Development Level

Tbio 3,757 | 11,651
Tdark 552 | 6,593
Tchem 533 | 1,388
Tclin 166 | 612

Collection

Kinase: IDG Consortium (Target... 29 | 125
Kinase: IDG Consortium (Comple... 13 | 37
Ion Channel: IDG Consortium (T... 6 | 99
GPCR: IDG Consortium (Complete... 4 | 25
GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, complete... 410 | 979
preweaning lethality, incomple... 172 | 499
embryonic lethality prior to t... 117 | 278
embryonic lethality prior to o... 106 | 239
abnormal behavior 88 | 298
abnormal embryo size 87 | 220
decreased total body fat amoun... 76 | 207
abnormal bone structure 61 | 187
decreased body weight 61 | 161
decreased vertical activity 57 | 208
enlarged heart 55 | 210
increased lean body mass 50 | 172
increased circulating alkaline... 48 | 122
increased startle reflex 47 | 112
decreased circulating choleste... 44 | 93
hypoactivity 43 | 132
abnormal heart morphology 41 | 162
decreased circulating glucose ... 40 | 126
embryonic growth retardation 40 | 106
cataract 39 | 92
hyperactivity 39 | 148
decreased bone mineral content 38 | 151
increased total body fat amoun... 37 | 134
decreased bone mineral density 36 | 126
decreased grip strength 36 | 116
decreased mean corpuscular vol... 36 | 79
abnormal lens morphology 35 | 81
decreased lean body mass 34 | 135
decreased circulating HDL chol... 33 | 68
decreased circulating triglyce... 33 | 79
short tibia 33 | 97
prenatal lethality prior to he... 32 | 87
abnormal seminal vesicle morph... 31 | 114
increased mean corpuscular hem... 31 | 96
male infertility 31 | 123
decreased body length 30 | 101
decreased prepulse inhibition 30 | 82
increased bone mineral content 30 | 108
decreased leukocyte cell numbe... 29 | 73
decreased circulating insulin ... 28 | 76
increased heart weight 28 | 62
abnormal retina morphology 27 | 71
increased or absent threshold ... 27 | 101
decreased circulating serum al... 26 | 82
decreased lymphocyte cell numb... 25 | 83
edema 25 | 59
increased fasted circulating g... 25 | 76
increased mean corpuscular vol... 25 | 92
increased bone mineral density 24 | 72
increased circulating choleste... 24 | 66
small testis 24 | 58
decreased circulating alkaline... 23 | 46
impaired glucose tolerance 23 | 75
improved glucose tolerance 23 | 79
thrombocytopenia 23 | 56
abnormal coat-hair pigmentatio... 22 | 64
abnormal eye morphology 21 | 68
abnormal gait 21 | 69
abnormal neural tube closure 21 | 46
decreased circulating LDL chol... 21 | 38
decreased circulating total pr... 21 | 49
increased circulating HDL chol... 21 | 80
decreased caudal vertebrae num... 20 | 53
decreased erythrocyte cell num... 20 | 62
decreased fasted circulating g... 20 | 65
increased hemoglobin content 20 | 45
small superior vagus ganglion 20 | 74
abnormal behavioral response t... 19 | 66
decreased circulating alanine ... 19 | 47
decreased mean corpuscular hem... 19 | 50
abnormal kidney morphology 18 | 65
abnormal sleep behavior 18 | 70
increased mean platelet volume 18 | 45
decreased blood urea nitrogen ... 17 | 51
decreased hemoglobin content 17 | 68
increased hematocrit 17 | 46
increased leukocyte cell numbe... 17 | 47
abnormal bone mineralization 16 | 38
abnormal testis morphology 16 | 43
enlarged lymph nodes 16 | 37
hydrometra 16 | 53
increased blood urea nitrogen ... 16 | 48
pallor 16 | 34
abnormal skin morphology 15 | 50
decreased circulating calcium ... 15 | 36
decreased neutrophil cell numb... 15 | 42
decreased red blood cell distr... 15 | 41
decreased startle reflex 15 | 75
increased neutrophil cell numb... 15 | 46
persistence of hyaloid vascula... 15 | 33
anophthalmia 14 | 33
increased circulating chloride... 14 | 41
increased circulating iron lev... 14 | 30
increased monocyte cell number 14 | 63
increased prepulse inhibition 14 | 32
tremors 14 | 39
cardiovascular system phenotyp... 13 | 36
increased erythrocyte cell num... 13 | 39
increased mean corpuscular hem... 13 | 36
prolonged QT interval 13 | 38

