Development Level

Tbio 371 | 10,625
Tdark 90 | 7,003
Tchem 81 | 1,890
Tclin 40 | 602

Collection

Ion Channel: IDG Consortium (Targets) 9 | 102
GPCR: IDG Consortium (Targets) 2 | 127
Kinase: IDG Consortium (Complete/Control) 2 | 37
Kinase: IDG Consortium (Targets) 2 | 125
GPCR: IDG Consortium (Complete/Control) 1 | 26

IMPC Phenotype

preweaning lethality, complete... 24 | 633
embryonic lethality prior to o... 9 | 148
embryonic lethality prior to t... 8 | 187
abnormal embryo size 7 | 112
decreased total body fat amoun... 7 | 186
preweaning lethality, incomple... 7 | 260
decreased body weight 6 | 174
decreased circulating choleste... 6 | 85
increased lean body mass 6 | 107
abnormal behavior 5 | 226
abnormal lens morphology 5 | 73
abnormal retina morphology 5 | 100
decreased grip strength 5 | 123
enlarged heart 5 | 111
hyperactivity 5 | 108
impaired glucose tolerance 5 | 52
increased circulating alkaline... 5 | 119
short tibia 5 | 82
abnormal bone structure 4 | 131
abnormal coat-hair pigmentatio... 4 | 54
abnormal neural tube closure 4 | 37
abnormal retinal pigmentation 4 | 61
cardiovascular system phenotyp... 4 | 35
decreased caudal vertebrae num... 4 | 49
decreased circulating HDL chol... 4 | 77
decreased circulating insulin ... 4 | 75
decreased heart rate variabili... 4 | 11
decreased lean body mass 4 | 195
increased erythrocyte cell num... 4 | 26
increased or absent threshold ... 4 | 128
limb grasping 4 | 35
abnormal bone mineralization 3 | 55
abnormal eye morphology 3 | 38
abnormal gait 3 | 51
abnormal heart morphology 3 | 51
abnormal sleep behavior 3 | 63
decreased circulating alkaline... 3 | 41
decreased circulating glucose ... 3 | 121
decreased eosinophil cell numb... 3 | 41
decreased fasted circulating g... 3 | 49
decreased vertical activity 3 | 22
enlarged spleen 3 | 26
improved glucose tolerance 3 | 56
increased circulating sodium l... 3 | 71
increased hematocrit 3 | 36
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
increased prepulse inhibition 3 | 21
increased startle reflex 3 | 38
male infertility 3 | 62
abnormal behavioral response t... 2 | 52
abnormal cornea morphology 2 | 24
abnormal heart left ventricle ... 2 | 20
abnormal iris morphology 2 | 12
abnormal limb bud morphology 2 | 15
abnormal locomotor activation 2 | 26
abnormal midbrain development 2 | 22
abnormal seminal vesicle morph... 2 | 47
abnormal skin morphology 2 | 23
abnormal tail bud morphology 2 | 6
absent pinna reflex 2 | 21
cataract 2 | 26
corneal opacity 2 | 25
decreased Ly6C low monocyte nu... 2 | 23
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 53
decreased circulating iron lev... 2 | 25
decreased circulating serum al... 2 | 79
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased neutrophil cell numb... 2 | 37
decreased prepulse inhibition 2 | 52
decreased pulmonary respirator... 2 | 4
embryonic growth retardation 2 | 28
enlarged stomach 2 | 2
hydrops fetalis 2 | 22
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
increased circulating magnesiu... 2 | 10
increased heart rate 2 | 17
increased heart weight 2 | 37
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 25
increased sacral vertebrae num... 2 | 62
increased total body fat amoun... 2 | 57
lethargy 2 | 5
pallor 2 | 13
persistence of hyaloid vascula... 2 | 22
polydactyly 2 | 22
prenatal lethality 2 | 16
shortened RR interval 2 | 19
small thymus 2 | 11
thrombocytosis 2 | 23
tremors 2 | 34

