Development Level

Tbio 241 | 10,625
Tdark 89 | 7,003
Tchem 22 | 1,890
Tclin 1 | 602

Collection

Ion Channel: IDG Consortium (Targets) 2 | 102
GPCR: IDG Consortium (Complete/Control) 1 | 24
GPCR: IDG Consortium (Targets) 1 | 128

IMPC Phenotype

preweaning lethality, complete... 18 | 633
increased circulating HDL chol... 5 | 63
increased mean corpuscular hem... 5 | 93
decreased grip strength 4 | 123
decreased lean body mass 4 | 195
increased or absent threshold ... 4 | 128
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
abnormal coat-hair pigmentatio... 3 | 54
abnormal facial morphology 3 | 9
abnormal lens morphology 3 | 73
cleft palate 3 | 6
decreased body length 3 | 108
decreased bone mineral content 3 | 157
decreased circulating glucose ... 3 | 121
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
increased circulating alkaline... 3 | 119
increased circulating choleste... 3 | 53
polydactyly 3 | 22
short tibia 3 | 82
small adrenal glands 3 | 15
abnormal body wall morphology 2 | 7
abnormal bone structure 2 | 131
abnormal coat- hair morphology 2 | 18
abnormal craniofacial morpholo... 2 | 12
abnormal embryo size 2 | 112
abnormal limb bud morphology 2 | 15
abnormal limb morphology 2 | 7
abnormal retina morphology 2 | 100
abnormal seminal vesicle morph... 2 | 47
anophthalmia 2 | 20
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 32
decreased circulating free fat... 2 | 39
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased lumbar vertebrae num... 2 | 62
edema 2 | 11
enlarged lymph nodes 2 | 27
facial cleft 2 | 3
female infertility 2 | 34
hyperactivity 2 | 108
increased blood uric acid leve... 2 | 5
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased circulating triglyce... 2 | 24
increased mean corpuscular vol... 2 | 91
increased rib number 2 | 41
increased sacral vertebrae num... 2 | 62
increased startle reflex 2 | 38
male infertility 2 | 62
small thymus 2 | 11
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal heart morphology 1 | 51
abnormal sensory capabilities-... 1 | 3
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal vocalization 1 | 21
absent pancreas 1 | 1
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD4-positive, alpha ... 1 | 19
decreased anxiety-related resp... 1 | 12
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
distended jejunum 1 | 1
enlarged cecum 1 | 1
enlarged ileum 1 | 1
hydroencephaly 1 | 6
hydrops fetalis 1 | 22
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased granulocyte number 1 | 8
increased lean body mass 1 | 107
microphthalmia 1 | 15
mydriasis 1 | 9
prenatal lethality prior to he... 1 | 64
small pancreas 1 | 1
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
tremors 1 | 34
trunk curl 1 | 15

