Development Level

Tbio 21 | 10,625
Tdark 6 | 7,003
Tchem 3 | 1,890

IMPC Phenotype

preweaning lethality, complete... 4 | 633
abnormal embryo size 2 | 112
decreased body weight 2 | 174
embryonic lethality prior to t... 2 | 187
abnormal QRS complex 1 | 25
abnormal radius morphology 1 | 8
abnormal skin appearance 1 | 8
decreased Ly6C high monocyte n... 1 | 18
decreased body length 1 | 108
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
increased blood uric acid leve... 1 | 5
increased circulating chloride... 1 | 43
increased erythrocyte cell num... 1 | 26
increased granulocyte number 1 | 8
increased heart weight 1 | 37
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
short tibia 1 | 82
small adrenal glands 1 | 15
small thymus 1 | 11
thick ventricular wall 1 | 7
trunk curl 1 | 15

Disease

ovarian cancer 22 | 8,491
osteosarcoma 14 | 7,933
glioblastoma 13 | 5,572
atypical teratoid / rhabdoid tumor 10 | 4,369
lung cancer 9 | 4,473
group 3 medulloblastoma 8 | 2,254
medulloblastoma, large-cell 8 | 6,234
psoriasis 8 | 6,685
Breast cancer 7 | 3,098
malignant mesothelioma 7 | 3,163
pediatric high grade glioma 7 | 2,712
primary pancreatic ductal adenocarcinoma 7 | 1,271
primitive neuroectodermal tumor 7 | 3,031
acute myeloid leukemia 6 | 785
invasive ductal carcinoma 6 | 2,950
lung adenocarcinoma 6 | 2,714
pancreatic cancer 6 | 2,300
acute quadriplegic myopathy 5 | 1,157
astrocytic glioma 5 | 2,241
colon cancer 5 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
non-small cell lung cancer 5 | 2,798
Cancer 4 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
juvenile dermatomyositis 4 | 1,189
ulcerative colitis 4 | 2,087
Multiple myeloma 3 | 1,327
Prostatic Neoplasms 3 | 471
adult high grade glioma 3 | 2,148
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,670
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
non primary Sjogren syndrome sicca 3 | 840
oligodendroglioma 3 | 2,849
posterior fossa group A ependymoma 3 | 1,511
sarcoidosis 3 | 368
sonic hedgehog group medulloblastoma 3 | 1,482
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic Lateral Sclerosis 2 | 432
Carcinoma 2 | 2,147
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Methylmalonic acidemia 2 | 39
Neoplasm Metastasis 2 | 138
Pick disease 2 | 1,893
Polycystic Ovary Syndrome 2 | 334
Reperfusion Injury 2 | 84
Stomach Neoplasms 2 | 282
Waldenstrons macroglobulinemia 2 | 764
adrenocortical carcinoma 2 | 1,427
esophageal adenocarcinoma 2 | 737
hepatocellular carcinoma 2 | 550
interstitial lung disease 2 | 292
lung carcinoma 2 | 2,844
pilocytic astrocytoma 2 | 3,086
posterior fossa group B ependymoma 2 | 1,530
Atopic dermatitis 1 | 944
Cardiovascular system disease 1 | 194
Cataract 1 | 104
Degenerative polyarthritis 1 | 93
Dystonia 1 | 77
Endometrial Neoplasms 1 | 50
Epilepsy 1 | 346
Gaucher disease type 1 1 | 171
Hyperphosphatemia 1 | 32
IGA Glomerulonephritis 1 | 454
Infertility 1 | 163
Lipid metabolism disorder 1 | 102
Lung Neoplasms 1 | 171
Male infertility 1 | 170
Mammary Neoplasms 1 | 410
Megaloblastic anemia 1 | 18
Microphthalmia 1 | 79
Motor neuron disease 1 | 39
Multiple Sclerosis 1 | 498
Narcolepsy 1 | 69
Osteoporosis 1 | 259
Parkinson's disease 1 | 364
Pneumonia 1 | 133
Prostate cancer 1 | 172
Severe Combined Immunodeficiency 1 | 46
Vitamin B12 deficiency 1 | 20
Weight Gain 1 | 87
atypical teratoid/rhabdoid tumor 1 | 1,095
chronic rhinosinusitis 1 | 512
fibroadenoma 1 | 557
glioblastoma multiforme 1 | 347
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
inflammatory breast cancer 1 | 404
limb girdle muscular dystrophy 2A 1 | 156
medulloblastoma 1 | 1,524
pancreatic carcinoma 1 | 567
progressive supranuclear palsy 1 | 674
systemic lupus erythematosus 1 | 172
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 30 | 17,994
Cardiovascular System 30 | 17,957
Digestive Tract 30 | 18,472
Endocrine System 30 | 18,511
Female tissues 30 | 18,646
Liver and Pancreas 30 | 18,135
Male tissues 30 | 17,968
Nervous System 30 | 18,560
Respiratory system 30 | 17,483
Skin and soft tissues 30 | 18,114
Urinary Tract 30 | 18,443

Target Family

Non-IDG 23 | 11,969
Enzyme 3 | 4,146
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

Jensen-KB Tissue

Coronary artery 30 | 30
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.67147 456.7 712
NF-X1-type zinc finger protein NFXL1 NFXL1 Tdark Transcription Factor -0.63682 4.31 14
Max dimerization protein 3 MXD3 Tbio Transcription Factor -1.94326 83.1 160
Beta-catenin-like protein 1 CTNNBL1 Tbio Non-IDG -3.16233 1413.4 197
Stromelysin-2 MMP10 Tchem Non-IDG -2.34325 213.8 372
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 KCTD10 Tbio Non-IDG -0.78210 8.37 75
Nucleoside diphosphate kinase 6 NME6 Tbio Kinase -0.78058 6.16 115
Cleavage stimulation factor subunit 2 tau variant CSTF2T Tbio Non-IDG -0.86156 8.94 118
Poly [ADP-ribose] polymerase 6 PARP6 Tchem Enzyme -0.61455 3.45 126
Protein YIPF5 YIPF5 Tbio Non-IDG -1.25013 16.0 68