Development Level

Tbio 863 | 11,178
Tdark 195 | 6,569
Tchem 179 | 1,885
Tclin 62 | 612

Collection

Ion Channel: IDG Consortium (T... 12 | 99
Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 93 | 979
preweaning lethality, incomple... 46 | 499
abnormal behavior 28 | 298
abnormal embryo size 24 | 220
embryonic lethality prior to t... 24 | 278
enlarged heart 21 | 210
decreased total body fat amoun... 20 | 207
embryonic lethality prior to o... 19 | 239
decreased vertical activity 18 | 208
increased lean body mass 18 | 172
abnormal bone structure 17 | 187
decreased body weight 17 | 161
decreased bone mineral content 17 | 151
abnormal heart morphology 15 | 162
increased total body fat amoun... 14 | 134
decreased bone mineral density 13 | 126
decreased lean body mass 13 | 135
decreased prepulse inhibition 13 | 82
hypoactivity 13 | 132
increased circulating alkaline... 13 | 122
decreased grip strength 12 | 116
decreased circulating glucose ... 11 | 126
decreased hemoglobin content 11 | 68
increased mean corpuscular vol... 11 | 92
male infertility 11 | 123
abnormal retina morphology 10 | 71
hyperactivity 10 | 148
abnormal eye morphology 9 | 68
decreased circulating insulin ... 9 | 76
decreased circulating triglyce... 9 | 79
embryonic growth retardation 9 | 106
increased bone mineral density 9 | 72
increased circulating HDL chol... 9 | 80
increased or absent threshold ... 9 | 101
increased startle reflex 9 | 112
thrombocytopenia 9 | 56
abnormal skin morphology 8 | 50
decreased circulating choleste... 8 | 93
decreased lymphocyte cell numb... 8 | 83
enlarged spleen 8 | 41
improved glucose tolerance 8 | 79
increased bone mineral content 8 | 108
increased mean corpuscular hem... 8 | 96
short tibia 8 | 97
small testis 8 | 58
abnormal gait 7 | 69
abnormal kidney morphology 7 | 65
abnormal seminal vesicle morph... 7 | 114
cataract 7 | 92
decreased erythrocyte cell num... 7 | 62
decreased mean corpuscular vol... 7 | 79
decreased startle reflex 7 | 75
increased fasted circulating g... 7 | 76
prenatal lethality prior to he... 7 | 87
tremors 7 | 39
abnormal epididymis morphology 6 | 42
abnormal lens morphology 6 | 81
abnormal neural tube closure 6 | 46
abnormal testis morphology 6 | 43
decreased body length 6 | 101
decreased leukocyte cell numbe... 6 | 73
impaired glucose tolerance 6 | 75
increased blood urea nitrogen ... 6 | 48
increased circulating chloride... 6 | 41
increased circulating creatini... 6 | 38
increased leukocyte cell numbe... 6 | 47
prolonged ST segment 6 | 36
abnormal bone mineralization 5 | 38
abnormal coat-hair pigmentatio... 5 | 64
abnormal startle reflex 5 | 15
anophthalmia 5 | 33
decreased circulating HDL chol... 5 | 68
decreased circulating alanine ... 5 | 47
decreased circulating fructosa... 5 | 30
decreased circulating serum al... 5 | 82
decreased circulating total pr... 5 | 49
decreased eosinophil cell numb... 5 | 24
decreased hematocrit 5 | 46
decreased mean corpuscular hem... 5 | 50
increased circulating choleste... 5 | 66
increased red blood cell distr... 5 | 34
prolonged QT interval 5 | 38
small superior vagus ganglion 5 | 74
abnormal cornea morphology 4 | 31
abnormal sleep behavior 4 | 70
abnormal spleen morphology 4 | 55
decreased circulating alkaline... 4 | 46
decreased circulating bilirubi... 4 | 19
decreased circulating creatini... 4 | 39
decreased fasted circulating g... 4 | 65
decreased neutrophil cell numb... 4 | 42
decreased red blood cell distr... 4 | 41
increased circulating potassiu... 4 | 29
increased heart weight 4 | 62
increased hematocrit 4 | 46
increased hemoglobin content 4 | 45
microphthalmia 4 | 26
pale yolk sac 4 | 25
pallor 4 | 34
thrombocytosis 4 | 27

