Development Level

Tbio 21 | 11,651
Tdark 7 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 3 | 161
abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased cornea thickness 1 | 2
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 41
increased circulating serum al... 1 | 22
increased cornea thickness 1 | 1
increased erythrocyte cell num... 1 | 39
increased granulocyte number 1 | 1
increased heart weight 1 | 62
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small adrenal glands 1 | 16
small thymus 1 | 16
syndactyly 1 | 23
thin ventricular wall 1 | 24
trunk curl 1 | 16

Disease

ovarian cancer 22 | 8,520
Carcinoma 17 | 11,493
osteosarcoma 14 | 7,950
glioblastoma 13 | 5,792
group 3 medulloblastoma 12 | 4,104
atypical teratoid / rhabdoid tumor 11 | 5,112
Breast cancer 9 | 3,578
lung cancer 9 | 4,740
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
primary pancreatic ductal adenocarcinoma 7 | 1,109
primitive neuroectodermal tumor 7 | 3,035
acute myeloid leukemia 6 | 783
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
Cancer 5 | 2,499
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
Kidney cancer 4 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Multiple myeloma 3 | 1,332
Prostatic Neoplasms 3 | 495
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
sarcoidosis 3 | 370
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Chemical and Drug Induced Liver Injury 2 | 195
Disease Models, Animal 2 | 155
Duchenne muscular dystrophy 2 | 601
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Methylmalonic acidemia 2 | 37
Neoplasm Metastasis 2 | 168
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Reperfusion Injury 2 | 86
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 547
interstitial lung disease 2 | 298
lung carcinoma 2 | 2,843
posterior fossa group A ependymoma 2 | 468
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Adenocarcinoma of lung 1 | 142
Alcoholic Intoxication, Chronic 1 | 289
Brain Ischemia 1 | 110
Breast Neoplasms 1 | 445
Cardiovascular system disease 1 | 246
Cholestasis 1 | 155
Degenerative polyarthritis 1 | 115
Dystonia 1 | 164
ENSP00000256078 1 | 30
Endometrial Neoplasms 1 | 55
Endometrial cancer 1 | 311
Gaucher disease type 1 1 | 180
Hyperphosphatemia 1 | 32
Infertility 1 | 188
Lipid metabolism disorder 1 | 114
Liver Cirrhosis 1 | 181
Mammary Neoplasms 1 | 425
Megaloblastic anemia 1 | 18
Mesothelioma, Malignant 1 | 105
Motor neuron disease 1 | 49
Multiple Sclerosis 1 | 540
Narcolepsy 1 | 72
Neoplasm Invasiveness 1 | 161
Neurodegenerative Disorders 1 | 79
Obstructive sleep apnea 1 | 26
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Parkinson's disease 1 | 392
Pneumonia 1 | 174
Retinal Diseases 1 | 55
Severe combined immunodeficiency 1 | 51
Systemic lupus erythematosus 1 | 194
Vitamin B12 deficiency 1 | 20
Weight Gain 1 | 100
X-linked nonsyndromic deafness 1 | 12
glioblastoma multiforme 1 | 142
head and neck cancer and chronic obstructive pulmonary disease 1 | 239

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 3 | 4,145
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

Jensen-KB Tissue

Coronary artery 31 | 31
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Max dimerization protein 3 MXD3 Tbio Transcription Factor -2.04549 108.3 184
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
Cleavage stimulation factor subunit 2 tau variant CSTF2T Tbio Non-IDG -0.87334 8.94 128
Speckle-type POZ protein SPOP Tbio Non-IDG -1.87490 83.8 138
Protein ABHD18 ABHD18 Tdark Non-IDG 0.00000 61
Stromelysin-2 MMP10 Tchem Non-IDG -2.36668 224.6 449
Nucleoside diphosphate kinase 6 NME6 Tbio Kinase -0.78058 6.17 131
Osteoclast-stimulating factor 1 OSTF1 Tbio Non-IDG -1.84940 62.3 155
Proline-rich AKT1 substrate 1 AKT1S1 Tchem Non-IDG -2.25755 174.2 434