Development Level

Tbio 127 | 11,178
Tchem 47 | 1,885
Tclin 13 | 612
Tdark 5 | 6,569

IMPC Phenotype

preweaning lethality, complete... 20 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 6 | 499
decreased circulating choleste... 5 | 93
decreased total body fat amoun... 5 | 207
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased vertical activity 4 | 208
hyperactivity 4 | 148
increased lean body mass 4 | 172
short tibia 4 | 97
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
absent startle reflex 2 | 24
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
embryonic growth retardation 2 | 106
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased fasted circulating g... 2 | 76
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
absent pinna reflex 1 | 23
anophthalmia 1 | 33
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgM level 1 | 1
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small spleen 1 | 19
syndactyly 1 | 23

Disease

ovarian cancer 138 | 8,297
Carcinoma 112 | 11,192
lung cancer 81 | 4,607
psoriasis 80 | 6,514
glioblastoma 75 | 5,635
medulloblastoma, large-cell 74 | 6,086
osteosarcoma 71 | 7,766
Cancer 70 | 2,388
Multiple myeloma 66 | 1,296
atypical teratoid / rhabdoid tumor 63 | 4,971
ependymoma 61 | 4,559
group 3 medulloblastoma 51 | 4,002
Breast cancer 47 | 3,469
adult high grade glioma 44 | 3,701
pancreatic cancer 44 | 2,322
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,204
diabetes mellitus 41 | 1,683
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,902
Waldenstrons macroglobulinemia 40 | 742
astrocytic glioma 39 | 2,530
invasive ductal carcinoma 39 | 2,867
oligodendroglioma 39 | 2,768
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,911
lung adenocarcinoma 38 | 2,627
non-small cell lung cancer 38 | 2,799
primitive neuroectodermal tumor 35 | 2,957
malignant mesothelioma 34 | 3,135
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,872
Astrocytoma, Pilocytic 31 | 3,006
acute quadriplegic myopathy 29 | 1,133
breast carcinoma 29 | 1,589
Pick disease 28 | 1,856
lung carcinoma 28 | 2,755
Autosomal recessive predisposition 27 | 1,407
Schizophrenia 27 | 1,136
primary pancreatic ductal adenocarcinoma 27 | 1,071
Alzheimer's disease 24 | 640
subependymal giant cell astrocytoma 24 | 2,230
astrocytoma 23 | 1,113
cystic fibrosis 23 | 1,629
group 4 medulloblastoma 23 | 1,806
ulcerative colitis 23 | 1,765
Carcinoma, Hepatocellular 22 | 217
Breast Neoplasms 21 | 423
Liver carcinoma 21 | 229
Mammary Neoplasms 21 | 403
Stomach Neoplasms 21 | 287
colon cancer 21 | 1,428
dermatomyositis 21 | 941
Epilepsy 20 | 775
Muscle hypotonia 20 | 562
Rheumatoid arthritis 20 | 1,156
pituitary cancer 20 | 1,915
tuberculosis 20 | 1,963
juvenile dermatomyositis 19 | 1,147
Neurodegenerative disease 17 | 402
Osteoporosis 17 | 348
Cognitive delay 16 | 596
Duchenne muscular dystrophy 16 | 587
Global developmental delay 16 | 596
Mammary Neoplasms, Experimental 16 | 147
Mental and motor retardation 16 | 596
Seizures 16 | 584
non primary Sjogren syndrome sicca 16 | 861
Amyotrophic lateral sclerosis 15 | 437
Animal Mammary Neoplasms 15 | 130
Mammary Neoplasms, Animal 15 | 130
Neoplasm Invasiveness 15 | 151
Parkinson's disease 15 | 378
Prostatic Neoplasms 15 | 472
pediatric high grade glioma 15 | 1,035
Bipolar Disorder 14 | 646
Intellectual disability 14 | 998
Liver Cirrhosis, Experimental 14 | 733
Neoplasm Metastasis 14 | 160
Vascular disease 14 | 294
adrenocortical carcinoma 14 | 1,385
interstitial cystitis 14 | 2,237
Acute coronary syndrome 13 | 37
HIV Infections 13 | 94
Nystagmus 13 | 309
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 492
ductal carcinoma in situ 13 | 1,686
Adenocarcinoma of lung 12 | 140
Atopic dermatitis 12 | 915
Degenerative polyarthritis 12 | 110
Osteoarthritis 12 | 179
Cerebellar Ataxia 11 | 302
Chemical and Drug Induced Liver Injury 11 | 188
Down syndrome 11 | 480
Hypertension 11 | 372
Kidney cancer 11 | 2,548
Kidney disease 11 | 411
acute myeloid leukemia 11 | 760
nasopharyngeal carcinoma 11 | 1,024
non-small cell lung carcinoma 11 | 302
spina bifida 11 | 1,053
Disease Progression 10 | 133
aldosterone-producing adenoma 10 | 646
gastric carcinoma 10 | 781

Tissue

Endocrine System 190 | 18,159
Digestive Tract 189 | 17,369
Female tissues 189 | 17,400
Liver and Pancreas 189 | 16,750
Male tissues 189 | 17,142
Skin and soft tissues 189 | 17,230
Nervous System 188 | 16,725
Blood and immune system 187 | 16,909
Respiratory system 186 | 16,393
Urinary Tract 186 | 16,678
Cardiovascular System 184 | 15,192

Target Family

Non-IDG 110 | 12,091
Enzyme 74 | 4,145
Kinase 6 | 634
Epigenetic 2 | 242

Jensen-KB Tissue

Interstitial cell of Cajal 192 | 192
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inorganic pyrophosphatase PPA1 Tbio Enzyme -2.82678 691.2 169
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
Chromobox protein homolog 1 CBX1 Tbio Epigenetic -2.31837 203.1 260
Coactosin-like protein COTL1 Tbio Non-IDG -1.29261 19.3 205
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79
Phosphatidylethanolamine-binding protein 1 PEBP1 Tbio Non-IDG -2.62467 484.3 511
Peroxiredoxin-6 PRDX6 Tbio Non-IDG -2.63290 435.3 425
ES1 protein homolog, mitochondrial C21orf33 Tbio Non-IDG -2.41700 243.3 112
Flavin reductase (NADPH) BLVRB Tbio Enzyme -2.31527 194.9 246
Alpha-enolase ENO1 Tchem Enzyme -2.83087 656.7 508