Development Level

Tbio 599 | 11,651
Tdark 165 | 6,593
Tchem 67 | 1,388
Tclin 25 | 612

Collection

RFA-RM-18-021 9 | 328
Ion Channel: IDG Consortium (T... 5 | 99
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 62 | 979
preweaning lethality, incomple... 23 | 499
embryonic lethality prior to t... 22 | 278
embryonic lethality prior to o... 19 | 239
abnormal behavior 18 | 298
decreased total body fat amoun... 17 | 207
decreased body weight 16 | 161
abnormal bone structure 14 | 187
abnormal embryo size 13 | 220
abnormal heart morphology 12 | 162
hyperactivity 12 | 148
decreased lean body mass 11 | 135
enlarged heart 11 | 210
increased lean body mass 11 | 172
decreased vertical activity 10 | 208
increased circulating alkaline... 10 | 122
decreased circulating glucose ... 9 | 126
decreased prepulse inhibition 9 | 82
increased bone mineral content 9 | 108
decreased circulating choleste... 8 | 93
embryonic growth retardation 8 | 106
increased mean corpuscular hem... 8 | 96
abnormal lens morphology 7 | 81
decreased body length 7 | 101
decreased bone mineral content 7 | 151
increased or absent threshold ... 7 | 101
increased startle reflex 7 | 112
increased total body fat amoun... 7 | 134
prenatal lethality prior to he... 7 | 87
decreased circulating serum al... 6 | 82
decreased circulating triglyce... 6 | 79
decreased startle reflex 6 | 75
hypoactivity 6 | 132
increased circulating HDL chol... 6 | 80
male infertility 6 | 123
abnormal bone mineralization 5 | 38
abnormal neural tube closure 5 | 46
abnormal seminal vesicle morph... 5 | 114
abnormal spleen morphology 5 | 55
cataract 5 | 92
decreased caudal vertebrae num... 5 | 53
decreased circulating HDL chol... 5 | 68
decreased circulating alkaline... 5 | 46
decreased grip strength 5 | 116
decreased hemoglobin content 5 | 68
decreased mean corpuscular vol... 5 | 79
hydrometra 5 | 53
increased circulating choleste... 5 | 66
increased fasted circulating g... 5 | 76
increased heart weight 5 | 62
small superior vagus ganglion 5 | 74
small testis 5 | 58
abnormal embryo turning 4 | 31
abnormal kidney morphology 4 | 65
abnormal testis morphology 4 | 43
decreased circulating LDL chol... 4 | 38
decreased circulating chloride... 4 | 30
decreased heart left ventricle... 4 | 28
edema 4 | 59
impaired glucose tolerance 4 | 75
improved glucose tolerance 4 | 79
increased circulating sodium l... 4 | 71
increased hematocrit 4 | 46
increased mean corpuscular vol... 4 | 92
increased monocyte cell number 4 | 63
increased prepulse inhibition 4 | 32
abnormal behavioral response t... 3 | 66
abnormal cranium morphology 3 | 36
abnormal eye morphology 3 | 68
abnormal locomotor behavior 3 | 24
abnormal retina morphology 3 | 71
abnormal retinal blood vessel ... 3 | 26
abnormal retinal vasculature m... 3 | 27
abnormal sleep behavior 3 | 70
abnormal tooth morphology 3 | 24
absent startle reflex 3 | 24
anophthalmia 3 | 33
corneal opacity 3 | 32
decreased blood urea nitrogen ... 3 | 51
decreased bone mineral density 3 | 126
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating bilirubi... 3 | 19
decreased circulating calcium ... 3 | 36
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased circulating total pr... 3 | 49
decreased fasted circulating g... 3 | 65
decreased mean corpuscular hem... 3 | 50
decreased mean platelet volume 3 | 25
increased blood urea nitrogen ... 3 | 48
increased circulating chloride... 3 | 41
increased circulating creatini... 3 | 38
increased circulating glucose ... 3 | 24
increased circulating potassiu... 3 | 29
increased heart rate 3 | 23
pallor 3 | 34
short tibia 3 | 97
thin ventricular wall 3 | 24
thrombocytosis 3 | 27

