Development Level

Tbio 351 | 10,625
Tchem 107 | 1,890
Tdark 71 | 7,003
Tclin 40 | 602

Collection

Ion Channel: IDG Consortium (Targets) 4 | 102
GPCR: IDG Consortium (Targets) 2 | 127
GPCR: IDG Consortium (Complete/Control) 1 | 26
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 25 | 633
embryonic lethality prior to t... 11 | 187
decreased bone mineral content 8 | 157
decreased circulating serum al... 7 | 79
abnormal behavior 6 | 226
preweaning lethality, incomple... 6 | 260
decreased body weight 5 | 174
decreased circulating choleste... 5 | 85
decreased total body fat amoun... 5 | 186
embryonic lethality prior to o... 5 | 148
increased hemoglobin content 5 | 45
abnormal bone structure 4 | 131
abnormal retina morphology 4 | 100
decreased bone mineral density 4 | 126
decreased circulating total pr... 4 | 41
decreased lean body mass 4 | 195
increased bone mineral density 4 | 52
increased circulating alkaline... 4 | 119
increased circulating choleste... 4 | 53
increased mean corpuscular hem... 4 | 93
abnormal embryo size 3 | 112
abnormal sleep behavior 3 | 63
abnormal tooth morphology 3 | 24
decreased body length 3 | 108
decreased circulating HDL chol... 3 | 77
decreased circulating alanine ... 3 | 53
decreased leukocyte cell numbe... 3 | 54
decreased mean corpuscular vol... 3 | 50
enlarged heart 3 | 111
hyperactivity 3 | 108
increased blood urea nitrogen ... 3 | 44
increased bone mineral content 3 | 92
increased grip strength 3 | 83
increased or absent threshold ... 3 | 128
increased prepulse inhibition 3 | 21
prenatal lethality prior to he... 3 | 64
short tibia 3 | 82
small testis 3 | 37
tremors 3 | 34
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal limb bud morphology 2 | 15
abnormal skin morphology 2 | 23
abnormal testis morphology 2 | 30
decreased Ly6C low monocyte nu... 2 | 23
decreased blood urea nitrogen ... 2 | 31
decreased circulating LDL chol... 2 | 37
decreased circulating aspartat... 2 | 27
decreased circulating calcium ... 2 | 33
decreased circulating creatini... 2 | 31
decreased circulating fructosa... 2 | 31
decreased circulating glucose ... 2 | 121
decreased circulating sodium l... 2 | 18
decreased eosinophil cell numb... 2 | 41
decreased grip strength 2 | 123
decreased heart weight 2 | 44
decreased lumbar vertebrae num... 2 | 62
decreased lymphocyte cell numb... 2 | 9
decreased mean corpuscular hem... 2 | 34
decreased neutrophil cell numb... 2 | 37
enlarged epididymis 2 | 27
increased circulating HDL chol... 2 | 63
increased circulating chloride... 2 | 43
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased circulating triglyce... 2 | 24
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased lean body mass 2 | 107
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 25
increased mean corpuscular vol... 2 | 91
increased red blood cell distr... 2 | 21
increased total body fat amoun... 2 | 57
small superior vagus ganglion 2 | 20
thrombocytosis 2 | 23
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal vocalization 1 | 21
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased hemoglobin content 1 | 53
decreased red blood cell distr... 1 | 11
hydrometra 1 | 13
hydrops fetalis 1 | 22
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
long tibia 1 | 13
prolonged PR interval 1 | 4
small thymus 1 | 11

