Development Level

Tbio 142 | 10,625
Tchem 41 | 1,890
Tdark 19 | 7,003
Tclin 17 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
preweaning lethality, complete... 5 | 633
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
decreased body weight 3 | 174
decreased circulating calcium ... 3 | 33
decreased rib number 3 | 59
increased grip strength 3 | 83
increased hematocrit 3 | 36
increased lean body mass 3 | 107
increased total body fat amoun... 3 | 57
abnormal epididymis morphology 2 | 31
abnormal lens morphology 2 | 73
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating creatini... 2 | 31
decreased circulating phosphat... 2 | 15
decreased circulating serum al... 2 | 79
decreased lumbar vertebrae num... 2 | 62
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased heart rate 2 | 17
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
shortened RR interval 2 | 19
abnormal allantois morphology 1 | 3
abnormal bone mineralization 1 | 55
abnormal chorioallantoic fusio... 1 | 2
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal hair growth 1 | 8
abnormal heart left ventricle ... 1 | 20
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal tail bud morphology 1 | 6
abnormal vibrissa morphology 1 | 17
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased respiratory quotient 1 | 12
decreased thoracic vertebrae n... 1 | 7
decreased threshold for audito... 1 | 32
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
enlarged kidney 1 | 7
enlarged lymph nodes 1 | 27
increased B cell number 1 | 23
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased KLRG1-positive NK ce... 1 | 9
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood uric acid leve... 1 | 5
increased body length 1 | 20
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased effector memory CD8-... 1 | 14
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased granulocyte number 1 | 8
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased transitional stage T... 1 | 1
oligodactyly 1 | 14
pale yolk sac 1 | 12
pallor 1 | 13
prolonged PR interval 1 | 4
shortened PR interval 1 | 5
thrombocytosis 1 | 23

Disease

ovarian cancer 132 | 8,484
osteosarcoma 99 | 7,933
psoriasis 89 | 6,685
lung cancer 88 | 4,466
Cancer 80 | 2,346
medulloblastoma, large-cell 75 | 6,234
glioblastoma 71 | 5,572
Breast cancer 56 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 54 | 3,289
malignant mesothelioma 52 | 3,162
atypical teratoid / rhabdoid tumor 45 | 4,369
invasive ductal carcinoma 45 | 2,950
lung adenocarcinoma 45 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
oligodendroglioma 42 | 2,849
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,988
non-small cell lung cancer 40 | 2,798
pancreatic cancer 40 | 2,300
pediatric high grade glioma 38 | 2,712
primitive neuroectodermal tumor 36 | 3,031
Multiple myeloma 35 | 1,327
diabetes mellitus 35 | 1,663
pilocytic astrocytoma 34 | 3,086
ependymoma 33 | 2,514
astrocytoma 31 | 1,493
Carcinoma 30 | 2,147
group 4 medulloblastoma 30 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
lung carcinoma 29 | 2,844
group 3 medulloblastoma 28 | 2,254
subependymal giant cell astrocytoma 27 | 2,287
acute quadriplegic myopathy 26 | 1,157
ductal carcinoma in situ 26 | 1,745
adult high grade glioma 25 | 2,148
colon cancer 25 | 1,475
cystic fibrosis 25 | 1,665
astrocytic glioma 24 | 2,241
breast carcinoma 24 | 1,614
ulcerative colitis 24 | 2,087
interstitial cystitis 22 | 2,299
Mammary Neoplasms 21 | 410
Pick disease 21 | 1,893
pituitary cancer 21 | 1,972
tuberculosis 21 | 1,557
adrenocortical carcinoma 20 | 1,427
dermatomyositis 20 | 933
Waldenstrons macroglobulinemia 19 | 765
primary pancreatic ductal adenocarcinoma 19 | 1,271
Stomach Neoplasms 18 | 282
active Crohn's disease 18 | 918
posterior fossa group A ependymoma 18 | 1,511
sonic hedgehog group medulloblastoma 18 | 1,482
juvenile dermatomyositis 17 | 1,189
nasopharyngeal carcinoma 17 | 1,056
Endometriosis 16 | 535
non primary Sjogren syndrome sicca 16 | 840
Atopic dermatitis 15 | 944
IGA Glomerulonephritis 15 | 454
Prostatic Neoplasms 15 | 471
Rheumatoid Arthritis 15 | 1,160
atypical teratoid/rhabdoid tumor 15 | 1,095
cutaneous lupus erythematosus 14 | 1,056
fibroadenoma 14 | 557
medulloblastoma 14 | 1,524
Duchenne muscular dystrophy 13 | 602
Mammary Neoplasms, Experimental 13 | 150
esophageal adenocarcinoma 13 | 737
Alzheimer's disease 12 | 644
Neurodegenerative disease 12 | 383
Obesity 12 | 616
spina bifida 12 | 1,064
Adenocarcinoma 10 | 115
Animal Mammary Neoplasms 10 | 136
Down syndrome 10 | 548
Renal Cell Carcinoma 10 | 199
Vascular disease 10 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
gastric carcinoma 10 | 832
Liver carcinoma 9 | 217
Peripheral Neuropathy 9 | 303
Polycystic Ovary Syndrome 9 | 332
inflammatory breast cancer 9 | 404
non-small cell lung carcinoma 9 | 413
pancreatic carcinoma 9 | 567
posterior fossa group B ependymoma 9 | 1,530
Amyotrophic Lateral Sclerosis 8 | 431
Disease Progression 8 | 125
Intellectual disability 8 | 573
Lung Neoplasms 8 | 171
hereditary spastic paraplegia 8 | 313
primary Sjogren syndrome 8 | 789
progressive supranuclear palsy 8 | 674
tuberculosis and treatment for 3 months 8 | 327
Adenoma 7 | 165
Kidney disease 7 | 396
Neoplasm Invasiveness 7 | 127
Squamous cell carcinoma of esophagus 7 | 82
acute myeloid leukemia 7 | 780
glioblastoma multiforme 7 | 347
interstitial lung disease 7 | 291

Tissue

Digestive Tract 217 | 18,473
Endocrine System 217 | 18,512
Female tissues 217 | 18,647
Male tissues 217 | 17,969
Nervous System 217 | 18,561
Respiratory system 217 | 17,484
Urinary Tract 217 | 18,444
Blood and immune system 216 | 17,995
Cardiovascular System 216 | 17,958
Liver and Pancreas 216 | 18,136
Skin and soft tissues 216 | 18,115

Target Family

Non-IDG 121 | 11,971
Enzyme 52 | 4,146
Kinase 13 | 634
Transcription Factor 11 | 1,400
Epigenetic 6 | 242
Transporter 5 | 473
Nuclear Receptor 4 | 48
TF/Epigenetic 3 | 38
GPCR 2 | 406
Ion Channel 2 | 341

Jensen-KB Tissue

Breast cancer cell 219 | 219
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Epithelial discoidin domain-containing receptor 1 DDR1 Tchem Kinase -2.21530 0.00000 460
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial COA4 Tbio Enzyme -1.08636 12.3 71
Putative high mobility group protein B1-like 1 HMGB1P1 Tdark Non-IDG -3.17050 1948.8 0
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.32467 28.6 99
Ubiquitin carboxyl-terminal hydrolase 7 USP7 Tchem Enzyme -2.17350 165.7 375
NEDD4-like E3 ubiquitin-protein ligase WWP1 WWP1 Tbio Enzyme -1.57709 42.8 121