Development Level

Tbio 57 | 10,625
Tdark 16 | 7,003
Tchem 9 | 1,890
Tclin 2 | 602

IMPC Term

preweaning lethality, complete... 3 | 633
decreased grip strength 2 | 123
abnormal bone structure 1 | 131
abnormal iron homeostasis 1 | 1
abnormal posture 1 | 5
abnormal radius morphology 1 | 8
decreased CD4-positive NK T ce... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased Ly6C-positive immatu... 1 | 4
decreased Ly6C-positive mature... 1 | 4
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased effector memory CD8-... 1 | 24
decreased lean body mass 1 | 195
decreased marginal zone B cell... 1 | 1
decreased marginal zone precur... 1 | 1
decreased mature B cell number 1 | 25
decreased memory-marker CD4-po... 1 | 4
embryonic lethality prior to t... 1 | 187
increased CD4-negative NK T ce... 1 | 4
increased CD4-positive, alpha ... 1 | 15
increased CD5-positive Ly6C-po... 1 | 4
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive T-hel... 1 | 2
increased Ly6C high monocyte n... 1 | 12
increased circulating triglyce... 1 | 24
increased effector memory T-he... 1 | 5
increased follicular B cell nu... 1 | 1
increased plasma cell number 1 | 5
increased transitional stage T... 1 | 1
long tibia 1 | 13
short tibia 1 | 82
thrombocytopenia 1 | 46

Disease

ovarian cancer 56 | 8,484
osteosarcoma 41 | 7,933
medulloblastoma, large-cell 32 | 6,234
psoriasis 30 | 6,685
glioblastoma 29 | 5,572
Breast cancer 27 | 3,094
atypical teratoid / rhabdoid tumor 24 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
invasive ductal carcinoma 23 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
lung adenocarcinoma 19 | 2,713
lung cancer 19 | 4,466
pancreatic cancer 19 | 2,300
malignant mesothelioma 18 | 3,162
pilocytic astrocytoma 17 | 3,086
Cancer 16 | 2,346
group 3 medulloblastoma 15 | 2,254
primary pancreatic ductal adenocarcinoma 15 | 1,271
oligodendroglioma 14 | 2,849
Multiple myeloma 13 | 1,327
breast carcinoma 13 | 1,614
cystic fibrosis 13 | 1,665
lung carcinoma 13 | 2,844
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
pediatric high grade glioma 13 | 2,712
Pick disease 12 | 1,893
non-small cell lung cancer 12 | 2,798
sonic hedgehog group medulloblastoma 12 | 1,482
subependymal giant cell astrocytoma 12 | 2,287
adrenocortical carcinoma 11 | 1,427
ependymoma 11 | 2,514
interstitial cystitis 11 | 2,299
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,031
active Crohn's disease 10 | 918
astrocytoma 10 | 1,493
ulcerative colitis 10 | 2,087
Duchenne muscular dystrophy 9 | 602
acute quadriplegic myopathy 9 | 1,157
adult high grade glioma 9 | 2,148
diabetes mellitus 9 | 1,663
ductal carcinoma in situ 9 | 1,745
posterior fossa group A ependymoma 9 | 1,511
Atopic dermatitis 8 | 944
astrocytic glioma 8 | 2,241
colon cancer 8 | 1,475
dermatomyositis 8 | 933
juvenile dermatomyositis 8 | 1,189
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
group 4 medulloblastoma 7 | 1,875
hepatocellular carcinoma 7 | 532
medulloblastoma 7 | 1,524
posterior fossa group B ependymoma 7 | 1,530
Becker muscular dystrophy 6 | 187
Carcinoma 6 | 2,147
Lung Neoplasms 6 | 171
atypical teratoid/rhabdoid tumor 6 | 1,095
gastric carcinoma 6 | 832
nasopharyngeal carcinoma 6 | 1,056
spina bifida 6 | 1,064
Alzheimer's disease 5 | 644
Amyotrophic Lateral Sclerosis 5 | 431
Endometriosis 5 | 535
cutaneous lupus erythematosus 5 | 1,056
mucosa-associated lymphoid tissue lymphoma 5 | 480
progressive supranuclear palsy 5 | 674
tuberculosis 5 | 1,557
Atherosclerosis 4 | 275
Hypertension 4 | 287
IGA Glomerulonephritis 4 | 454
Intellectual disability 4 | 573
Kidney disease 4 | 396
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,160
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
fibroadenoma 4 | 557
non primary Sjogren syndrome sicca 4 | 840
pancreatic carcinoma 4 | 567
urothelial carcinoma 4 | 318
Anemia 3 | 252
Cardiovascular system disease 3 | 194
Chronic Lymphocytic Leukemia 3 | 242
Colonic Neoplasms 3 | 126
Colorectal Neoplasms 3 | 217
Down syndrome 3 | 548
Liver carcinoma 3 | 217
Mesothelioma 3 | 40
Parkinson Disease 3 | 102
Parkinson's disease 3 | 364
active ulcerative colitis 3 | 477
aldosterone-producing adenoma 3 | 664
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 430
glioblastoma multiforme 3 | 347
primary Sjogren syndrome 3 | 789
pterygium 3 | 74
type II diabetes mellitus and post-ischemic heart failure 3 | 89

Tissue

Liver and Pancreas 83 | 18,136
Male tissues 83 | 17,969
Nervous System 83 | 18,561
Blood and immune system 82 | 17,995
Cardiovascular System 82 | 17,958
Digestive Tract 82 | 18,473
Female tissues 82 | 18,647
Endocrine System 81 | 18,512
Respiratory system 81 | 17,484
Skin and soft tissues 81 | 18,115
Urinary Tract 81 | 18,444

Target Family

Non-IDG 57 | 11,971
Enzyme 22 | 4,146
Epigenetic 2 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
Transporter 1 | 473

Jensen-KB Tissue

Aorta 84 | 84
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 PLCD1 Tchem Enzyme -2.16125 137.5 96
Calponin-1 CNN1 Tbio Non-IDG -2.15513 149.7 268
Beta-galactosidase-1-like protein 2 GLB1L2 Tdark Enzyme 0.06 0.72 53
ORM1-like protein 2 ORMDL2 Tdark Non-IDG 0.10 0.57 46
SEC23-interacting protein SEC23IP Tbio Non-IDG -0.83431 6.51 123
Protein misato homolog 1 MSTO1 Tdark Non-IDG -1.74451 53.5 48
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial MCCC1 Tbio Enzyme -1.88980 79.8 80
26S protease regulatory subunit 10B PSMC6 Tchem Enzyme -2.64753 334.8 203
Ribosomal biogenesis protein LAS1L LAS1L Tdark Non-IDG -0.43820 2.84 94
Coatomer subunit beta COPB1 Tbio Non-IDG -1.91574 82.6 130