Development Level

Tbio 391 | 11,651
Tchem 85 | 1,388
Tdark 51 | 6,593
Tclin 40 | 612

Collection

RFA-RM-18-021 7 | 328
Ion Channel: IDG Consortium (T... 4 | 99
GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 35 | 979
embryonic lethality prior to t... 17 | 278
decreased vertical activity 11 | 208
abnormal embryo size 9 | 220
embryonic lethality prior to o... 9 | 239
preweaning lethality, incomple... 8 | 499
abnormal behavior 7 | 298
abnormal bone structure 7 | 187
decreased lymphocyte cell numb... 7 | 83
abnormal heart morphology 6 | 162
decreased bone mineral content 6 | 151
enlarged heart 6 | 210
increased total body fat amoun... 6 | 134
abnormal seminal vesicle morph... 5 | 114
decreased blood urea nitrogen ... 5 | 51
decreased body weight 5 | 161
decreased circulating choleste... 5 | 93
embryonic growth retardation 5 | 106
increased bone mineral density 5 | 72
increased circulating alkaline... 5 | 122
abnormal skin morphology 4 | 50
decreased body length 4 | 101
decreased circulating serum al... 4 | 82
decreased lean body mass 4 | 135
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
decreased startle reflex 4 | 75
increased circulating triglyce... 4 | 42
increased erythrocyte cell num... 4 | 39
increased lean body mass 4 | 172
increased mean corpuscular hem... 4 | 96
increased monocyte cell number 4 | 63
increased prepulse inhibition 4 | 32
increased startle reflex 4 | 112
prenatal lethality prior to he... 4 | 87
abnormal sleep behavior 3 | 70
abnormal tooth morphology 3 | 24
decreased circulating HDL chol... 3 | 68
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating calcium ... 3 | 36
decreased circulating creatini... 3 | 39
decreased circulating sodium l... 3 | 22
decreased circulating total pr... 3 | 49
decreased total body fat amoun... 3 | 207
hyperactivity 3 | 148
increased blood urea nitrogen ... 3 | 48
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased hemoglobin content 3 | 45
male infertility 3 | 123
pale yolk sac 3 | 25
short tibia 3 | 97
small superior vagus ganglion 3 | 74
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal forebrain morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal limb bud morphology 2 | 17
abnormal lung morphology 2 | 26
abnormal midbrain morphology 2 | 10
abnormal pericardium morpholog... 2 | 26
abnormal placenta size 2 | 20
abnormal testis morphology 2 | 43
abnormal vibrissa morphology 2 | 25
cataract 2 | 92
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 50
decreased red blood cell distr... 2 | 41
edema 2 | 59
enlarged epididymis 2 | 31
enlarged lymph nodes 2 | 37
hemorrhage 2 | 23
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating potassiu... 2 | 29
increased circulating serum al... 2 | 22
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
long tibia 2 | 25
pallor 2 | 34
small adrenal glands 2 | 16
small testis 2 | 58
small thymus 2 | 16
thrombocytosis 2 | 27
abnormal gait 1 | 69
increased cardiac muscle contr... 1 | 8

