1. Home
  2. Targets
Target Filters...

Development Level

Tbio 95 | 11,651
Tdark 15 | 6,593
Tclin 10 | 612
Tchem 8 | 1,388

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 5 | 298
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
impaired glucose tolerance 4 | 75
increased total body fat amoun... 4 | 134
decreased circulating choleste... 3 | 93
embryonic lethality prior to t... 3 | 278
increased lean body mass 3 | 172
increased startle reflex 3 | 112
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
thrombocytosis 2 | 27
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal optic disc morphology 1 | 10
abnormal pancreas morphology 1 | 13
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating creatine... 1 | 4
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
long tibia 1 | 25
microphthalmia 1 | 26
small heart 1 | 10
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

ovarian cancer 79 | 8,520
Carcinoma 70 | 11,493
osteosarcoma 52 | 7,950
medulloblastoma, large-cell 46 | 6,241
psoriasis 45 | 6,694
lung cancer 43 | 4,740
ependymoma 39 | 4,679
glioblastoma 37 | 5,792
atypical teratoid / rhabdoid tumor 35 | 5,112
Breast cancer 33 | 3,578
Multiple myeloma 31 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
oligodendroglioma 25 | 2,850
adult high grade glioma 22 | 3,801
pituitary cancer 22 | 1,972
Cancer 21 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
astrocytic glioma 20 | 2,597
group 3 medulloblastoma 20 | 4,104
lung adenocarcinoma 20 | 2,716
pancreatic cancer 19 | 2,398
primitive neuroectodermal tumor 19 | 3,035
lung carcinoma 18 | 2,843
malignant mesothelioma 18 | 3,232
Pick disease 17 | 1,894
colon cancer 17 | 1,478
non-small cell lung cancer 17 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Astrocytoma, Pilocytic 16 | 3,081
Autosomal recessive predisposition 16 | 1,442
subependymal giant cell astrocytoma 16 | 2,287
diabetes mellitus 15 | 1,728
Waldenstrons macroglobulinemia 14 | 765
breast carcinoma 14 | 1,638
invasive ductal carcinoma 14 | 2,951
Osteoporosis 13 | 363
ductal carcinoma in situ 13 | 1,745
Kidney cancer 12 | 2,613
adrenocortical carcinoma 12 | 1,428
primary pancreatic ductal adenocarcinoma 12 | 1,109
ulcerative colitis 12 | 1,819
Schizophrenia 11 | 1,160
cystic fibrosis 11 | 1,696
Bipolar Disorder 10 | 666
Epilepsy 10 | 792
Neurodegenerative disease 10 | 414
Obesity 10 | 678
astrocytoma 10 | 1,146
juvenile dermatomyositis 10 | 1,187
Alzheimer's disease 9 | 658
group 4 medulloblastoma 9 | 1,855
medulloblastoma 9 | 720
spina bifida 9 | 1,074
tuberculosis 9 | 2,010
Depressive disorder 8 | 409
Hypertension 8 | 396
Liver Cirrhosis, Experimental 8 | 769
Prostatic Neoplasms 8 | 495
dermatomyositis 8 | 966
interstitial cystitis 8 | 2,312
Atopic dermatitis 7 | 952
Cognitive delay 7 | 608
Duchenne muscular dystrophy 7 | 601
Global developmental delay 7 | 608
Hypoglycemia 7 | 152
Hypothyroidism 7 | 122
Intellectual disability 7 | 1,016
Major Depressive Disorder 7 | 301
Mental and motor retardation 7 | 608
acute quadriplegic myopathy 7 | 1,158
pediatric high grade glioma 7 | 1,064
Adenoma 6 | 167
Alcoholic Intoxication, Chronic 6 | 289
Dull intelligence 6 | 645
Hypertensive disease 6 | 292
Hypopituitarism 6 | 40
Low intelligence 6 | 645
Melanoma 6 | 711
Mental Depression 6 | 333
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle Spasticity 6 | 195
Muscle hypotonia 6 | 571
Polycystic ovary syndrome 6 | 360
Poor school performance 6 | 645
aldosterone-producing adenoma 6 | 665
gastric carcinoma 6 | 807
pancreatic carcinoma 6 | 562
Amyotrophic lateral sclerosis 5 | 451
Delayed bone age 5 | 136
Endometriosis 5 | 540
Malaria 5 | 160
Mood Disorders 5 | 184
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
adrenocortical adenoma 5 | 131
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510

Tissue

Endocrine System 123 | 18,159
Digestive Tract 120 | 17,369
Skin and soft tissues 119 | 17,230
Female tissues 118 | 17,400
Nervous System 118 | 16,725
Blood and immune system 117 | 16,909
Respiratory system 117 | 16,393
Male tissues 116 | 17,142
Urinary Tract 115 | 16,678
Liver and Pancreas 114 | 16,750
Cardiovascular System 108 | 15,192

Target Family

Non-IDG 75 | 12,091
Enzyme 26 | 4,145
GPCR 9 | 408
Transcription Factor 6 | 1,400
Kinase 4 | 634
Epigenetic 3 | 242
Ion Channel 3 | 344
Nuclear Receptor 1 | 48
Transporter 1 | 473

Jensen-KB Tissue

Hypophysis 128 | 128
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin superfamily member 1 IGSF1 Tbio Non-IDG -1.62840 43.8 149
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 CHCHD2 Tbio Non-IDG -1.33813 39.8 99
BRISC and BRCA1-A complex member 1 BABAM1 Tbio Non-IDG -1.20557 16.7 162
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Spindlin-1 SPIN1 Tbio Non-IDG -2.02987 109.3 128
Secretogranin-3 SCG3 Tbio Non-IDG -1.59072 42.1 169
Cilia- and flagella-associated protein 20 CFAP20 Tbio Non-IDG -1.78803 43.9 88
Ancient ubiquitous protein 1 AUP1 Tbio Non-IDG -1.00442 12.6 142
Coatomer subunit gamma-1 COPG1 Tbio Non-IDG -1.70829 49.0 89