Development Level

Tbio 408 | 11,651
Tchem 77 | 1,388
Tdark 29 | 6,593
Tclin 24 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 52 | 979
preweaning lethality, incomple... 25 | 499
embryonic lethality prior to t... 13 | 278
embryonic lethality prior to o... 12 | 239
abnormal embryo size 11 | 220
decreased total body fat amoun... 10 | 207
abnormal behavior 9 | 298
enlarged heart 9 | 210
decreased body weight 8 | 161
decreased vertical activity 8 | 208
abnormal heart morphology 6 | 162
decreased bone mineral content 6 | 151
decreased circulating total pr... 6 | 49
edema 6 | 59
abnormal bone structure 5 | 187
decreased caudal vertebrae num... 5 | 53
decreased circulating choleste... 5 | 93
decreased mean corpuscular vol... 5 | 79
embryonic growth retardation 5 | 106
hyperactivity 5 | 148
increased blood urea nitrogen ... 5 | 48
increased circulating alkaline... 5 | 122
increased lean body mass 5 | 172
male infertility 5 | 123
pallor 5 | 34
short tibia 5 | 97
thrombocytopenia 5 | 56
abnormal seminal vesicle morph... 4 | 114
cardiovascular system phenotyp... 4 | 36
decreased body length 4 | 101
decreased circulating HDL chol... 4 | 68
decreased circulating LDL chol... 4 | 38
decreased circulating alanine ... 4 | 47
decreased circulating serum al... 4 | 82
decreased erythrocyte cell num... 4 | 62
decreased mean corpuscular hem... 4 | 50
hemorrhage 4 | 23
increased bone mineral content 4 | 108
increased mean platelet volume 4 | 45
increased red blood cell distr... 4 | 34
prenatal lethality prior to he... 4 | 87
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
abnormal embryo turning 3 | 31
abnormal eye morphology 3 | 68
abnormal femur morphology 3 | 14
abnormal forebrain morphology 3 | 10
abnormal lens morphology 3 | 81
abnormal neural tube closure 3 | 46
abnormal sleep behavior 3 | 70
abnormal tail morphology 3 | 25
anophthalmia 3 | 33
decreased bone mineral density 3 | 126
decreased circulating aspartat... 3 | 34
decreased circulating calcium ... 3 | 36
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
enlarged lymph nodes 3 | 37
hydrometra 3 | 53
increased grip strength 3 | 41
increased mean corpuscular hem... 3 | 36
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
persistence of hyaloid vascula... 3 | 33
small testis 3 | 58
abnormal coat-hair pigmentatio... 2 | 64
abnormal craniofacial morpholo... 2 | 33
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal retinal vasculature m... 2 | 27
decreased circulating iron lev... 2 | 32
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 31
enlarged spleen 2 | 41
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
vertebral fusion 2 | 23

