Development Level

Tbio 95 | 10,625
Tchem 29 | 1,890
Tclin 11 | 602
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 10 | 633
preweaning lethality, incomple... 4 | 260
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
increased lean body mass 3 | 107
abnormal QRS complex 2 | 25
abnormal behavioral response t... 2 | 52
abnormal lens morphology 2 | 73
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating iron lev... 2 | 25
increased blood urea nitrogen ... 2 | 44
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
abnormal behavior 1 | 226
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/ hair morphology 1 | 18
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal incisor morphology 1 | 3
abnormal kidney morphology 1 | 30
abnormal neural tube closure 1 | 37
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 8
abnormal retinal inner nuclear... 1 | 5
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased lean body mass 1 | 195
decreased macrophage cell numb... 1 | 4
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
enlarged seminal vesicle 1 | 1
enlarged spleen 1 | 26
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired righting response 1 | 19
increased B cell number 1 | 23
increased Ly6C high monocyte n... 1 | 12
increased NK T cell number 1 | 11
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased gamma-delta T cell n... 1 | 16
increased granulocyte number 1 | 8
increased mature B cell number 1 | 12
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
premature death 1 | 5
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 110 | 8,484
osteosarcoma 80 | 7,933
psoriasis 74 | 6,685
glioblastoma 62 | 5,572
medulloblastoma, large-cell 61 | 6,234
lung cancer 55 | 4,466
Cancer 50 | 2,346
malignant mesothelioma 46 | 3,162
atypical teratoid / rhabdoid tumor 45 | 4,369
Breast cancer 42 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,988
pancreatic cancer 39 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
lung adenocarcinoma 37 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
invasive ductal carcinoma 33 | 2,950
lung carcinoma 32 | 2,844
non-small cell lung cancer 31 | 2,798
Multiple myeloma 30 | 1,327
group 4 medulloblastoma 30 | 1,875
pituitary cancer 29 | 1,972
ulcerative colitis 28 | 2,087
cystic fibrosis 27 | 1,665
primary pancreatic ductal adenocarcinoma 27 | 1,271
pilocytic astrocytoma 26 | 3,086
pediatric high grade glioma 24 | 2,712
primitive neuroectodermal tumor 24 | 3,031
Carcinoma 23 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
diabetes mellitus 22 | 1,663
interstitial cystitis 22 | 2,299
tuberculosis 22 | 1,557
subependymal giant cell astrocytoma 21 | 2,287
astrocytoma 20 | 1,493
ependymoma 20 | 2,514
Waldenstrons macroglobulinemia 19 | 765
adult high grade glioma 19 | 2,148
ductal carcinoma in situ 19 | 1,745
breast carcinoma 18 | 1,614
colon cancer 18 | 1,475
gastric carcinoma 18 | 832
Down syndrome 17 | 548
Pick disease 17 | 1,893
juvenile dermatomyositis 17 | 1,189
oligodendroglioma 17 | 2,849
sonic hedgehog group medulloblastoma 17 | 1,482
Mammary Neoplasms 16 | 410
acute quadriplegic myopathy 16 | 1,157
adrenocortical carcinoma 16 | 1,427
group 3 medulloblastoma 16 | 2,254
non primary Sjogren syndrome sicca 16 | 840
Duchenne muscular dystrophy 14 | 602
astrocytic glioma 14 | 2,241
atypical teratoid/rhabdoid tumor 14 | 1,095
posterior fossa group A ependymoma 14 | 1,511
Alzheimer's disease 13 | 644
Atopic dermatitis 13 | 944
Neurodegenerative disease 13 | 383
Prostatic Neoplasms 13 | 471
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
dermatomyositis 13 | 933
esophageal adenocarcinoma 13 | 737
nasopharyngeal carcinoma 13 | 1,056
posterior fossa group B ependymoma 13 | 1,530
fibroadenoma 12 | 557
spina bifida 12 | 1,064
Peripheral Neuropathy 11 | 303
Rheumatoid Arthritis 11 | 1,160
cutaneous lupus erythematosus 11 | 1,056
Atherosclerosis 10 | 275
Becker muscular dystrophy 10 | 187
Endometriosis 10 | 535
Neoplasm Metastasis 10 | 138
active Crohn's disease 10 | 918
aldosterone-producing adenoma 10 | 664
Cerebrovascular disease 9 | 231
Obesity 9 | 616
Polycystic Ovary Syndrome 9 | 332
interstitial lung disease 9 | 291
medulloblastoma 9 | 1,524
tuberculosis and treatment for 6 months 9 | 686
Colorectal Neoplasms 8 | 217
Intellectual disability 8 | 573
Liver carcinoma 8 | 217
Parkinson's disease 8 | 364
Schizophrenia 8 | 501
acute myeloid leukemia 8 | 780
inflammatory breast cancer 8 | 404
limb girdle muscular dystrophy 2A 8 | 156
pancreatic carcinoma 8 | 567
Autistic Disorder 7 | 320
Hypertension 7 | 287
Multiple Sclerosis 7 | 498
Myocardial Infarction 7 | 126
Neoplasm Invasiveness 7 | 127
non-small cell lung carcinoma 7 | 413
Major Depressive Disorder 6 | 106
Spontaneous abortion 6 | 108
hepatocellular carcinoma 6 | 532
primary Sjogren syndrome 6 | 789

Tissue

Blood and immune system 139 | 17,995
Cardiovascular System 139 | 17,958
Digestive Tract 139 | 18,473
Endocrine System 139 | 18,512
Female tissues 139 | 18,647
Liver and Pancreas 139 | 18,136
Male tissues 139 | 17,969
Nervous System 139 | 18,561
Respiratory system 139 | 17,484
Skin and soft tissues 139 | 18,115
Urinary Tract 139 | 18,444

Target Family

Non-IDG 78 | 11,971
Enzyme 34 | 4,146
Kinase 10 | 634
Transcription Factor 6 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 3 | 48
Ion Channel 2 | 341
Transporter 2 | 473
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Fibroblast 139 | 139
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.21092 1667.7 216
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.51978 332.6 298
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.79457 669.7 172
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.73777 56.3 29
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.77264 56.4 133
Serpin H1 SERPINH1 Tbio Non-IDG -3.13545 1424.1 295
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.82582 711.9 172