l... 3 | 71
male infertility 3 | 62
abnormal blood vessel morpholo... 2 | 2
abnormal eye morphology 2 | 38
abnormal neural tube closure 2 | 37
abnormal retinal pigmentation 2 | 61
abnormal sacral vertebrae morp... 2 | 5
abnormal sleep behavior 2 | 63
decreased B cell number 2 | 30
decreased Ly6C-positive mature... 2 | 4
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased circulating amylase ... 2 | 24
decreased circulating chloride... 2 | 32
decreased circulating free fat... 2 | 39
decreased circulating total pr... 2 | 41
decreased effector memory CD8-... 2 | 24
decreased heart weight 2 | 44
decreased leukocyte cell numbe... 2 | 54
decreased mature B cell number 2 | 25
decreased mean corpuscular vol... 2 | 50
decreased monocyte cell number 2 | 28
decreased startle reflex 2 | 48
decreased total retina thickne... 2 | 20
embryonic growth retardation 2 | 28
impaired glucose tolerance 2 | 52
increased B cell number 2 | 23
increased CD11b-high dendritic... 2 | 5
increased NK cell number 2 | 19
increased circulating LDL chol... 2 | 15
increased circulating calcium ... 2 | 32
increased circulating creatini... 2 | 29
increased circulating glucose ... 2 | 16
increased circulating iron lev... 2 | 25
increased eosinophil cell numb... 2 | 9
increased exploration in new e... 2 | 56
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
increased monocyte cell number 2 | 27
increased neutrophil cell numb... 2 | 15
increased prepulse inhibition 2 | 21
increased rib number 2 | 41
thrombocytopenia 2 | 46
thrombocytosis 2 | 23
trunk curl 2 | 15
decreased circulating bilirubi... 1 | 14
decreased red blood cell distr... 1 | 11
decreased vertical activity 1 | 22

Disease

ovarian cancer 325 | 8,484
osteosarcoma 307 | 7,933
psoriasis 213 | 6,685
glioblastoma 194 | 5,572
medulloblastoma, large-cell 191 | 6,234
lung cancer 179 | 4,466
atypical teratoid / rhabdoid tumor 133 | 4,369
malignant mesothelioma 115 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 111 | 3,289
non-small cell lung cancer 106 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 105 | 2,988
invasive ductal carcinoma 105 | 2,950
Breast cancer 96 | 3,094
pediatric high grade glioma 94 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 93 | 2,956
Cancer 92 | 2,346
subependymal giant cell astrocytoma 92 | 2,287
interstitial cystitis 90 | 2,299
oligodendroglioma 90 | 2,849
ulcerative colitis 90 | 2,087
pilocytic astrocytoma 89 | 3,086
Multiple myeloma 85 | 1,327
primitive neuroectodermal tumor 85 | 3,031
lung adenocarcinoma 84 | 2,713
group 3 medulloblastoma 79 | 2,254
lung carcinoma 75 | 2,844
astrocytoma 73 | 1,493
primary Sjogren syndrome 72 | 789
adult high grade glioma 69 | 2,148
pancreatic cancer 68 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 63 | 1,795
Pick disease 60 | 1,893
diabetes mellitus 60 | 1,663
astrocytic glioma 59 | 2,241
ductal carcinoma in situ 58 | 1,745
adrenocortical carcinoma 57 | 1,427
ependymoma 57 | 2,514
Carcinoma 56 | 2,147
Waldenstrons macroglobulinemia 56 | 765
cutaneous lupus erythematosus 56 | 1,056
colon cancer 55 | 1,475
group 4 medulloblastoma 55 | 1,875
tuberculosis 53 | 1,557
juvenile dermatomyositis 52 | 1,189
posterior fossa group A ependymoma 48 | 1,511
sonic hedgehog group medulloblastoma 48 | 1,482
Rheumatoid Arthritis 47 | 1,160
acute quadriplegic myopathy 47 | 1,157
breast carcinoma 47 | 1,614
dermatomyositis 44 | 933
pituitary cancer 44 | 1,972
Atopic dermatitis 42 | 944
nasopharyngeal carcinoma 41 | 1,056
cystic fibrosis 36 | 1,665
medulloblastoma 35 | 1,524
atypical teratoid/rhabdoid tumor 34 | 1,095
primary pancreatic ductal adenocarcinoma 34 | 1,271
posterior fossa group B ependymoma 33 | 1,530
spina bifida 33 | 1,064
active Crohn's disease 32 | 918
tuberculosis and treatment for 6 months 32 | 686
IGA Glomerulonephritis 29 | 454
Intellectual disability 28 | 573
non primary Sjogren syndrome sicca 26 | 840
Alzheimer's disease 25 | 644
acute myeloid leukemia 25 | 780
pancreatic carcinoma 23 | 567
Multiple Sclerosis 22 | 498
aldosterone-producing adenoma 21 | 664
hepatocellular carcinoma 21 | 532
Endometriosis 20 | 535
esophageal adenocarcinoma 20 | 737
progressive supranuclear palsy 20 | 674
Amyotrophic Lateral Sclerosis 19 | 431
Neurodegenerative disease 19 | 383
gastric carcinoma 19 | 832
periodontitis 19 | 269
Chronic Lymphocytic Leukemia 18 | 242
Crohn's disease 16 | 304
Duchenne muscular dystrophy 16 | 602
Schizophrenia 16 | 501
sarcoidosis 16 | 358
Asthma 15 | 349
gastric cancer 15 | 430
Obesity 14 | 616
Prostatic Neoplasms 14 | 471
hereditary spastic paraplegia 14 | 313
non-small cell lung carcinoma 14 | 413
inflammatory breast cancer 13 | 404
systemic lupus erythematosus 13 | 156
Down syndrome 12 | 548
Kidney disease 12 | 396
Stomach Neoplasms 12 | 282
fibroadenoma 12 | 557
Cerebrovascular disease 11 | 231
Heart disease 11 | 279
Peripheral Neuropathy 11 | 303
Polycystic Ovary Syndrome 11 | 332
Vascular disease 11 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499

Tissue

Liver and Pancreas 551 | 18,136
Nervous System 551 | 18,561
Blood and immune system 550 | 17,995
Cardiovascular System 550 | 17,958
Digestive Tract 550 | 18,473
Female tissues 550 | 18,647
Endocrine System 549 | 18,512
Male tissues 549 | 17,969
Urinary Tract 547 | 18,444
Respiratory system 545 | 17,484
Skin and soft tissues 542 | 18,115

Target Family

Non-IDG 329 | 11,971
Enzyme 130 | 4,146
Transcription Factor 40 | 1,400
Kinase 27 | 634
Transporter 12 | 473
Epigenetic 11 | 242
Ion Channel 6 | 341
GPCR 4 | 406
TF/Epigenetic 3 | 38

Jensen-KB Tissue

Lymph 562 | 562
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coiled-coil domain-containing protein 15 CCDC15 Tdark Non-IDG 0.00000 53
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Ankyrin repeat domain-containing protein 26 ANKRD26 Tbio Non-IDG -1.28843 22.9 87
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Lymphotoxin-alpha LTA Tbio Non-IDG -2.84770 612.8 461
PHD finger-like domain-containing protein 5A PHF5A Tbio Epigenetic -1.94489 96.2 127
Apoptosis inhibitor 5 API5 Tbio Non-IDG -1.32754 23.5 171
Ribonuclease inhibitor RNH1 Tbio Enzyme -2.79304 640.5 234
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.75991 594.0 437
Transmembrane protein 267 TMEM267 Tdark Non-IDG 0.00000 4