Development Level

Tbio 551 | 10,625
Tdark 193 | 7,003
Tchem 83 | 1,890
Tclin 25 | 602

Collection

Eligible Ion Channel Proteins 5 | 117
Eligible Kinase Proteins 4 | 134

IMPC Term

preweaning lethality, complete... 36 | 633
embryonic lethality prior to t... 16 | 187
decreased body weight 15 | 174
decreased total body fat amoun... 15 | 186
preweaning lethality, incomple... 14 | 260
decreased lean body mass 13 | 195
embryonic lethality prior to o... 11 | 148
abnormal behavior 10 | 226
abnormal embryo size 9 | 112
decreased circulating glucose ... 9 | 121
decreased grip strength 8 | 123
enlarged heart 8 | 111
increased circulating alkaline... 8 | 119
abnormal bone structure 7 | 131
decreased circulating HDL chol... 7 | 77
decreased circulating choleste... 7 | 85
decreased lumbar vertebrae num... 7 | 62
decreased prepulse inhibition 7 | 52
hyperactivity 7 | 108
increased lean body mass 7 | 107
increased mean corpuscular hem... 7 | 93
abnormal bone mineralization 6 | 55
abnormal heart morphology 6 | 51
abnormal retina morphology 6 | 100
decreased bone mineral content 6 | 157
decreased bone mineral density 6 | 126
decreased circulating serum al... 6 | 79
decreased circulating triglyce... 6 | 83
increased bone mineral content 6 | 92
increased or absent threshold ... 6 | 128
increased sacral vertebrae num... 6 | 62
abnormal retinal pigmentation 5 | 61
abnormal spleen morphology 5 | 36
decreased body length 5 | 108
decreased mean corpuscular vol... 5 | 50
hypoactivity 5 | 89
increased circulating choleste... 5 | 53
increased fasted circulating g... 5 | 68
increased grip strength 5 | 83
increased mean corpuscular vol... 5 | 91
prenatal lethality prior to he... 5 | 64
small testis 5 | 37
abnormal lens morphology 4 | 73
abnormal neural tube closure 4 | 37
decreased circulating alanine ... 4 | 53
decreased circulating alkaline... 4 | 41
decreased circulating chloride... 4 | 32
decreased rib number 4 | 59
embryonic growth retardation 4 | 28
increased circulating HDL chol... 4 | 63
increased circulating sodium l... 4 | 71
increased exploration in new e... 4 | 56
increased heart weight 4 | 37
increased startle reflex 4 | 38
short tibia 4 | 82
abnormal seminal vesicle morph... 3 | 47
abnormal sleep behavior 3 | 63
abnormal testis morphology 3 | 30
decreased KLRG1+ CD8 alpha bet... 3 | 8
decreased T cell number 3 | 31
decreased circulating LDL chol... 3 | 37
decreased circulating aspartat... 3 | 27
decreased circulating calcium ... 3 | 33
decreased circulating insulin ... 3 | 75
decreased circulating iron lev... 3 | 25
decreased circulating total pr... 3 | 41
decreased effector memory CD8-... 3 | 24
decreased eosinophil cell numb... 3 | 41
decreased fasted circulating g... 3 | 49
decreased hemoglobin content 3 | 53
decreased leukocyte cell numbe... 3 | 54
decreased mean corpuscular hem... 3 | 34
decreased startle reflex 3 | 48
improved glucose tolerance 3 | 56
increased B cell number 3 | 23
increased blood urea nitrogen ... 3 | 44
increased circulating chloride... 3 | 43
increased circulating creatini... 3 | 29
increased circulating phosphat... 3 | 24
increased circulating triglyce... 3 | 24
increased hemoglobin content 3 | 45
increased prepulse inhibition 3 | 21
thick ventricular wall 3 | 7
thrombocytosis 3 | 23
abnormal behavioral response t... 2 | 52
abnormal coat appearance 2 | 25
abnormal cranium morphology 2 | 32
abnormal tooth morphology 2 | 24
decreased circulating bilirubi... 2 | 14
decreased circulating glycerol... 2 | 19
decreased neutrophil cell numb... 2 | 37
decreased total retina thickne... 2 | 20
enlarged spleen 2 | 26
impaired glucose tolerance 2 | 52
increased circulating bilirubi... 2 | 16
increased circulating calcium ... 2 | 32
increased hematocrit 2 | 36
increased total body fat amoun... 2 | 57
straub tail 2 | 26
thin ventricular wall 2 | 5

