Development Level

Tbio 73 | 11,445
Tchem 16 | 1,598
Tdark 10 | 6,588
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 3 | 220
decreased fasted circulating g... 2 | 65
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
prenatal lethality 2 | 28
preweaning lethality, incomple... 2 | 499
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
convulsive seizures 1 | 13
decreased cardiac muscle contr... 1 | 11
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased coping response 1 | 8
decreased heart left ventricle... 1 | 28
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 67 | 11,493
ovarian cancer 65 | 8,520
osteosarcoma 48 | 7,950
lung cancer 45 | 4,740
psoriasis 44 | 6,694
atypical teratoid / rhabdoid tumor 38 | 5,112
glioblastoma 37 | 5,792
ependymoma 35 | 4,679
medulloblastoma, large-cell 34 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
Breast cancer 30 | 3,578
Cancer 26 | 2,499
malignant mesothelioma 26 | 3,232
group 3 medulloblastoma 24 | 4,104
non-small cell lung cancer 24 | 2,890
oligodendroglioma 24 | 2,850
adult high grade glioma 22 | 3,801
astrocytic glioma 21 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
pancreatic cancer 21 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
invasive ductal carcinoma 20 | 2,951
Astrocytoma, Pilocytic 18 | 3,081
Kidney cancer 18 | 2,613
ductal carcinoma in situ 18 | 1,745
lung adenocarcinoma 17 | 2,716
primitive neuroectodermal tumor 17 | 3,035
Multiple myeloma 16 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Rheumatoid arthritis 15 | 1,191
acute quadriplegic myopathy 15 | 1,158
colon cancer 15 | 1,478
tuberculosis 15 | 2,010
ulcerative colitis 14 | 1,819
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
lung carcinoma 13 | 2,843
subependymal giant cell astrocytoma 13 | 2,287
pituitary cancer 12 | 1,972
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
astrocytoma 10 | 1,146
Autosomal recessive predisposition 9 | 1,442
Epilepsy 9 | 792
Pick disease 9 | 1,894
Waldenstrons macroglobulinemia 9 | 765
adrenocortical carcinoma 9 | 1,428
Kidney disease 8 | 430
Melanoma 8 | 711
cutaneous lupus erythematosus 8 | 1,057
dermatomyositis 8 | 966
hepatocellular carcinoma 8 | 547
nasopharyngeal carcinoma 8 | 1,058
Atopic dermatitis 7 | 952
Short stature 7 | 531
active Crohn's disease 7 | 922
active ulcerative colitis 7 | 764
acute myeloid leukemia 7 | 783
esophageal adenocarcinoma 7 | 737
juvenile dermatomyositis 7 | 1,187
pediatric high grade glioma 7 | 1,064
spina bifida 7 | 1,074
Bladder Neoplasm 6 | 112
Breast Neoplasms 6 | 445
Carcinoma, Hepatocellular 6 | 228
Endometriosis 6 | 540
Intellectual disability 6 | 1,016
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Seizures 6 | 596
Urinary Bladder Neoplasms 6 | 114
non primary Sjogren syndrome sicca 6 | 891
primary pancreatic ductal adenocarcinoma 6 | 1,109
Anemia 5 | 365
Bipolar Disorder 5 | 666
Carcinoma, Squamous Cell 5 | 110
Cardiac Arrhythmia 5 | 103
Cell Transformation, Neoplastic 5 | 97
DOID:9917 5 | 31
Diarrhea 5 | 253
Downward slant of palpebral fissure 5 | 158
Dull intelligence 5 | 645
Endometrial cancer 5 | 311
Ichthyoses 5 | 41
Liver cancer 5 | 604
Liver carcinoma 5 | 240
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Muscle hypotonia 5 | 571
Orbital separation excessive 5 | 244
Palmoplantar keratosis 5 | 74
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Skin cancer 5 | 469
Squamous cell carcinoma 5 | 129
Stomach Neoplasms 5 | 300
aldosterone-producing adenoma 5 | 665
sarcoidosis 5 | 370

Tissue

Skin and soft tissues 102 | 17,230
Digestive Tract 101 | 17,369
Endocrine System 101 | 18,159
Urinary Tract 101 | 16,678
Blood and immune system 100 | 16,909
Female tissues 100 | 17,400
Liver and Pancreas 100 | 16,750
Male tissues 99 | 17,142
Respiratory system 99 | 16,393
Nervous System 98 | 16,725
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 23 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400
Ion Channel 3 | 344
GPCR 2 | 408
Transporter 2 | 473
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Lung cancer cell 103 | 103
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Hypoxia-inducible lipid droplet-associated protein HILPDA Tbio Non-IDG -1.24205 21.6 18
N-acetylated-alpha-linked acidic dipeptidase 2 NAALAD2 Tchem Enzyme -1.51589 30.6 39
Serine/threonine-protein kinase RIO1 RIOK1 Tchem Kinase -0.83569 7.38 159
FXYD domain-containing ion transport regulator 3 FXYD3 Tbio Ion Channel -1.78093 58.4 76
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
tRNA-splicing ligase RtcB homolog RTCB Tbio Enzyme -1.75651 56.6 144
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492