Development Level

Tbio 255 | 11,651
Tdark 80 | 6,593
Tchem 16 | 1,388
Tclin 1 | 612

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 24 | 979
abnormal heart morphology 6 | 162
increased circulating alkaline... 6 | 122
increased mean corpuscular hem... 6 | 96
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
enlarged heart 5 | 210
abnormal embryo size 4 | 220
abnormal seminal vesicle morph... 4 | 114
decreased vertical activity 4 | 208
edema 4 | 59
increased circulating HDL chol... 4 | 80
increased lean body mass 4 | 172
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
abnormal coat-hair pigmentatio... 3 | 64
abnormal facial morphology 3 | 17
cleft palate 3 | 8
decreased body length 3 | 101
decreased circulating glucose ... 3 | 126
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
enlarged lymph nodes 3 | 37
hyperactivity 3 | 148
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased circulating triglyce... 3 | 42
increased total body fat amoun... 3 | 134
small adrenal glands 3 | 16
small superior vagus ganglion 3 | 74
small thymus 3 | 16
abnormal behavioral response t... 2 | 66
abnormal body wall morphology 2 | 9
abnormal bone structure 2 | 187
abnormal coat- hair morphology 2 | 19
abnormal craniofacial morpholo... 2 | 33
abnormal eye morphology 2 | 68
abnormal lens morphology 2 | 81
abnormal limb bud morphology 2 | 17
abnormal limb morphology 2 | 13
abnormal retina morphology 2 | 71
abnormal retinal vasculature m... 2 | 27
anophthalmia 2 | 33
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating chloride... 2 | 30
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
facial cleft 2 | 3
female infertility 2 | 60
hydrometra 2 | 53
hypoactivity 2 | 132
increased blood uric acid leve... 2 | 5
increased body length 2 | 32
increased circulating LDL chol... 2 | 13
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
male infertility 2 | 123
polydactyly 2 | 7
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small seminal vesicle 2 | 10
small spleen 2 | 19
abnormal cranium morphology 1 | 36
abnormal joint morphology 1 | 23
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
brachydactyly 1 | 19
decreased anxiety-related resp... 1 | 12
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
impaired pupillary reflex 1 | 26
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased red blood cell distr... 1 | 34
long tibia 1 | 25
microphthalmia 1 | 26
prenatal lethality 1 | 28
small kidney 1 | 16
syndactyly 1 | 23
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 232 | 11,493
ovarian cancer 204 | 8,520
osteosarcoma 181 | 7,950
medulloblastoma, large-cell 138 | 6,241
glioblastoma 135 | 5,792
atypical teratoid / rhabdoid tumor 119 | 5,112
ependymoma 115 | 4,679
psoriasis 113 | 6,694
lung cancer 91 | 4,740
Breast cancer 90 | 3,578
group 3 medulloblastoma 88 | 4,104
invasive ductal carcinoma 87 | 2,951
adult high grade glioma 76 | 3,801
malignant mesothelioma 75 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,989
oligodendroglioma 71 | 2,850
non-small cell lung cancer 70 | 2,890
Astrocytoma, Pilocytic 68 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,291
primitive neuroectodermal tumor 62 | 3,035
astrocytic glioma 61 | 2,597
Pick disease 56 | 1,894
lung carcinoma 54 | 2,843
lung adenocarcinoma 52 | 2,716
pancreatic cancer 50 | 2,398
subependymal giant cell astrocytoma 48 | 2,287
group 4 medulloblastoma 47 | 1,855
ductal carcinoma in situ 46 | 1,745
breast carcinoma 44 | 1,638
Kidney cancer 43 | 2,613
pituitary cancer 41 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,962
cystic fibrosis 38 | 1,696
interstitial cystitis 37 | 2,312
tuberculosis 36 | 2,010
Cancer 34 | 2,499
primary pancreatic ductal adenocarcinoma 32 | 1,109
juvenile dermatomyositis 30 | 1,187
Multiple myeloma 29 | 1,332
colon cancer 28 | 1,478
pediatric high grade glioma 28 | 1,064
acute quadriplegic myopathy 27 | 1,158
non primary Sjogren syndrome sicca 25 | 891
acute myeloid leukemia 24 | 783
astrocytoma 24 | 1,146
ulcerative colitis 24 | 1,819
Rheumatoid arthritis 23 | 1,191
spina bifida 23 | 1,074
progressive supranuclear palsy 22 | 676
adrenocortical carcinoma 20 | 1,428
cutaneous lupus erythematosus 20 | 1,057
sonic hedgehog group medulloblastoma 20 | 467
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
dermatomyositis 18 | 966
gastric carcinoma 18 | 807
Atopic dermatitis 17 | 952
Duchenne muscular dystrophy 17 | 601
active ulcerative colitis 17 | 764
gastric cancer 17 | 459
Intellectual disability 16 | 1,016
active Crohn's disease 16 | 922
diabetes mellitus 16 | 1,728
nasopharyngeal carcinoma 16 | 1,058
Schizophrenia 15 | 1,160
primary Sjogren syndrome 15 | 735
Autosomal recessive predisposition 14 | 1,442
aldosterone-producing adenoma 14 | 665
esophageal adenocarcinoma 14 | 737
hepatocellular carcinoma 14 | 547
Alzheimer's disease 13 | 658
Liver Cirrhosis, Experimental 13 | 769
Waldenstrons macroglobulinemia 13 | 765
chronic rhinosinusitis 11 | 512
medulloblastoma 11 | 720
pancreatic carcinoma 11 | 562
Cleft Palate 10 | 271
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Melanoma 10 | 711
Mental and motor retardation 10 | 608
Muscle hypotonia 10 | 571
fibroadenoma 10 | 559
Type 2 diabetes mellitus 9 | 272
limb girdle muscular dystrophy 2A 9 | 213
Autistic Disorder 8 | 364
Cryptorchidism 8 | 296
Down syndrome 8 | 499
Dull intelligence 8 | 645
Endometriosis 8 | 540
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Polycystic ovary syndrome 8 | 360
Poor school performance 8 | 645
Short stature 8 | 531
posterior fossa group A ependymoma 8 | 468
posterior fossa group B ependymoma 8 | 416
tuberculosis and treatment for 3 months 8 | 179
tuberculosis and treatment for 6 months 8 | 409

