Development Level

Tbio 3,454 | 10,625
Tchem 742 | 1,890
Tdark 628 | 7,003
Tclin 164 | 602

Collection

Eligible Kinase Proteins 32 | 134
Eligible Ion Channel Proteins 6 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 260 | 633
preweaning lethality, incomple... 88 | 260
decreased total body fat amoun... 79 | 186
embryonic lethality prior to t... 76 | 187
abnormal behavior 73 | 226
decreased lean body mass 67 | 195
decreased body weight 66 | 174
embryonic lethality prior to o... 65 | 148
abnormal bone structure 48 | 131
decreased body length 47 | 108
abnormal embryo size 46 | 112
decreased bone mineral content 46 | 157
increased circulating alkaline... 46 | 119
increased or absent threshold ... 40 | 128
abnormal retina morphology 37 | 100
decreased grip strength 37 | 123
increased lean body mass 37 | 107
decreased circulating choleste... 36 | 85
increased mean corpuscular hem... 36 | 93
decreased bone mineral density 35 | 126
decreased circulating HDL chol... 34 | 77
increased bone mineral content 34 | 92
decreased circulating glucose ... 33 | 121
hyperactivity 33 | 108
decreased circulating insulin ... 32 | 75
enlarged heart 31 | 111
abnormal lens morphology 30 | 73
decreased circulating triglyce... 28 | 83
hypoactivity 28 | 89
decreased circulating serum al... 27 | 79
increased mean corpuscular vol... 27 | 91
short tibia 27 | 82
decreased mean corpuscular vol... 26 | 50
prenatal lethality prior to he... 26 | 64
increased grip strength 25 | 83
abnormal bone mineralization 24 | 55
decreased leukocyte cell numbe... 24 | 54
decreased lumbar vertebrae num... 23 | 62
increased fasted circulating g... 22 | 68
decreased circulating LDL chol... 21 | 37
increased exploration in new e... 21 | 56
increased hemoglobin content 21 | 45
abnormal sleep behavior 20 | 63
decreased circulating alkaline... 20 | 41
decreased circulating total pr... 20 | 41
decreased hemoglobin content 20 | 53
increased sacral vertebrae num... 20 | 62
increased bone mineral density 19 | 52
increased circulating choleste... 19 | 53
abnormal neural tube closure 18 | 37
abnormal retinal pigmentation 18 | 61
decreased circulating alanine ... 18 | 53
decreased caudal vertebrae num... 17 | 49
decreased prepulse inhibition 17 | 52
impaired glucose tolerance 17 | 52
improved glucose tolerance 17 | 56
increased circulating HDL chol... 17 | 63
increased heart weight 17 | 37
thrombocytopenia 17 | 46
decreased circulating free fat... 16 | 39
increased body weight 16 | 42
male infertility 16 | 62
abnormal coat/hair pigmentatio... 15 | 54
decreased erythrocyte cell num... 15 | 43
decreased heart weight 15 | 44
decreased neutrophil cell numb... 15 | 37
increased circulating chloride... 15 | 43
increased hematocrit 15 | 36
abnormal cranium morphology 14 | 32
decreased fasted circulating g... 14 | 49
decreased mean corpuscular hem... 14 | 34
decreased rib number 14 | 59
enlarged lymph nodes 14 | 27
abnormal eye morphology 13 | 38
abnormal gait 13 | 51
abnormal heart morphology 13 | 51
abnormal seminal vesicle morph... 13 | 47
decreased threshold for audito... 13 | 32
increased blood urea nitrogen ... 13 | 44
increased circulating sodium l... 13 | 71
increased mean corpuscular hem... 13 | 25
small testis 13 | 37
abnormal behavioral response t... 12 | 52
decreased circulating calcium ... 12 | 33
increased leukocyte cell numbe... 12 | 37
increased startle reflex 12 | 38
abnormal hindbrain development 11 | 24
abnormal testis morphology 11 | 30
cardiovascular system phenotyp... 11 | 35
decreased NK T cell number 11 | 28
decreased blood urea nitrogen ... 11 | 31
decreased circulating fructosa... 11 | 31
increased B cell number 11 | 23
increased circulating phosphat... 11 | 24
increased circulating potassiu... 11 | 31
increased total body fat amoun... 11 | 57
thrombocytosis 11 | 23
tremors 11 | 34
decreased circulating glycerol... 10 | 19
increased erythrocyte cell num... 10 | 26

