Development Level

Tbio 191 | 10,625
Tdark 39 | 7,003
Tchem 33 | 1,890
Tclin 10 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
decreased body weight 7 | 174
decreased bone mineral content 7 | 157
decreased lean body mass 7 | 195
abnormal bone structure 5 | 131
decreased total body fat amoun... 5 | 186
embryonic lethality prior to t... 5 | 187
increased lean body mass 5 | 107
decreased mean corpuscular hem... 4 | 34
abnormal behavior 3 | 226
abnormal retina morphology 3 | 100
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased mean corpuscular vol... 3 | 50
enlarged heart 3 | 111
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
abnormal thoracic vertebrae mo... 2 | 16
abnormal vocalization 2 | 21
decreased CD4-positive, CD25-p... 2 | 24
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating free fat... 2 | 39
decreased grip strength 2 | 123
decreased heart weight 2 | 44
embryonic lethality prior to o... 2 | 148
increased body length 2 | 20
increased bone mineral content 2 | 92
increased circulating sodium l... 2 | 71
increased effector memory CD4-... 2 | 15
increased monocyte cell number 2 | 27
abnormal coping response 1 | 12
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal pelvic girdle bone mo... 1 | 11
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal tooth morphology 1 | 24
decreased IgG1 level 1 | 4
decreased KLRG1-positive NK ce... 1 | 9
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
edema 1 | 11
enlarged adrenal glands 1 | 3
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hemorrhage 1 | 12
increased CD4-positive, alpha ... 1 | 15
increased Ly6C high monocyte n... 1 | 12
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
pallor 1 | 13
polydactyly 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
tremors 1 | 34
trunk curl 1 | 15
vertebral fusion 1 | 23

Disease

ovarian cancer 148 | 8,484
osteosarcoma 145 | 7,933
psoriasis 93 | 6,685
medulloblastoma, large-cell 92 | 6,234
lung cancer 88 | 4,466
glioblastoma 81 | 5,572
atypical teratoid / rhabdoid tumor 63 | 4,369
interstitial cystitis 61 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
ulcerative colitis 55 | 2,087
Cancer 54 | 2,346
invasive ductal carcinoma 53 | 2,950
malignant mesothelioma 52 | 3,162
Breast cancer 48 | 3,094
cutaneous lupus erythematosus 45 | 1,056
lung carcinoma 45 | 2,844
non-small cell lung cancer 45 | 2,798
subependymal giant cell astrocytoma 44 | 2,287
Multiple myeloma 43 | 1,327
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
primary Sjogren syndrome 43 | 789
group 3 medulloblastoma 41 | 2,254
lung adenocarcinoma 41 | 2,713
Waldenstrons macroglobulinemia 40 | 765
pilocytic astrocytoma 39 | 3,086
Rheumatoid Arthritis 38 | 1,160
pediatric high grade glioma 37 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
adult high grade glioma 34 | 2,148
astrocytoma 33 | 1,493
primitive neuroectodermal tumor 33 | 3,031
diabetes mellitus 31 | 1,663
ductal carcinoma in situ 31 | 1,745
ependymoma 31 | 2,514
tuberculosis 30 | 1,557
pancreatic cancer 29 | 2,300
oligodendroglioma 27 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
Multiple Sclerosis 26 | 498
group 4 medulloblastoma 24 | 1,875
colon cancer 23 | 1,475
cystic fibrosis 23 | 1,665
medulloblastoma 23 | 1,524
breast carcinoma 22 | 1,614
active Crohn's disease 20 | 918
astrocytic glioma 20 | 2,241
dermatomyositis 20 | 933
juvenile dermatomyositis 20 | 1,189
acute myeloid leukemia 19 | 780
Chronic Lymphocytic Leukemia 18 | 242
adrenocortical carcinoma 18 | 1,427
posterior fossa group A ependymoma 18 | 1,511
Carcinoma 17 | 2,147
nasopharyngeal carcinoma 17 | 1,056
tuberculosis and treatment for 6 months 17 | 686
acute quadriplegic myopathy 16 | 1,157
esophageal adenocarcinoma 16 | 737
pituitary cancer 16 | 1,972
Pick disease 15 | 1,893
posterior fossa group B ependymoma 15 | 1,530
primary pancreatic ductal adenocarcinoma 15 | 1,271
Atopic dermatitis 14 | 944
IGA Glomerulonephritis 14 | 454
gastric carcinoma 14 | 832
hepatocellular carcinoma 14 | 532
atypical teratoid/rhabdoid tumor 13 | 1,095
periodontitis 13 | 269
sarcoidosis 13 | 358
sonic hedgehog group medulloblastoma 13 | 1,482
spina bifida 13 | 1,064
Hypersensitivity reaction type II disease 12 | 235
tuberculosis and treatment for 3 months 12 | 327
Alzheimer's disease 11 | 644
Down syndrome 11 | 548
inflammatory breast cancer 11 | 404
mucosa-associated lymphoid tissue lymphoma 11 | 480
Peripheral Neuropathy 10 | 303
pancreatic carcinoma 10 | 567
progressive supranuclear palsy 10 | 674
Asthma 9 | 349
Crohn's disease 9 | 304
Prostatic Neoplasms 9 | 471
Vascular disease 9 | 281
non-small cell lung carcinoma 9 | 413
Duchenne muscular dystrophy 8 | 602
Endometriosis 8 | 535
Intellectual disability 8 | 573
Liver carcinoma 8 | 217
Liver disease 8 | 219
Mammary Neoplasms 8 | 410
Obesity 8 | 616
active ulcerative colitis 8 | 477
chronic lymphosyte leukemia 8 | 232
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
Arthritis 7 | 248
Coronary artery disease 7 | 240
Schizophrenia 7 | 501
aldosterone-producing adenoma 7 | 664
fibroadenoma 7 | 557
gastric cancer 7 | 430

Tissue

Female tissues 270 | 18,647
Urinary Tract 268 | 18,444
Digestive Tract 267 | 18,473
Blood and immune system 266 | 17,995
Endocrine System 266 | 18,512
Nervous System 266 | 18,561
Liver and Pancreas 265 | 18,136
Male tissues 265 | 17,969
Cardiovascular System 264 | 17,958
Respiratory system 264 | 17,484
Skin and soft tissues 264 | 18,115

Target Family

Non-IDG 172 | 11,971
Enzyme 55 | 4,146
Transcription Factor 30 | 1,400
Kinase 8 | 634
Epigenetic 4 | 242
GPCR 2 | 406
Ion Channel 1 | 341
Transporter 1 | 473

Jensen-KB Tissue

B-lymphocyte cell line 273 | 273
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 148 ZNF148 Tbio Transcription Factor -1.71996 60.7 178
Interleukin-1 receptor type 2 IL1R2 Tbio Non-IDG -1.85724 72.1 361
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60
39S ribosomal protein L19, mitochondrial MRPL19 Tbio Non-IDG -0.91149 8.14 108
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Septin-1 SEPT1 Tdark Non-IDG -1.92957 87.4 0
Tapasin TAPBP Tbio Non-IDG -2.50535 373.6 134
Suppressor of cytokine signaling 1 SOCS1 Tbio Non-IDG -3.00271 1072.1 392
C-type lectin-like domain family 1 CLECL1 Tdark Non-IDG 0.13 1.63 37
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.16239 168.2 0