Development Level

Tbio 101 | 10,625
Tchem 22 | 1,890
Tdark 12 | 7,003
Tclin 5 | 602

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
decreased circulating serum al... 2 | 79
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased leukocyte cell numbe... 2 | 37
increased or absent threshold ... 2 | 128
increased red blood cell distr... 2 | 21
abnormal behavior 1 | 226
abnormal body wall morphology 1 | 7
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
cataract 1 | 26
corneal opacity 1 | 25
corneal vascularization 1 | 5
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lymphocyte cell numb... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased startle reflex 1 | 48
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating glycerol... 1 | 11
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased lean body mass 1 | 107
increased neutrophil cell numb... 1 | 15
increased urine magnesium leve... 1 | 1
male infertility 1 | 62
narrow eye opening 1 | 15
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
protruding tongue 1 | 1

Disease

ovarian cancer 75 | 8,484
psoriasis 75 | 6,685
osteosarcoma 56 | 7,933
glioblastoma 55 | 5,572
lung cancer 52 | 4,466
medulloblastoma, large-cell 50 | 6,234
Cancer 46 | 2,346
Breast cancer 39 | 3,094
atypical teratoid / rhabdoid tumor 39 | 4,369
non-small cell lung cancer 38 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,289
interstitial cystitis 33 | 2,299
pancreatic cancer 33 | 2,300
lung carcinoma 30 | 2,844
malignant mesothelioma 30 | 3,162
cystic fibrosis 29 | 1,665
esophageal adenocarcinoma 28 | 737
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,988
lung adenocarcinoma 28 | 2,713
ependymoma 27 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
pilocytic astrocytoma 26 | 3,086
acute quadriplegic myopathy 24 | 1,157
adult high grade glioma 24 | 2,148
colon cancer 24 | 1,475
invasive ductal carcinoma 24 | 2,950
juvenile dermatomyositis 23 | 1,189
nasopharyngeal carcinoma 23 | 1,056
oligodendroglioma 23 | 2,849
ulcerative colitis 23 | 2,087
cutaneous lupus erythematosus 22 | 1,056
Carcinoma 20 | 2,147
Multiple myeloma 20 | 1,327
ductal carcinoma in situ 20 | 1,745
pediatric high grade glioma 20 | 2,712
primitive neuroectodermal tumor 20 | 3,031
spina bifida 20 | 1,064
astrocytic glioma 19 | 2,241
breast carcinoma 19 | 1,614
dermatomyositis 19 | 933
group 3 medulloblastoma 19 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
diabetes mellitus 18 | 1,663
subependymal giant cell astrocytoma 18 | 2,287
Atopic dermatitis 17 | 944
active Crohn's disease 17 | 918
medulloblastoma 17 | 1,524
tuberculosis 16 | 1,557
astrocytoma 15 | 1,493
Pick disease 14 | 1,893
Waldenstrons macroglobulinemia 14 | 765
posterior fossa group A ependymoma 14 | 1,511
Duchenne muscular dystrophy 12 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 499
pituitary cancer 12 | 1,972
primary pancreatic ductal adenocarcinoma 12 | 1,271
Dermatitis 11 | 107
primary Sjogren syndrome 11 | 789
Prostatic Neoplasms 10 | 471
group 4 medulloblastoma 10 | 1,875
mucosa-associated lymphoid tissue lymphoma 10 | 480
adrenocortical carcinoma 9 | 1,427
atypical teratoid/rhabdoid tumor 9 | 1,095
non primary Sjogren syndrome sicca 9 | 840
sonic hedgehog group medulloblastoma 9 | 1,482
IGA Glomerulonephritis 8 | 454
chronic lymphosyte leukemia 8 | 232
progressive supranuclear palsy 8 | 674
Mammary Neoplasms 7 | 410
Squamous cell carcinoma 7 | 94
sarcoidosis 7 | 358
Animal Mammary Neoplasms 6 | 136
Becker muscular dystrophy 6 | 187
Down syndrome 6 | 548
Endometriosis 6 | 535
Epidermolysis bullosa 6 | 21
Mammary Neoplasms, Experimental 6 | 150
Rheumatoid Arthritis 6 | 1,160
Schizophrenia 6 | 501
active ulcerative colitis 6 | 477
aldosterone-producing adenoma 6 | 664
cystic fibrosis and chronic rhinosinusitis 6 | 213
non-small cell lung carcinoma 6 | 413
posterior fossa group B ependymoma 6 | 1,530
tuberculosis and treatment for 6 months 6 | 686
Amyotrophic Lateral Sclerosis 5 | 431
Asthma 5 | 349
Barrett's esophagus 5 | 183
Epidermolytic hyperkeratosis 5 | 13
Hypersensitivity reaction type II disease 5 | 235
Multiple Sclerosis 5 | 498
Myocardial Ischemia 5 | 169
Neoplasm Invasiveness 5 | 127
Neoplasm Metastasis 5 | 138
Netherton syndrome 5 | 14
acute myeloid leukemia 5 | 780
gastric carcinoma 5 | 832
hereditary spastic paraplegia 5 | 313
inflammatory breast cancer 5 | 404
periodontitis 5 | 269

Tissue

Female tissues 137 | 18,647
Blood and immune system 136 | 17,995
Digestive Tract 136 | 18,473
Endocrine System 136 | 18,512
Nervous System 136 | 18,561
Skin and soft tissues 136 | 18,115
Urinary Tract 136 | 18,444
Liver and Pancreas 135 | 18,136
Cardiovascular System 134 | 17,958
Male tissues 134 | 17,969
Respiratory system 134 | 17,484

Target Family

Non-IDG 98 | 11,971
Enzyme 30 | 4,146
Kinase 4 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 406
Ion Channel 2 | 341
Transporter 1 | 473

Jensen-KB Tissue

Keratinocyte 140 | 140
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calumenin CALU Tbio Non-IDG -1.76431 61.4 157
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.21530 0.00000 460
Elongation factor 1-beta EEF1B2 Tbio Non-IDG -1.77658 56.5 100
Cornifin-A SPRR1A Tbio Non-IDG -1.15694 13.4 60
C-X-C motif chemokine 9 CXCL9 Tbio Non-IDG -2.88793 860.6 317
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.98787 974.3 154
Keratin, type I cytoskeletal 10 KRT10 Tbio Non-IDG -2.80444 621.7 603
Translationally-controlled tumor protein TPT1 Tbio Non-IDG -2.70459 550.0 375
Integrin alpha-6 ITGA6 Tchem Non-IDG -2.25486 168.8 756
Kallikrein-7 KLK7 Tchem Enzyme -2.07784 133.2 260