Disease

ovarian cancer 3,077 | 8,484
osteosarcoma 2,510 | 7,933
psoriasis 1,993 | 6,685
medulloblastoma, large-cell 1,816 | 6,234
glioblastoma 1,694 | 5,572
lung cancer 1,605 | 4,466
atypical teratoid / rhabdoid tumor 1,298 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 1,125 | 3,289
malignant mesothelioma 1,054 | 3,162
intraductal papillary-mucinous adenoma (IPMA) 1,023 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1,011 | 2,988
Breast cancer 1,001 | 3,094
invasive ductal carcinoma 970 | 2,950
Cancer 961 | 2,346
pancreatic ductal adenocarcinoma liver metastasis 958 | 1,795
non-small cell lung cancer 870 | 2,798
oligodendroglioma 870 | 2,849
pilocytic astrocytoma 858 | 3,086
lung adenocarcinoma 848 | 2,713
pancreatic cancer 834 | 2,300
ependymoma 825 | 2,514
primitive neuroectodermal tumor 821 | 3,031
lung carcinoma 795 | 2,844
pediatric high grade glioma 787 | 2,712
subependymal giant cell astrocytoma 766 | 2,287
Carcinoma 741 | 2,147
ulcerative colitis 699 | 2,087
Multiple myeloma 690 | 1,327
diabetes mellitus 670 | 1,663
astrocytic glioma 657 | 2,241
Pick disease 653 | 1,893
astrocytoma 647 | 1,493
group 3 medulloblastoma 638 | 2,254
interstitial cystitis 626 | 2,299
group 4 medulloblastoma 601 | 1,875
adult high grade glioma 584 | 2,148
ductal carcinoma in situ 566 | 1,745
acute quadriplegic myopathy 557 | 1,157
breast carcinoma 554 | 1,614
primary pancreatic ductal adenocarcinoma 540 | 1,271
pituitary cancer 534 | 1,972
tuberculosis 533 | 1,557
juvenile dermatomyositis 516 | 1,189
colon cancer 499 | 1,475
dermatomyositis 495 | 933
Rheumatoid Arthritis 485 | 1,160
cystic fibrosis 460 | 1,665
medulloblastoma 451 | 1,524
adrenocortical carcinoma 440 | 1,427
Waldenstrons macroglobulinemia 429 | 765
sonic hedgehog group medulloblastoma 419 | 1,482
posterior fossa group A ependymoma 407 | 1,511
spina bifida 361 | 1,064
gastric carcinoma 322 | 832
posterior fossa group B ependymoma 319 | 1,530
cutaneous lupus erythematosus 315 | 1,056
atypical teratoid/rhabdoid tumor 313 | 1,095
acute myeloid leukemia 288 | 780
esophageal adenocarcinoma 285 | 737
Duchenne muscular dystrophy 279 | 602
non primary Sjogren syndrome sicca 278 | 840
aldosterone-producing adenoma 275 | 664
Atopic dermatitis 273 | 944
tuberculosis and treatment for 6 months 267 | 686
active Crohn's disease 266 | 918
nasopharyngeal carcinoma 259 | 1,056
progressive supranuclear palsy 250 | 674
autosomal dominant Emery-Dreifuss muscular dystrophy 240 | 499
Alzheimer's disease 236 | 644
Obesity 235 | 616
Down syndrome 230 | 548
primary Sjogren syndrome 228 | 789
Prostatic Neoplasms 226 | 471
Intellectual disability 209 | 573
fibroadenoma 192 | 557
pancreatic carcinoma 188 | 567
Amyotrophic Lateral Sclerosis 186 | 431
Neurodegenerative disease 183 | 383
hepatocellular carcinoma 176 | 532
Kidney disease 171 | 396
IGA Glomerulonephritis 168 | 454
hereditary spastic paraplegia 168 | 313
mucosa-associated lymphoid tissue lymphoma 168 | 480
Mammary Neoplasms 164 | 410
nephrosclerosis 150 | 329
Multiple Sclerosis 146 | 498
Schizophrenia 145 | 501
Endometriosis 133 | 535
Liver disease 128 | 219
Atherosclerosis 127 | 275
Parkinson's disease 127 | 364
gastric cancer 126 | 430
Vascular disease 125 | 281
Polycystic Ovary Syndrome 124 | 332
Stomach Neoplasms 124 | 282
active ulcerative colitis 124 | 477
Liver carcinoma 121 | 217
interstitial lung disease 119 | 291
Anemia 117 | 252
Gaucher disease type 1 115 | 171

Tissue

Digestive Tract 4,885 | 18,473
Liver and Pancreas 4,885 | 18,136
Nervous System 4,881 | 18,561
Female tissues 4,880 | 18,647
Blood and immune system 4,877 | 17,995
Urinary Tract 4,874 | 18,444
Endocrine System 4,871 | 18,512
Cardiovascular System 4,869 | 17,958
Male tissues 4,868 | 17,969
Respiratory system 4,844 | 17,484
Skin and soft tissues 4,835 | 18,115

Target Family

Non-IDG 2,837 | 11,971
Enzyme 1,429 | 4,146
Kinase 221 | 634
Transcription Factor 196 | 1,400
Transporter 125 | 473
Epigenetic 103 | 242
Ion Channel 27 | 341
GPCR 23 | 406
Nuclear Receptor 15 | 48
TF/Epigenetic 12 | 38

Jensen-KB Tissue

Liver 4,988 | 4,988
Brain 7,308 | 7,308
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.46900 2.68 102
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466