Disease

Carcinoma 372 | 11,493
ovarian cancer 333 | 8,520
osteosarcoma 302 | 7,950
glioblastoma 229 | 5,792
medulloblastoma, large-cell 217 | 6,241
psoriasis 214 | 6,694
lung cancer 184 | 4,740
atypical teratoid / rhabdoid tumor 179 | 5,112
Cancer 159 | 2,499
ependymoma 156 | 4,679
pancreatic cancer 132 | 2,398
adult high grade glioma 131 | 3,801
Breast cancer 129 | 3,578
Astrocytoma, Pilocytic 124 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 124 | 3,291
diabetes mellitus 119 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 119 | 2,955
invasive ductal carcinoma 116 | 2,951
group 3 medulloblastoma 110 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 110 | 2,989
non-small cell lung cancer 108 | 2,890
lung carcinoma 107 | 2,843
subependymal giant cell astrocytoma 107 | 2,287
tuberculosis 106 | 2,010
lung adenocarcinoma 103 | 2,716
malignant mesothelioma 103 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 93 | 1,962
Kidney cancer 92 | 2,613
oligodendroglioma 92 | 2,850
Multiple myeloma 90 | 1,332
primitive neuroectodermal tumor 90 | 3,035
ulcerative colitis 80 | 1,819
interstitial cystitis 78 | 2,312
astrocytic glioma 77 | 2,597
astrocytoma 75 | 1,146
group 4 medulloblastoma 74 | 1,855
acute quadriplegic myopathy 70 | 1,158
juvenile dermatomyositis 68 | 1,187
Pick disease 66 | 1,894
primary pancreatic ductal adenocarcinoma 66 | 1,109
colon cancer 65 | 1,478
Rheumatoid arthritis 62 | 1,191
cystic fibrosis 60 | 1,696
Schizophrenia 59 | 1,160
Autosomal recessive predisposition 58 | 1,442
dermatomyositis 58 | 966
Waldenstrons macroglobulinemia 56 | 765
Liver Cirrhosis, Experimental 54 | 769
ductal carcinoma in situ 54 | 1,745
breast carcinoma 53 | 1,638
pediatric high grade glioma 51 | 1,064
Kidney disease 49 | 430
adrenocortical carcinoma 47 | 1,428
spina bifida 47 | 1,074
pancreatic carcinoma 46 | 562
gastric carcinoma 45 | 807
esophageal adenocarcinoma 42 | 737
Duchenne muscular dystrophy 40 | 601
pituitary cancer 40 | 1,972
Intellectual disability 39 | 1,016
Alzheimer's disease 38 | 658
Anemia 38 | 365
Down syndrome 38 | 499
autosomal dominant Emery-Dreifuss muscular dystrophy 37 | 510
mucosa-associated lymphoid tissue lymphoma 37 | 484
Arthritis 36 | 290
Hypertension 36 | 396
Liver disease 35 | 237
acute myeloid leukemia 35 | 783
Bipolar Disorder 34 | 666
cutaneous lupus erythematosus 34 | 1,057
Multiple Sclerosis 33 | 540
aldosterone-producing adenoma 33 | 665
primary Sjogren syndrome 31 | 735
Hypersensitivity reaction type II disease 30 | 253
Neurodegenerative disease 29 | 414
Osteoporosis 29 | 363
Prostatic Neoplasms 28 | 495
Short stature 28 | 531
Vascular disease 28 | 319
medulloblastoma 28 | 720
non primary Sjogren syndrome sicca 28 | 891
Acquired immunodeficiency syndrome 27 | 197
Amyotrophic lateral sclerosis 27 | 451
Dull intelligence 27 | 645
Low intelligence 27 | 645
Mental Retardation 27 | 645
Mental deficiency 27 | 645
Muscle hypotonia 27 | 571
Poor school performance 27 | 645
Thrombocytopenia 27 | 197
Atopic dermatitis 26 | 952
Cerebrovascular disease 26 | 238
Coronary artery disease 26 | 268
Epilepsy 26 | 792
Hypertensive disease 26 | 292
Leprosy 26 | 73
Obesity 26 | 678
Parkinson's disease 26 | 392
Skin disease 26 | 66

Tissue

Endocrine System 510 | 18,159
Digestive Tract 509 | 17,369
Skin and soft tissues 509 | 17,230
Blood and immune system 508 | 16,909
Female tissues 506 | 17,400
Liver and Pancreas 506 | 16,750
Male tissues 506 | 17,142
Urinary Tract 506 | 16,678
Respiratory system 505 | 16,393
Nervous System 499 | 16,725
Cardiovascular System 496 | 15,192

Target Family

Non-IDG 350 | 12,091
Enzyme 127 | 4,145
Kinase 37 | 634
Transporter 8 | 473
Transcription Factor 5 | 1,400
GPCR 4 | 408
Ion Channel 4 | 344
Epigenetic 3 | 242

Jensen-KB Tissue

Blood platelet 538 | 538
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
STE20/SPS1-related proline-alanine-rich protein kinase STK39 Tbio Kinase -2.11714 148.9 575
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A Tclin Enzyme -2.09039 125.7 168