Disease

ovarian cancer 298 | 8,491
osteosarcoma 240 | 7,933
psoriasis 234 | 6,685
medulloblastoma, large-cell 215 | 6,234
glioblastoma 201 | 5,572
lung cancer 163 | 4,473
atypical teratoid / rhabdoid tumor 158 | 4,369
Breast cancer 136 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 134 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 128 | 3,289
malignant mesothelioma 125 | 3,163
invasive ductal carcinoma 123 | 2,950
lung adenocarcinoma 121 | 2,714
intraductal papillary-mucinous carcinoma (IPMC) 119 | 2,988
primitive neuroectodermal tumor 108 | 3,031
oligodendroglioma 107 | 2,849
pilocytic astrocytoma 103 | 3,086
lung carcinoma 102 | 2,844
pediatric high grade glioma 102 | 2,712
ependymoma 100 | 2,514
astrocytic glioma 97 | 2,241
Carcinoma 89 | 2,147
colon cancer 86 | 1,475
subependymal giant cell astrocytoma 85 | 2,287
non-small cell lung cancer 84 | 2,798
pancreatic cancer 84 | 2,300
Cancer 83 | 2,346
interstitial cystitis 75 | 2,299
breast carcinoma 74 | 1,614
ulcerative colitis 74 | 2,087
Pick disease 73 | 1,893
pituitary cancer 72 | 1,972
ductal carcinoma in situ 71 | 1,745
cystic fibrosis 67 | 1,670
medulloblastoma 67 | 1,524
adrenocortical carcinoma 66 | 1,427
group 3 medulloblastoma 66 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 66 | 1,795
sonic hedgehog group medulloblastoma 65 | 1,482
adult high grade glioma 64 | 2,148
acute quadriplegic myopathy 61 | 1,157
Multiple myeloma 60 | 1,327
diabetes mellitus 59 | 1,663
primary pancreatic ductal adenocarcinoma 55 | 1,271
group 4 medulloblastoma 52 | 1,875
tuberculosis 52 | 1,563
astrocytoma 51 | 1,493
posterior fossa group B ependymoma 51 | 1,530
dermatomyositis 45 | 966
juvenile dermatomyositis 45 | 1,189
posterior fossa group A ependymoma 45 | 1,511
Heart disease 42 | 279
Obesity 41 | 616
Atopic dermatitis 39 | 944
gastric carcinoma 38 | 832
non primary Sjogren syndrome sicca 38 | 840
Duchenne muscular dystrophy 37 | 602
Rheumatoid Arthritis 36 | 1,170
active Crohn's disease 35 | 918
atypical teratoid/rhabdoid tumor 35 | 1,095
fibroadenoma 35 | 557
Down syndrome 34 | 548
Waldenstrons macroglobulinemia 34 | 764
Alzheimer's disease 33 | 644
aldosterone-producing adenoma 33 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 499
spina bifida 30 | 1,064
non-small cell lung carcinoma 29 | 413
cutaneous lupus erythematosus 28 | 1,056
hepatocellular carcinoma 25 | 550
tuberculosis and treatment for 6 months 25 | 686
active ulcerative colitis 24 | 477
acute myeloid leukemia 24 | 785
Atrial Fibrillation 23 | 110
Intellectual disability 23 | 573
nasopharyngeal carcinoma 23 | 1,056
pancreatic carcinoma 23 | 567
Endometriosis 22 | 535
Multiple Sclerosis 22 | 498
esophageal adenocarcinoma 22 | 737
Hypertension 21 | 293
mucosa-associated lymphoid tissue lymphoma 21 | 480
progressive supranuclear palsy 21 | 674
Amyotrophic Lateral Sclerosis 20 | 432
Schizophrenia 20 | 503
Vascular disease 20 | 281
interstitial lung disease 19 | 292
sarcoidosis 19 | 368
Asthma 18 | 349
Autistic Disorder 18 | 320
Kidney disease 18 | 397
Mammary Neoplasms 18 | 410
primary Sjogren syndrome 18 | 788
Cardiomyopathy 17 | 110
Epilepsy 17 | 346
chronic rhinosinusitis 17 | 512
non diabetic and post-ischemic heart failure 17 | 200
Neurodegenerative disease 16 | 383
Atherosclerosis 15 | 275
IGA Glomerulonephritis 15 | 454

Tissue

Male tissues 570 | 17,968
Nervous System 570 | 18,560
Digestive Tract 569 | 18,472
Blood and immune system 568 | 17,994
Cardiovascular System 568 | 17,957
Female tissues 568 | 18,646
Liver and Pancreas 568 | 18,135
Urinary Tract 568 | 18,443
Endocrine System 567 | 18,511
Skin and soft tissues 566 | 18,114
Respiratory system 561 | 17,483

Target Family

Non-IDG 298 | 11,969
Enzyme 145 | 4,146
Transcription Factor 37 | 1,400
Ion Channel 33 | 341
Kinase 21 | 634
Transporter 20 | 473
GPCR 13 | 408
Nuclear Receptor 8 | 48
Epigenetic 7 | 242

Jensen-KB Tissue

Heart 582 | 582
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
6-phosphogluconate dehydrogenase, decarboxylating PGD Tchem Enzyme -2.55417 348.6 173
Angiopoietin-related protein 2 ANGPTL2 Tbio Non-IDG -1.74019 67.9 132
Pyrin domain-containing protein 1 PYDC1 Tbio Non-IDG -2.87047 721.5 92
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.29937 33.0 142
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -1.97288 119.1 151
Ras GTPase-activating protein nGAP RASAL2 Tbio Enzyme -1.50499 28.6 91
Monocarboxylate transporter 1 SLC16A1 Tchem Transporter -2.42636 263.7 235
Transmembrane protein 182 TMEM182 Tdark Non-IDG -0.20165 1.84 9
Coiled-coil domain-containing protein 141 CCDC141 Tdark Non-IDG -0.61681 3.82 82
Band 4.1-like protein 2 EPB41L2 Tbio Non-IDG -1.34243 25.3 156