Development Level

Tbio 63 | 11,651
Tchem 10 | 1,388
Tclin 4 | 612
Tdark 4 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
decreased circulating creatini... 2 | 39
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain morphology 1 | 10
abnormal head morphology 1 | 10
abnormal heart looping 1 | 5
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal neural tube morpholog... 1 | 12
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tail bud morphology 1 | 8
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased hemoglobin content 1 | 68
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small spleen 1 | 19
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

ovarian cancer 48 | 8,520
Carcinoma 43 | 11,493
psoriasis 37 | 6,694
lung cancer 35 | 4,740
glioblastoma 34 | 5,792
medulloblastoma, large-cell 30 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
osteosarcoma 27 | 7,950
Cancer 26 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
lung adenocarcinoma 21 | 2,716
group 3 medulloblastoma 20 | 4,104
non-small cell lung cancer 20 | 2,890
Breast cancer 19 | 3,578
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Multiple myeloma 17 | 1,332
Waldenstrons macroglobulinemia 17 | 765
malignant mesothelioma 17 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
ependymoma 15 | 4,679
pancreatic cancer 15 | 2,398
primitive neuroectodermal tumor 15 | 3,035
colon cancer 14 | 1,478
invasive ductal carcinoma 14 | 2,951
pituitary cancer 14 | 1,972
diabetes mellitus 13 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Astrocytoma, Pilocytic 11 | 3,081
Autosomal recessive predisposition 11 | 1,442
cystic fibrosis 11 | 1,696
Muscle hypotonia 10 | 571
acute quadriplegic myopathy 10 | 1,158
lung carcinoma 10 | 2,843
Breast Neoplasms 9 | 445
Cognitive delay 9 | 608
Epilepsy 9 | 792
Global developmental delay 9 | 608
Mammary Neoplasms 9 | 425
Mental and motor retardation 9 | 608
adrenocortical carcinoma 9 | 1,428
astrocytoma 9 | 1,146
ductal carcinoma in situ 9 | 1,745
non primary Sjogren syndrome sicca 9 | 891
pediatric high grade glioma 9 | 1,064
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Kidney cancer 8 | 2,613
Seizures 8 | 596
Stomach Neoplasms 8 | 300
interstitial cystitis 8 | 2,312
oligodendroglioma 8 | 2,850
primary pancreatic ductal adenocarcinoma 8 | 1,109
Intellectual disability 7 | 1,016
group 4 medulloblastoma 7 | 1,855
hepatocellular carcinoma 7 | 547
nasopharyngeal carcinoma 7 | 1,058
Atopic dermatitis 6 | 952
Carcinoma, Hepatocellular 6 | 228
Colorectal Neoplasms 6 | 243
Duchenne muscular dystrophy 6 | 601
Liver carcinoma 6 | 240
Osteoarthritis 6 | 184
Osteoporosis 6 | 363
Schizophrenia 6 | 1,160
Strabismus 6 | 270
Vascular disease 6 | 319
active Crohn's disease 6 | 922
breast carcinoma 6 | 1,638
sonic hedgehog group medulloblastoma 6 | 467
ulcerative colitis 6 | 1,819
Anemia 5 | 365
Carcinoma, Squamous Cell 5 | 110
Colonic Neoplasms 5 | 142
Dull intelligence 5 | 645
Failure to gain weight 5 | 365
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Neurodegenerative disease 5 | 414
Pediatric failure to thrive 5 | 365
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Sensorineural Hearing Loss (disorder) 5 | 284
Small head 5 | 374
Squamous cell carcinoma 5 | 129
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
mucosa-associated lymphoid tissue lymphoma 5 | 484
Bipolar Disorder 4 | 666
Depressive disorder 4 | 409
Endometriosis 4 | 540
Kidney disease 4 | 430
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
gastric carcinoma 4 | 807

Tissue

Digestive Tract 78 | 17,369
Endocrine System 78 | 18,159
Liver and Pancreas 78 | 16,750
Male tissues 78 | 17,142
Nervous System 78 | 16,725
Skin and soft tissues 78 | 17,230
Blood and immune system 77 | 16,909
Female tissues 77 | 17,400
Urinary Tract 77 | 16,678
Respiratory system 76 | 16,393
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 48 | 12,091
Enzyme 21 | 4,145
Transcription Factor 4 | 1,400
Transporter 4 | 473
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Colonic adenocarcinoma cell 81 | 81
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.61683 3311.4 251
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.95809 83.3 241
Small ubiquitin-related modifier 1 SUMO1 Tbio Non-IDG -2.72599 482.7 786
Kelch-like protein 18 KLHL18 Tdark Non-IDG 0.19 0.56 37
Ferritin heavy chain FTH1 Tbio Non-IDG -3.00480 982.1 562
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.68189 4548.4 1886
NADPH oxidase activator 1 NOXA1 Tbio Enzyme -1.24428 16.9 95
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393