Development Level

Tbio 331 | 11,445
Tdark 91 | 6,588
Tchem 76 | 1,598
Tclin 33 | 613

Collection

Ion Channel: IDG Consortium (T... 10 | 99
Kinase: IDG Consortium (Target... 5 | 125
GPCR: IDG Consortium (Targets) 4 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 32 | 979
preweaning lethality, incomple... 24 | 499
abnormal behavior 14 | 298
decreased total body fat amoun... 14 | 207
hyperactivity 14 | 148
abnormal bone structure 10 | 187
decreased vertical activity 10 | 208
abnormal embryo size 9 | 220
increased startle reflex 9 | 112
decreased body weight 8 | 161
embryonic lethality prior to t... 8 | 278
decreased prepulse inhibition 7 | 82
enlarged heart 7 | 210
hypoactivity 7 | 132
decreased lymphocyte cell numb... 6 | 83
embryonic lethality prior to o... 6 | 239
impaired pupillary reflex 6 | 26
improved glucose tolerance 6 | 79
increased circulating alkaline... 6 | 122
increased mean corpuscular vol... 6 | 92
abnormal heart morphology 5 | 162
abnormal seminal vesicle morph... 5 | 114
decreased body length 5 | 101
increased bone mineral content 5 | 108
increased bone mineral density 5 | 72
increased lean body mass 5 | 172
increased mean corpuscular hem... 5 | 96
increased total body fat amoun... 5 | 134
limb grasping 5 | 41
male infertility 5 | 123
abnormal lens morphology 4 | 81
cataract 4 | 92
decreased bone mineral content 4 | 151
decreased circulating triglyce... 4 | 79
decreased leukocyte cell numbe... 4 | 73
edema 4 | 59
increased blood urea nitrogen ... 4 | 48
increased body length 4 | 32
increased circulating choleste... 4 | 66
increased circulating iron lev... 4 | 30
small testis 4 | 58
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
abnormal tail movements 3 | 12
abnormal testis morphology 3 | 43
anophthalmia 3 | 33
cardiovascular system phenotyp... 3 | 36
decreased circulating amylase ... 3 | 28
decreased circulating aspartat... 3 | 34
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased mean corpuscular hem... 3 | 50
decreased threshold for audito... 3 | 26
female infertility 3 | 60
increased circulating HDL chol... 3 | 80
increased hemoglobin content 3 | 45
increased prepulse inhibition 3 | 32
abnormal cornea morphology 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal locomotor activation 2 | 16
abnormal neural tube closure 2 | 46
abnormal retinal vasculature m... 2 | 27
abnormal startle reflex 2 | 15
abnormal tooth morphology 2 | 24
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating fructosa... 2 | 30
decreased circulating sodium l... 2 | 22
decreased grip strength 2 | 116
decreased heart rate variabili... 2 | 13
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased startle reflex 2 | 75
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating alanine ... 2 | 13
increased circulating aspartat... 2 | 15
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased circulating free fat... 2 | 20
increased circulating glucose ... 2 | 24
increased circulating triglyce... 2 | 42
increased eosinophil cell numb... 2 | 11
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
small superior vagus ganglion 2 | 74
tremors 2 | 39
trunk curl 2 | 16

