Development Level

Tbio 149 | 10,625
Tdark 55 | 7,003
Tchem 32 | 1,890
Tclin 6 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 8 | 148
decreased circulating choleste... 5 | 85
decreased lean body mass 5 | 195
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
abnormal retina morphology 4 | 100
decreased circulating HDL chol... 4 | 77
decreased circulating triglyce... 4 | 83
abnormal embryo size 3 | 112
decreased body weight 3 | 174
decreased circulating glucose ... 3 | 121
decreased prepulse inhibition 3 | 52
embryonic lethality prior to t... 3 | 187
enlarged heart 3 | 111
increased body weight 3 | 42
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
prenatal lethality prior to he... 3 | 64
abnormal head morphology 2 | 10
abnormal locomotor activation 2 | 26
abnormal retinal pigmentation 2 | 61
corneal opacity 2 | 25
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
hyperactivity 2 | 108
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating serum al... 2 | 25
increased or absent threshold ... 2 | 128
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal defecation 1 | 1
abnormal embryo turning 1 | 15
abnormal eyelid morphology 1 | 6
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal respiratory quotient 1 | 9
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
abnormal vocalization 1 | 21
absent teeth 1 | 4
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, CD25-p... 1 | 24
decreased basophil cell number 1 | 11
decreased bone mineral content 1 | 157
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
hydrometra 1 | 13
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased lymphocyte cell numb... 1 | 9
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
long tibia 1 | 13
microphthalmia 1 | 15
persistence of hyaloid vascula... 1 | 22
shortened PQ interval 1 | 6
shortened ST segment 1 | 9
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
small testis 1 | 37
small thymus 1 | 11
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 148 | 8,484
osteosarcoma 116 | 7,933
medulloblastoma, large-cell 95 | 6,234
psoriasis 95 | 6,685
lung cancer 80 | 4,466
glioblastoma 79 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,956
atypical teratoid / rhabdoid tumor 56 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,289
non-small cell lung cancer 49 | 2,798
Breast cancer 47 | 3,094
malignant mesothelioma 46 | 3,162
Cancer 41 | 2,346
invasive ductal carcinoma 41 | 2,950
oligodendroglioma 40 | 2,849
Multiple myeloma 39 | 1,327
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,795
primitive neuroectodermal tumor 39 | 3,031
pancreatic cancer 37 | 2,300
Carcinoma 35 | 2,147
pediatric high grade glioma 35 | 2,712
diabetes mellitus 34 | 1,663
ependymoma 34 | 2,514
interstitial cystitis 34 | 2,299
group 3 medulloblastoma 33 | 2,254
subependymal giant cell astrocytoma 33 | 2,287
lung adenocarcinoma 32 | 2,713
pilocytic astrocytoma 32 | 3,086
astrocytic glioma 29 | 2,241
group 4 medulloblastoma 29 | 1,875
lung carcinoma 28 | 2,844
colon cancer 26 | 1,475
adrenocortical carcinoma 25 | 1,427
pituitary cancer 25 | 1,972
Pick disease 24 | 1,893
astrocytoma 23 | 1,493
dermatomyositis 22 | 933
ductal carcinoma in situ 22 | 1,745
ulcerative colitis 22 | 2,087
adult high grade glioma 21 | 2,148
breast carcinoma 21 | 1,614
primary pancreatic ductal adenocarcinoma 21 | 1,271
Waldenstrons macroglobulinemia 20 | 765
acute quadriplegic myopathy 19 | 1,157
juvenile dermatomyositis 19 | 1,189
medulloblastoma 19 | 1,524
tuberculosis 19 | 1,557
cystic fibrosis 18 | 1,665
Atopic dermatitis 17 | 944
posterior fossa group A ependymoma 17 | 1,511
sonic hedgehog group medulloblastoma 17 | 1,482
tuberculosis and treatment for 6 months 17 | 686
spina bifida 15 | 1,064
esophageal adenocarcinoma 14 | 737
nasopharyngeal carcinoma 14 | 1,056
non primary Sjogren syndrome sicca 14 | 840
Alzheimer's disease 13 | 644
Rheumatoid Arthritis 13 | 1,160
acute myeloid leukemia 13 | 780
cutaneous lupus erythematosus 13 | 1,056
Obesity 11 | 616
Amyotrophic Lateral Sclerosis 10 | 431
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
chronic rhinosinusitis 10 | 512
posterior fossa group B ependymoma 10 | 1,530
active Crohn's disease 9 | 918
aldosterone-producing adenoma 9 | 664
hepatocellular carcinoma 9 | 532
pancreatic carcinoma 9 | 567
IGA Glomerulonephritis 8 | 454
Intellectual disability 8 | 573
Parkinson's disease 8 | 364
Prostatic Neoplasms 8 | 471
atypical teratoid/rhabdoid tumor 8 | 1,095
gastric carcinoma 8 | 832
hereditary spastic paraplegia 8 | 313
mucosa-associated lymphoid tissue lymphoma 8 | 480
progressive supranuclear palsy 8 | 674
Down syndrome 7 | 548
Duchenne muscular dystrophy 7 | 602
Vascular disease 6 | 281
gastric cancer 6 | 430
non-small cell lung carcinoma 6 | 413
primary Sjogren syndrome 6 | 789
tuberculosis and treatment for 3 months 6 | 327
Autistic Disorder 5 | 320
Colorectal Neoplasms 5 | 217
Endometriosis 5 | 535
Gaucher disease type 1 5 | 171
Lung Neoplasms 5 | 171
Myocardial Ischemia 5 | 169
Renal Cell Carcinoma 5 | 199
fibroadenoma 5 | 557
head and neck cancer 5 | 270
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
interstitial lung disease 5 | 291
Crohn's disease 4 | 304
Schizophrenia 4 | 501
inflammatory breast cancer 4 | 404

Tissue

Blood and immune system 240 | 17,995
Endocrine System 240 | 18,512
Female tissues 240 | 18,647
Nervous System 240 | 18,561
Digestive Tract 239 | 18,473
Urinary Tract 239 | 18,444
Liver and Pancreas 238 | 18,136
Male tissues 238 | 17,969
Cardiovascular System 237 | 17,958
Respiratory system 237 | 17,484
Skin and soft tissues 236 | 18,115

Target Family

Non-IDG 136 | 11,971
Enzyme 56 | 4,146
Transcription Factor 20 | 1,400
Kinase 10 | 634
Transporter 9 | 473
Epigenetic 7 | 242
Nuclear Receptor 2 | 48
GPCR 1 | 406
Ion Channel 1 | 341

Jensen-KB Tissue

Hepatoma cell 242 | 242
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
HEAT repeat-containing protein 6 HEATR6 Tdark Non-IDG -1.48236 11.6 38
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Host cell factor 1 HCFC1 Tbio Non-IDG -2.50024 341.6 160
Zinc finger and BTB domain-containing protein 14 ZBTB14 Tbio Transcription Factor -1.28934 22.1 38
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.41582 254.1 201
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
PHD finger protein 20 PHF20 Tbio Epigenetic -2.79926 660.7 91
U3 small nucleolar RNA-associated protein 6 homolog UTP6 Tbio Non-IDG -1.00948 10.4 87