Development Level

Tbio 191 | 10,625
Tdark 39 | 7,003
Tchem 33 | 1,890
Tclin 10 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 26
Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 633
decreased body weight 7 | 174
decreased bone mineral content 7 | 157
decreased lean body mass 7 | 195
abnormal bone structure 5 | 131
decreased total body fat amoun... 5 | 186
embryonic lethality prior to t... 5 | 187
increased lean body mass 5 | 107
decreased mean corpuscular hem... 4 | 34
abnormal behavior 3 | 226
abnormal retina morphology 3 | 100
decreased circulating alkaline... 3 | 41
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased mean corpuscular vol... 3 | 50
enlarged heart 3 | 111
increased mean corpuscular vol... 3 | 91
increased or absent threshold ... 3 | 128
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
abnormal retinal pigmentation 2 | 61
abnormal thoracic vertebrae mo... 2 | 16
abnormal vocalization 2 | 21
decreased CD4-positive, CD25-p... 2 | 24
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating free fat... 2 | 39
decreased grip strength 2 | 123
decreased heart weight 2 | 44
embryonic lethality prior to o... 2 | 148
increased body length 2 | 20
increased bone mineral content 2 | 92
increased circulating sodium l... 2 | 71
increased effector memory CD4-... 2 | 15
increased monocyte cell number 2 | 27
abnormal coping response 1 | 12
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal pelvic girdle bone mo... 1 | 11
abnormal rib morphology 1 | 28
abnormal skin appearance 1 | 8
abnormal tooth morphology 1 | 24
decreased IgG1 level 1 | 4
decreased KLRG1-positive NK ce... 1 | 9
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
edema 1 | 11
enlarged adrenal glands 1 | 3
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hemorrhage 1 | 12
increased CD4-positive, alpha ... 1 | 15
increased Ly6C high monocyte n... 1 | 12
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating total pr... 1 | 20
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 9
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
pallor 1 | 13
polydactyly 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
tremors 1 | 34
trunk curl 1 | 15
vertebral fusion 1 | 23