Disease

Carcinoma 323 | 11,493
psoriasis 276 | 6,694
osteosarcoma 255 | 7,950
ovarian cancer 251 | 8,520
Cancer 211 | 2,499
glioblastoma 173 | 5,792
lung cancer 168 | 4,740
medulloblastoma, large-cell 154 | 6,241
tuberculosis 141 | 2,010
lung carcinoma 130 | 2,843
diabetes mellitus 125 | 1,728
non-small cell lung cancer 123 | 2,890
atypical teratoid / rhabdoid tumor 120 | 5,112
interstitial cystitis 120 | 2,312
malignant mesothelioma 119 | 3,232
ependymoma 117 | 4,679
Astrocytoma, Pilocytic 108 | 3,081
adult high grade glioma 105 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 103 | 2,955
invasive ductal carcinoma 102 | 2,951
lung adenocarcinoma 100 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 99 | 3,291
Rheumatoid arthritis 95 | 1,191
intraductal papillary-mucinous carcinoma (IPMC) 95 | 2,989
Breast cancer 93 | 3,578
group 3 medulloblastoma 89 | 4,104
ulcerative colitis 89 | 1,819
Hypersensitivity reaction type II disease 86 | 253
pancreatic cancer 86 | 2,398
Arthritis 83 | 290
subependymal giant cell astrocytoma 78 | 2,287
oligodendroglioma 77 | 2,850
Ankylosing spondylitis 76 | 140
cutaneous lupus erythematosus 75 | 1,057
Behcet's disease 74 | 89
dermatomyositis 72 | 966
Acquired immunodeficiency syndrome 69 | 197
Human immunodeficiency virus infectious disease 69 | 138
breast carcinoma 69 | 1,638
Multiple Sclerosis 67 | 540
primitive neuroectodermal tumor 66 | 3,035
cystic fibrosis 64 | 1,696
Juvenile rheumatoid arthritis 63 | 111
Uveitis 63 | 103
ductal carcinoma in situ 62 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 62 | 1,962
Herpes zoster 59 | 68
astrocytic glioma 59 | 2,597
Autosomal recessive predisposition 57 | 1,442
Kidney cancer 57 | 2,613
Psoriatic arthritis 57 | 86
Dermatitis 53 | 157
pituitary cancer 53 | 1,972
Stevens-Johnson syndrome 52 | 92
adrenocortical carcinoma 52 | 1,428
primary Sjogren syndrome 52 | 735
Schizophrenia 51 | 1,160
Kidney disease 48 | 430
Anemia 47 | 365
group 4 medulloblastoma 47 | 1,855
juvenile dermatomyositis 47 | 1,187
Pick disease 44 | 1,894
mucosa-associated lymphoid tissue lymphoma 44 | 484
colon cancer 43 | 1,478
Liver disease 42 | 237
Synovitis 41 | 78
acute quadriplegic myopathy 41 | 1,158
Atopic dermatitis 40 | 952
Multiple myeloma 40 | 1,332
astrocytoma 40 | 1,146
nasopharyngeal carcinoma 40 | 1,058
Asthma 38 | 385
Behcet's syndrome 38 | 50
Hepatitis B 38 | 108
Congenital adrenal hyperplasia 37 | 73
active Crohn's disease 37 | 922
primary pancreatic ductal adenocarcinoma 37 | 1,109
Liver Cirrhosis, Experimental 36 | 769
Nephritis 36 | 51
Takayasu's arteritis 36 | 53
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
Alzheimer's disease 34 | 658
Waldenstrons macroglobulinemia 34 | 765
acute myeloid leukemia 33 | 783
esophageal adenocarcinoma 32 | 737
Leprosy 31 | 73
sarcoidosis 31 | 370
Bipolar Disorder 30 | 666
Obesity 30 | 678
Hypertension 29 | 396
Prostatic Neoplasms 29 | 495
hepatocellular carcinoma 29 | 547
pancreatic carcinoma 29 | 562
spina bifida 29 | 1,074
Atherosclerosis 28 | 291
Duchenne muscular dystrophy 28 | 601
Epilepsy 28 | 792
gastric carcinoma 28 | 807

Tissue

Endocrine System 480 | 18,159
Skin and soft tissues 478 | 17,230
Blood and immune system 477 | 16,909
Digestive Tract 476 | 17,369
Urinary Tract 475 | 16,678
Female tissues 473 | 17,400
Liver and Pancreas 471 | 16,750
Male tissues 470 | 17,142
Respiratory system 465 | 16,393
Nervous System 451 | 16,725
Cardiovascular System 441 | 15,192

Target Family

Non-IDG 346 | 12,091
Enzyme 105 | 4,145
Kinase 34 | 634
GPCR 23 | 408
Transcription Factor 19 | 1,400
Transporter 16 | 473
Ion Channel 13 | 344
Epigenetic 5 | 242
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Blood 567 | 567
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
60S ribosomal protein L17 RPL17 Tbio Non-IDG -1.22337 16.5 217
cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A Tclin Enzyme -2.09039 125.7 168
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H PIGH Tbio Enzyme -1.19063 13.0 116
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
CMRF35-like molecule 7 CD300LB Tbio Non-IDG -0.85242 10.4 74
Glycerol kinase 3 GK3P Tdark Kinase -1.84692 109.0 0