Disease

psoriasis 277 | 6,685
osteosarcoma 258 | 7,933
ovarian cancer 253 | 8,491
Cancer 207 | 2,346
lung cancer 168 | 4,473
glioblastoma 164 | 5,572
medulloblastoma, large-cell 156 | 6,234
lung carcinoma 132 | 2,844
diabetes mellitus 126 | 1,663
interstitial cystitis 120 | 2,299
non-small cell lung cancer 120 | 2,798
malignant mesothelioma 117 | 3,163
ulcerative colitis 109 | 2,087
pilocytic astrocytoma 104 | 3,086
atypical teratoid / rhabdoid tumor 103 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 103 | 2,956
invasive ductal carcinoma 102 | 2,950
tuberculosis 102 | 1,563
lung adenocarcinoma 101 | 2,714
intraductal papillary-mucinous neoplasm (IPMN) 100 | 3,289
Rheumatoid Arthritis 96 | 1,170
intraductal papillary-mucinous carcinoma (IPMC) 95 | 2,988
pancreatic cancer 86 | 2,300
Hypersensitivity reaction type II disease 85 | 235
Breast cancer 80 | 3,098
Arthritis 79 | 248
subependymal giant cell astrocytoma 79 | 2,287
oligodendroglioma 78 | 2,849
Ankylosing spondylitis 76 | 138
cutaneous lupus erythematosus 76 | 1,056
dermatomyositis 74 | 966
adult high grade glioma 71 | 2,148
Acquired immunodeficiency syndrome 69 | 164
Human immunodeficiency virus infectious disease 68 | 129
breast carcinoma 67 | 1,614
primitive neuroectodermal tumor 67 | 3,031
Multiple Sclerosis 65 | 498
Uveitis 64 | 103
ductal carcinoma in situ 63 | 1,745
ependymoma 63 | 2,514
Juvenile rheumatoid arthritis 62 | 105
cystic fibrosis 62 | 1,670
pediatric high grade glioma 62 | 2,712
Behcet's disease 60 | 74
posterior fossa group A ependymoma 59 | 1,511
Psoriatic arthritis 56 | 85
pancreatic ductal adenocarcinoma liver metastasis 55 | 1,795
pituitary cancer 55 | 1,972
astrocytic glioma 54 | 2,241
Dermatitis 53 | 141
primary Sjogren syndrome 53 | 788
Stevens-Johnson syndrome 52 | 91
adrenocortical carcinoma 52 | 1,427
group 4 medulloblastoma 50 | 1,875
Kidney disease 49 | 397
group 3 medulloblastoma 49 | 2,254
juvenile dermatomyositis 47 | 1,189
astrocytoma 46 | 1,493
Pick disease 45 | 1,893
medulloblastoma 45 | 1,524
colon cancer 44 | 1,475
mucosa-associated lymphoid tissue lymphoma 44 | 480
primary pancreatic ductal adenocarcinoma 44 | 1,271
Anemia 43 | 252
acute quadriplegic myopathy 42 | 1,157
Liver disease 41 | 219
Synovitis 41 | 72
Atopic dermatitis 40 | 944
Multiple myeloma 40 | 1,327
nasopharyngeal carcinoma 40 | 1,056
Behcet's syndrome 38 | 50
Carcinoma 38 | 2,147
Asthma 37 | 349
Congenital adrenal hyperplasia 37 | 74
active Crohn's disease 37 | 918
Takayasu's arteritis 36 | 54
Hepatitis B 35 | 103
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
Waldenstrons macroglobulinemia 34 | 764
Alzheimer's disease 33 | 644
sonic hedgehog group medulloblastoma 33 | 1,482
acute myeloid leukemia 32 | 785
esophageal adenocarcinoma 32 | 737
gastric carcinoma 32 | 832
Leprosy 31 | 77
pancreatic carcinoma 31 | 567
Obesity 30 | 616
atypical teratoid/rhabdoid tumor 30 | 1,095
hepatocellular carcinoma 30 | 550
sarcoidosis 30 | 368
spina bifida 30 | 1,064
Atherosclerosis 29 | 275
Duchenne muscular dystrophy 28 | 602
Prostatic Neoplasms 28 | 471
tuberculosis and treatment for 6 months 28 | 686
IGA Glomerulonephritis 27 | 454
posterior fossa group B ependymoma 27 | 1,530

Tissue

Female tissues 500 | 18,646
Urinary Tract 498 | 18,443
Endocrine System 497 | 18,511
Nervous System 497 | 18,560
Digestive Tract 496 | 18,472
Blood and immune system 495 | 17,994
Liver and Pancreas 494 | 18,135
Cardiovascular System 491 | 17,957
Male tissues 490 | 17,968
Skin and soft tissues 487 | 18,114
Respiratory system 486 | 17,483

Target Family

Non-IDG 350 | 11,969
Enzyme 104 | 4,146
Kinase 34 | 634
GPCR 23 | 408
Transcription Factor 19 | 1,400
Transporter 16 | 473
Ion Channel 12 | 341
Epigenetic 5 | 242
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Blood 569 | 569
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein fosB FOSB Tbio Transcription Factor -2.64139 409.7 306
Receptor-interacting serine/threonine-protein kinase 3 RIPK3 Tchem Kinase -2.11581 129.5 456
Sialic acid-binding Ig-like lectin 12 SIGLEC12 Tbio Non-IDG -2.35522 224.6 122
CD40 ligand CD40LG Tchem Non-IDG -4.56976 36580.5 1095
Alternative prion protein PRNP Tbio Non-IDG -3.44085 5471.9 0
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Serpin A9 SERPINA9 Tbio Non-IDG -1.93591 84.3 121
Ankyrin repeat and SOCS box protein 2 ASB2 Tbio Non-IDG -1.40827 27.4 99
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.53667 324.2 196