Disease

Carcinoma 799 | 11,192
ovarian cancer 675 | 8,297
osteosarcoma 579 | 7,766
psoriasis 473 | 6,514
medulloblastoma, large-cell 457 | 6,086
glioblastoma 431 | 5,635
atypical teratoid / rhabdoid tumor 372 | 4,971
lung cancer 354 | 4,607
ependymoma 322 | 4,559
group 3 medulloblastoma 285 | 4,002
malignant mesothelioma 272 | 3,135
intraductal papillary-mucinous neoplasm (IPMN) 267 | 3,204
Breast cancer 259 | 3,469
adult high grade glioma 258 | 3,701
intraductal papillary-mucinous adenoma (IPMA) 250 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 247 | 2,902
invasive ductal carcinoma 240 | 2,867
non-small cell lung cancer 229 | 2,799
oligodendroglioma 218 | 2,768
Astrocytoma, Pilocytic 213 | 3,006
lung adenocarcinoma 213 | 2,627
primitive neuroectodermal tumor 208 | 2,957
lung carcinoma 206 | 2,755
pancreatic cancer 204 | 2,322
astrocytic glioma 190 | 2,530
Cancer 189 | 2,388
pancreatic ductal adenocarcinoma liver metastasis 186 | 1,911
interstitial cystitis 175 | 2,237
subependymal giant cell astrocytoma 173 | 2,230
Autosomal recessive predisposition 159 | 1,407
ductal carcinoma in situ 157 | 1,686
Pick disease 156 | 1,856
Kidney cancer 155 | 2,548
ulcerative colitis 155 | 1,765
pituitary cancer 152 | 1,915
tuberculosis 144 | 1,963
cystic fibrosis 143 | 1,629
breast carcinoma 128 | 1,589
group 4 medulloblastoma 127 | 1,806
Multiple myeloma 123 | 1,296
adrenocortical carcinoma 118 | 1,385
diabetes mellitus 116 | 1,683
colon cancer 110 | 1,428
primary pancreatic ductal adenocarcinoma 102 | 1,071
Intellectual disability 98 | 998
astrocytoma 94 | 1,113
pediatric high grade glioma 90 | 1,035
Schizophrenia 88 | 1,136
Epilepsy 87 | 775
juvenile dermatomyositis 86 | 1,147
acute quadriplegic myopathy 83 | 1,133
spina bifida 82 | 1,053
Kidney disease 79 | 411
dermatomyositis 77 | 941
nephrosclerosis 76 | 314
Dull intelligence 73 | 634
Liver Cirrhosis, Experimental 73 | 733
Low intelligence 73 | 634
Mental Retardation 73 | 634
Mental deficiency 73 | 634
Poor school performance 73 | 634
Rheumatoid arthritis 72 | 1,156
active ulcerative colitis 72 | 736
gastric carcinoma 71 | 781
Seizures 69 | 584
active Crohn's disease 69 | 882
Cognitive delay 67 | 596
Global developmental delay 67 | 596
Mental and motor retardation 67 | 596
cutaneous lupus erythematosus 67 | 1,016
esophageal adenocarcinoma 65 | 696
non primary Sjogren syndrome sicca 65 | 861
Hypertension 61 | 372
Atopic dermatitis 60 | 915
Waldenstrons macroglobulinemia 59 | 742
Muscle hypotonia 58 | 562
nasopharyngeal carcinoma 57 | 1,024
pancreatic carcinoma 54 | 555
Bipolar Disorder 53 | 646
Prostatic Neoplasms 53 | 472
progressive supranuclear palsy 53 | 656
acute myeloid leukemia 51 | 760
fibroadenoma 49 | 538
Duchenne muscular dystrophy 48 | 587
Multiple Sclerosis 48 | 527
Obesity 48 | 655
Short stature 47 | 514
Alzheimer's disease 46 | 640
Melanoma 46 | 689
medulloblastoma 46 | 702
Endometriosis 44 | 521
primary Sjogren syndrome 44 | 710
Failure to gain weight 43 | 359
Pediatric failure to thrive 43 | 359
aldosterone-producing adenoma 43 | 646
Down syndrome 42 | 480
mucosa-associated lymphoid tissue lymphoma 42 | 473
posterior fossa group A ependymoma 42 | 456
sonic hedgehog group medulloblastoma 41 | 459
autosomal dominant Emery-Dreifuss muscular dystrophy 40 | 492

Tissue

Urinary Tract 1,275 | 16,678
Endocrine System 1,272 | 18,159
Digestive Tract 1,265 | 17,369
Male tissues 1,258 | 17,142
Skin and soft tissues 1,257 | 17,230
Female tissues 1,255 | 17,400
Nervous System 1,248 | 16,725
Liver and Pancreas 1,246 | 16,750
Blood and immune system 1,231 | 16,909
Respiratory system 1,220 | 16,393
Cardiovascular System 1,150 | 15,192

Target Family

Non-IDG 658 | 12,091
Enzyme 370 | 4,145
Transporter 86 | 473
Transcription Factor 59 | 1,400
Kinase 44 | 634
Ion Channel 35 | 344
GPCR 21 | 408
Nuclear Receptor 14 | 48
Epigenetic 10 | 242
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Kidney 1,299 | 1,299
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
Docking protein 5 DOK5 Tbio Non-IDG -1.04456 11.4 284
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199
Putative cytochrome b-c1 complex subunit Rieske-like protein 1 UQCRFS1P1 Tdark Non-IDG -2.12377 231.9 0
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113
Serine/threonine-protein kinase N1 PKN1 Tchem Kinase -2.03368 117.6 153
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
C-Jun-amino-terminal kinase-interacting protein 4 SPAG9 Tbio Enzyme -2.45490 258.6 149