Development Level

Tbio 126 | 10,625
Tchem 47 | 1,890
Tclin 14 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 8 | 633
decreased body weight 6 | 174
embryonic lethality prior to t... 5 | 187
abnormal behavior 4 | 226
decreased total body fat amoun... 4 | 186
embryonic lethality prior to o... 4 | 148
increased lean body mass 3 | 107
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal coat/hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased lean body mass 2 | 195
hyperactivity 2 | 108
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased mean corpuscular hem... 2 | 93
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal retinal outer nuclear... 1 | 5
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal startle reflex 1 | 14
abnormal tail movements 1 | 12
abnormal vitreous body morphol... 1 | 7
absent startle reflex 1 | 15
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased IgM level 1 | 1
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating sodium l... 1 | 18
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased lumbar vertebrae num... 1 | 62
decreased startle reflex 1 | 48
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
microphthalmia 1 | 15
small spleen 1 | 11
thrombocytopenia 1 | 46

Disease

ovarian cancer 146 | 8,492
lung cancer 86 | 4,473
psoriasis 86 | 6,685
glioblastoma 78 | 5,572
medulloblastoma, large-cell 77 | 6,234
Multiple myeloma 74 | 1,328
osteosarcoma 74 | 7,933
Cancer 69 | 2,346
atypical teratoid / rhabdoid tumor 56 | 4,369
Breast cancer 49 | 3,099
ependymoma 45 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,289
pancreatic cancer 45 | 2,300
diabetes mellitus 44 | 1,663
Waldenstrons macroglobulinemia 43 | 765
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
invasive ductal carcinoma 41 | 2,950
oligodendroglioma 41 | 2,849
lung adenocarcinoma 40 | 2,714
non-small cell lung cancer 39 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,795
pediatric high grade glioma 37 | 2,712
primitive neuroectodermal tumor 37 | 3,031
astrocytic glioma 34 | 2,241
pilocytic astrocytoma 33 | 3,086
astrocytoma 32 | 1,493
group 3 medulloblastoma 32 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
malignant mesothelioma 32 | 3,163
acute quadriplegic myopathy 31 | 1,157
ulcerative colitis 30 | 2,087
Pick disease 29 | 1,893
breast carcinoma 29 | 1,614
lung carcinoma 29 | 2,844
primary pancreatic ductal adenocarcinoma 29 | 1,271
Alzheimer's disease 25 | 644
adult high grade glioma 25 | 2,148
subependymal giant cell astrocytoma 25 | 2,287
cystic fibrosis 23 | 1,670
colon cancer 22 | 1,475
dermatomyositis 22 | 967
Liver carcinoma 21 | 217
Mammary Neoplasms 21 | 410
Rheumatoid Arthritis 21 | 1,171
Stomach Neoplasms 21 | 282
group 4 medulloblastoma 21 | 1,875
pituitary cancer 21 | 1,972
non primary Sjogren syndrome sicca 20 | 840
juvenile dermatomyositis 19 | 1,189
medulloblastoma 19 | 1,524
Osteoporosis 18 | 259
tuberculosis 18 | 1,563
Mammary Neoplasms, Experimental 17 | 150
Amyotrophic Lateral Sclerosis 16 | 432
Animal Mammary Neoplasms 16 | 136
Duchenne muscular dystrophy 16 | 602
Neurodegenerative disease 16 | 383
Parkinson's disease 15 | 364
Prostatic Neoplasms 15 | 471
atypical teratoid/rhabdoid tumor 15 | 1,095
interstitial cystitis 15 | 2,299
Neoplasm Invasiveness 14 | 127
Neoplasm Metastasis 14 | 138
adrenocortical carcinoma 14 | 1,427
posterior fossa group A ependymoma 14 | 1,511
Acute coronary syndrome 13 | 37
HIV Infections 13 | 100
Vascular disease 13 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
ductal carcinoma in situ 13 | 1,745
Atopic dermatitis 12 | 944
Degenerative polyarthritis 12 | 93
Down syndrome 12 | 548
Kidney disease 12 | 397
nasopharyngeal carcinoma 12 | 1,056
sonic hedgehog group medulloblastoma 12 | 1,482
acute myeloid leukemia 11 | 785
non-small cell lung carcinoma 11 | 413
posterior fossa group B ependymoma 11 | 1,530
spina bifida 11 | 1,064
tuberculosis and treatment for 6 months 11 | 686
Adenocarcinoma 10 | 115
Disease Progression 10 | 125
Drug-Induced Liver Injury 10 | 118
Intellectual disability 10 | 573
Myocardial Ischemia 10 | 169
aldosterone-producing adenoma 10 | 664
gastric carcinoma 10 | 832
Esophageal Neoplasms 9 | 67
Neuropathy 9 | 210
Obesity 9 | 616
hepatocellular carcinoma 9 | 550
hereditary spastic paraplegia 9 | 313
Epilepsy 8 | 346
Hypertension 8 | 293
Liver disease 8 | 219
Lung Neoplasms 8 | 171
Squamous cell carcinoma of esophagus 8 | 82
active Crohn's disease 8 | 918
pancreatic carcinoma 8 | 567

Tissue

Cardiovascular System 191 | 17,958
Digestive Tract 191 | 18,473
Endocrine System 191 | 18,512
Female tissues 191 | 18,647
Liver and Pancreas 191 | 18,136
Male tissues 191 | 17,969
Nervous System 191 | 18,561
Urinary Tract 191 | 18,444
Blood and immune system 190 | 17,995
Respiratory system 190 | 17,484
Skin and soft tissues 189 | 18,115

Target Family

Non-IDG 111 | 11,969
Enzyme 74 | 4,146
Kinase 6 | 634
Epigenetic 2 | 242

Jensen-KB Tissue

Interstitial cell of Cajal 193 | 193
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.42607 27.2 143
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
T-complex protein 1 subunit eta CCT7 Tbio Non-IDG -1.42545 25.9 158
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.90129 787.3 198
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.18574 145.2 256
Aldose reductase AKR1B1 Tclin Enzyme -3.25679 1851.0 302
Serine-threonine kinase receptor-associated protein STRAP Tbio Enzyme -1.30190 20.6 123
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.66772 4499.1 1649
Cytoplasmic dynein 1 intermediate chain 2 DYNC1I2 Tbio Non-IDG -2.25048 162.2 87
Phosphatidylinositol transfer protein alpha isoform PITPNA Tbio Non-IDG -1.53691 36.3 117