Development Level

Tbio 484 | 11,445
Tdark 86 | 6,588
Tchem 54 | 1,598
Tclin 12 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 50 | 979
embryonic lethality prior to t... 17 | 278
embryonic lethality prior to o... 16 | 239
preweaning lethality, incomple... 16 | 499
abnormal bone structure 14 | 187
decreased body weight 14 | 161
abnormal embryo size 13 | 220
decreased total body fat amoun... 12 | 207
abnormal behavior 10 | 298
increased lean body mass 10 | 172
increased startle reflex 10 | 112
decreased circulating glucose ... 8 | 126
decreased vertical activity 8 | 208
increased heart weight 8 | 62
embryonic growth retardation 7 | 106
hypoactivity 7 | 132
impaired glucose tolerance 7 | 75
abnormal retina morphology 6 | 71
decreased bone mineral content 6 | 151
decreased bone mineral density 6 | 126
increased circulating alkaline... 6 | 122
increased circulating calcium ... 6 | 34
increased or absent threshold ... 6 | 101
abnormal gait 5 | 69
abnormal kidney morphology 5 | 65
decreased lean body mass 5 | 135
decreased prepulse inhibition 5 | 82
enlarged heart 5 | 210
increased bone mineral content 5 | 108
increased circulating choleste... 5 | 66
limb grasping 5 | 41
abnormal lens morphology 4 | 81
abnormal sleep behavior 4 | 70
cataract 4 | 92
decreased circulating alanine ... 4 | 47
decreased circulating choleste... 4 | 93
decreased circulating serum al... 4 | 82
decreased circulating triglyce... 4 | 79
decreased erythrocyte cell num... 4 | 62
decreased hemoglobin content 4 | 68
decreased mean corpuscular vol... 4 | 79
decreased startle reflex 4 | 75
enlarged lymph nodes 4 | 37
hyperactivity 4 | 148
increased circulating HDL chol... 4 | 80
increased circulating chloride... 4 | 41
increased circulating sodium l... 4 | 71
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
prenatal lethality prior to he... 4 | 87
prolonged QT interval 4 | 38
short tibia 4 | 97
abnormal coat appearance 3 | 31
abnormal coat-hair pigmentatio... 3 | 64
abnormal embryo turning 3 | 31
decreased body length 3 | 101
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating alkaline... 3 | 46
decreased grip strength 3 | 116
decreased leukocyte cell numbe... 3 | 73
decreased red blood cell distr... 3 | 41
edema 3 | 59
increased bone mineral density 3 | 72
increased circulating glucose ... 3 | 24
increased circulating serum al... 3 | 22
increased circulating total pr... 3 | 28
increased erythrocyte cell num... 3 | 39
increased fasted circulating g... 3 | 76
increased total body fat amoun... 3 | 134
male infertility 3 | 123
prenatal lethality 3 | 28
prolonged ST segment 3 | 36
small testis 3 | 58
thrombocytosis 3 | 27
abnormal bone mineralization 2 | 38
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
decreased circulating chloride... 2 | 30
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased food intake 2 | 13
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating free fat... 2 | 20
increased circulating potassiu... 2 | 29
increased circulating triglyce... 2 | 42
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
pale yolk sac 2 | 25
pallor 2 | 34

