Development Level

Tbio 151 | 11,651
Tchem 24 | 1,388
Tdark 18 | 6,593
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
embryonic lethality prior to t... 4 | 278
increased circulating alkaline... 4 | 122
increased mean corpuscular vol... 4 | 92
increased startle reflex 4 | 112
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
decreased circulating alanine ... 3 | 47
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
hyperactivity 3 | 148
increased hematocrit 3 | 46
increased or absent threshold ... 3 | 101
thrombocytopenia 3 | 56
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo turning 2 | 31
abnormal epididymis morphology 2 | 42
abnormal locomotor behavior 2 | 24
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating aspartat... 2 | 34
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged epididymis 2 | 31
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating alanine ... 2 | 13
increased circulating iron lev... 2 | 30
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased neutrophil cell numb... 2 | 46
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
tremors 2 | 39
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
corneal opacity 1 | 32
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
hypoactivity 1 | 132
impaired righting response 1 | 26
increased aggression 1 | 4
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
small superior vagus ganglion 1 | 74
trunk curl 1 | 16

Disease

Carcinoma 127 | 11,493
ovarian cancer 118 | 8,520
osteosarcoma 107 | 7,950
psoriasis 94 | 6,694
glioblastoma 77 | 5,792
lung cancer 76 | 4,740
medulloblastoma, large-cell 72 | 6,241
atypical teratoid / rhabdoid tumor 65 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,291
Breast cancer 52 | 3,578
malignant mesothelioma 49 | 3,232
pancreatic cancer 45 | 2,398
ependymoma 43 | 4,679
non-small cell lung cancer 43 | 2,890
Cancer 42 | 2,499
invasive ductal carcinoma 42 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,962
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,989
adult high grade glioma 40 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
lung adenocarcinoma 38 | 2,716
primitive neuroectodermal tumor 37 | 3,035
group 3 medulloblastoma 35 | 4,104
Astrocytoma, Pilocytic 33 | 3,081
tuberculosis 32 | 2,010
cystic fibrosis 31 | 1,696
ulcerative colitis 31 | 1,819
diabetes mellitus 30 | 1,728
oligodendroglioma 30 | 2,850
Autosomal recessive predisposition 28 | 1,442
breast carcinoma 28 | 1,638
Multiple myeloma 27 | 1,332
interstitial cystitis 27 | 2,312
ductal carcinoma in situ 26 | 1,745
lung carcinoma 26 | 2,843
group 4 medulloblastoma 25 | 1,855
Kidney cancer 24 | 2,613
Pick disease 24 | 1,894
adrenocortical carcinoma 23 | 1,428
astrocytic glioma 23 | 2,597
pituitary cancer 23 | 1,972
astrocytoma 22 | 1,146
colon cancer 22 | 1,478
primary pancreatic ductal adenocarcinoma 20 | 1,109
subependymal giant cell astrocytoma 20 | 2,287
Rheumatoid arthritis 19 | 1,191
juvenile dermatomyositis 19 | 1,187
Anemia 18 | 365
Liver Cirrhosis, Experimental 18 | 769
Obesity 18 | 678
acute quadriplegic myopathy 18 | 1,158
dermatomyositis 18 | 966
Atopic dermatitis 17 | 952
Schizophrenia 17 | 1,160
cutaneous lupus erythematosus 17 | 1,057
Intellectual disability 16 | 1,016
active Crohn's disease 16 | 922
active ulcerative colitis 16 | 764
spina bifida 16 | 1,074
hepatocellular carcinoma 15 | 547
pediatric high grade glioma 15 | 1,064
primary Sjogren syndrome 14 | 735
Waldenstrons macroglobulinemia 13 | 765
esophageal adenocarcinoma 13 | 737
gastric cancer 13 | 459
pancreatic carcinoma 13 | 562
Duchenne muscular dystrophy 12 | 601
Epilepsy 12 | 792
Muscle hypotonia 12 | 571
acute myeloid leukemia 12 | 783
medulloblastoma 12 | 720
mucosa-associated lymphoid tissue lymphoma 12 | 484
nasopharyngeal carcinoma 12 | 1,058
progressive supranuclear palsy 12 | 676
Alzheimer's disease 11 | 658
Bipolar Disorder 11 | 666
Dull intelligence 11 | 645
Kidney disease 11 | 430
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Prostatic Neoplasms 11 | 495
tuberculosis and treatment for 6 months 11 | 409
Atherosclerosis 10 | 291
Endometriosis 10 | 540
Liver disease 10 | 237
Lung Neoplasms 10 | 232
Melanoma 10 | 711
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
chronic rhinosinusitis 10 | 512
fibroadenoma 10 | 559
gastric carcinoma 10 | 807
non primary Sjogren syndrome sicca 10 | 891
Cognitive delay 9 | 608
Global developmental delay 9 | 608
Hepatomegaly 9 | 285
Mental and motor retardation 9 | 608
aldosterone-producing adenoma 9 | 665
nephrosclerosis 9 | 333

Tissue

Digestive Tract 194 | 17,369
Endocrine System 194 | 18,159
Male tissues 194 | 17,142
Skin and soft tissues 194 | 17,230
Blood and immune system 193 | 16,909
Female tissues 193 | 17,400
Liver and Pancreas 192 | 16,750
Urinary Tract 192 | 16,678
Respiratory system 188 | 16,393
Nervous System 185 | 16,725
Cardiovascular System 181 | 15,192

Target Family

Non-IDG 115 | 12,091
Enzyme 60 | 4,145
Kinase 11 | 634
Transcription Factor 6 | 1,400
Transporter 6 | 473
Epigenetic 1 | 242
GPCR 1 | 408

Jensen-KB Tissue

CL-48 cell 200 | 200
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein arginine methyltransferase NDUFAF7, mitochondrial NDUFAF7 Tbio Enzyme -0.45102 2.70 64
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Glycerol kinase 3 GK3P Tdark Kinase -1.84692 109.0 0
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
Protein Z-dependent protease inhibitor SERPINA10 Tbio Enzyme -1.87106 72.9 218
Choline/ethanolaminephosphotransferase 1 CEPT1 Tbio Enzyme -1.65915 46.8 82
Serine/threonine-protein kinase VRK1 VRK1 Tbio Kinase -2.05267 119.8 168
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Tubulin monoglycylase TTLL3 TTLL3 Tbio Enzyme -0.53902 4.01 18
Nuclear receptor corepressor 2 NCOR2 Tchem Transcription Factor -2.83392 645.1 189