Disease

Carcinoma 3,419 | 11,493
ovarian cancer 3,097 | 8,520
osteosarcoma 2,522 | 7,950
psoriasis 1,992 | 6,694
medulloblastoma, large-cell 1,824 | 6,241
glioblastoma 1,777 | 5,792
lung cancer 1,664 | 4,740
atypical teratoid / rhabdoid tumor 1,518 | 5,112
ependymoma 1,334 | 4,679
group 3 medulloblastoma 1,150 | 4,104
Breast cancer 1,138 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 1,130 | 3,291
malignant mesothelioma 1,089 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 1,045 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 1,026 | 2,955
adult high grade glioma 1,019 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 1,012 | 2,989
Cancer 1,008 | 2,499
invasive ductal carcinoma 972 | 2,951
Kidney cancer 932 | 2,613
non-small cell lung cancer 891 | 2,890
oligodendroglioma 871 | 2,850
pancreatic cancer 866 | 2,398
lung adenocarcinoma 852 | 2,716
Astrocytoma, Pilocytic 851 | 3,081
primitive neuroectodermal tumor 824 | 3,035
lung carcinoma 797 | 2,843
astrocytic glioma 768 | 2,597
subependymal giant cell astrocytoma 765 | 2,287
Multiple myeloma 692 | 1,332
diabetes mellitus 683 | 1,728
tuberculosis 681 | 2,010
Pick disease 653 | 1,894
interstitial cystitis 626 | 2,312
ulcerative colitis 607 | 1,819
group 4 medulloblastoma 597 | 1,855
Autosomal recessive predisposition 590 | 1,442
breast carcinoma 568 | 1,638
ductal carcinoma in situ 568 | 1,745
acute quadriplegic myopathy 557 | 1,158
astrocytoma 538 | 1,146
pituitary cancer 537 | 1,972
dermatomyositis 530 | 966
juvenile dermatomyositis 516 | 1,187
colon cancer 500 | 1,478
Rheumatoid arthritis 492 | 1,191
cystic fibrosis 474 | 1,696
primary pancreatic ductal adenocarcinoma 457 | 1,109
adrenocortical carcinoma 440 | 1,428
Waldenstrons macroglobulinemia 428 | 765
Intellectual disability 394 | 1,016
Schizophrenia 372 | 1,160
spina bifida 369 | 1,074
pediatric high grade glioma 358 | 1,064
Liver Cirrhosis, Experimental 335 | 769
Epilepsy 328 | 792
cutaneous lupus erythematosus 316 | 1,057
gastric carcinoma 315 | 807
non primary Sjogren syndrome sicca 294 | 891
acute myeloid leukemia 292 | 783
esophageal adenocarcinoma 284 | 737
Duchenne muscular dystrophy 280 | 601
Muscle hypotonia 277 | 571
Atopic dermatitis 276 | 952
Seizures 275 | 596
aldosterone-producing adenoma 275 | 665
Cognitive delay 272 | 608
Global developmental delay 272 | 608
Mental and motor retardation 272 | 608
active Crohn's disease 269 | 922
Dull intelligence 268 | 645
Low intelligence 268 | 645
Mental Retardation 268 | 645
Mental deficiency 268 | 645
Poor school performance 268 | 645
nasopharyngeal carcinoma 259 | 1,058
Obesity 256 | 678
Alzheimer's disease 250 | 658
progressive supranuclear palsy 249 | 676
autosomal dominant Emery-Dreifuss muscular dystrophy 244 | 510
Prostatic Neoplasms 236 | 495
Liver cancer 221 | 604
Down syndrome 219 | 499
active ulcerative colitis 219 | 764
medulloblastoma 219 | 720
primary Sjogren syndrome 211 | 735
Short stature 206 | 531
Neurodegenerative disease 199 | 414
Amyotrophic lateral sclerosis 193 | 451
fibroadenoma 193 | 559
Bipolar Disorder 187 | 666
hepatocellular carcinoma 186 | 547
pancreatic carcinoma 185 | 562
Kidney disease 183 | 430
Melanoma 183 | 711
Breast Neoplasms 180 | 445
Anemia 176 | 365
Mammary Neoplasms 172 | 425
hereditary spastic paraplegia 170 | 318
mucosa-associated lymphoid tissue lymphoma 170 | 484

Tissue

Endocrine System 4,857 | 18,159
Digestive Tract 4,849 | 17,369
Liver and Pancreas 4,848 | 16,750
Female tissues 4,839 | 17,400
Urinary Tract 4,837 | 16,678
Skin and soft tissues 4,835 | 17,230
Male tissues 4,809 | 17,142
Blood and immune system 4,803 | 16,909
Nervous System 4,768 | 16,725
Respiratory system 4,755 | 16,393
Cardiovascular System 4,648 | 15,192

Target Family

Non-IDG 2,852 | 12,091
Enzyme 1,430 | 4,145
Kinase 222 | 634
Transcription Factor 196 | 1,400
Transporter 125 | 473
Epigenetic 104 | 242
Ion Channel 29 | 344
GPCR 23 | 408
Nuclear Receptor 15 | 48
TF/Epigenetic 12 | 38

Jensen-KB Tissue

Liver 5,008 | 5,008
Brain 7,346 | 7,346
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
COP9 signalosome complex subunit 9 COPS9 Tbio Non-IDG 0.21 0.92 14
UDP-glucuronosyltransferase 2B15 UGT2B15 Tbio Enzyme -1.79589 61.5 83
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184