Tissue

Digestive Tract 347 | 17,369
Endocrine System 347 | 18,159
Female tissues 347 | 17,400
Liver and Pancreas 346 | 16,750
Blood and immune system 345 | 16,909
Skin and soft tissues 345 | 17,230
Male tissues 344 | 17,142
Nervous System 344 | 16,725
Urinary Tract 341 | 16,678
Respiratory system 337 | 16,393
Cardiovascular System 335 | 15,192

Target Family

Non-IDG 217 | 12,091
Enzyme 73 | 4,145
Transcription Factor 33 | 1,400
Epigenetic 10 | 242
Kinase 6 | 634
Transporter 6 | 473
Ion Channel 5 | 344
GPCR 2 | 408

Jensen-KB Tissue

BTO:0000379 352 | 352
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carbonyl reductase family member 4 CBR4 Tbio Enzyme -1.69083 48.5 128
Glucocorticoid modulatory element-binding protein 1 GMEB1 Tbio Transcription Factor -0.75841 7.65 104
Zinc finger protein 777 ZNF777 Tdark Transcription Factor 0.30 0.61 62
Fibronectin type III and SPRY domain-containing protein 1 FSD1 Tbio Non-IDG -1.38197 23.9 160
G patch domain-containing protein 2 GPATCH2 Tdark Non-IDG -0.70852 4.89 36
Zinc finger protein 692 ZNF692 Tdark Transcription Factor -1.12194 12.2 25
Protein quaking QKI Tbio Non-IDG -1.88311 75.1 278
Cyclic AMP-responsive element-binding protein 5 CREB5 Tbio Transcription Factor -0.88055 7.80 164
Signal recognition particle receptor subunit beta SRPRB Tdark Non-IDG -0.45047 3.90 198
Ras-specific guanine nucleotide-releasing factor RalGPS2 RALGPS2 Tdark Non-IDG -0.16734 2.43 84