Development Level

Tbio 92 | 11,445
Tdark 32 | 6,588
Tchem 11 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 14 | 979
decreased total body fat amoun... 6 | 207
decreased body length 5 | 101
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
increased lean body mass 4 | 172
decreased bone mineral content 3 | 151
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased grip strength 3 | 116
embryonic lethality prior to o... 3 | 239
increased bone mineral content 3 | 108
increased mean corpuscular hem... 3 | 96
preweaning lethality, incomple... 3 | 499
abnormal lung morphology 2 | 26
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating potassiu... 2 | 20
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
edema 2 | 59
embryonic growth retardation 2 | 106
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased grip strength 2 | 41
increased monocyte cell number 2 | 63
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal forebrain development 1 | 20
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal limb position 1 | 3
abnormal lip morphology 1 | 2
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QRS complex duration 1 | 8
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
stereotypic behavior 1 | 3
thin skin 1 | 2
thrombocytopenia 1 | 56
trunk curl 1 | 16
urinary bladder obstruction 1 | 4

Disease

Carcinoma 85 | 11,493
ovarian cancer 78 | 8,520
osteosarcoma 77 | 7,950
medulloblastoma, large-cell 54 | 6,241
psoriasis 49 | 6,694
glioblastoma 48 | 5,792
atypical teratoid / rhabdoid tumor 43 | 5,112
ependymoma 39 | 4,679
lung cancer 38 | 4,740
malignant mesothelioma 32 | 3,232
group 3 medulloblastoma 29 | 4,104
adult high grade glioma 28 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
oligodendroglioma 27 | 2,850
primitive neuroectodermal tumor 27 | 3,035
Astrocytoma, Pilocytic 26 | 3,081
invasive ductal carcinoma 25 | 2,951
Kidney cancer 24 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
Breast cancer 23 | 3,578
Pick disease 22 | 1,894
astrocytic glioma 22 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
pituitary cancer 20 | 1,972
group 4 medulloblastoma 19 | 1,855
non-small cell lung cancer 19 | 2,890
lung adenocarcinoma 18 | 2,716
lung carcinoma 16 | 2,843
Intellectual disability 15 | 1,016
cystic fibrosis 15 | 1,696
Autosomal recessive predisposition 14 | 1,442
Rheumatoid arthritis 14 | 1,191
breast carcinoma 14 | 1,638
pancreatic cancer 14 | 2,398
Multiple myeloma 13 | 1,332
interstitial cystitis 13 | 2,312
subependymal giant cell astrocytoma 13 | 2,287
diabetes mellitus 12 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Cancer 11 | 2,499
astrocytoma 11 | 1,146
ductal carcinoma in situ 11 | 1,745
juvenile dermatomyositis 11 | 1,187
Liver cancer 10 | 604
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
colon cancer 10 | 1,478
Neuropathy 9 | 261
ulcerative colitis 9 | 1,819
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Neurodegenerative disease 8 | 414
Poor school performance 8 | 645
progressive supranuclear palsy 8 | 676
tuberculosis 8 | 2,010
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Muscle hypotonia 7 | 571
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
dermatomyositis 7 | 966
hereditary spastic paraplegia 7 | 318
pediatric high grade glioma 7 | 1,064
Obesity 6 | 678
cutaneous lupus erythematosus 6 | 1,057
gastric cancer 6 | 459
posterior fossa group A ependymoma 6 | 468
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
tuberculosis and treatment for 6 months 6 | 409
Absent reflex 5 | 92
Absent tendon reflex 5 | 92
Amyotrophic lateral sclerosis 5 | 451
Bipolar Disorder 5 | 666
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Lung Neoplasms 5 | 232
Reflex, Deep Tendon, Absent 5 | 92
Small head 5 | 374
active ulcerative colitis 5 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
Acquired scoliosis 4 | 281
Asthma 4 | 385
Atopic dermatitis 4 | 952
Curvature of spine 4 | 282
Epilepsy 4 | 792
Hyperreflexia 4 | 209
Optic Atrophy 4 | 242
Orbital separation excessive 4 | 244
active Crohn's disease 4 | 922
aldosterone-producing adenoma 4 | 665
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
pancreatic carcinoma 4 | 562

Tissue

Digestive Tract 132 | 17,369
Endocrine System 132 | 18,159
Female tissues 131 | 17,400
Male tissues 131 | 17,142
Nervous System 131 | 16,725
Blood and immune system 130 | 16,909
Liver and Pancreas 130 | 16,750
Skin and soft tissues 130 | 17,230
Respiratory system 129 | 16,393
Urinary Tract 129 | 16,678
Cardiovascular System 126 | 15,192

Target Family

Non-IDG 76 | 12,091
Enzyme 38 | 4,145
Transcription Factor 12 | 1,400
Transporter 5 | 473
Epigenetic 3 | 242
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Duodenum 136 | 136
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UPF0606 protein KIAA1549 KIAA1549 Tbio Non-IDG -1.67668 47.8 19
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Zinc transporter ZIP3 SLC39A3 Tbio Transporter -0.52290 3.15 87
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Membrane progestin receptor alpha PAQR7 Tbio Non-IDG -1.89212 76.1 122
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.39993 250.5 121
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Transmembrane prolyl 4-hydroxylase P4HTM Tchem Enzyme -2.70235 473.8 159
Myotubularin-related protein 13 SBF2 Tbio Non-IDG -1.38747 24.7 15
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.96016 82.2 167