Development Level

Tbio 15 | 10,625
Tdark 7 | 7,003
Tchem 3 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 2 | 226
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
hyperactivity 2 | 108
increased lean body mass 2 | 107
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
increased circulating alkaline... 1 | 119
increased eosinophil cell numb... 1 | 9
increased mean corpuscular hem... 1 | 93
increased total body fat amoun... 1 | 57
preweaning lethality, complete... 1 | 633
short tibia 1 | 82

Disease

ovarian cancer 17 | 8,484
osteosarcoma 16 | 7,933
glioblastoma 15 | 5,572
medulloblastoma, large-cell 13 | 6,234
Breast cancer 10 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
psoriasis 10 | 6,685
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
invasive ductal carcinoma 8 | 2,950
lung cancer 8 | 4,466
Cancer 7 | 2,346
atypical teratoid / rhabdoid tumor 7 | 4,369
cystic fibrosis 7 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
adult high grade glioma 6 | 2,148
breast carcinoma 6 | 1,614
medulloblastoma 6 | 1,524
pilocytic astrocytoma 6 | 3,086
ulcerative colitis 6 | 2,087
Rheumatoid Arthritis 5 | 1,160
acute quadriplegic myopathy 5 | 1,157
dermatomyositis 5 | 933
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
lung adenocarcinoma 5 | 2,713
non-small cell lung cancer 5 | 2,798
primitive neuroectodermal tumor 5 | 3,031
Carcinoma 4 | 2,147
Multiple myeloma 4 | 1,327
Pick disease 4 | 1,893
adrenocortical carcinoma 4 | 1,427
colon cancer 4 | 1,475
interstitial cystitis 4 | 2,299
juvenile dermatomyositis 4 | 1,189
oligodendroglioma 4 | 2,849
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
sarcoidosis 4 | 358
Amyotrophic Lateral Sclerosis 3 | 431
Duchenne muscular dystrophy 3 | 602
Multiple Sclerosis 3 | 498
Neurodegenerative disease 3 | 383
active Crohn's disease 3 | 918
aldosterone-producing adenoma 3 | 664
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
cutaneous lupus erythematosus 3 | 1,056
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,875
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,162
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 674
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,557
Alzheimer's disease 2 | 644
Barrett's esophagus 2 | 183
Cardiovascular system disease 2 | 194
Contact Dermatitis 2 | 80
Down syndrome 2 | 548
Hypersensitivity reaction type II disease 2 | 235
Lung disease 2 | 132
Myocardial Ischemia 2 | 169
Neuropathy 2 | 210
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
hereditary spastic paraplegia 2 | 313
nasopharyngeal carcinoma 2 | 1,056
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
sonic hedgehog group medulloblastoma 2 | 1,482
Adenoma 1 | 165
Autoimmune Diseases 1 | 33
Cerebrovascular accident 1 | 44
Coronary heart disease 1 | 59
Cutis laxa 1 | 28
Degenerative polyarthritis 1 | 93
Dermatitis 1 | 107
Distal arthrogryposis 1 | 45
Epilepsy 1 | 346
Glycogen storage disease 1 | 37
Hypersensitivity 1 | 63
Inflammatory bowel disease 1 | 142
Liver carcinoma 1 | 217
Megalocornea 1 | 15
Mesothelioma 1 | 40
Microcephaly 1 | 149
Myopathy 1 | 128
Paraplegia 1 | 71
Pneumonia 1 | 133
Ptosis 1 | 42
adrenocortical adenoma 1 | 134
atypical teratoid/rhabdoid tumor 1 | 1,095
limb girdle muscular dystrophy 2A 1 | 156
pulmonary arterial hypertension 1 | 36
severe Alzheimer's disease 1 | 49
substance-related disorder 1 | 105

Tissue

Blood and immune system 26 | 17,995
Cardiovascular System 26 | 17,958
Digestive Tract 26 | 18,473
Endocrine System 26 | 18,512
Female tissues 26 | 18,647
Liver and Pancreas 26 | 18,136
Male tissues 26 | 17,969
Nervous System 26 | 18,561
Respiratory system 26 | 17,484
Skin and soft tissues 26 | 18,115
Urinary Tract 26 | 18,444

Target Family

Non-IDG 19 | 11,971
Enzyme 3 | 4,146
Kinase 2 | 634
GPCR 1 | 406
Transcription Factor 1 | 1,400

Jensen-KB Tissue

Astrocyte 26 | 26
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
DNA dC->dU-editing enzyme APOBEC-3H APOBEC3H Tbio Non-IDG -1.50658 37.9 18
C-X-C chemokine receptor type 3 CXCR3 Tchem GPCR -2.81018 788.3 508
UPF0606 protein KIAA1549L KIAA1549L Tdark Non-IDG -0.17609 1.22 7
Protein AHNAK2 AHNAK2 Tdark Non-IDG -0.55630 3.31 58
Dynamin-2 DNM2 Tchem Non-IDG -3.22299 1426.1 125
Protein ZGRF1 ZGRF1 Tdark Non-IDG 0.50 0.58 81
Casein kinase I isoform gamma-3 CSNK1G3 Tbio Kinase -1.01072 9.69 121
Autophagy-related protein 16-2 ATG16L2 Tbio Non-IDG -0.80106 6.87 115
Protein Hook homolog 3 HOOK3 Tbio Non-IDG -0.94962 0.00000 55