Development Level

Tbio 82 | 10,625
Tdark 21 | 7,003
Tchem 7 | 1,890
Tclin 6 | 602

Collection

GPCR: IDG Consortium (Targets) 1 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 633
abnormal behavior 2 | 226
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal ovary morphology 1 | 3
abnormal pelvic girdle bone mo... 1 | 11
abnormal seminal vesicle morph... 1 | 47
abnormal spinal cord morpholog... 1 | 8
abnormal testis morphology 1 | 30
absent epididymis 1 | 2
absent ovary 1 | 2
absent seminal vesicle 1 | 2
absent teeth 1 | 4
absent testes 1 | 2
absent uterus 1 | 1
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating free fat... 1 | 39
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged urinary bladder 1 | 4
female infertility 1 | 34
hypoactivity 1 | 89
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
male infertility 1 | 62
polydactyly 1 | 22
prenatal lethality prior to he... 1 | 64
small epididymis 1 | 3
small kidney 1 | 10
small superior vagus ganglion 1 | 20
small testis 1 | 37
sparse hair 1 | 6
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

ovarian cancer 75 | 8,491
osteosarcoma 51 | 7,933
medulloblastoma, large-cell 48 | 6,234
glioblastoma 37 | 5,572
psoriasis 36 | 6,685
atypical teratoid / rhabdoid tumor 33 | 4,369
lung cancer 33 | 4,473
Multiple myeloma 28 | 1,327
astrocytic glioma 25 | 2,241
oligodendroglioma 25 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
primitive neuroectodermal tumor 22 | 3,031
Pick disease 21 | 1,893
pilocytic astrocytoma 21 | 3,086
Breast cancer 20 | 3,098
ependymoma 20 | 2,514
malignant mesothelioma 20 | 3,163
invasive ductal carcinoma 19 | 2,950
lung adenocarcinoma 19 | 2,714
group 3 medulloblastoma 18 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
lung carcinoma 18 | 2,844
pancreatic cancer 17 | 2,300
tuberculosis 17 | 1,563
group 4 medulloblastoma 16 | 1,875
pediatric high grade glioma 16 | 2,712
adult high grade glioma 15 | 2,148
astrocytoma 14 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
medulloblastoma 14 | 1,524
ulcerative colitis 13 | 2,087
acute quadriplegic myopathy 12 | 1,157
non-small cell lung cancer 12 | 2,798
subependymal giant cell astrocytoma 12 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
primary pancreatic ductal adenocarcinoma 11 | 1,271
breast carcinoma 10 | 1,614
cystic fibrosis 10 | 1,670
diabetes mellitus 10 | 1,663
interstitial cystitis 9 | 2,299
juvenile dermatomyositis 9 | 1,189
Amyotrophic Lateral Sclerosis 8 | 432
Neurodegenerative disease 8 | 383
active Crohn's disease 8 | 918
colon cancer 8 | 1,475
pituitary cancer 8 | 1,972
primary Sjogren syndrome 8 | 788
Epilepsy 7 | 346
Waldenstrons macroglobulinemia 7 | 764
acute myeloid leukemia 7 | 785
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
progressive supranuclear palsy 7 | 674
Cancer 6 | 2,346
adrenocortical carcinoma 6 | 1,427
atypical teratoid/rhabdoid tumor 6 | 1,095
non primary Sjogren syndrome sicca 6 | 840
posterior fossa group B ependymoma 6 | 1,530
sonic hedgehog group medulloblastoma 6 | 1,482
Carcinoma 5 | 2,147
Parkinson's disease 5 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
inflammatory breast cancer 5 | 404
mucosa-associated lymphoid tissue lymphoma 5 | 480
posterior fossa group A ependymoma 5 | 1,511
Down syndrome 4 | 548
Duchenne muscular dystrophy 4 | 602
IGA Glomerulonephritis 4 | 454
Myocardial Ischemia 4 | 169
Obesity 4 | 616
Schizophrenia 4 | 503
aldosterone-producing adenoma 4 | 664
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 832
nasopharyngeal carcinoma 4 | 1,056
nephrosclerosis 4 | 329
urothelial carcinoma 4 | 318
Alzheimer's disease 3 | 644
Anemia 3 | 252
Asthma 3 | 349
Bipolar Disorder 3 | 266
Degenerative polyarthritis 3 | 93
Diabetes mellitus type 2 3 | 69
Hypertension 3 | 293
Rheumatoid Arthritis 3 | 1,170
Treatment Refractory Type 2 Diabetes Mellitus 3 | 53
active ulcerative colitis 3 | 477
cutaneous lupus erythematosus 3 | 1,056
hepatocellular carcinoma 3 | 550
hereditary spastic paraplegia 3 | 313
pancreatic carcinoma 3 | 567
sarcoidosis 3 | 368
substance-related disorder 3 | 104
tuberculosis and treatment for 6 months 3 | 686
Coronary artery disease 2 | 240
Heart disease 2 | 279
Multiple Sclerosis 2 | 498
Stomach Neoplasms 2 | 282
fibroadenoma 2 | 557
spina bifida 2 | 1,064

Tissue

Nervous System 116 | 18,560
Cardiovascular System 114 | 17,957
Digestive Tract 114 | 18,472
Endocrine System 114 | 18,511
Female tissues 114 | 18,646
Liver and Pancreas 114 | 18,135
Skin and soft tissues 114 | 18,114
Urinary Tract 114 | 18,443
Male tissues 113 | 17,968
Blood and immune system 112 | 17,994
Respiratory system 110 | 17,483

Target Family

Non-IDG 71 | 11,969
Enzyme 29 | 4,146
Kinase 5 | 634
Transporter 4 | 473
GPCR 3 | 408
Ion Channel 2 | 341
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Hypothalamus 116 | 116
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ethylmalonyl-CoA decarboxylase ECHDC1 Tbio Enzyme -2.14463 126.6 79
Regulating synaptic membrane exocytosis protein 2 RIMS2 Tbio Non-IDG -1.59472 39.9 142
Ceramide synthase 1 CERS1 Tbio Enzyme -1.57090 34.6 153
Apelin APLN Tchem Non-IDG -2.67083 561.4 181
Rap guanine nucleotide exchange factor 4 RAPGEF4 Tchem Non-IDG -2.44186 267.7 112
Actin-related protein 10 ACTR10 Tdark Non-IDG -0.71251 4.03 46
Mitoferrin-1 SLC25A37 Tbio Transporter -1.54718 33.3 88
INO80 complex subunit C INO80C Tdark Non-IDG 0.00000 16
PDZ and LIM domain protein 2 PDLIM2 Tbio Non-IDG -2.41620 261.2 97
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.21018 16.2 189