Disease

ovarian cancer 148 | 8,491
osteosarcoma 145 | 7,933
psoriasis 93 | 6,685
medulloblastoma, large-cell 92 | 6,234
lung cancer 88 | 4,473
glioblastoma 81 | 5,572
atypical teratoid / rhabdoid tumor 63 | 4,369
interstitial cystitis 61 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
ulcerative colitis 55 | 2,087
Cancer 54 | 2,346
invasive ductal carcinoma 53 | 2,950
malignant mesothelioma 52 | 3,163
Breast cancer 48 | 3,098
cutaneous lupus erythematosus 45 | 1,056
lung carcinoma 45 | 2,844
non-small cell lung cancer 45 | 2,798
subependymal giant cell astrocytoma 44 | 2,287
Multiple myeloma 43 | 1,327
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
primary Sjogren syndrome 43 | 788
lung adenocarcinoma 42 | 2,714
group 3 medulloblastoma 41 | 2,254
Waldenstrons macroglobulinemia 40 | 764
pilocytic astrocytoma 39 | 3,086
Rheumatoid Arthritis 38 | 1,170
pediatric high grade glioma 37 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,956
adult high grade glioma 34 | 2,148
astrocytoma 33 | 1,493
primitive neuroectodermal tumor 33 | 3,031
diabetes mellitus 31 | 1,663
ductal carcinoma in situ 31 | 1,745
ependymoma 31 | 2,514
tuberculosis 30 | 1,563
pancreatic cancer 29 | 2,300
oligodendroglioma 27 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
Multiple Sclerosis 26 | 498
group 4 medulloblastoma 24 | 1,875
colon cancer 23 | 1,475
cystic fibrosis 23 | 1,670
medulloblastoma 23 | 1,524
breast carcinoma 22 | 1,614
active Crohn's disease 20 | 918
astrocytic glioma 20 | 2,241
dermatomyositis 20 | 966
juvenile dermatomyositis 20 | 1,189
acute myeloid leukemia 19 | 785
adrenocortical carcinoma 18 | 1,427
chronic lymphocytic leukemia 18 | 244
posterior fossa group A ependymoma 18 | 1,511
Carcinoma 17 | 2,147
nasopharyngeal carcinoma 17 | 1,056
tuberculosis and treatment for 6 months 17 | 686
acute quadriplegic myopathy 16 | 1,157
esophageal adenocarcinoma 16 | 737
pituitary cancer 16 | 1,972
Pick disease 15 | 1,893
hepatocellular carcinoma 15 | 550
posterior fossa group B ependymoma 15 | 1,530
primary pancreatic ductal adenocarcinoma 15 | 1,271
Atopic dermatitis 14 | 944
IGA Glomerulonephritis 14 | 454
gastric carcinoma 14 | 832
atypical teratoid/rhabdoid tumor 13 | 1,095
periodontitis 13 | 269
sarcoidosis 13 | 368
sonic hedgehog group medulloblastoma 13 | 1,482
spina bifida 13 | 1,064
Hypersensitivity reaction type II disease 12 | 235
tuberculosis and treatment for 3 months 12 | 327
Alzheimer's disease 11 | 644
Down syndrome 11 | 548
inflammatory breast cancer 11 | 404
mucosa-associated lymphoid tissue lymphoma 11 | 480
Peripheral Neuropathy 10 | 303
pancreatic carcinoma 10 | 567
progressive supranuclear palsy 10 | 674
systemic lupus erythematosus 10 | 172
Asthma 9 | 349
Crohn's disease 9 | 304
Prostatic Neoplasms 9 | 471
Vascular disease 9 | 281
non-small cell lung carcinoma 9 | 413
Duchenne muscular dystrophy 8 | 602
Endometriosis 8 | 535
Intellectual disability 8 | 573
Liver carcinoma 8 | 217
Liver disease 8 | 219
Mammary Neoplasms 8 | 410
Obesity 8 | 616
active ulcerative colitis 8 | 477
chronic lymphosyte leukemia 8 | 232
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
Arthritis 7 | 248
Schizophrenia 7 | 503
aldosterone-producing adenoma 7 | 664
fibroadenoma 7 | 557
gastric cancer 7 | 436

Tissue

Female tissues 270 | 18,646
Urinary Tract 268 | 18,443
Digestive Tract 267 | 18,472
Blood and immune system 266 | 17,994
Endocrine System 266 | 18,511
Nervous System 266 | 18,560
Liver and Pancreas 265 | 18,135
Male tissues 265 | 17,968
Cardiovascular System 264 | 17,957
Respiratory system 264 | 17,483
Skin and soft tissues 264 | 18,114

Target Family

Non-IDG 172 | 11,969
Enzyme 55 | 4,146
Transcription Factor 30 | 1,400
Kinase 8 | 634
Epigenetic 4 | 242
GPCR 2 | 408
Ion Channel 1 | 341
Transporter 1 | 473

Jensen-KB Tissue

B-lymphocyte cell line 273 | 273
Brain 7,307 | 7,307
Liver 4,987 | 4,987
Cervical carcinoma cell 4,914 | 4,914
Erythroleukemia cell 4,273 | 4,273
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,281 | 2,281
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 827 | 827
Muscle 721 | 721
Pronephros 714 | 714
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 569 | 569
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
Hepatoma cell 242 | 242
Urinary bladder 225 | 225
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein ZFP69B ZFP69B Tdark Transcription Factor 0.00000 60
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.21810 149.4 267
EF-hand calcium-binding domain-containing protein 11 EFCAB11 Tdark Non-IDG -0.02511 1.12 5
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.76199 528.6 688
Erbin ERBIN Tbio Non-IDG -1.68182 53.5 111
Glycerophosphodiester phosphodiesterase 1 GDE1 Tbio Enzyme -1.03941 11.9 104
Nesprin-3 SYNE3 Tbio Non-IDG -0.90535 8.74 91
Cell division cycle-associated protein 4 CDCA4 Tbio Non-IDG -1.01464 12.4 126
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.11491 14.8 25
Septin-1 SEPT1 Tdark Non-IDG -1.97919 87.4 0