Development Level

Tbio 38 | 11,445
Tchem 10 | 1,598
Tdark 7 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased lean body mass 2 | 135
increased circulating HDL chol... 2 | 80
increased circulating triglyce... 2 | 42
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal ovary morphology 1 | 7
absent epididymis 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
short tibia 1 | 97
small adrenal glands 1 | 16
tremors 1 | 39

Disease

Carcinoma 45 | 11,493
osteosarcoma 35 | 7,950
ovarian cancer 34 | 8,520
glioblastoma 29 | 5,792
lung cancer 27 | 4,740
atypical teratoid / rhabdoid tumor 26 | 5,112
medulloblastoma, large-cell 26 | 6,241
malignant mesothelioma 23 | 3,232
psoriasis 22 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
non-small cell lung cancer 19 | 2,890
pancreatic cancer 19 | 2,398
invasive ductal carcinoma 18 | 2,951
lung carcinoma 18 | 2,843
adult high grade glioma 17 | 3,801
ependymoma 17 | 4,679
interstitial cystitis 17 | 2,312
Astrocytoma, Pilocytic 16 | 3,081
Breast cancer 16 | 3,578
Cancer 16 | 2,499
primitive neuroectodermal tumor 16 | 3,035
group 4 medulloblastoma 15 | 1,855
lung adenocarcinoma 15 | 2,716
ulcerative colitis 15 | 1,819
tuberculosis 14 | 2,010
cystic fibrosis 12 | 1,696
group 3 medulloblastoma 12 | 4,104
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
Kidney cancer 10 | 2,613
astrocytic glioma 10 | 2,597
breast carcinoma 10 | 1,638
adrenocortical carcinoma 9 | 1,428
cutaneous lupus erythematosus 9 | 1,057
ductal carcinoma in situ 9 | 1,745
oligodendroglioma 9 | 2,850
primary pancreatic ductal adenocarcinoma 9 | 1,109
diabetes mellitus 8 | 1,728
juvenile dermatomyositis 8 | 1,187
spina bifida 8 | 1,074
Asthma 7 | 385
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
Coronary artery disease 6 | 268
Endometriosis 6 | 540
Liver Cirrhosis, Experimental 6 | 769
Multiple myeloma 6 | 1,332
astrocytoma 6 | 1,146
dermatomyositis 6 | 966
Allergic rhinitis 5 | 94
Breast Neoplasms 5 | 445
Cerebrovascular disease 5 | 238
Intellectual disability 5 | 1,016
Mammary Neoplasms 5 | 425
Rheumatoid arthritis 5 | 1,191
Vascular disease 5 | 319
active Crohn's disease 5 | 922
adrenocortical adenoma 5 | 131
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
progressive supranuclear palsy 5 | 676
sarcoidosis 5 | 370
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Dermatitis 4 | 157
Diarrhea 4 | 253
Epilepsy 4 | 792
Hypertension 4 | 396
Hypertensive disease 4 | 292
Lung disease 4 | 142
Seizures 4 | 596
acute myeloid leukemia 4 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
non diabetic and post-ischemic heart failure 4 | 200
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
posterior fossa group A ependymoma 4 | 468
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467
Allergic hypersensitivity disease 3 | 126
Arthritis 3 | 290
Atherosclerosis 3 | 291
Crohn's disease 3 | 321
Duchenne muscular dystrophy 3 | 601
Kidney disease 3 | 430
Malaria 3 | 160
chronic rhinosinusitis 3 | 512
hepatocellular carcinoma 3 | 547
nephrosclerosis 3 | 333

Tissue

Blood and immune system 56 | 16,909
Digestive Tract 56 | 17,369
Endocrine System 56 | 18,159
Female tissues 56 | 17,400
Male tissues 56 | 17,142
Nervous System 56 | 16,725
Respiratory system 56 | 16,393
Skin and soft tissues 56 | 17,230
Cardiovascular System 55 | 15,192
Liver and Pancreas 55 | 16,750
Urinary Tract 55 | 16,678

Target Family

Non-IDG 32 | 12,091
Enzyme 15 | 4,145
Transcription Factor 4 | 1,400
Kinase 3 | 634
GPCR 2 | 408
Transporter 1 | 473

Jensen-KB Tissue

Endothelial cell 57 | 57
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Vascular cell adhesion protein 1 VCAM1 Tchem Non-IDG -3.55044 3444.1 1291
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Protein-glutamine gamma-glutamyltransferase 2 TGM2 Tchem Enzyme -3.22049 1602.3 843
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
Cadherin-5 CDH5 Tbio Non-IDG -2.98207 896.8 731
Interleukin-33 IL33 Tbio Non-IDG -2.86989 870.0 754
C-X-C chemokine receptor type 3 CXCR3 Tchem GPCR -2.92733 849.1 650
Platelet glycoprotein Ib alpha chain GP1BA Tbio Non-IDG -2.80981 615.6 623