Development Level

Tbio 154 | 11,445
Tchem 34 | 1,598
Tclin 17 | 613
Tdark 16 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to o... 7 | 239
increased lean body mass 6 | 172
decreased total body fat amoun... 5 | 207
abnormal heart morphology 4 | 162
increased bone mineral content 4 | 108
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased circulating HDL chol... 3 | 80
increased hematocrit 3 | 46
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal epididymis morphology 2 | 42
abnormal pericardium morpholog... 2 | 26
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
increased circulating choleste... 2 | 66
male infertility 2 | 123
thrombocytosis 2 | 27
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
corneal opacity 1 | 32
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating potassiu... 1 | 29
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened RR interval 1 | 17
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 156 | 11,493
ovarian cancer 133 | 8,520
osteosarcoma 101 | 7,950
lung cancer 92 | 4,740
psoriasis 89 | 6,694
Cancer 85 | 2,499
glioblastoma 75 | 5,792
medulloblastoma, large-cell 75 | 6,241
Breast cancer 65 | 3,578
atypical teratoid / rhabdoid tumor 57 | 5,112
ependymoma 56 | 4,679
malignant mesothelioma 55 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,291
group 3 medulloblastoma 49 | 4,104
invasive ductal carcinoma 46 | 2,951
lung adenocarcinoma 45 | 2,716
adult high grade glioma 42 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,955
oligodendroglioma 42 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
non-small cell lung cancer 40 | 2,890
pancreatic cancer 40 | 2,398
primitive neuroectodermal tumor 36 | 3,035
Kidney cancer 35 | 2,613
Multiple myeloma 35 | 1,332
diabetes mellitus 35 | 1,728
Astrocytoma, Pilocytic 34 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 33 | 1,962
astrocytic glioma 32 | 2,597
lung carcinoma 29 | 2,843
tuberculosis 28 | 2,010
ductal carcinoma in situ 27 | 1,745
group 4 medulloblastoma 27 | 1,855
subependymal giant cell astrocytoma 27 | 2,287
acute quadriplegic myopathy 26 | 1,158
breast carcinoma 25 | 1,638
colon cancer 25 | 1,478
cystic fibrosis 25 | 1,696
astrocytoma 24 | 1,146
interstitial cystitis 23 | 2,312
Breast Neoplasms 22 | 445
Autosomal recessive predisposition 21 | 1,442
Mammary Neoplasms 21 | 425
Pick disease 21 | 1,894
pediatric high grade glioma 21 | 1,064
pituitary cancer 21 | 1,972
adrenocortical carcinoma 20 | 1,428
dermatomyositis 20 | 966
Waldenstrons macroglobulinemia 19 | 765
ulcerative colitis 19 | 1,819
Stomach Neoplasms 18 | 300
active Crohn's disease 18 | 922
juvenile dermatomyositis 17 | 1,187
nasopharyngeal carcinoma 17 | 1,058
Endometriosis 16 | 540
Prostatic Neoplasms 16 | 495
Rheumatoid arthritis 16 | 1,191
non primary Sjogren syndrome sicca 16 | 891
primary pancreatic ductal adenocarcinoma 16 | 1,109
Atopic dermatitis 15 | 952
Liver Cirrhosis, Experimental 15 | 769
Alzheimer's disease 14 | 658
Mammary Neoplasms, Experimental 14 | 154
Schizophrenia 14 | 1,160
cutaneous lupus erythematosus 14 | 1,057
fibroadenoma 14 | 559
Duchenne muscular dystrophy 13 | 601
esophageal adenocarcinoma 13 | 737
Neurodegenerative disease 12 | 414
Obesity 12 | 678
spina bifida 12 | 1,074
Adenocarcinoma 11 | 122
Bipolar Disorder 11 | 666
Cognitive delay 11 | 608
Epilepsy 11 | 792
Global developmental delay 11 | 608
Intellectual disability 11 | 1,016
Lung Neoplasms 11 | 232
Mental and motor retardation 11 | 608
Animal Mammary Neoplasms 10 | 136
Disease Models, Animal 10 | 155
Down syndrome 10 | 499
Mammary Neoplasms, Animal 10 | 136
Neoplasm Invasiveness 10 | 161
Polycystic ovary syndrome 10 | 360
Renal Cell Carcinoma 10 | 214
Vascular disease 10 | 319
active ulcerative colitis 10 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
gastric carcinoma 10 | 807
Adenocarcinoma of lung 9 | 142
Carcinoma, Hepatocellular 9 | 228
Liver carcinoma 9 | 240
Muscle hypotonia 9 | 571
Seizures 9 | 596
Short stature 9 | 531
pancreatic carcinoma 9 | 562
Kidney disease 8 | 430
primary Sjogren syndrome 8 | 735
progressive supranuclear palsy 8 | 676

Tissue

Endocrine System 219 | 18,159
Male tissues 219 | 17,142
Digestive Tract 218 | 17,369
Female tissues 218 | 17,400
Skin and soft tissues 218 | 17,230
Respiratory system 217 | 16,393
Urinary Tract 217 | 16,678
Blood and immune system 216 | 16,909
Liver and Pancreas 216 | 16,750
Nervous System 214 | 16,725
Cardiovascular System 209 | 15,192

Target Family

Non-IDG 123 | 12,091
Enzyme 52 | 4,145
Kinase 13 | 634
Transcription Factor 11 | 1,400
Epigenetic 6 | 242
Transporter 5 | 473
Nuclear Receptor 4 | 48
TF/Epigenetic 3 | 38
GPCR 2 | 408
Ion Channel 2 | 344

Jensen-KB Tissue

Breast cancer cell 221 | 221
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Inhibitor of growth protein 1 ING1 Tbio Epigenetic -2.05417 130.8 341
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.14287 1343.1 167
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
DEP domain-containing protein 1B DEPDC1B Tbio Non-IDG -0.81968 7.18 94
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299