Development Level

Tbio 4,451 | 10,625
Tdark 1,799 | 7,003
Tchem 795 | 1,890
Tclin 263 | 602

Collection

Eligible Kinase Proteins 61 | 134
Eligible Ion Channel Proteins 57 | 117
Eligible non-olfactory GPCR Proteins 46 | 143

IMPC Term

preweaning lethality, complete... 283 | 633
preweaning lethality, incomple... 133 | 260
abnormal behavior 118 | 226
decreased lean body mass 96 | 195
decreased bone mineral content 89 | 157
decreased total body fat amoun... 89 | 186
decreased body weight 86 | 174
embryonic lethality prior to t... 80 | 187
abnormal bone structure 70 | 131
increased or absent threshold ... 66 | 128
increased circulating alkaline... 65 | 119
embryonic lethality prior to o... 62 | 148
hyperactivity 60 | 108
decreased grip strength 57 | 123
decreased bone mineral density 55 | 126
increased lean body mass 49 | 107
decreased circulating choleste... 48 | 85
abnormal retina morphology 47 | 100
decreased body length 46 | 108
decreased circulating glucose ... 46 | 121
increased mean corpuscular hem... 44 | 93
short tibia 44 | 82
decreased circulating HDL chol... 43 | 77
decreased circulating serum al... 43 | 79
increased mean corpuscular vol... 42 | 91
abnormal embryo size 41 | 112
increased bone mineral content 40 | 92
enlarged heart 39 | 111
hypoactivity 36 | 89
decreased circulating insulin ... 35 | 75
abnormal lens morphology 34 | 73
decreased circulating triglyce... 34 | 83
decreased lumbar vertebrae num... 34 | 62
increased fasted circulating g... 34 | 68
increased grip strength 33 | 83
abnormal retinal pigmentation 32 | 61
increased sacral vertebrae num... 31 | 62
increased total body fat amoun... 31 | 57
abnormal sleep behavior 30 | 63
decreased prepulse inhibition 30 | 52
increased circulating sodium l... 30 | 71
abnormal coat/hair pigmentatio... 29 | 54
increased circulating HDL chol... 29 | 63
male infertility 29 | 62
decreased circulating LDL chol... 28 | 37
decreased leukocyte cell numbe... 27 | 54
increased circulating choleste... 27 | 53
decreased rib number 26 | 59
prenatal lethality prior to he... 26 | 64
thrombocytopenia 26 | 46
decreased fasted circulating g... 25 | 49
decreased mean corpuscular vol... 25 | 50
improved glucose tolerance 25 | 56
abnormal bone mineralization 24 | 55
decreased caudal vertebrae num... 24 | 49
decreased circulating alanine ... 24 | 53
decreased circulating alkaline... 24 | 41
decreased hemoglobin content 24 | 53
increased circulating chloride... 24 | 43
decreased heart weight 23 | 44
decreased startle reflex 23 | 48
impaired glucose tolerance 23 | 52
increased bone mineral density 23 | 52
increased exploration in new e... 23 | 56
abnormal gait 22 | 51
decreased circulating total pr... 22 | 41
increased body weight 21 | 42
increased hemoglobin content 21 | 45
abnormal behavioral response t... 20 | 52
increased blood urea nitrogen ... 20 | 44
abnormal cranium morphology 19 | 32
abnormal eye morphology 19 | 38
decreased B cell number 19 | 30
increased rib number 19 | 41
increased startle reflex 19 | 38
abnormal seminal vesicle morph... 18 | 47
decreased circulating calcium ... 18 | 33
decreased circulating free fat... 18 | 39
decreased mean corpuscular hem... 18 | 34
increased heart weight 18 | 37
increased leukocyte cell numbe... 18 | 37
tremors 18 | 34
corneal opacity 17 | 25
decreased circulating fructosa... 17 | 31
limb grasping 17 | 35
abnormal epididymis morphology 16 | 31
female infertility 16 | 34
increased circulating calcium ... 16 | 32
increased circulating iron lev... 16 | 25
increased circulating potassiu... 16 | 31
increased hematocrit 16 | 36
abnormal neural tube closure 15 | 37
abnormal rib morphology 15 | 28
abnormal spleen morphology 15 | 36
cardiovascular system phenotyp... 15 | 35
decreased erythrocyte cell num... 15 | 43
straub tail 15 | 26
decreased NK T cell number 14 | 28
decreased circulating aspartat... 14 | 27
increased circulating serum al... 14 | 25