Disease

Carcinoma 523 | 11,493
ovarian cancer 463 | 8,520
osteosarcoma 405 | 7,950
medulloblastoma, large-cell 329 | 6,241
glioblastoma 309 | 5,792
psoriasis 299 | 6,694
atypical teratoid / rhabdoid tumor 272 | 5,112
lung cancer 251 | 4,740
ependymoma 238 | 4,679
group 3 medulloblastoma 219 | 4,104
adult high grade glioma 187 | 3,801
primitive neuroectodermal tumor 172 | 3,035
malignant mesothelioma 164 | 3,232
Breast cancer 158 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 158 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 145 | 2,989
oligodendroglioma 144 | 2,850
Astrocytoma, Pilocytic 133 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 132 | 2,955
non-small cell lung cancer 129 | 2,890
invasive ductal carcinoma 127 | 2,951
astrocytic glioma 124 | 2,597
Cancer 119 | 2,499
lung adenocarcinoma 117 | 2,716
subependymal giant cell astrocytoma 117 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 114 | 1,962
pancreatic cancer 111 | 2,398
group 4 medulloblastoma 110 | 1,855
Kidney cancer 108 | 2,613
Pick disease 102 | 1,894
Multiple myeloma 99 | 1,332
tuberculosis 97 | 2,010
lung carcinoma 96 | 2,843
pituitary cancer 89 | 1,972
interstitial cystitis 86 | 2,312
diabetes mellitus 83 | 1,728
astrocytoma 78 | 1,146
ulcerative colitis 78 | 1,819
ductal carcinoma in situ 76 | 1,745
Autosomal recessive predisposition 74 | 1,442
breast carcinoma 74 | 1,638
acute quadriplegic myopathy 73 | 1,158
pediatric high grade glioma 69 | 1,064
Intellectual disability 67 | 1,016
Rheumatoid arthritis 67 | 1,191
cystic fibrosis 66 | 1,696
dermatomyositis 64 | 966
Schizophrenia 62 | 1,160
juvenile dermatomyositis 62 | 1,187
adrenocortical carcinoma 60 | 1,428
colon cancer 59 | 1,478
Epilepsy 58 | 792
primary pancreatic ductal adenocarcinoma 55 | 1,109
Seizures 51 | 596
spina bifida 51 | 1,074
Waldenstrons macroglobulinemia 49 | 765
Muscle hypotonia 46 | 571
nasopharyngeal carcinoma 44 | 1,058
Down syndrome 43 | 499
Bipolar Disorder 41 | 666
non primary Sjogren syndrome sicca 41 | 891
Dull intelligence 40 | 645
Low intelligence 40 | 645
Mental Retardation 40 | 645
Mental deficiency 40 | 645
Poor school performance 40 | 645
gastric carcinoma 40 | 807
Obesity 39 | 678
Alzheimer's disease 38 | 658
Cognitive delay 38 | 608
Global developmental delay 38 | 608
Mental and motor retardation 38 | 608
acute myeloid leukemia 38 | 783
Liver Cirrhosis, Experimental 36 | 769
esophageal adenocarcinoma 36 | 737
medulloblastoma 36 | 720
progressive supranuclear palsy 36 | 676
Short stature 35 | 531
active Crohn's disease 35 | 922
active ulcerative colitis 34 | 764
cutaneous lupus erythematosus 34 | 1,057
Depressive disorder 32 | 409
Duchenne muscular dystrophy 32 | 601
Nystagmus 31 | 317
fibroadenoma 31 | 559
primary Sjogren syndrome 31 | 735
aldosterone-producing adenoma 30 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 510
pancreatic carcinoma 30 | 562
Atopic dermatitis 29 | 952
Sensorineural Hearing Loss (disorder) 29 | 284
Neurodegenerative disease 28 | 414
Cataract 27 | 297
Retinitis Pigmentosa 26 | 226
Strabismus 26 | 270
hepatocellular carcinoma 26 | 547
Amyotrophic lateral sclerosis 25 | 451
sonic hedgehog group medulloblastoma 25 | 467
tuberculosis and treatment for 6 months 25 | 409
Cleft Palate 24 | 271

Tissue

Endocrine System 845 | 18,159
Digestive Tract 841 | 17,369
Skin and soft tissues 838 | 17,230
Female tissues 836 | 17,400
Male tissues 833 | 17,142
Nervous System 833 | 16,725
Blood and immune system 830 | 16,909
Liver and Pancreas 828 | 16,750
Urinary Tract 824 | 16,678
Respiratory system 817 | 16,393
Cardiovascular System 800 | 15,192

Target Family

Non-IDG 468 | 12,091
Enzyme 223 | 4,145
Transcription Factor 72 | 1,400
Kinase 28 | 634
Transporter 25 | 473
Epigenetic 16 | 242
Ion Channel 13 | 344
GPCR 5 | 408
Nuclear Receptor 3 | 48
TF/Epigenetic 3 | 38

Jensen-KB Tissue

Eye 856 | 856
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Uncharacterized protein ZSWIM9 ZSWIM9 Tdark Non-IDG 0.00000 12
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Echinoderm microtubule-associated protein-like 5 EML5 Tdark Non-IDG -0.47268 3.14 28
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Homeobox protein SIX6 SIX6 Tbio Transcription Factor -2.23077 163.2 112
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204
Protein phosphatase 1 regulatory subunit 15B PPP1R15B Tbio Enzyme -1.42081 25.8 85