Development Level

Tbio 104 | 11,651
Tdark 30 | 6,593
Tchem 15 | 1,388
Tclin 10 | 612

Collection

RFA-RM-18-021 5 | 328
GPCR: IDG Consortium (Targets) 3 | 126
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 9 | 499
embryonic lethality prior to o... 7 | 239
abnormal behavior 6 | 298
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
embryonic growth retardation 4 | 106
hyperactivity 4 | 148
decreased body weight 3 | 161
abnormal behavioral response t... 2 | 66
abnormal seminal vesicle morph... 2 | 114
decreased circulating bilirubi... 2 | 19
decreased leukocyte cell numbe... 2 | 73
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased bone mineral content 2 | 108
increased lean body mass 2 | 172
increased startle reflex 2 | 112
abnormal QT variability 1 | 10
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal placenta morphology 1 | 5
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
decreased B cell number 1 | 5
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hydrometra 1 | 53
increased IgA level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
long tibia 1 | 25
premature death 1 | 5
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 94 | 11,493
medulloblastoma, large-cell 84 | 6,241
ovarian cancer 82 | 8,520
atypical teratoid / rhabdoid tumor 71 | 5,112
glioblastoma 67 | 5,792
ependymoma 65 | 4,679
psoriasis 55 | 6,694
adult high grade glioma 50 | 3,801
group 3 medulloblastoma 50 | 4,104
oligodendroglioma 50 | 2,850
osteosarcoma 48 | 7,950
primitive neuroectodermal tumor 47 | 3,035
Astrocytoma, Pilocytic 46 | 3,081
astrocytic glioma 44 | 2,597
Pick disease 37 | 1,894
lung cancer 36 | 4,740
Breast cancer 34 | 3,578
subependymal giant cell astrocytoma 32 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
invasive ductal carcinoma 28 | 2,951
lung carcinoma 27 | 2,843
pituitary cancer 26 | 1,972
non-small cell lung cancer 25 | 2,890
malignant mesothelioma 24 | 3,232
Epilepsy 23 | 792
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
Kidney cancer 22 | 2,613
Schizophrenia 22 | 1,160
interstitial cystitis 22 | 2,312
lung adenocarcinoma 22 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
cystic fibrosis 19 | 1,696
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 18 | 1,855
Multiple myeloma 17 | 1,332
breast carcinoma 17 | 1,638
pancreatic cancer 16 | 2,398
colon cancer 15 | 1,478
dermatomyositis 15 | 966
Cancer 14 | 2,499
pediatric high grade glioma 14 | 1,064
Autosomal recessive predisposition 13 | 1,442
Bipolar Disorder 13 | 666
astrocytoma 13 | 1,146
progressive supranuclear palsy 13 | 676
tuberculosis 13 | 2,010
Alzheimer's disease 12 | 658
Intellectual disability 12 | 1,016
spina bifida 12 | 1,074
ulcerative colitis 12 | 1,819
Seizures 11 | 596
diabetes mellitus 11 | 1,728
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Neurodegenerative disease 10 | 414
Parkinson's disease 10 | 392
Poor school performance 10 | 645
Rheumatoid arthritis 10 | 1,191
acute myeloid leukemia 10 | 783
adrenocortical carcinoma 10 | 1,428
Alcoholic Intoxication, Chronic 9 | 289
Cognitive delay 9 | 608
Down syndrome 9 | 499
Global developmental delay 9 | 608
Mental and motor retardation 9 | 608
active ulcerative colitis 9 | 764
aldosterone-producing adenoma 9 | 665
non primary Sjogren syndrome sicca 9 | 891
Atopic dermatitis 8 | 952
Liver Cirrhosis, Experimental 8 | 769
Toxic encephalopathy 8 | 141
acute quadriplegic myopathy 8 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
fibroadenoma 8 | 559
gastric cancer 8 | 459
Depressive disorder 7 | 409
Mental Depression 7 | 333
Multiple Sclerosis 7 | 540
Muscle hypotonia 7 | 571
active Crohn's disease 7 | 922
juvenile dermatomyositis 7 | 1,187
nasopharyngeal carcinoma 7 | 1,058
primary pancreatic ductal adenocarcinoma 7 | 1,109
Amyotrophic lateral sclerosis 6 | 451
Autistic Disorder 6 | 364
Cerebellar Ataxia 6 | 304
Dementia 6 | 175
Endometriosis 6 | 540
Myoclonus 6 | 74
Polycystic ovary syndrome 6 | 360
chronic rhinosinusitis 6 | 512
gastric carcinoma 6 | 807
posterior fossa group A ependymoma 6 | 468
Crohn's disease 5 | 321
Vascular disease 5 | 319
primary Sjogren syndrome 5 | 735

Tissue

Endocrine System 151 | 18,159
Nervous System 151 | 16,725
Digestive Tract 148 | 17,369
Female tissues 147 | 17,400
Skin and soft tissues 145 | 17,230
Urinary Tract 144 | 16,678
Blood and immune system 143 | 16,909
Male tissues 142 | 17,142
Liver and Pancreas 139 | 16,750
Respiratory system 136 | 16,393
Cardiovascular System 131 | 15,192

Target Family

Non-IDG 77 | 12,091
Enzyme 40 | 4,145
Transporter 12 | 473
Ion Channel 11 | 344
GPCR 7 | 408
Transcription Factor 7 | 1,400
oGPCR 3 | 421
Kinase 1 | 634
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Cerebral cortex 159 | 159
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
IQ and AAA domain-containing protein 1 IQCA1 Tbio Non-IDG -0.80618 5.26 77
Gap junction beta-6 protein GJB6 Tbio Non-IDG -2.99235 908.9 170
TSC22 domain family protein 1 TSC22D1 Tbio Transcription Factor -1.54599 46.0 300
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H PIGH Tbio Enzyme -1.19063 13.0 116
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Sorting nexin-32 SNX32 Tdark Non-IDG 0.35 0.28 89
Nuclear receptor corepressor 2 NCOR2 Tchem Transcription Factor -2.83392 645.1 189
Mediator of RNA polymerase II transcription subunit 21 MED21 Tbio Enzyme -1.12786 14.4 113
Protein canopy homolog 3 CNPY3 Tbio Non-IDG -0.70014 5.05 115
NCK-interacting protein with SH3 domain NCKIPSD Tbio Non-IDG -1.01986 16.6 99