Development Level

Tbio 60 | 10,625
Tchem 13 | 1,890
Tclin 4 | 602
Tdark 4 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to t... 4 | 187
embryonic lethality prior to o... 3 | 148
increased grip strength 2 | 83
abnormal allantois morphology 1 | 3
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digit morphology 1 | 13
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal limb bud morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retina morphology 1 | 100
abnormal startle reflex 1 | 14
abnormal tail bud morphology 1 | 6
corneal opacity 1 | 25
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased heart weight 1 | 44
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
fused cornea and lens 1 | 4
fused phalanges 1 | 1
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating glucose ... 1 | 16
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
persistence of hyaloid vascula... 1 | 22
preweaning lethality, incomple... 1 | 260
shortened QT interval 1 | 4
small adrenal glands 1 | 15
small spleen 1 | 11
thrombocytopenia 1 | 46

Disease

ovarian cancer 48 | 8,484
psoriasis 37 | 6,685
lung cancer 35 | 4,466
glioblastoma 34 | 5,572
medulloblastoma, large-cell 30 | 6,234
osteosarcoma 27 | 7,933
Cancer 25 | 2,346
atypical teratoid / rhabdoid tumor 25 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
lung adenocarcinoma 21 | 2,713
pediatric high grade glioma 21 | 2,712
non-small cell lung cancer 20 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
Multiple myeloma 17 | 1,327
Waldenstrons macroglobulinemia 17 | 765
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
malignant mesothelioma 15 | 3,162
pancreatic cancer 15 | 2,300
primitive neuroectodermal tumor 15 | 3,031
Breast cancer 14 | 3,094
colon cancer 14 | 1,475
invasive ductal carcinoma 14 | 2,950
pituitary cancer 14 | 1,972
diabetes mellitus 13 | 1,663
pilocytic astrocytoma 12 | 3,086
cystic fibrosis 11 | 1,665
group 3 medulloblastoma 11 | 2,254
sonic hedgehog group medulloblastoma 11 | 1,482
acute quadriplegic myopathy 10 | 1,157
lung carcinoma 10 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
posterior fossa group A ependymoma 10 | 1,511
primary pancreatic ductal adenocarcinoma 10 | 1,271
IGA Glomerulonephritis 9 | 454
Mammary Neoplasms 9 | 410
adrenocortical carcinoma 9 | 1,427
astrocytoma 9 | 1,493
ductal carcinoma in situ 9 | 1,745
non primary Sjogren syndrome sicca 9 | 840
subependymal giant cell astrocytoma 9 | 2,287
inflammatory breast cancer 8 | 404
interstitial cystitis 8 | 2,299
oligodendroglioma 8 | 2,849
ulcerative colitis 8 | 2,087
Carcinoma 7 | 2,147
Stomach Neoplasms 7 | 282
adult high grade glioma 7 | 2,148
group 4 medulloblastoma 7 | 1,875
medulloblastoma 7 | 1,524
nasopharyngeal carcinoma 7 | 1,056
tuberculosis 7 | 1,557
Atopic dermatitis 6 | 944
Duchenne muscular dystrophy 6 | 602
Liver carcinoma 6 | 217
Vascular disease 6 | 281
active Crohn's disease 6 | 918
atypical teratoid/rhabdoid tumor 6 | 1,095
ependymoma 6 | 2,514
hepatocellular carcinoma 6 | 532
Colonic Neoplasms 5 | 126
Colorectal Neoplasms 5 | 217
Intellectual disability 5 | 573
Kidney disease 5 | 396
Osteoporosis 5 | 257
Prostatic Neoplasms 5 | 471
Squamous cell carcinoma 5 | 94
astrocytic glioma 5 | 2,241
breast carcinoma 5 | 1,614
cutaneous lupus erythematosus 5 | 1,056
dermatomyositis 5 | 933
mucosa-associated lymphoid tissue lymphoma 5 | 480
Anemia 4 | 252
Barrett's esophagus 4 | 183
Diamond-Blackfan anemia 4 | 28
Down syndrome 4 | 548
Endometriosis 4 | 535
Epilepsy 4 | 346
Esophageal Neoplasms 4 | 67
Leukemia, Myelocytic, Acute 4 | 113
Liver neoplasms 4 | 109
Lung Neoplasms 4 | 171
Melanoma 4 | 261
Neoplasm Invasiveness 4 | 127
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,160
Weight Gain 4 | 87
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 430
gastric carcinoma 4 | 832
Adenoma 3 | 165
Becker muscular dystrophy 3 | 187
Disease Progression 3 | 125
Heart disease 3 | 279
Inflammatory bowel disease 3 | 142
Myocardial Ischemia 3 | 169
Pancreatic Neoplasm 3 | 79
acute myeloid leukemia 3 | 780
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
spina bifida 3 | 1,064

Tissue

Blood and immune system 79 | 17,995
Cardiovascular System 79 | 17,958
Digestive Tract 79 | 18,473
Endocrine System 79 | 18,512
Female tissues 79 | 18,647
Liver and Pancreas 79 | 18,136
Male tissues 79 | 17,969
Nervous System 79 | 18,561
Respiratory system 79 | 17,484
Urinary Tract 79 | 18,444
Skin and soft tissues 78 | 18,115

Target Family

Non-IDG 48 | 11,971
Enzyme 21 | 4,146
Transcription Factor 4 | 1,400
Transporter 4 | 473
GPCR 1 | 406
Ion Channel 1 | 341
Kinase 1 | 634
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Colonic adenocarcinoma cell 81 | 81
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.69547 474.2 685
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.77086 576.3 300
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.42381 27.6 27
Palmitoleoyl-protein carboxylesterase NOTUM NOTUM Tchem Enzyme -2.17902 149.5 98
Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 Tbio Non-IDG -2.42637 343.3 423
Glycogen phosphorylase, brain form PYGB Tbio Enzyme -1.96208 92.3 345