Disease

ovarian cancer 3,767 | 8,484
osteosarcoma 3,424 | 7,933
medulloblastoma, large-cell 3,101 | 6,234
glioblastoma 2,769 | 5,572
psoriasis 2,656 | 6,685
atypical teratoid / rhabdoid tumor 2,275 | 4,369
lung cancer 1,909 | 4,466
pilocytic astrocytoma 1,650 | 3,086
oligodendroglioma 1,636 | 2,849
primitive neuroectodermal tumor 1,624 | 3,031
ependymoma 1,418 | 2,514
malignant mesothelioma 1,376 | 3,162
Breast cancer 1,362 | 3,094
pediatric high grade glioma 1,348 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 1,325 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 1,271 | 2,988
lung carcinoma 1,259 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 1,255 | 2,956
astrocytic glioma 1,240 | 2,241
invasive ductal carcinoma 1,221 | 2,950
subependymal giant cell astrocytoma 1,187 | 2,287
Carcinoma 1,146 | 2,147
Pick disease 1,141 | 1,893
non-small cell lung cancer 1,114 | 2,798
adult high grade glioma 1,098 | 2,148
lung adenocarcinoma 1,069 | 2,713
group 3 medulloblastoma 1,022 | 2,254
pituitary cancer 947 | 1,972
group 4 medulloblastoma 934 | 1,875
pancreatic cancer 900 | 2,300
interstitial cystitis 869 | 2,299
medulloblastoma 849 | 1,524
Cancer 847 | 2,346
astrocytoma 811 | 1,493
ulcerative colitis 808 | 2,087
sonic hedgehog group medulloblastoma 730 | 1,482
cystic fibrosis 719 | 1,665
posterior fossa group B ependymoma 701 | 1,530
posterior fossa group A ependymoma 698 | 1,511
pancreatic ductal adenocarcinoma liver metastasis 691 | 1,795
ductal carcinoma in situ 678 | 1,745
breast carcinoma 676 | 1,614
colon cancer 621 | 1,475
tuberculosis 609 | 1,557
Multiple myeloma 605 | 1,327
adrenocortical carcinoma 600 | 1,427
atypical teratoid/rhabdoid tumor 553 | 1,095
primary pancreatic ductal adenocarcinoma 541 | 1,271
juvenile dermatomyositis 535 | 1,189
acute quadriplegic myopathy 521 | 1,157
diabetes mellitus 509 | 1,663
Rheumatoid Arthritis 484 | 1,160
dermatomyositis 435 | 933
spina bifida 430 | 1,064
cutaneous lupus erythematosus 387 | 1,056
Alzheimer's disease 372 | 644
progressive supranuclear palsy 358 | 674
active Crohn's disease 351 | 918
Waldenstrons macroglobulinemia 349 | 765
nasopharyngeal carcinoma 349 | 1,056
gastric carcinoma 347 | 832
Intellectual disability 338 | 573
non primary Sjogren syndrome sicca 335 | 840
acute myeloid leukemia 329 | 780
aldosterone-producing adenoma 319 | 664
Atopic dermatitis 312 | 944
tuberculosis and treatment for 6 months 308 | 686
Down syndrome 285 | 548
primary Sjogren syndrome 282 | 789
Schizophrenia 279 | 501
Duchenne muscular dystrophy 263 | 602
esophageal adenocarcinoma 259 | 737
Obesity 254 | 616
autosomal dominant Emery-Dreifuss muscular dystrophy 239 | 499
pancreatic carcinoma 234 | 567
Amyotrophic Lateral Sclerosis 233 | 431
Neurodegenerative disease 231 | 383
Parkinson's disease 216 | 364
fibroadenoma 216 | 557
Epilepsy 210 | 346
hepatocellular carcinoma 208 | 532
chronic rhinosinusitis 204 | 512
active ulcerative colitis 179 | 477
glioblastoma multiforme 179 | 347
Autistic Disorder 178 | 320
Endometriosis 178 | 535
Multiple Sclerosis 176 | 498
gastric cancer 176 | 430
hereditary spastic paraplegia 174 | 313
mucosa-associated lymphoid tissue lymphoma 172 | 480
Prostatic Neoplasms 167 | 471
Mammary Neoplasms 166 | 410
IGA Glomerulonephritis 164 | 454
inflammatory breast cancer 150 | 404
Bipolar Disorder 145 | 266
non-small cell lung carcinoma 137 | 413
sarcoidosis 134 | 358
tuberculosis and treatment for 3 months 134 | 327
interstitial lung disease 132 | 291
Crohn's disease 129 | 304

Tissue

Nervous System 7,217 | 18,561
Female tissues 7,210 | 18,647
Digestive Tract 7,197 | 18,473
Endocrine System 7,194 | 18,512
Urinary Tract 7,192 | 18,444
Liver and Pancreas 7,173 | 18,136
Male tissues 7,148 | 17,969
Cardiovascular System 7,147 | 17,958
Blood and immune system 7,133 | 17,995
Skin and soft tissues 7,132 | 18,115
Respiratory system 7,067 | 17,484

Target Family

Non-IDG 4,075 | 11,971
Enzyme 1,723 | 4,146
Transcription Factor 519 | 1,400
Kinase 295 | 634
Transporter 186 | 473
Ion Channel 176 | 341
GPCR 165 | 406
Epigenetic 123 | 242
Nuclear Receptor 16 | 48
TF/Epigenetic 15 | 38
oGPCR 15 | 421

Jensen-KB Tissue

Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial 2-oxodicarboxylate carrier SLC25A21 Tbio Transporter -0.46900 2.68 102
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
RNA pseudouridylate synthase domain-containing protein 3 RPUSD3 Tdark Enzyme 0.42 34
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Zinc finger protein 485 ZNF485 Tdark Transcription Factor 0.00000 48
ADP/ATP translocase 3 SLC25A6 Tbio Transporter -2.06581 118.3 193
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359