Disease

Carcinoma 395 | 11,493
ovarian cancer 277 | 8,520
medulloblastoma, large-cell 273 | 6,241
glioblastoma 259 | 5,792
atypical teratoid / rhabdoid tumor 256 | 5,112
osteosarcoma 256 | 7,950
ependymoma 223 | 4,679
psoriasis 204 | 6,694
adult high grade glioma 176 | 3,801
lung cancer 170 | 4,740
group 3 medulloblastoma 168 | 4,104
primitive neuroectodermal tumor 167 | 3,035
oligodendroglioma 166 | 2,850
astrocytic glioma 153 | 2,597
Astrocytoma, Pilocytic 149 | 3,081
Pick disease 126 | 1,894
Breast cancer 117 | 3,578
malignant mesothelioma 115 | 3,232
lung carcinoma 114 | 2,843
Kidney cancer 111 | 2,613
lung adenocarcinoma 111 | 2,716
subependymal giant cell astrocytoma 110 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 108 | 3,291
invasive ductal carcinoma 107 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 106 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 100 | 2,989
non-small cell lung cancer 96 | 2,890
group 4 medulloblastoma 94 | 1,855
pituitary cancer 89 | 1,972
interstitial cystitis 79 | 2,312
pancreatic cancer 79 | 2,398
Cancer 75 | 2,499
Schizophrenia 74 | 1,160
ductal carcinoma in situ 70 | 1,745
tuberculosis 69 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 68 | 1,962
ulcerative colitis 62 | 1,819
breast carcinoma 56 | 1,638
cystic fibrosis 56 | 1,696
Epilepsy 54 | 792
colon cancer 54 | 1,478
acute quadriplegic myopathy 49 | 1,158
juvenile dermatomyositis 49 | 1,187
Autosomal recessive predisposition 47 | 1,442
Bipolar Disorder 46 | 666
Multiple myeloma 46 | 1,332
Intellectual disability 45 | 1,016
adrenocortical carcinoma 45 | 1,428
Rheumatoid arthritis 43 | 1,191
astrocytoma 42 | 1,146
Down syndrome 41 | 499
pediatric high grade glioma 41 | 1,064
dermatomyositis 38 | 966
Seizures 37 | 596
Atopic dermatitis 35 | 952
medulloblastoma 35 | 720
primary pancreatic ductal adenocarcinoma 34 | 1,109
progressive supranuclear palsy 34 | 676
Muscle hypotonia 33 | 571
diabetes mellitus 33 | 1,728
Alzheimer's disease 32 | 658
active Crohn's disease 32 | 922
Dull intelligence 30 | 645
Low intelligence 30 | 645
Mental Retardation 30 | 645
Mental deficiency 30 | 645
Poor school performance 30 | 645
Depressive disorder 29 | 409
Waldenstrons macroglobulinemia 29 | 765
non primary Sjogren syndrome sicca 29 | 891
Obesity 28 | 678
Cognitive delay 27 | 608
Duchenne muscular dystrophy 27 | 601
Global developmental delay 27 | 608
Mental and motor retardation 27 | 608
aldosterone-producing adenoma 27 | 665
cutaneous lupus erythematosus 27 | 1,057
gastric carcinoma 27 | 807
nasopharyngeal carcinoma 27 | 1,058
spina bifida 27 | 1,074
Liver Cirrhosis, Experimental 26 | 769
Mental Depression 26 | 333
active ulcerative colitis 26 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 510
Alcoholic Intoxication, Chronic 25 | 289
Parkinson's disease 25 | 392
Prostatic Neoplasms 25 | 495
primary Sjogren syndrome 25 | 735
Liver cancer 24 | 604
esophageal adenocarcinoma 23 | 737
gastric cancer 23 | 459
Attention deficit hyperactivity disorder 22 | 278
Small head 22 | 374
acute myeloid leukemia 22 | 783
pancreatic carcinoma 22 | 562
Autistic Disorder 21 | 364
Major Depressive Disorder 21 | 301
Melanoma 21 | 711
Neurodegenerative disease 20 | 414
Asthma 19 | 385

Tissue

Endocrine System 521 | 18,159
Nervous System 521 | 16,725
Female tissues 518 | 17,400
Digestive Tract 516 | 17,369
Skin and soft tissues 510 | 17,230
Male tissues 507 | 17,142
Blood and immune system 502 | 16,909
Liver and Pancreas 501 | 16,750
Urinary Tract 499 | 16,678
Respiratory system 487 | 16,393
Cardiovascular System 477 | 15,192

Target Family

Non-IDG 267 | 12,091
Enzyme 129 | 4,145
Transcription Factor 32 | 1,400
Ion Channel 28 | 344
Kinase 28 | 634
GPCR 17 | 408
Transporter 16 | 473
Epigenetic 10 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Hippocampus 531 | 531
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Nicotinamide riboside kinase 1 NMRK1 Tbio Kinase -0.84939 6.66 143
Zinc finger protein 346 ZNF346 Tbio Non-IDG -2.28393 188.7 213
Delta-1-pyrroline-5-carboxylate synthase ALDH18A1 Tbio Enzyme -2.34260 216.5 146
Probable palmitoyltransferase ZDHHC8 ZDHHC8 Tbio Enzyme -1.30633 19.3 116
Gypsy retrotransposon integrase-like protein 1 GIN1 Tdark Enzyme -1.99075 95.6 47
Sodium-dependent proline transporter SLC6A7 Tchem Transporter -2.10260 134.1 45
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Transmembrane prolyl 4-hydroxylase P4HTM Tchem Enzyme -2.70235 473.8 159
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206