Development Level

Tbio 32 | 11,445
Tchem 11 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal embryo size 3 | 220
preweaning lethality, complete... 3 | 979
decreased circulating triglyce... 2 | 79
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal coat appearance 1 | 31
abnormal hindlimb morphology 1 | 2
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased cardiac muscle contr... 1 | 8
increased circulating serum al... 1 | 22
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 30 | 8,520
Carcinoma 26 | 11,493
osteosarcoma 22 | 7,950
glioblastoma 21 | 5,792
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
medulloblastoma, large-cell 19 | 6,241
ependymoma 16 | 4,679
lung cancer 16 | 4,740
Cancer 15 | 2,499
adult high grade glioma 13 | 3,801
pancreatic cancer 13 | 2,398
Astrocytoma, Pilocytic 12 | 3,081
Breast cancer 12 | 3,578
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
astrocytic glioma 11 | 2,597
diabetes mellitus 11 | 1,728
oligodendroglioma 11 | 2,850
pituitary cancer 11 | 1,972
malignant mesothelioma 10 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
juvenile dermatomyositis 8 | 1,187
lung carcinoma 8 | 2,843
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung adenocarcinoma 7 | 2,716
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
Melanoma 6 | 711
Multiple myeloma 6 | 1,332
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
primitive neuroectodermal tumor 6 | 3,035
Amyotrophic lateral sclerosis 5 | 451
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Rheumatoid arthritis 5 | 1,191
Vascular disease 5 | 319
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 807
nasopharyngeal carcinoma 5 | 1,058
Alcoholic Intoxication, Chronic 4 | 289
Alzheimer's disease 4 | 658
Breast Neoplasms 4 | 445
Eye disease 4 | 62
Lung Neoplasms 4 | 232
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Neurodegenerative disease 4 | 414
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 764
group 4 medulloblastoma 4 | 1,855
limb girdle muscular dystrophy 2A 4 | 213
Atherosclerosis 3 | 291
Becker muscular dystrophy 3 | 191
Bipolar Disorder 3 | 666
Brain Ischemia 3 | 110
Dementia 3 | 175
Endometriosis 3 | 540
Epilepsy 3 | 792
Hypertension 3 | 396
Major Depressive Disorder 3 | 301
Mouth Neoplasms 3 | 55
Multiple Sclerosis 3 | 540
Muscle Spasticity 3 | 195
Neoplasm Invasiveness 3 | 161
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Skeletal muscle atrophy 3 | 139
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
chronic lymphosyte leukemia 3 | 204
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
muscle degeneration 3 | 139
pediatric high grade glioma 3 | 1,064
periodontitis 3 | 293

Tissue

Endocrine System 48 | 18,159
Liver and Pancreas 48 | 16,750
Male tissues 48 | 17,142
Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Female tissues 47 | 17,400
Nervous System 47 | 16,725
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Respiratory system 46 | 16,393
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 10 | 4,145
Kinase 4 | 634
Transcription Factor 4 | 1,400
Transporter 1 | 473

Jensen-KB Tissue

Astrocytoma cell 48 | 48
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
R-spondin-4 RSPO4 Tbio Non-IDG -1.45244 28.7 66
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
Uncharacterized protein C19orf47 C19orf47 Tdark Non-IDG 0.00000 79
Transmembrane protein 102 TMEM102 Tbio Non-IDG -1.22014 17.5 71
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Contactin-associated protein-like 3B CNTNAP3B Tdark Non-IDG 0.00000 18
Neuroblastoma suppressor of tumorigenicity 1 NBL1 Tbio Non-IDG -2.58132 362.9 217
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
WD repeat-containing protein 62 WDR62 Tbio Non-IDG -1.43806 35.5 33
Probable ATP-dependent RNA helicase DDX56 DDX56 Tbio Enzyme -0.74504 5.47 246