Development Level

Tbio 95 | 10,625
Tdark 34 | 7,003
Tchem 21 | 1,890
Tclin 9 | 602

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible non-olfactory GPCR Proteins 3 | 143

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 5 | 226
embryonic lethality prior to o... 5 | 148
preweaning lethality, incomple... 5 | 260
decreased body weight 3 | 174
embryonic lethality prior to t... 3 | 187
abnormal seminal vesicle morph... 2 | 47
decreased grip strength 2 | 123
decreased leukocyte cell numbe... 2 | 54
decreased vertical activity 2 | 22
hyperactivity 2 | 108
hypoactivity 2 | 89
increased body weight 2 | 42
increased grip strength 2 | 83
increased or absent threshold ... 2 | 128
short tibia 2 | 82
straub tail 2 | 26
abnormal QRS complex 1 | 25
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
enlarged heart 1 | 111
improved glucose tolerance 1 | 56
increased IgA level 1 | 1
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating glycerol... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased exploration in new e... 1 | 56
increased mean corpuscular vol... 1 | 91
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

medulloblastoma, large-cell 84 | 6,234
ovarian cancer 82 | 8,484
glioblastoma 65 | 5,572
atypical teratoid / rhabdoid tumor 60 | 4,369
psoriasis 54 | 6,685
oligodendroglioma 49 | 2,849
osteosarcoma 47 | 7,933
primitive neuroectodermal tumor 47 | 3,031
pilocytic astrocytoma 44 | 3,086
pediatric high grade glioma 38 | 2,712
Pick disease 37 | 1,893
ependymoma 37 | 2,514
astrocytic glioma 34 | 2,241
Breast cancer 33 | 3,094
lung cancer 33 | 4,466
subependymal giant cell astrocytoma 32 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,956
invasive ductal carcinoma 28 | 2,950
lung carcinoma 27 | 2,844
adult high grade glioma 26 | 2,148
pituitary cancer 26 | 1,972
malignant mesothelioma 24 | 3,162
astrocytoma 23 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
interstitial cystitis 22 | 2,299
non-small cell lung cancer 22 | 2,798
posterior fossa group B ependymoma 22 | 1,530
group 3 medulloblastoma 21 | 2,254
lung adenocarcinoma 21 | 2,713
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Carcinoma 19 | 2,147
cystic fibrosis 19 | 1,665
medulloblastoma 19 | 1,524
Multiple myeloma 18 | 1,327
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 18 | 1,875
sonic hedgehog group medulloblastoma 18 | 1,482
breast carcinoma 17 | 1,614
ulcerative colitis 17 | 2,087
Epilepsy 16 | 346
posterior fossa group A ependymoma 16 | 1,511
colon cancer 15 | 1,475
pancreatic cancer 15 | 2,300
dermatomyositis 14 | 933
Cancer 13 | 2,346
progressive supranuclear palsy 13 | 674
atypical teratoid/rhabdoid tumor 12 | 1,095
spina bifida 12 | 1,064
Alzheimer's disease 11 | 644
diabetes mellitus 11 | 1,663
tuberculosis 11 | 1,557
Down syndrome 10 | 548
Rheumatoid Arthritis 10 | 1,160
acute myeloid leukemia 10 | 780
adrenocortical carcinoma 10 | 1,427
aldosterone-producing adenoma 9 | 664
non primary Sjogren syndrome sicca 9 | 840
Atopic dermatitis 8 | 944
Neurodegenerative disease 8 | 383
Parkinson's disease 8 | 364
Schizophrenia 8 | 501
Toxic encephalopathy 8 | 131
acute quadriplegic myopathy 8 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
cutaneous lupus erythematosus 8 | 1,056
fibroadenoma 8 | 557
Multiple Sclerosis 7 | 498
active Crohn's disease 7 | 918
gastric cancer 7 | 430
gastric carcinoma 7 | 832
juvenile dermatomyositis 7 | 1,189
nasopharyngeal carcinoma 7 | 1,056
primary pancreatic ductal adenocarcinoma 7 | 1,271
Autistic Disorder 6 | 320
Endometriosis 6 | 535
Polycystic Ovary Syndrome 6 | 332
chronic rhinosinusitis 6 | 512
Amyotrophic Lateral Sclerosis 5 | 431
Intellectual disability 5 | 573
Vascular disease 5 | 281
pancreatic carcinoma 5 | 567
primary Sjogren syndrome 5 | 789
urothelial carcinoma 5 | 318
Cerebrovascular disease 4 | 231
Crohn's disease 4 | 304
Dementia 4 | 129
Duchenne muscular dystrophy 4 | 602
Eaton-Lambert syndrome 4 | 40
Hypertension 4 | 287
IGA Glomerulonephritis 4 | 454
Kidney disease 4 | 396
Obesity 4 | 616
active ulcerative colitis 4 | 477
esophageal adenocarcinoma 4 | 737
facioscapulohumeral dystrophy 4 | 286
nephrosclerosis 4 | 329
severe Alzheimer's disease 4 | 49
Prostatic Neoplasms 3 | 471
periodontitis 3 | 269

Tissue

Nervous System 156 | 18,561
Urinary Tract 156 | 18,444
Digestive Tract 155 | 18,473
Endocrine System 155 | 18,512
Female tissues 155 | 18,647
Liver and Pancreas 155 | 18,136
Blood and immune system 154 | 17,995
Cardiovascular System 154 | 17,958
Skin and soft tissues 153 | 18,115
Male tissues 151 | 17,969
Respiratory system 150 | 17,484

Target Family

Non-IDG 77 | 11,971
Enzyme 40 | 4,146
Transporter 12 | 473
Ion Channel 11 | 341
GPCR 7 | 406
Transcription Factor 7 | 1,400
oGPCR 3 | 421
Kinase 1 | 634
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Cerebral cortex 159 | 159
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Monocarboxylate transporter 14 SLC16A14 Tdark Transporter -0.69265 4.88 34
Putative GRINL1B complex locus protein 2 GCOM2 Tdark Non-IDG -1.14190 15.0 0
LIM/homeobox protein Lhx2 LHX2 Tbio Transcription Factor -1.89097 87.7 161
Signal recognition particle 9 kDa protein SRP9 Tbio Non-IDG -1.49375 30.2 29
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
Choline transporter-like protein 2 SLC44A2 Tbio Transporter -1.57202 38.4 77
Olfactory receptor 13A1 OR13A1 Tdark oGPCR 0.00000 2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase PCMT1 Tbio Enzyme -1.78815 65.1 138
ADM ADM Tchem Non-IDG -3.25380 1832.5 293
5-formyltetrahydrofolate cyclo-ligase MTHFS Tbio Enzyme -1.10551 12.8 142