Development Level

Tbio 142 | 11,445
Tchem 36 | 1,598
Tclin 15 | 613
Tdark 13 | 6,588

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 5 | 298
abnormal seminal vesicle morph... 5 | 114
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
abnormal vibrissa morphology 4 | 25
decreased bone mineral density 4 | 126
increased bone mineral density 4 | 72
abnormal bone mineralization 3 | 38
decreased body weight 3 | 161
decreased fasted circulating g... 3 | 65
increased circulating choleste... 3 | 66
increased fasted circulating g... 3 | 76
abnormal embryo size 2 | 220
abnormal gait 2 | 69
decreased T cell number 2 | 15
decreased circulating chloride... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating sodium l... 2 | 22
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
enlarged heart 2 | 210
female infertility 2 | 60
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal motor capabilities-co... 1 | 5
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
cataract 1 | 92
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased B cell number 1 | 9
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
lordosis 1 | 1
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
short tibia 1 | 97
stereotypic behavior 1 | 3
trunk curl 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 141 | 11,493
osteosarcoma 113 | 7,950
ovarian cancer 102 | 8,520
psoriasis 80 | 6,694
glioblastoma 76 | 5,792
lung cancer 66 | 4,740
medulloblastoma, large-cell 64 | 6,241
Cancer 62 | 2,499
ependymoma 51 | 4,679
malignant mesothelioma 49 | 3,232
tuberculosis 49 | 2,010
lung carcinoma 47 | 2,843
adult high grade glioma 46 | 3,801
interstitial cystitis 46 | 2,312
atypical teratoid / rhabdoid tumor 44 | 5,112
pancreatic cancer 44 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
Astrocytoma, Pilocytic 42 | 3,081
non-small cell lung cancer 42 | 2,890
invasive ductal carcinoma 41 | 2,951
ulcerative colitis 39 | 1,819
Rheumatoid arthritis 38 | 1,191
lung adenocarcinoma 38 | 2,716
Breast cancer 37 | 3,578
group 3 medulloblastoma 36 | 4,104
Autosomal recessive predisposition 34 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
subependymal giant cell astrocytoma 33 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
cutaneous lupus erythematosus 29 | 1,057
primitive neuroectodermal tumor 29 | 3,035
diabetes mellitus 28 | 1,728
pituitary cancer 27 | 1,972
cystic fibrosis 26 | 1,696
Multiple Sclerosis 25 | 540
astrocytoma 25 | 1,146
juvenile dermatomyositis 25 | 1,187
Asthma 23 | 385
ductal carcinoma in situ 22 | 1,745
mucosa-associated lymphoid tissue lymphoma 22 | 484
oligodendroglioma 22 | 2,850
primary Sjogren syndrome 22 | 735
astrocytic glioma 21 | 2,597
breast carcinoma 21 | 1,638
Prostatic Neoplasms 20 | 495
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Kidney cancer 19 | 2,613
Liver Cirrhosis, Experimental 19 | 769
Schizophrenia 19 | 1,160
Hypersensitivity reaction type II disease 18 | 253
gastric carcinoma 18 | 807
Kidney disease 17 | 430
group 4 medulloblastoma 17 | 1,855
Bipolar Disorder 16 | 666
Intellectual disability 16 | 1,016
Multiple myeloma 16 | 1,332
Pick disease 16 | 1,894
Seizures 16 | 596
active ulcerative colitis 16 | 764
colon cancer 16 | 1,478
non primary Sjogren syndrome sicca 16 | 891
pancreatic carcinoma 16 | 562
Atherosclerosis 15 | 291
Vasculitis 15 | 80
Waldenstrons macroglobulinemia 15 | 765
acute quadriplegic myopathy 15 | 1,158
adrenocortical carcinoma 15 | 1,428
dermatomyositis 15 | 966
sarcoidosis 15 | 370
Cognitive delay 14 | 608
Epilepsy 14 | 792
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
esophageal adenocarcinoma 14 | 737
hepatocellular carcinoma 14 | 547
spina bifida 14 | 1,074
Arthritis 13 | 290
Atopic dermatitis 13 | 952
Crohn's disease 13 | 321
Stomach Neoplasms 13 | 300
fibroadenoma 13 | 559
Alzheimer's disease 12 | 658
Coronary artery disease 12 | 268
Diarrhea 12 | 253
Dull intelligence 12 | 645
Liver disease 12 | 237
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Muscle hypotonia 12 | 571
Neurodegenerative disease 12 | 414
Obesity 12 | 678
Poor school performance 12 | 645
pediatric high grade glioma 12 | 1,064
primary pancreatic ductal adenocarcinoma 12 | 1,109
Anemia 11 | 365
Hypertension 11 | 396
Major Depressive Disorder 11 | 301
gastric cancer 11 | 459
periodontitis 11 | 293

Tissue

Endocrine System 199 | 18,159
Blood and immune system 197 | 16,909
Digestive Tract 197 | 17,369
Liver and Pancreas 196 | 16,750
Urinary Tract 196 | 16,678
Female tissues 195 | 17,400
Skin and soft tissues 195 | 17,230
Male tissues 194 | 17,142
Nervous System 193 | 16,725
Respiratory system 192 | 16,393
Cardiovascular System 185 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 50 | 4,145
Kinase 12 | 634
GPCR 11 | 408
Transcription Factor 8 | 1,400
Ion Channel 3 | 344
Transporter 3 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Leukocyte 206 | 206
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-18-binding protein IL18BP Tbio Non-IDG -2.00596 101.6 307
Alpha-(1,3)-fucosyltransferase 5 FUT5 Tbio Enzyme -1.52044 31.5 32
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
LIM domain only protein 7 LMO7 Tbio Non-IDG -1.24771 19.7 80
Anoctamin-10 ANO10 Tbio Non-IDG -1.22069 14.6 54
E3 ubiquitin-protein ligase TRIM39 TRIM39 Tbio Enzyme -1.24729 16.2 194
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Krueppel-like factor 6 KLF6 Tbio Transcription Factor -2.37304 253.6 161