Development Level

Tbio 137 | 10,625
Tchem 32 | 1,890
Tdark 22 | 7,003
Tclin 7 | 602

IMPC Phenotype

preweaning lethality, complete... 9 | 633
increased mean corpuscular vol... 6 | 91
increased mean corpuscular hem... 5 | 93
abnormal behavior 4 | 226
decreased circulating alanine ... 4 | 53
decreased total body fat amoun... 4 | 186
increased circulating alkaline... 4 | 119
abnormal lens morphology 3 | 73
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
decreased leukocyte cell numbe... 3 | 54
embryonic lethality prior to t... 3 | 187
thrombocytopenia 3 | 46
abnormal coat-hair pigmentatio... 2 | 54
abnormal embryo size 2 | 112
abnormal retina morphology 2 | 100
decreased grip strength 2 | 123
decreased mean corpuscular hem... 2 | 34
decreased startle reflex 2 | 48
decreased threshold for audito... 2 | 32
embryonic lethality prior to o... 2 | 148
hyperactivity 2 | 108
increased body weight 2 | 42
increased circulating iron lev... 2 | 25
increased circulating potassiu... 2 | 31
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased lean body mass 2 | 107
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
tremors 2 | 34
abnormal coat- hair morphology 1 | 18
abnormal craniofacial morpholo... 1 | 12
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tail bud morphology 1 | 6
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased CD8-positive, alpha-... 1 | 26
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
embryonic growth retardation 1 | 28
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
lethargy 1 | 5
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
small seminal vesicle 1 | 6
small testis 1 | 37

Disease

ovarian cancer 118 | 8,491
osteosarcoma 106 | 7,933
psoriasis 94 | 6,685
glioblastoma 75 | 5,572
lung cancer 74 | 4,473
medulloblastoma, large-cell 72 | 6,234
atypical teratoid / rhabdoid tumor 56 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
Breast cancer 46 | 3,098
malignant mesothelioma 45 | 3,163
pancreatic cancer 44 | 2,300
non-small cell lung cancer 43 | 2,798
invasive ductal carcinoma 42 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,988
Cancer 40 | 2,346
ulcerative colitis 40 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
lung adenocarcinoma 38 | 2,714
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,795
primitive neuroectodermal tumor 37 | 3,031
pilocytic astrocytoma 32 | 3,086
cystic fibrosis 31 | 1,670
oligodendroglioma 30 | 2,849
pediatric high grade glioma 29 | 2,712
astrocytoma 28 | 1,493
diabetes mellitus 28 | 1,663
Multiple myeloma 27 | 1,327
breast carcinoma 27 | 1,614
ependymoma 27 | 2,514
interstitial cystitis 27 | 2,299
tuberculosis 27 | 1,563
adult high grade glioma 26 | 2,148
ductal carcinoma in situ 26 | 1,745
lung carcinoma 26 | 2,844
Pick disease 24 | 1,893
medulloblastoma 24 | 1,524
Carcinoma 23 | 2,147
adrenocortical carcinoma 23 | 1,427
pituitary cancer 23 | 1,972
primary pancreatic ductal adenocarcinoma 23 | 1,271
group 3 medulloblastoma 22 | 2,254
colon cancer 21 | 1,475
subependymal giant cell astrocytoma 20 | 2,287
Rheumatoid Arthritis 19 | 1,170
juvenile dermatomyositis 19 | 1,189
acute quadriplegic myopathy 18 | 1,157
dermatomyositis 18 | 966
Atopic dermatitis 17 | 944
astrocytic glioma 17 | 2,241
cutaneous lupus erythematosus 17 | 1,056
active Crohn's disease 16 | 918
group 4 medulloblastoma 16 | 1,875
hepatocellular carcinoma 16 | 550
sonic hedgehog group medulloblastoma 16 | 1,482
spina bifida 16 | 1,064
Obesity 15 | 616
atypical teratoid/rhabdoid tumor 15 | 1,095
tuberculosis and treatment for 6 months 15 | 686
Anemia 14 | 252
primary Sjogren syndrome 14 | 788
Waldenstrons macroglobulinemia 13 | 764
esophageal adenocarcinoma 13 | 737
pancreatic carcinoma 13 | 567
posterior fossa group A ependymoma 13 | 1,511
Duchenne muscular dystrophy 12 | 602
Kidney disease 12 | 397
acute myeloid leukemia 12 | 785
gastric cancer 12 | 436
nasopharyngeal carcinoma 12 | 1,056
progressive supranuclear palsy 12 | 674
Alzheimer's disease 11 | 644
IGA Glomerulonephritis 11 | 454
Prostatic Neoplasms 11 | 471
gastric carcinoma 11 | 832
mucosa-associated lymphoid tissue lymphoma 11 | 480
Atherosclerosis 10 | 275
Endometriosis 10 | 535
chronic rhinosinusitis 10 | 512
fibroadenoma 10 | 557
Amyotrophic Lateral Sclerosis 9 | 432
Down syndrome 9 | 548
Hyperglycemia 9 | 120
Intellectual disability 9 | 573
Liver disease 9 | 219
aldosterone-producing adenoma 9 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
non primary Sjogren syndrome sicca 9 | 840
posterior fossa group B ependymoma 9 | 1,530
Cerebrovascular disease 8 | 231
Coronary artery disease 8 | 240
Liver carcinoma 8 | 217
nephrosclerosis 8 | 329
Drug-Induced Liver Injury 7 | 118
Hypertension 7 | 293
Lung Neoplasms 7 | 171
Mammary Neoplasms, Experimental 7 | 149
Melanoma 7 | 261
Metabolic syndrome X 7 | 155
inflammatory breast cancer 7 | 404
Schizophrenia 6 | 503

Tissue

Cardiovascular System 196 | 17,957
Female tissues 196 | 18,646
Liver and Pancreas 196 | 18,135
Nervous System 196 | 18,560
Digestive Tract 195 | 18,472
Endocrine System 195 | 18,511
Skin and soft tissues 195 | 18,114
Urinary Tract 195 | 18,443
Male tissues 194 | 17,968
Blood and immune system 192 | 17,994
Respiratory system 192 | 17,483

Target Family

Non-IDG 114 | 11,969
Enzyme 59 | 4,146
Kinase 11 | 634
Transcription Factor 6 | 1,400
Transporter 6 | 473
Epigenetic 1 | 242
GPCR 1 | 408

Jensen-KB Tissue

CL-48 cell 198 | 198
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.03044 1092.0 356
Protein phosphatase methylesterase 1 PPME1 Tchem Enzyme -1.49604 33.2 153
Pregnancy-specific beta-1-glycoprotein 4 PSG4 Tbio Non-IDG -0.81013 9.85 60
Pregnancy-specific beta-1-glycoprotein 9 PSG9 Tbio Non-IDG -1.57508 37.9 145
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Prominin-1 PROM1 Tbio Non-IDG -3.27144 1922.5 226
ATP synthase mitochondrial F1 complex assembly factor 1 ATPAF1 Tdark Enzyme -1.23749 17.2 39
Electron transfer flavoprotein subunit beta ETFB Tbio Non-IDG -1.40937 19.3 166
Sacsin SACS Tbio Non-IDG -2.60343 385.2 9
Platelet-activating factor receptor PTAFR Tchem GPCR -1.98455 106.0 120