Development Level

Tbio 161 | 11,445
Tchem 33 | 1,598
Tdark 13 | 6,588
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 18 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 7 | 298
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
hyperactivity 5 | 148
abnormal embryo size 4 | 220
decreased body weight 4 | 161
abnormal sleep behavior 3 | 70
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased lean body mass 3 | 172
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
short tibia 3 | 97
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating calcium ... 2 | 36
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating creatini... 2 | 38
increased mean corpuscular vol... 2 | 92
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
abnormal allantois morphology 1 | 8
abnormal body wall morphology 1 | 9
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal retinal inner nuclear... 1 | 8
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal vertebrae morphology 1 | 18
absent pinna reflex 1 | 23
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
male infertility 1 | 123
microphthalmia 1 | 26
pallor 1 | 34
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

ovarian cancer 142 | 8,520
Carcinoma 118 | 11,493
lung cancer 95 | 4,740
medulloblastoma, large-cell 90 | 6,241
psoriasis 90 | 6,694
osteosarcoma 84 | 7,950
Cancer 83 | 2,499
glioblastoma 82 | 5,792
atypical teratoid / rhabdoid tumor 74 | 5,112
ependymoma 69 | 4,679
group 3 medulloblastoma 69 | 4,104
Multiple myeloma 67 | 1,332
Breast cancer 55 | 3,578
oligodendroglioma 54 | 2,850
astrocytic glioma 53 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 52 | 2,989
pancreatic cancer 50 | 2,398
adult high grade glioma 49 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
lung adenocarcinoma 46 | 2,716
primitive neuroectodermal tumor 43 | 3,035
invasive ductal carcinoma 42 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,955
Astrocytoma, Pilocytic 40 | 3,081
Pick disease 39 | 1,894
Waldenstrons macroglobulinemia 39 | 765
malignant mesothelioma 39 | 3,232
diabetes mellitus 38 | 1,728
non-small cell lung cancer 38 | 2,890
acute quadriplegic myopathy 36 | 1,158
Schizophrenia 33 | 1,160
lung carcinoma 33 | 2,843
subependymal giant cell astrocytoma 32 | 2,287
Autosomal recessive predisposition 31 | 1,442
primary pancreatic ductal adenocarcinoma 31 | 1,109
breast carcinoma 30 | 1,638
colon cancer 28 | 1,478
Alzheimer's disease 27 | 658
group 4 medulloblastoma 25 | 1,855
juvenile dermatomyositis 25 | 1,187
Amyotrophic lateral sclerosis 24 | 451
Neurodegenerative disease 24 | 414
pituitary cancer 24 | 1,972
tuberculosis 24 | 2,010
cystic fibrosis 23 | 1,696
dermatomyositis 23 | 966
Carcinoma, Hepatocellular 21 | 228
Epilepsy 21 | 792
ulcerative colitis 21 | 1,819
Breast Neoplasms 20 | 445
Liver carcinoma 20 | 240
astrocytoma 20 | 1,146
Duchenne muscular dystrophy 19 | 601
Mammary Neoplasms 19 | 425
Osteoporosis 19 | 363
Rheumatoid arthritis 19 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 19 | 510
ductal carcinoma in situ 19 | 1,745
Intellectual disability 18 | 1,016
pediatric high grade glioma 18 | 1,064
Kidney cancer 17 | 2,613
Liver Cirrhosis, Experimental 17 | 769
Muscle hypotonia 17 | 571
Parkinson's disease 17 | 392
Prostatic Neoplasms 17 | 495
Stomach Neoplasms 17 | 300
non primary Sjogren syndrome sicca 17 | 891
Animal Mammary Neoplasms 16 | 136
Depressive disorder 16 | 409
Down syndrome 16 | 499
Mammary Neoplasms, Animal 16 | 136
Mammary Neoplasms, Experimental 16 | 154
Seizures 16 | 596
interstitial cystitis 16 | 2,312
Bipolar Disorder 15 | 666
acute myeloid leukemia 15 | 783
gastric carcinoma 15 | 807
Adenocarcinoma of lung 14 | 142
Disease Models, Animal 14 | 155
HIV Infections 14 | 102
Neoplasm Invasiveness 14 | 161
adrenocortical carcinoma 14 | 1,428
Vascular disease 13 | 319
nasopharyngeal carcinoma 13 | 1,058
non-small cell lung carcinoma 13 | 317
progressive supranuclear palsy 13 | 676
Degenerative polyarthritis 12 | 115
Muscle Spasticity 12 | 195
Myocardial Ischemia 12 | 169
Neoplasm Metastasis 12 | 168
Neurodegenerative Disorders 12 | 79
Osteoarthritis 12 | 184
Acute coronary syndrome 11 | 39
Atopic dermatitis 11 | 952
Becker muscular dystrophy 11 | 191
Cerebellar Ataxia 11 | 304
Myopathy 11 | 185
Neuropathy 11 | 261
Global developmental delay 10 | 608

Tissue

Digestive Tract 208 | 17,369
Endocrine System 208 | 18,159
Female tissues 208 | 17,400
Skin and soft tissues 208 | 17,230
Blood and immune system 207 | 16,909
Liver and Pancreas 207 | 16,750
Male tissues 207 | 17,142
Nervous System 207 | 16,725
Urinary Tract 206 | 16,678
Respiratory system 205 | 16,393
Cardiovascular System 202 | 15,192

Target Family

Non-IDG 145 | 12,091
Enzyme 62 | 4,145
Kinase 6 | 634
Epigenetic 2 | 242

Jensen-KB Tissue

Brain cortex cell line 215 | 215
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
Nascent polypeptide-associated complex subunit alpha NACA Tbio Non-IDG -1.15827 23.3 50
Nascent polypeptide-associated complex subunit alpha, muscle-specific form NACA Tbio Non-IDG -1.15827 23.3 50
D-3-phosphoglycerate dehydrogenase PHGDH Tbio Enzyme -3.17330 1408.2 293
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.46124 30.0 217
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Fatty acid-binding protein, epidermal FABP5 Tchem Non-IDG -1.94229 141.2 226
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178