Development Level

Tbio 109 | 11,651
Tchem 15 | 1,388
Tdark 10 | 6,593
Tclin 5 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 3 | 151
decreased neutrophil cell numb... 3 | 42
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 31
decreased vertical activity 2 | 208
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
abnormal QT variability 1 | 10
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
narrow eye opening 1 | 12
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
protruding tongue 1 | 3
small kidney 1 | 16

Disease

ovarian cancer 76 | 8,520
Carcinoma 74 | 11,493
psoriasis 74 | 6,694
osteosarcoma 56 | 7,950
glioblastoma 55 | 5,792
lung cancer 54 | 4,740
medulloblastoma, large-cell 50 | 6,241
Cancer 48 | 2,499
Breast cancer 44 | 3,578
atypical teratoid / rhabdoid tumor 44 | 5,112
ependymoma 43 | 4,679
non-small cell lung cancer 39 | 2,890
adult high grade glioma 37 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
interstitial cystitis 33 | 2,312
pancreatic cancer 33 | 2,398
malignant mesothelioma 32 | 3,232
group 3 medulloblastoma 30 | 4,104
lung carcinoma 30 | 2,843
cystic fibrosis 29 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
lung adenocarcinoma 28 | 2,716
esophageal adenocarcinoma 27 | 737
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
Astrocytoma, Pilocytic 26 | 3,081
acute quadriplegic myopathy 24 | 1,158
colon cancer 24 | 1,478
invasive ductal carcinoma 24 | 2,951
astrocytic glioma 23 | 2,597
juvenile dermatomyositis 23 | 1,187
nasopharyngeal carcinoma 23 | 1,058
oligodendroglioma 23 | 2,850
cutaneous lupus erythematosus 22 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
Kidney cancer 21 | 2,613
Multiple myeloma 20 | 1,332
ductal carcinoma in situ 20 | 1,745
primitive neuroectodermal tumor 20 | 3,035
spina bifida 20 | 1,074
tuberculosis 20 | 2,010
Autosomal recessive predisposition 19 | 1,442
breast carcinoma 19 | 1,638
dermatomyositis 19 | 966
diabetes mellitus 18 | 1,728
subependymal giant cell astrocytoma 18 | 2,287
Atopic dermatitis 17 | 952
active Crohn's disease 17 | 922
active ulcerative colitis 17 | 764
group 4 medulloblastoma 17 | 1,855
Pick disease 14 | 1,894
Waldenstrons macroglobulinemia 14 | 765
Liver Cirrhosis, Experimental 13 | 769
Schizophrenia 13 | 1,160
Duchenne muscular dystrophy 12 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
non primary Sjogren syndrome sicca 12 | 891
pituitary cancer 12 | 1,972
Dermatitis 11 | 157
Intellectual disability 11 | 1,016
astrocytoma 11 | 1,146
ulcerative colitis 11 | 1,819
Prostatic Neoplasms 10 | 495
mucosa-associated lymphoid tissue lymphoma 10 | 484
Melanoma 9 | 711
adrenocortical carcinoma 9 | 1,428
primary pancreatic ductal adenocarcinoma 9 | 1,109
Dull intelligence 8 | 645
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Palmoplantar keratosis 8 | 74
Poor school performance 8 | 645
Skin cancer 8 | 469
Squamous cell carcinoma 8 | 129
chronic lymphosyte leukemia 8 | 204
primary Sjogren syndrome 8 | 735
progressive supranuclear palsy 8 | 676
Abnormal blistering of the skin 7 | 54
Blister of skin 7 | 54
Breast Neoplasms 7 | 445
Carcinoma, Squamous Cell 7 | 110
Defective enamel matrix 7 | 35
Dental Enamel Hypoplasia 7 | 43
Dental caries 7 | 164
Dysplasia of tooth enamel 7 | 35
Dystrophia unguium 7 | 53
Mammary Neoplasms 7 | 425
Rheumatoid arthritis 7 | 1,191
Rotting teeth 7 | 73
Skin bulla 7 | 54
Thin dental enamel 7 | 35
cystic fibrosis and chronic rhinosinusitis 7 | 214
pediatric high grade glioma 7 | 1,064
sarcoidosis 7 | 370
Becker muscular dystrophy 6 | 191
Down syndrome 6 | 499
Endometriosis 6 | 540
Muscle hypotonia 6 | 571
aldosterone-producing adenoma 6 | 665

Tissue

Blood and immune system 136 | 16,909
Digestive Tract 135 | 17,369
Female tissues 135 | 17,400
Skin and soft tissues 135 | 17,230
Endocrine System 132 | 18,159
Urinary Tract 130 | 16,678
Liver and Pancreas 129 | 16,750
Male tissues 127 | 17,142
Respiratory system 122 | 16,393
Cardiovascular System 117 | 15,192
Nervous System 117 | 16,725

Target Family

Non-IDG 97 | 12,091
Enzyme 30 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Ion Channel 2 | 344
Transporter 1 | 473

Jensen-KB Tissue

Keratinocyte 139 | 139
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratinocyte-associated protein 2 KRTCAP2 Tbio Non-IDG -0.67158 5.41 59
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Desmocollin-2 DSC2 Tbio Non-IDG -1.89689 79.7 173
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
Guanine nucleotide exchange factor VAV3 VAV3 Tbio Non-IDG -1.82116 74.0 249
Heterogeneous nuclear ribonucleoprotein H HNRNPH1 Tbio Non-IDG -1.71562 50.9 205
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.06798 109.1 482
Stress-induced-phosphoprotein 1 STIP1 Tbio Non-IDG -2.00823 110.8 293
14-3-3 protein sigma SFN Tbio Non-IDG -2.56638 391.2 550
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778