Development Level

Tbio 107 | 11,445
Tchem 11 | 1,598
Tdark 11 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to t... 5 | 278
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased total body fat amoun... 3 | 207
embryonic growth retardation 3 | 106
increased lean body mass 3 | 172
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased circulating sodium l... 2 | 22
increased blood urea nitrogen ... 2 | 48
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
absent pinna reflex 1 | 23
brachydactyly 1 | 19
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
edema 1 | 59
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
macrophthalmia 1 | 2
mammalian phenotype 1 | 17
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
syndactyly 1 | 23

Disease

ovarian cancer 87 | 8,520
Carcinoma 74 | 11,493
osteosarcoma 59 | 7,950
lung cancer 56 | 4,740
medulloblastoma, large-cell 50 | 6,241
Multiple myeloma 44 | 1,332
glioblastoma 42 | 5,792
psoriasis 42 | 6,694
ependymoma 35 | 4,679
Cancer 34 | 2,499
atypical teratoid / rhabdoid tumor 34 | 5,112
group 3 medulloblastoma 31 | 4,104
Breast cancer 30 | 3,578
lung adenocarcinoma 29 | 2,716
Waldenstrons macroglobulinemia 28 | 765
astrocytoma 27 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
oligodendroglioma 26 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
dermatomyositis 24 | 966
diabetes mellitus 23 | 1,728
non-small cell lung cancer 22 | 2,890
pancreatic cancer 22 | 2,398
invasive ductal carcinoma 21 | 2,951
primitive neuroectodermal tumor 21 | 3,035
acute quadriplegic myopathy 20 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
malignant mesothelioma 20 | 3,232
astrocytic glioma 19 | 2,597
subependymal giant cell astrocytoma 19 | 2,287
Pick disease 18 | 1,894
adult high grade glioma 16 | 3,801
Astrocytoma, Pilocytic 15 | 3,081
breast carcinoma 15 | 1,638
colon cancer 15 | 1,478
group 4 medulloblastoma 15 | 1,855
interstitial cystitis 14 | 2,312
juvenile dermatomyositis 14 | 1,187
tuberculosis 14 | 2,010
Autosomal recessive predisposition 13 | 1,442
Rheumatoid arthritis 13 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
nasopharyngeal carcinoma 12 | 1,058
primary pancreatic ductal adenocarcinoma 12 | 1,109
Kidney cancer 11 | 2,613
cystic fibrosis 11 | 1,696
lung carcinoma 11 | 2,843
pediatric high grade glioma 11 | 1,064
ulcerative colitis 11 | 1,819
Liver Cirrhosis, Experimental 10 | 769
Animal Mammary Neoplasms 9 | 136
Duchenne muscular dystrophy 9 | 601
Mammary Neoplasms, Animal 9 | 136
Mammary Neoplasms, Experimental 9 | 154
acute myeloid leukemia 9 | 783
ductal carcinoma in situ 9 | 1,745
non primary Sjogren syndrome sicca 9 | 891
primary Sjogren syndrome 9 | 735
Adenocarcinoma of lung 8 | 142
Breast Neoplasms 8 | 445
Disease Models, Animal 8 | 155
Down syndrome 8 | 499
HIV Infections 8 | 102
Intellectual disability 8 | 1,016
Mammary Neoplasms 8 | 425
adrenocortical carcinoma 8 | 1,428
hereditary spastic paraplegia 8 | 318
pituitary cancer 8 | 1,972
Epilepsy 7 | 792
Stomach Neoplasms 7 | 300
Bipolar Disorder 6 | 666
Muscle hypotonia 6 | 571
Osteoporosis 6 | 363
Schizophrenia 6 | 1,160
active Crohn's disease 6 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
sonic hedgehog group medulloblastoma 6 | 467
Alzheimer's disease 5 | 658
Cognitive delay 5 | 608
Degenerative polyarthritis 5 | 115
Global developmental delay 5 | 608
Immune system cancer 5 | 140
Mental and motor retardation 5 | 608
Neoplasm Invasiveness 5 | 161
Obesity 5 | 678
Osteoarthritis 5 | 184
Seizures 5 | 596
inflammatory breast cancer 5 | 286
medulloblastoma 5 | 720
mucosa-associated lymphoid tissue lymphoma 5 | 484
non-small cell lung carcinoma 5 | 317
periodontitis 5 | 293
tuberculosis and treatment for 6 months 5 | 409
Chronic Lymphocytic Leukemia 4 | 262
Dull intelligence 4 | 645
Myocardial Ischemia 4 | 169
Prostatic Neoplasms 4 | 495
hepatocellular carcinoma 4 | 547
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074

Tissue

Digestive Tract 127 | 17,369
Endocrine System 127 | 18,159
Nervous System 127 | 16,725
Blood and immune system 126 | 16,909
Cardiovascular System 126 | 15,192
Female tissues 126 | 17,400
Liver and Pancreas 126 | 16,750
Male tissues 126 | 17,142
Respiratory system 126 | 16,393
Skin and soft tissues 126 | 17,230
Urinary Tract 126 | 16,678

Target Family

Non-IDG 88 | 12,091
Enzyme 31 | 4,145
Transporter 6 | 473
Transcription Factor 3 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634

Jensen-KB Tissue

B-cell lymphoma cell 130 | 130
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
Exportin-T XPOT Tbio Non-IDG -1.46210 29.6 86
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Redox-regulatory protein FAM213A FAM213A Tbio Non-IDG -1.51277 30.6 63
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Prenylcysteine oxidase 1 PCYOX1 Tbio Enzyme -0.61256 4.78 50
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Tyrosine--tRNA ligase, cytoplasmic YARS Tchem Enzyme -2.45633 272.6 180