Development Level

Tbio 76 | 11,445
Tdark 22 | 6,588
Tchem 9 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 4 | 298
abnormal coat-hair pigmentatio... 3 | 64
abnormal gait 3 | 69
enlarged heart 3 | 210
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal head size 2 | 6
abnormal heart morphology 2 | 162
abnormal iris morphology 2 | 13
abnormal pelvic girdle bone mo... 2 | 12
abnormal placement of pupils 2 | 6
abnormal retinal blood vessel ... 2 | 26
abnormal snout morphology 2 | 23
decreased bone mineral content 2 | 151
decreased fasted circulating g... 2 | 65
decreased total body fat amoun... 2 | 207
improved glucose tolerance 2 | 79
increased erythrocyte cell num... 2 | 39
increased hematocrit 2 | 46
mammalian phenotype 2 | 17
narrow eye opening 2 | 12
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal response to new envir... 1 | 10
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
head bobbing 1 | 5
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
male infertility 1 | 123
mydriasis 1 | 6
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small liver 1 | 8
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 65 | 11,493
ovarian cancer 50 | 8,520
medulloblastoma, large-cell 46 | 6,241
atypical teratoid / rhabdoid tumor 43 | 5,112
glioblastoma 41 | 5,792
osteosarcoma 38 | 7,950
psoriasis 37 | 6,694
ependymoma 34 | 4,679
group 3 medulloblastoma 33 | 4,104
adult high grade glioma 32 | 3,801
oligodendroglioma 31 | 2,850
Astrocytoma, Pilocytic 30 | 3,081
astrocytic glioma 28 | 2,597
lung cancer 27 | 4,740
primitive neuroectodermal tumor 24 | 3,035
lung carcinoma 22 | 2,843
Pick disease 21 | 1,894
malignant mesothelioma 21 | 3,232
subependymal giant cell astrocytoma 21 | 2,287
group 4 medulloblastoma 17 | 1,855
interstitial cystitis 17 | 2,312
lung adenocarcinoma 17 | 2,716
Breast cancer 15 | 3,578
Cancer 14 | 2,499
Multiple myeloma 14 | 1,332
non-small cell lung cancer 14 | 2,890
pancreatic cancer 14 | 2,398
pituitary cancer 14 | 1,972
invasive ductal carcinoma 13 | 2,951
tuberculosis 13 | 2,010
Epilepsy 12 | 792
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Autosomal recessive predisposition 11 | 1,442
Schizophrenia 11 | 1,160
colon cancer 11 | 1,478
cystic fibrosis 11 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Alzheimer's disease 9 | 658
Kidney cancer 9 | 2,613
Rheumatoid arthritis 9 | 1,191
cutaneous lupus erythematosus 9 | 1,057
Intellectual disability 8 | 1,016
Seizures 8 | 596
adrenocortical carcinoma 8 | 1,428
pediatric high grade glioma 8 | 1,064
Down syndrome 7 | 499
Dull intelligence 7 | 645
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
active ulcerative colitis 7 | 764
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
posterior fossa group B ependymoma 7 | 416
ulcerative colitis 7 | 1,819
Liver Cirrhosis, Experimental 6 | 769
Muscle hypotonia 6 | 571
active Crohn's disease 6 | 922
chronic rhinosinusitis 6 | 512
non primary Sjogren syndrome sicca 6 | 891
primary pancreatic ductal adenocarcinoma 6 | 1,109
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074
Bipolar Disorder 5 | 666
Cerebral atrophy 5 | 178
Electroencephalogram abnormal 5 | 101
Hyperreflexia 5 | 209
Muscle Spasticity 5 | 195
Neurodegenerative disease 5 | 414
Retinitis Pigmentosa 5 | 226
acute quadriplegic myopathy 5 | 1,158
pancreatic carcinoma 5 | 562
primary Sjogren syndrome 5 | 735
Amyotrophic lateral sclerosis 4 | 451
Anteverted nostril 4 | 191
Atrophy of cerebellum 4 | 103
Cerebellar degeneration 4 | 103
Crohn's disease 4 | 321
Depressive disorder 4 | 409
Dysarthria 4 | 192
Dystonia 4 | 164
Endometriosis 4 | 540
Growth delay 4 | 114
Growth failure 4 | 114
Growth retardation 4 | 115
Infratentorial atrophy 4 | 103
Poor growth 4 | 114
Waldenstrons macroglobulinemia 4 | 765
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
hereditary spastic paraplegia 4 | 318
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 107 | 18,159
Nervous System 106 | 16,725
Skin and soft tissues 105 | 17,230
Digestive Tract 104 | 17,369
Female tissues 104 | 17,400
Male tissues 104 | 17,142
Blood and immune system 102 | 16,909
Respiratory system 102 | 16,393
Urinary Tract 102 | 16,678
Liver and Pancreas 101 | 16,750
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 28 | 4,145
Transcription Factor 6 | 1,400
Transporter 5 | 473
Ion Channel 3 | 344
Kinase 2 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Caudate nucleus 109 | 109
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
Rho guanine nucleotide exchange factor 33 ARHGEF33 Tdark Non-IDG 1.00 0.05 51
Multiple myeloma tumor-associated protein 2 C1orf35 Tdark Non-IDG 0.00000 1.00 39
Thioredoxin domain-containing protein 6 NME9 Tbio Non-IDG -0.15719 1.86 110
Butyrophilin subfamily 2 member A2 BTN2A2 Tdark Non-IDG -0.21927 2.32 84
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
Glycerophosphoinositol inositolphosphodiesterase GDPD2 GDPD2 Tbio Enzyme -0.91821 8.09 101
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89