Development Level

Tbio 165 | 11,651
Tdark 47 | 6,593
Tchem 26 | 1,388
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 20 | 979
embryonic lethality prior to o... 11 | 239
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to t... 5 | 278
prenatal lethality prior to he... 5 | 87
abnormal behavior 4 | 298
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating total pr... 4 | 49
decreased vertical activity 4 | 208
enlarged heart 4 | 210
increased lean body mass 4 | 172
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased prepulse inhibition 3 | 82
hyperactivity 3 | 148
abnormal coat- hair morphology 2 | 19
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal locomotor activation 2 | 16
abnormal snout morphology 2 | 23
abnormal vibrissa morphology 2 | 25
corneal opacity 2 | 32
decreased bone mineral density 2 | 126
decreased circulating aspartat... 2 | 34
decreased circulating creatini... 2 | 39
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
increased body weight 2 | 25
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
tremors 2 | 39
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal defecation 1 | 1
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pharyngeal arch morph... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
absent teeth 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart rate 1 | 23
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
shortened PQ interval 1 | 7
small testis 1 | 58
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 185 | 11,493
ovarian cancer 150 | 8,520
osteosarcoma 118 | 7,950
medulloblastoma, large-cell 97 | 6,241
psoriasis 95 | 6,694
lung cancer 82 | 4,740
glioblastoma 81 | 5,792
atypical teratoid / rhabdoid tumor 65 | 5,112
group 3 medulloblastoma 61 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,291
ependymoma 55 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,989
Breast cancer 50 | 3,578
non-small cell lung cancer 50 | 2,890
malignant mesothelioma 49 | 3,232
Kidney cancer 46 | 2,613
Cancer 45 | 2,499
adult high grade glioma 44 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 44 | 1,962
invasive ductal carcinoma 42 | 2,951
Multiple myeloma 41 | 1,332
oligodendroglioma 41 | 2,850
pancreatic cancer 41 | 2,398
primitive neuroectodermal tumor 40 | 3,035
diabetes mellitus 35 | 1,728
interstitial cystitis 34 | 2,312
subependymal giant cell astrocytoma 33 | 2,287
astrocytic glioma 32 | 2,597
lung adenocarcinoma 32 | 2,716
Astrocytoma, Pilocytic 30 | 3,081
lung carcinoma 28 | 2,843
colon cancer 26 | 1,478
tuberculosis 26 | 2,010
adrenocortical carcinoma 25 | 1,428
pituitary cancer 25 | 1,972
Pick disease 24 | 1,894
group 4 medulloblastoma 24 | 1,855
astrocytoma 22 | 1,146
dermatomyositis 22 | 966
ductal carcinoma in situ 22 | 1,745
breast carcinoma 21 | 1,638
Waldenstrons macroglobulinemia 20 | 765
cystic fibrosis 20 | 1,696
acute quadriplegic myopathy 19 | 1,158
juvenile dermatomyositis 19 | 1,187
ulcerative colitis 19 | 1,819
primary pancreatic ductal adenocarcinoma 18 | 1,109
Atopic dermatitis 17 | 952
Autosomal recessive predisposition 17 | 1,442
spina bifida 15 | 1,074
Schizophrenia 14 | 1,160
acute myeloid leukemia 14 | 783
esophageal adenocarcinoma 14 | 737
nasopharyngeal carcinoma 14 | 1,058
non primary Sjogren syndrome sicca 14 | 891
Intellectual disability 13 | 1,016
Liver cancer 13 | 604
Muscle hypotonia 13 | 571
Obesity 13 | 678
Rheumatoid arthritis 13 | 1,191
cutaneous lupus erythematosus 13 | 1,057
pediatric high grade glioma 13 | 1,064
Alzheimer's disease 12 | 658
Amyotrophic lateral sclerosis 11 | 451
Endometrial cancer 11 | 311
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
tuberculosis and treatment for 6 months 11 | 409
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Prostatic Neoplasms 10 | 495
chronic rhinosinusitis 10 | 512
hepatocellular carcinoma 10 | 547
Epilepsy 9 | 792
Parkinson's disease 9 | 392
active Crohn's disease 9 | 922
aldosterone-producing adenoma 9 | 665
medulloblastoma 9 | 720
pancreatic carcinoma 9 | 562
Dull intelligence 8 | 645
Failure to gain weight 8 | 365
Hepatomegaly 8 | 285
Liver Cirrhosis, Experimental 8 | 769
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Pediatric failure to thrive 8 | 365
Poor school performance 8 | 645
Seizures 8 | 596
gastric carcinoma 8 | 807
hereditary spastic paraplegia 8 | 318
mucosa-associated lymphoid tissue lymphoma 8 | 484
progressive supranuclear palsy 8 | 676
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Short stature 7 | 531
Small head 7 | 374
Vascular disease 7 | 319
posterior fossa group A ependymoma 7 | 468

Tissue

Endocrine System 242 | 18,159
Female tissues 240 | 17,400
Blood and immune system 238 | 16,909
Skin and soft tissues 238 | 17,230
Digestive Tract 237 | 17,369
Liver and Pancreas 237 | 16,750
Male tissues 237 | 17,142
Urinary Tract 235 | 16,678
Nervous System 234 | 16,725
Respiratory system 234 | 16,393
Cardiovascular System 231 | 15,192

Target Family

Non-IDG 137 | 12,091
Enzyme 56 | 4,145
Transcription Factor 20 | 1,400
Kinase 10 | 634
Transporter 9 | 473
Epigenetic 8 | 242
Nuclear Receptor 2 | 48
GPCR 1 | 408
Ion Channel 1 | 344

Jensen-KB Tissue

Hepatoma cell 244 | 244
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Proprotein convertase subtilisin/kexin type 6 PCSK6 Tchem Enzyme -2.33983 216.4 239
Mitogen-activated protein kinase 7 MAPK7 Tbio Kinase -2.48754 340.0 422
Zinc finger protein 407 ZNF407 Tdark Transcription Factor -0.68124 3.81 38
WD repeat-containing protein 82 WDR82 Tbio Non-IDG -1.00294 10.5 68
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
Palmitoyltransferase ZDHHC7 ZDHHC7 Tbio Enzyme -1.01816 7.69 109
Apolipoprotein F APOF Tbio Non-IDG -1.45156 33.3 232