Development Level

Tbio 101 | 11,651
Tchem 23 | 1,388
Tclin 11 | 612
Tdark 4 | 6,593

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 5 | 278
increased lean body mass 4 | 172
decreased body weight 3 | 161
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
abnormal QT variability 1 | 10
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal incisor morphology 1 | 4
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cataract 1 | 92
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased granulocyte number 1 | 1
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
lordosis 1 | 1
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
vertebral transformation 1 | 12

Disease

ovarian cancer 110 | 8,520
Carcinoma 107 | 11,493
osteosarcoma 80 | 7,950
psoriasis 74 | 6,694
glioblastoma 66 | 5,792
medulloblastoma, large-cell 61 | 6,241
lung cancer 59 | 4,740
atypical teratoid / rhabdoid tumor 56 | 5,112
Cancer 53 | 2,499
Breast cancer 51 | 3,578
malignant mesothelioma 48 | 3,232
group 3 medulloblastoma 42 | 4,104
pancreatic cancer 41 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
ependymoma 37 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
lung adenocarcinoma 37 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
invasive ductal carcinoma 33 | 2,951
lung carcinoma 32 | 2,843
non-small cell lung cancer 32 | 2,890
Autosomal recessive predisposition 31 | 1,442
adult high grade glioma 31 | 3,801
Multiple myeloma 30 | 1,332
pituitary cancer 29 | 1,972
ulcerative colitis 28 | 1,819
cystic fibrosis 27 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
Astrocytoma, Pilocytic 26 | 3,081
Intellectual disability 26 | 1,016
Kidney cancer 24 | 2,613
primitive neuroectodermal tumor 24 | 3,035
tuberculosis 24 | 2,010
Short stature 23 | 531
primary pancreatic ductal adenocarcinoma 23 | 1,109
Dull intelligence 22 | 645
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
diabetes mellitus 22 | 1,728
interstitial cystitis 22 | 2,312
subependymal giant cell astrocytoma 21 | 2,287
Liver Cirrhosis, Experimental 20 | 769
Schizophrenia 20 | 1,160
Waldenstrons macroglobulinemia 19 | 765
breast carcinoma 19 | 1,638
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,855
colon cancer 18 | 1,478
gastric carcinoma 18 | 807
Cognitive delay 17 | 608
Down syndrome 17 | 499
Epilepsy 17 | 792
Failure to gain weight 17 | 365
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
Pediatric failure to thrive 17 | 365
Pick disease 17 | 1,894
astrocytic glioma 17 | 2,597
astrocytoma 17 | 1,146
juvenile dermatomyositis 17 | 1,187
non primary Sjogren syndrome sicca 17 | 891
oligodendroglioma 17 | 2,850
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
Seizures 16 | 596
acute quadriplegic myopathy 16 | 1,158
adrenocortical carcinoma 16 | 1,428
Acquired scoliosis 15 | 281
Curvature of spine 15 | 282
Alzheimer's disease 14 | 658
Atopic dermatitis 14 | 952
Duchenne muscular dystrophy 14 | 601
Muscle hypotonia 14 | 571
Bipolar Disorder 13 | 666
Depressive disorder 13 | 409
Neurodegenerative disease 13 | 414
Prostatic Neoplasms 13 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
dermatomyositis 13 | 966
esophageal adenocarcinoma 13 | 737
nasopharyngeal carcinoma 13 | 1,058
Feeding difficulties in infancy 12 | 175
Melanoma 12 | 711
Small head 12 | 374
fibroadenoma 12 | 559
pediatric high grade glioma 12 | 1,064
spina bifida 12 | 1,074
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Mental Depression 11 | 333
Micrognathism 11 | 275
Neoplasm Invasiveness 11 | 161
Neoplasm Metastasis 11 | 168
Osteoporosis 11 | 363
Rheumatoid arthritis 11 | 1,191
cutaneous lupus erythematosus 11 | 1,057
Becker muscular dystrophy 10 | 191
Cataract 10 | 297

Tissue

Blood and immune system 139 | 16,909
Digestive Tract 139 | 17,369
Endocrine System 139 | 18,159
Female tissues 139 | 17,400
Liver and Pancreas 139 | 16,750
Male tissues 139 | 17,142
Skin and soft tissues 139 | 17,230
Urinary Tract 139 | 16,678
Nervous System 138 | 16,725
Respiratory system 138 | 16,393
Cardiovascular System 137 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 34 | 4,145
Kinase 10 | 634
Transcription Factor 6 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 3 | 48
Ion Channel 2 | 344
Transporter 2 | 473
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Fibroblast 139 | 139
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
Suppressor of tumorigenicity 7 protein ST7 Tbio Non-IDG -1.48398 30.6 112
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Reversion-inducing cysteine-rich protein with Kazal motifs RECK Tbio Non-IDG -2.24752 194.4 192
RNA-binding motif, single-stranded-interacting protein 3 RBMS3 Tbio Non-IDG -0.93602 12.0 95
Integrin alpha-3 ITGA3 Tbio Non-IDG -2.08360 104.1 587
Sialidase-4 NEU4 Tchem Enzyme -1.39624 25.1 115
Acid ceramidase ASAH1 Tchem Enzyme -2.94716 848.0 203
TERF1-interacting nuclear factor 2 TINF2 Tbio Non-IDG -2.03707 99.1 138