Development Level

Tbio 17 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased total body fat amoun... 3 | 134
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
hyperactivity 2 | 148
increased lean body mass 2 | 172
trunk curl 2 | 16
abnormal behavior 1 | 298
abnormal glucose homeostasis 1 | 4
abnormal limb position 1 | 3
abnormal locomotor activation 1 | 16
abnormal pelvic girdle bone mo... 1 | 12
abnormal skin morphology 1 | 50
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8
stereotypic behavior 1 | 3
thin skin 1 | 2
thrombocytosis 1 | 27

Disease

Carcinoma 20 | 11,493
osteosarcoma 14 | 7,950
medulloblastoma, large-cell 12 | 6,241
ovarian cancer 12 | 8,520
Breast cancer 9 | 3,578
Cancer 9 | 2,499
atypical teratoid / rhabdoid tumor 9 | 5,112
psoriasis 9 | 6,694
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
lung cancer 7 | 4,740
Autosomal recessive predisposition 6 | 1,442
interstitial cystitis 6 | 2,312
pancreatic cancer 6 | 2,398
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
nasopharyngeal carcinoma 5 | 1,058
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Cataract 4 | 297
Kidney cancer 4 | 2,613
Melanoma 4 | 711
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Acanthosis Nigricans 3 | 27
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Myopia 3 | 176
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Seizures 3 | 596
breast carcinoma 3 | 1,638
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972
Atopic dermatitis 2 | 952
Carcinoma, Hepatocellular 2 | 228
Cerebellar Ataxia 2 | 304
Clubfoot 2 | 39
Disease Progression 2 | 136
Fatigue 2 | 182
Gynecomastia 2 | 64
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypotrichosis 2 | 47
Impaired cognition 2 | 96
Insulin Resistance 2 | 72
Irregular hyperpigmentation 2 | 33
LEOPARD syndrome 2 | 20
Liver carcinoma 2 | 240
Mental impairment 2 | 95
Multiple myeloma 2 | 1,332
Noonan syndrome 2 | 34
Obesity 2 | 678
Ovarian Neoplasms 2 | 102
Papilloma 2 | 44
Pulmonary embolism 2 | 55
Recurrent respiratory infections 2 | 141
Sensorineural Hearing Loss (disorder) 2 | 284
Skin cancer 2 | 469
Squamous cell carcinoma 2 | 129
Strabismus 2 | 270
adrenocortical carcinoma 2 | 1,428
dermatomyositis 2 | 966
group 3 medulloblastoma 2 | 4,104
oligodendroglioma 2 | 2,850
ovarian neoplasm 2 | 99
sarcoidosis 2 | 370
Aqueductal Stenosis 1 | 5
DEAFNESS, AUTOSOMAL RECESSIVE 2 1 | 1
Deafness, Autosomal Dominant 11 1 | 1
Stargardt disease 1 | 6

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Urinary Tract 26 | 16,678
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Kinase 2 | 634
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transporter 1 | 473

Jensen-KB Tissue

Epithelium 27 | 27
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 638 ZNF638 Tbio Non-IDG -0.68946 6.04 67
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Radial spoke head protein 3 homolog RSPH3 Tdark Non-IDG -1.14197 12.4 28
Rho guanine nucleotide exchange factor 5 ARHGEF5 Tbio Non-IDG -0.48804 5.75 249
Choline transporter-like protein 2 SLC44A2 Tbio Transporter -1.62474 40.3 92
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 ALKBH4 Tdark Enzyme -0.51663 4.07 103
Nascent polypeptide-associated complex subunit alpha-2 NACA2 Tdark Non-IDG -1.79894 58.8 27
Zinc finger protein 672 ZNF672 Tdark Transcription Factor 0.56 0.13 100
Zinc finger protein 768 ZNF768 Tdark Transcription Factor 1.00 0.04 105
Caveolae-associated protein 3 CAVIN3 Tbio Enzyme -1.39796 28.7 150