Development Level

Tbio 69 | 10,625
Tchem 19 | 1,890
Tdark 12 | 7,003
Tclin 4 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal embryo size 2 | 112
decreased fasted circulating g... 2 | 49
abnormal eye morphology 1 | 38
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal spinal cord morpholog... 1 | 8
craniofacial phenotype 1 | 9
decreased body weight 1 | 174
decreased coping response 1 | 5
decreased startle reflex 1 | 48
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hemorrhage 1 | 12
herniated abdominal wall 1 | 4
hydrometra 1 | 13
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
limb grasping 1 | 35
pale yolk sac 1 | 12
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 65 | 8,484
osteosarcoma 49 | 7,933
lung cancer 45 | 4,466
psoriasis 45 | 6,685
glioblastoma 34 | 5,572
medulloblastoma, large-cell 34 | 6,234
atypical teratoid / rhabdoid tumor 33 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,289
Breast cancer 27 | 3,094
Cancer 26 | 2,346
malignant mesothelioma 26 | 3,162
non-small cell lung cancer 24 | 2,798
oligodendroglioma 24 | 2,849
ependymoma 21 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
invasive ductal carcinoma 20 | 2,950
pancreatic cancer 20 | 2,300
pilocytic astrocytoma 19 | 3,086
ductal carcinoma in situ 18 | 1,745
lung adenocarcinoma 17 | 2,713
primitive neuroectodermal tumor 17 | 3,031
ulcerative colitis 17 | 2,087
Multiple myeloma 16 | 1,327
astrocytic glioma 16 | 2,241
group 3 medulloblastoma 16 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
pediatric high grade glioma 16 | 2,712
Rheumatoid Arthritis 15 | 1,160
acute quadriplegic myopathy 15 | 1,157
astrocytoma 15 | 1,493
colon cancer 15 | 1,475
Carcinoma 14 | 2,147
adult high grade glioma 13 | 2,148
interstitial cystitis 13 | 2,299
lung carcinoma 13 | 2,844
subependymal giant cell astrocytoma 13 | 2,287
pituitary cancer 12 | 1,972
cystic fibrosis 11 | 1,665
diabetes mellitus 11 | 1,663
posterior fossa group A ependymoma 11 | 1,511
primary pancreatic ductal adenocarcinoma 11 | 1,271
tuberculosis 11 | 1,557
group 4 medulloblastoma 10 | 1,875
medulloblastoma 10 | 1,524
Pick disease 9 | 1,893
Waldenstrons macroglobulinemia 9 | 765
adrenocortical carcinoma 9 | 1,427
breast carcinoma 9 | 1,614
posterior fossa group B ependymoma 9 | 1,530
cutaneous lupus erythematosus 8 | 1,056
dermatomyositis 8 | 933
nasopharyngeal carcinoma 8 | 1,056
Atopic dermatitis 7 | 944
active Crohn's disease 7 | 918
acute myeloid leukemia 7 | 780
atypical teratoid/rhabdoid tumor 7 | 1,095
esophageal adenocarcinoma 7 | 737
glioblastoma multiforme 7 | 347
hepatocellular carcinoma 7 | 532
juvenile dermatomyositis 7 | 1,189
spina bifida 7 | 1,064
Bladder Neoplasm 6 | 109
Endometriosis 6 | 535
Kidney disease 6 | 396
Mammary Neoplasms 6 | 410
tuberculosis and treatment for 6 months 6 | 686
Autistic Disorder 5 | 320
Intellectual disability 5 | 573
Liver carcinoma 5 | 217
Prostatic Neoplasms 5 | 471
Squamous cell carcinoma 5 | 94
aldosterone-producing adenoma 5 | 664
non primary Sjogren syndrome sicca 5 | 840
sarcoidosis 5 | 358
sonic hedgehog group medulloblastoma 5 | 1,482
Adenocarcinoma 4 | 115
Adenoma 4 | 165
Alzheimer's disease 4 | 644
Amyotrophic Lateral Sclerosis 4 | 431
Barrett's esophagus 4 | 183
Cardiomyopathy 4 | 110
Chronic Lymphocytic Leukemia 4 | 242
Colorectal Neoplasms 4 | 217
Diarrhea 4 | 155
Down syndrome 4 | 548
Immune system cancer 4 | 38
Liver neoplasms 4 | 109
Lung Neoplasms 4 | 171
Melanoma 4 | 261
Osteoporosis 4 | 257
Pancreatic Neoplasm 4 | 79
Pancreatitis 4 | 97
Stomach Neoplasms 4 | 282
Thyroid Neoplasm 4 | 33
fibroadenoma 4 | 557
gastric carcinoma 4 | 832
hereditary spastic paraplegia 4 | 313
non-small cell lung carcinoma 4 | 413
progressive supranuclear palsy 4 | 674

Tissue

Blood and immune system 104 | 17,995
Cardiovascular System 104 | 17,958
Digestive Tract 104 | 18,473
Endocrine System 104 | 18,512
Female tissues 104 | 18,647
Liver and Pancreas 104 | 18,136
Nervous System 104 | 18,561
Respiratory system 104 | 17,484
Urinary Tract 104 | 18,444
Male tissues 103 | 17,969
Skin and soft tissues 103 | 18,115

Target Family

Non-IDG 64 | 11,971
Enzyme 23 | 4,146
Kinase 5 | 634
Transcription Factor 4 | 1,400
Ion Channel 3 | 341
GPCR 2 | 406
Transporter 2 | 473
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Lung cancer cell 104 | 104
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.43192 31.0 94
Protein artemis DCLRE1C Tbio Non-IDG -1.63807 45.4 225
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG 0.27 0.49 34
Akirin-2 AKIRIN2 Tbio Non-IDG -1.20708 20.3 129
T-complex protein 1 subunit epsilon CCT5 Tbio Non-IDG -1.39059 24.5 183
CST complex subunit CTC1 CTC1 Tbio Non-IDG -1.61677 49.3 42