Disease

Carcinoma 402 | 11,493
ovarian cancer 395 | 8,520
osteosarcoma 329 | 7,950
lung cancer 269 | 4,740
medulloblastoma, large-cell 257 | 6,241
glioblastoma 245 | 5,792
psoriasis 236 | 6,694
atypical teratoid / rhabdoid tumor 185 | 5,112
ependymoma 155 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 153 | 3,291
group 3 medulloblastoma 151 | 4,104
malignant mesothelioma 149 | 3,232
Breast cancer 139 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 137 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 123 | 2,955
non-small cell lung cancer 122 | 2,890
lung adenocarcinoma 121 | 2,716
adult high grade glioma 120 | 3,801
Kidney cancer 116 | 2,613
Cancer 110 | 2,499
primitive neuroectodermal tumor 109 | 3,035
invasive ductal carcinoma 106 | 2,951
oligodendroglioma 106 | 2,850
Multiple myeloma 99 | 1,332
Astrocytoma, Pilocytic 94 | 3,081
pancreatic cancer 89 | 2,398
astrocytic glioma 88 | 2,597
subependymal giant cell astrocytoma 88 | 2,287
tuberculosis 87 | 2,010
interstitial cystitis 81 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 80 | 1,962
astrocytoma 79 | 1,146
lung carcinoma 79 | 2,843
group 4 medulloblastoma 76 | 1,855
ulcerative colitis 76 | 1,819
dermatomyositis 73 | 966
Waldenstrons macroglobulinemia 72 | 765
colon cancer 72 | 1,478
Pick disease 71 | 1,894
acute quadriplegic myopathy 62 | 1,158
ductal carcinoma in situ 62 | 1,745
Autosomal recessive predisposition 59 | 1,442
breast carcinoma 58 | 1,638
juvenile dermatomyositis 58 | 1,187
pediatric high grade glioma 55 | 1,064
cystic fibrosis 54 | 1,696
diabetes mellitus 54 | 1,728
pituitary cancer 54 | 1,972
adrenocortical carcinoma 50 | 1,428
primary Sjogren syndrome 50 | 735
Rheumatoid arthritis 49 | 1,191
acute myeloid leukemia 49 | 783
nasopharyngeal carcinoma 48 | 1,058
Intellectual disability 43 | 1,016
cutaneous lupus erythematosus 43 | 1,057
primary pancreatic ductal adenocarcinoma 41 | 1,109
progressive supranuclear palsy 40 | 676
Cognitive delay 39 | 608
Global developmental delay 39 | 608
Mental and motor retardation 39 | 608
Atopic dermatitis 37 | 952
gastric carcinoma 36 | 807
spina bifida 36 | 1,074
Liver Cirrhosis, Experimental 35 | 769
Schizophrenia 34 | 1,160
non primary Sjogren syndrome sicca 34 | 891
Dull intelligence 32 | 645
Low intelligence 32 | 645
Mental Retardation 32 | 645
Mental deficiency 32 | 645
Poor school performance 32 | 645
Down syndrome 31 | 499
Muscle hypotonia 29 | 571
Short stature 29 | 531
active Crohn's disease 29 | 922
esophageal adenocarcinoma 29 | 737
aldosterone-producing adenoma 28 | 665
mucosa-associated lymphoid tissue lymphoma 28 | 484
Duchenne muscular dystrophy 27 | 601
Epilepsy 26 | 792
hereditary spastic paraplegia 26 | 318
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 510
medulloblastoma 24 | 720
Endometriosis 23 | 540
Seizures 22 | 596
hepatocellular carcinoma 22 | 547
Alzheimer's disease 21 | 658
Melanoma 21 | 711
Obesity 21 | 678
active ulcerative colitis 21 | 764
tuberculosis and treatment for 6 months 21 | 409
Bipolar Disorder 20 | 666
Small head 19 | 374
pancreatic carcinoma 19 | 562
Hypoplastic mandible condyle 18 | 275
Mandibular hypoplasia 18 | 275
Micrognathism 18 | 275
Polycystic ovary syndrome 18 | 360
sonic hedgehog group medulloblastoma 18 | 467
Cleft Palate 17 | 271

Tissue

Blood and immune system 623 | 16,909
Endocrine System 623 | 18,159
Female tissues 622 | 17,400
Skin and soft tissues 622 | 17,230
Digestive Tract 621 | 17,369
Respiratory system 617 | 16,393
Liver and Pancreas 614 | 16,750
Male tissues 614 | 17,142
Nervous System 612 | 16,725
Urinary Tract 612 | 16,678
Cardiovascular System 599 | 15,192

Target Family

Non-IDG 383 | 12,091
Enzyme 162 | 4,145
Transcription Factor 42 | 1,400
Epigenetic 15 | 242
Kinase 13 | 634
GPCR 6 | 408
Ion Channel 6 | 344
Transporter 5 | 473
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Bone marrow 636 | 636
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Zinc finger protein 142 ZNF142 Tbio Transcription Factor 0.05 0.69 17
Pregnancy-specific beta-1-glycoprotein 4 PSG4 Tbio Non-IDG -0.83904 10.5 68
Pregnancy-specific beta-1-glycoprotein 6 PSG6 Tbio Non-IDG -0.94199 8.65 114
Linker for activation of T-cells family member 1 LAT Tbio Non-IDG -2.16291 169.4 667
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
HMG domain-containing protein 3 HMGXB3 Tdark Transcription Factor -0.15127 1.49 73
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Sterol regulatory element-binding protein cleavage-activating protein SCAP Tbio Non-IDG -1.85010 73.9 172
Transmembrane protein 94 TMEM94 Tdark Non-IDG 0.48 0.33 23