Disease

ovarian cancer 203 | 8,491
osteosarcoma 182 | 7,933
medulloblastoma, large-cell 139 | 6,234
glioblastoma 129 | 5,572
psoriasis 113 | 6,685
atypical teratoid / rhabdoid tumor 109 | 4,369
lung cancer 89 | 4,473
invasive ductal carcinoma 86 | 2,950
Breast cancer 84 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,956
malignant mesothelioma 74 | 3,163
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,988
oligodendroglioma 71 | 2,849
ependymoma 68 | 2,514
pilocytic astrocytoma 67 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,289
non-small cell lung cancer 65 | 2,798
pediatric high grade glioma 62 | 2,712
primitive neuroectodermal tumor 62 | 3,031
astrocytic glioma 58 | 2,241
Pick disease 56 | 1,893
lung carcinoma 54 | 2,844
lung adenocarcinoma 52 | 2,714
pancreatic cancer 49 | 2,300
group 3 medulloblastoma 48 | 2,254
subependymal giant cell astrocytoma 47 | 2,287
ductal carcinoma in situ 46 | 1,745
group 4 medulloblastoma 45 | 1,875
breast carcinoma 44 | 1,614
sonic hedgehog group medulloblastoma 44 | 1,482
adult high grade glioma 42 | 2,148
pituitary cancer 41 | 1,972
cystic fibrosis 37 | 1,670
interstitial cystitis 37 | 2,299
primary pancreatic ductal adenocarcinoma 36 | 1,271
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,795
Carcinoma 34 | 2,147
Cancer 32 | 2,346
posterior fossa group A ependymoma 32 | 1,511
posterior fossa group B ependymoma 31 | 1,530
Multiple myeloma 30 | 1,327
juvenile dermatomyositis 30 | 1,189
ulcerative colitis 29 | 2,087
colon cancer 28 | 1,475
acute quadriplegic myopathy 27 | 1,157
astrocytoma 27 | 1,493
medulloblastoma 27 | 1,524
tuberculosis 26 | 1,563
non primary Sjogren syndrome sicca 24 | 840
acute myeloid leukemia 23 | 785
spina bifida 23 | 1,064
Rheumatoid Arthritis 22 | 1,170
progressive supranuclear palsy 22 | 674
adrenocortical carcinoma 20 | 1,427
cutaneous lupus erythematosus 20 | 1,056
atypical teratoid/rhabdoid tumor 18 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
dermatomyositis 18 | 966
gastric carcinoma 18 | 832
Atopic dermatitis 17 | 944
Duchenne muscular dystrophy 17 | 602
diabetes mellitus 17 | 1,663
gastric cancer 17 | 436
active Crohn's disease 16 | 918
nasopharyngeal carcinoma 16 | 1,056
primary Sjogren syndrome 16 | 788
Alzheimer's disease 14 | 644
aldosterone-producing adenoma 14 | 664
esophageal adenocarcinoma 14 | 737
hepatocellular carcinoma 14 | 550
Intellectual disability 13 | 573
Waldenstrons macroglobulinemia 13 | 764
tuberculosis and treatment for 3 months 13 | 327
tuberculosis and treatment for 6 months 13 | 686
active ulcerative colitis 12 | 477
chronic rhinosinusitis 11 | 512
glioblastoma multiforme 11 | 347
pancreatic carcinoma 11 | 567
fibroadenoma 10 | 557
Cleft palate 9 | 125
Down syndrome 8 | 548
Endometriosis 8 | 535
Melanoma 8 | 261
Polycystic Ovary Syndrome 8 | 334
limb girdle muscular dystrophy 2A 8 | 156
non-small cell lung carcinoma 8 | 413
Acquired metabolic disease 7 | 267
Autistic Disorder 7 | 320
Becker muscular dystrophy 7 | 187
Cleft Lip 7 | 91
Craniofacial Abnormalities 7 | 147
Prostatic Neoplasms 7 | 471
Type 2 diabetes mellitus 7 | 192
Amyotrophic Lateral Sclerosis 6 | 432
Crohn's disease 6 | 304
Obesity 6 | 616
Stomach Neoplasms 6 | 282
head and neck cancer 6 | 270
inflammatory breast cancer 6 | 404
urothelial carcinoma 6 | 318

Tissue

Blood and immune system 351 | 17,994
Digestive Tract 351 | 18,472
Endocrine System 351 | 18,511
Female tissues 351 | 18,646
Nervous System 351 | 18,560
Urinary Tract 351 | 18,443
Liver and Pancreas 350 | 18,135
Cardiovascular System 349 | 17,957
Skin and soft tissues 349 | 18,114
Male tissues 348 | 17,968
Respiratory system 347 | 17,483

Target Family

Non-IDG 218 | 11,969
Enzyme 73 | 4,146
Transcription Factor 33 | 1,400
Epigenetic 10 | 242
Kinase 6 | 634
Transporter 6 | 473
Ion Channel 5 | 341
GPCR 2 | 408

Jensen-KB Tissue

BTO:0000379 353 | 353
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.7 122
Ankyrin repeat and SOCS box protein 3 ASB3 Tdark Non-IDG -0.63182 4.84 109
WD repeat-containing protein 70 WDR70 Tdark Non-IDG 0.90 0.28 20
Protein quaking QKI Tbio Non-IDG -1.81649 63.7 254
Cyclic AMP-responsive element-binding protein 5 CREB5 Tbio Transcription Factor -0.80452 6.31 141
Spexin SPX Tbio Non-IDG -2.76281 568.1 18
Histone lysine demethylase PHF8 PHF8 Tchem Epigenetic -1.45177 33.5 70
Protein IWS1 homolog IWS1 Tdark Non-IDG -0.56293 3.84 50
Msx2-interacting protein SPEN Tbio Non-IDG -2.91140 781.7 40
R-spondin-3 RSPO3 Tbio Non-IDG -1.18455 17.3 94