Development Level

Tbio 85 | 11,651
Tdark 19 | 6,593
Tchem 7 | 1,388
Tclin 6 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal kidney morphology 3 | 65
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased heart weight 2 | 27
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hair growth 1 | 10
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal ovary morphology 1 | 7
abnormal pelvic girdle bone mo... 1 | 12
abnormal spinal cord morpholog... 1 | 9
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
absent epididymis 1 | 3
absent ovary 1 | 3
absent seminal vesicle 1 | 4
absent teeth 1 | 3
absent testes 1 | 6
absent uterus 1 | 1
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged urinary bladder 1 | 8
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small epididymis 1 | 3
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
thick skin 1 | 4
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

ovarian cancer 75 | 8,520
Carcinoma 56 | 11,493
osteosarcoma 52 | 7,950
medulloblastoma, large-cell 48 | 6,241
atypical teratoid / rhabdoid tumor 38 | 5,112
glioblastoma 37 | 5,792
psoriasis 36 | 6,694
group 3 medulloblastoma 33 | 4,104
lung cancer 32 | 4,740
astrocytic glioma 31 | 2,597
ependymoma 31 | 4,679
Multiple myeloma 28 | 1,332
adult high grade glioma 26 | 3,801
oligodendroglioma 25 | 2,850
Breast cancer 24 | 3,578
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
primitive neuroectodermal tumor 22 | 3,035
Pick disease 21 | 1,894
malignant mesothelioma 20 | 3,232
Astrocytoma, Pilocytic 19 | 3,081
invasive ductal carcinoma 19 | 2,951
lung adenocarcinoma 19 | 2,716
tuberculosis 19 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung carcinoma 18 | 2,843
pancreatic cancer 17 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
group 4 medulloblastoma 13 | 1,855
non-small cell lung cancer 13 | 2,890
acute quadriplegic myopathy 12 | 1,158
subependymal giant cell astrocytoma 12 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
breast carcinoma 10 | 1,638
cystic fibrosis 10 | 1,696
diabetes mellitus 10 | 1,728
primary pancreatic ductal adenocarcinoma 10 | 1,109
interstitial cystitis 9 | 2,312
juvenile dermatomyositis 9 | 1,187
ulcerative colitis 9 | 1,819
Amyotrophic lateral sclerosis 8 | 451
Epilepsy 8 | 792
Neurodegenerative disease 8 | 414
Schizophrenia 8 | 1,160
active Crohn's disease 8 | 922
acute myeloid leukemia 8 | 783
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
pituitary cancer 8 | 1,972
primary Sjogren syndrome 8 | 735
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
progressive supranuclear palsy 7 | 676
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Cancer 6 | 2,499
Kidney cancer 6 | 2,613
adrenocortical carcinoma 6 | 1,428
non primary Sjogren syndrome sicca 6 | 891
Depressive disorder 5 | 409
Parkinson's disease 5 | 392
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
medulloblastoma 5 | 720
mucosa-associated lymphoid tissue lymphoma 5 | 484
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
Dementia 4 | 175
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Liver Cirrhosis, Experimental 4 | 769
Myocardial Ischemia 4 | 169
Obesity 4 | 678
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
nephrosclerosis 4 | 333
substance-related disorder 4 | 162
urothelial carcinoma 4 | 318
Alzheimer's disease 3 | 658
Anemia 3 | 365
Asthma 3 | 385
Cerebellar Ataxia 3 | 304
Degenerative polyarthritis 3 | 115
Diabetes mellitus type 2 3 | 69
Dysarthria 3 | 192
Glycogen storage disease 3 | 39
Hyperreflexia 3 | 209
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Melanoma 3 | 711
Neuropathy 3 | 261
Osteoarthritis 3 | 184
Rheumatoid arthritis 3 | 1,191
cutaneous lupus erythematosus 3 | 1,057
hepatocellular carcinoma 3 | 547
hereditary spastic paraplegia 3 | 318
pancreatic carcinoma 3 | 562
sarcoidosis 3 | 370
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 114 | 17,369
Endocrine System 114 | 18,159
Female tissues 113 | 17,400
Liver and Pancreas 113 | 16,750
Nervous System 113 | 16,725
Skin and soft tissues 113 | 17,230
Blood and immune system 112 | 16,909
Respiratory system 110 | 16,393
Cardiovascular System 109 | 15,192
Male tissues 109 | 17,142
Urinary Tract 109 | 16,678

Target Family

Non-IDG 72 | 12,091
Enzyme 29 | 4,145
Kinase 5 | 634
Transporter 4 | 473
GPCR 3 | 408
Ion Channel 2 | 344
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Hypothalamus 117 | 117
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.22337 16.5 217
BRCA1-A complex subunit RAP80 UIMC1 Tbio Non-IDG -1.69622 52.7 176
Protein FAM131B FAM131B Tdark Non-IDG 0.11 0.98 27
Chromatin target of PRMT1 protein CHTOP Tbio Non-IDG -1.08937 13.2 96
Protein prune homolog 2 PRUNE2 Tbio Non-IDG -1.04301 12.3 82
Apelin APLN Tchem Non-IDG -2.71691 609.6 214
Secernin-1 SCRN1 Tbio Enzyme -0.95833 9.26 110
N-acetylneuraminate lyase NPL Tbio Enzyme -3.10700 1259.2 86
Neuronal vesicle trafficking-associated protein 2 NSG2 Tdark Non-IDG -1.57749 32.5 47
Sulfotransferase 4A1 SULT4A1 Tbio Enzyme -1.85825 71.3 129