Disease

ovarian cancer 460 | 8,484
osteosarcoma 401 | 7,933
medulloblastoma, large-cell 324 | 6,234
glioblastoma 301 | 5,572
psoriasis 296 | 6,685
lung cancer 243 | 4,466
atypical teratoid / rhabdoid tumor 221 | 4,369
primitive neuroectodermal tumor 168 | 3,031
malignant mesothelioma 161 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 157 | 3,289
ependymoma 152 | 2,514
pediatric high grade glioma 147 | 2,712
Breast cancer 146 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 144 | 2,988
oligodendroglioma 144 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 131 | 2,956
pilocytic astrocytoma 126 | 3,086
invasive ductal carcinoma 125 | 2,950
non-small cell lung cancer 125 | 2,798
group 3 medulloblastoma 121 | 2,254
lung adenocarcinoma 116 | 2,713
subependymal giant cell astrocytoma 115 | 2,287
Cancer 113 | 2,346
group 4 medulloblastoma 113 | 1,875
pancreatic cancer 109 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 107 | 1,795
adult high grade glioma 106 | 2,148
astrocytic glioma 103 | 2,241
Pick disease 102 | 1,893
Multiple myeloma 101 | 1,327
astrocytoma 99 | 1,493
lung carcinoma 96 | 2,844
ulcerative colitis 89 | 2,087
pituitary cancer 87 | 1,972
interstitial cystitis 85 | 2,299
sonic hedgehog group medulloblastoma 82 | 1,482
tuberculosis 82 | 1,557
diabetes mellitus 78 | 1,663
ductal carcinoma in situ 75 | 1,745
acute quadriplegic myopathy 73 | 1,157
breast carcinoma 73 | 1,614
Carcinoma 70 | 2,147
medulloblastoma 69 | 1,524
Rheumatoid Arthritis 65 | 1,160
atypical teratoid/rhabdoid tumor 65 | 1,095
cystic fibrosis 64 | 1,665
dermatomyositis 64 | 933
juvenile dermatomyositis 62 | 1,189
posterior fossa group A ependymoma 62 | 1,511
primary pancreatic ductal adenocarcinoma 62 | 1,271
adrenocortical carcinoma 60 | 1,427
colon cancer 59 | 1,475
posterior fossa group B ependymoma 56 | 1,530
Waldenstrons macroglobulinemia 49 | 765
spina bifida 49 | 1,064
Down syndrome 44 | 548
nasopharyngeal carcinoma 44 | 1,056
gastric carcinoma 42 | 832
non primary Sjogren syndrome sicca 41 | 840
Alzheimer's disease 38 | 644
Obesity 37 | 616
acute myeloid leukemia 37 | 780
tuberculosis and treatment for 6 months 37 | 686
esophageal adenocarcinoma 36 | 737
progressive supranuclear palsy 36 | 674
active Crohn's disease 35 | 918
Intellectual disability 33 | 573
cutaneous lupus erythematosus 33 | 1,056
Duchenne muscular dystrophy 32 | 602
primary Sjogren syndrome 32 | 789
fibroadenoma 31 | 557
pancreatic carcinoma 31 | 567
aldosterone-producing adenoma 30 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 499
Atopic dermatitis 29 | 944
IGA Glomerulonephritis 27 | 454
hepatocellular carcinoma 26 | 532
Neurodegenerative disease 24 | 383
Amyotrophic Lateral Sclerosis 23 | 431
Prostatic Neoplasms 22 | 471
active ulcerative colitis 22 | 477
Parkinson's disease 21 | 364
chronic rhinosinusitis 20 | 512
inflammatory breast cancer 20 | 404
Autistic Disorder 19 | 320
Multiple Sclerosis 19 | 498
Epilepsy 18 | 346
Polycystic Ovary Syndrome 18 | 332
Retinitis pigmentosa 18 | 153
Schizophrenia 18 | 501
gastric cancer 17 | 430
Kidney disease 16 | 396
Mammary Neoplasms 16 | 410
sarcoidosis 16 | 358
Endometriosis 15 | 535
Stomach Neoplasms 15 | 282
Diabetes Mellitus, Non-Insulin-Dependent 14 | 157
Metabolic syndrome X 14 | 155
Neuropathy 14 | 210
mucosa-associated lymphoid tissue lymphoma 14 | 480

Tissue

Digestive Tract 845 | 18,473
Nervous System 845 | 18,561
Female tissues 843 | 18,647
Cardiovascular System 840 | 17,958
Endocrine System 840 | 18,512
Liver and Pancreas 840 | 18,136
Male tissues 840 | 17,969
Urinary Tract 838 | 18,444
Blood and immune system 837 | 17,995
Skin and soft tissues 835 | 18,115
Respiratory system 828 | 17,484

Target Family

Non-IDG 465 | 11,971
Enzyme 222 | 4,146
Transcription Factor 72 | 1,400
Kinase 28 | 634
Transporter 25 | 473
Epigenetic 16 | 242
Ion Channel 13 | 341
GPCR 5 | 406
Nuclear Receptor 3 | 48
TF/Epigenetic 3 | 38

Jensen-KB Tissue

Eye 852 | 852
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
RNA pseudouridylate synthase domain-containing protein 3 RPUSD3 Tdark Enzyme 0.42 34
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Lysine-specific demethylase 3B KDM3B Tbio Epigenetic -0.92399 9.25 269
Equilibrative nucleoside transporter 4 SLC29A4 Tbio Transporter -1.79381 73.1 189
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120